Systemic Inflammation is Associated with Cardiometabolic Risk Factors and Clinical Outcomes

References

• Frostegard J. Immunity, atherosclerosis and cardiovascular disease. BMC Med. 2013;11(117). doi:10.1186/1741-7015-11-117
   PubMed Web of Science ®Google Scholar
• Ruparelia N, Chai JT, Fisher EA, Choudhury RP. Inflammatory processes in cardiovascular disease: a route to targeted therapies. Nat Rev Cardiol. 2017;14. doi:10.1038/nrcardio.2016.185
   Web of Science ®Google Scholar
• Li J, Lee DH, Hu J, et al. Dietary inflammatory potential and risk of cardiovascular disease among men and women in the U.S. J Am Coll Cardiol. 2020;76:2181–2193. doi:10.1016/j.jacc.2020.09.535
   PubMed Web of Science ®Google Scholar
• Stenvinkel P, Chertow GM, Devarajan P, et al. Chronic inflammation in chronic kidney disease progression: role of Nrf2. Kidney Int Rep. 2021;6:1775–1787. doi:10.1016/j.ekir.2021.04.023
   PubMed Web of Science ®Google Scholar
• Huang Y, Zeng M, Zhang L, et al. Dietary inflammatory potential is associated with sarcopenia among chronic kidney disease population. Front Nutr. 2022;9(856726). doi:10.3389/fnut.2022.856726
   Web of Science ®Google Scholar
• Martini S, Nair V, Keller BJ, et al. Integrative biology identifies shared transcriptional networks in CKD. J Am Soc Nephrol. 2014;25:2559–2572. doi:10.1681/ASN.2013080906
   PubMed Web of Science ®Google Scholar
• Zhang J, Xu Q, Sun W, et al. New insights into the role of NLRP3 inflammasome in pathogenesis and treatment of chronic obstructive pulmonary disease. J Inflamm Res. 2021;14:4155–4168. doi:10.2147/JIR.S324323
   PubMed Web of Science ®Google Scholar
• Lubberts E, van den Berg WB. Cytokines in the pathogenesis of rheumatoid arthritis and collagen-induced arthritis. Adv Exp Med Biol. 2003;520:194–202. doi:10.1007/978-1-4615-0171-8_11
   PubMed Web of Science ®Google Scholar
• Jin Z, Wu Q, Chen S, et al. The associations of two novel inflammation indexes, sii and siri with the risks for cardiovascular diseases and all-cause mortality: a ten-year follow-up study in 85,154 Individuals. J Inflamm Res. 2021;14:131–140. doi:10.2147/JIR.S283835
   PubMed Web of Science ®Google Scholar
• Arroyo-Espliguero R, Avanzas P, Quiles J, Kaski JC. Predictive value of coronary artery stenoses and C-reactive protein levels in patients with stable coronary artery disease. Atherosclerosis. 2009;204:239–243. doi:10.1016/j.atherosclerosis.2008.08.009
   PubMed Web of Science ®Google Scholar
• Su B, Liu T, Chen F, et al. Inflammatory markers and the risk of chronic obstructive pulmonary disease: a systematic review and meta-analysis. PLoS One. 2016;11(e0150586). doi:10.1371/journal.pone.0150586
   Web of Science ®Google Scholar
• Wang X, Bao W, Liu J, et al. Inflammatory markers and risk of type 2 diabetes: a systematic review and meta-analysis. Diabetes Care. 2013;36:166–175. doi:10.2337/dc12-0702
   PubMed Web of Science ®Google Scholar
• Nozoe T, Matono R, Ijichi H, Ohga T, Ezaki T. Glasgow Prognostic Score (GPS) can be a useful indicator to determine prognosis of patients with colorectal carcinoma. Int Surg. 2014;99:512–517. doi:10.9738/INTSURG-D-13-00118.1
   PubMed Web of Science ®Google Scholar
• Bonaccio M, Di Castelnuovo A, Pounis G, et al. A score of low-grade inflammation and risk of mortality: prospective findings from the Moli-sani study. Haematologica. 2016;101:1434–1441. doi:10.3324/haematol.2016.144055
   PubMed Web of Science ®Google Scholar
• Conen D, Ridker PM, Everett BM, et al. A multimarker approach to assess the influence of inflammation on the incidence of atrial fibrillation in women. Eur Heart J. 2010;31:1730–1736. doi:10.1093/eurheartj/ehq146
   PubMed Web of Science ®Google Scholar
• Crouch SH, Botha-Le Roux S, Delles C, Graham LA, Schutte AE. Inflammation and hypertension development: a longitudinal analysis of the African-PREDICT study. Int J Cardiol Hypertens. 2020;7:100067. doi:10.1016/j.ijchy.2020.100067
   PubMedGoogle Scholar
• Sanders-van Wijk S, Tromp J, Beussink-Nelson L, et al. Proteomic evaluation of the comorbidity-inflammation paradigm in heart failure with preserved ejection fraction: results from the PROMIS-HFpEF Study. Circulation. 2020;142:2029–2044. doi:10.1161/CIRCULATIONAHA.120.045810
   PubMed Web of Science ®Google Scholar
• Faria AP, Ritter AMV, Gasparetti CS, et al. A proposed inflammatory score of circulating cytokines/adipokines associated with resistant hypertension, but dependent on obesity parameters. Arq Bras Cardiol. 2019;112. doi:10.5935/abc.20190032
   PubMed Web of Science ®Google Scholar
• Ho JE, Lyass A, Courchesne P, et al. Protein biomarkers of cardiovascular disease and mortality in the community. J Am Heart Assoc. 2018;7. doi:10.1161/JAHA.117.008108
   Web of Science ®Google Scholar
• Yao C, Chen G, Song C, et al. Genome-wide mapping of plasma protein QTLs identifies putatively causal genes and pathways for cardiovascular disease. Nat Commun. 2018;9(3268). doi:10.1038/s41467-018-05512-x
   Web of Science ®Google Scholar
• Rost NS, Wolf PA, Kase CS, et al. Plasma concentration of C-reactive protein and risk of ischemic stroke and transient ischemic attack: the Framingham study. Stroke. 2001;32:2575–2579. doi:10.1161/hs1101.098151
   PubMed Web of Science ®Google Scholar
• Azur MJ, Stuart EA, Frangakis C, Leaf PJ. Multiple imputation by chained equations: what is it and how does it work? Int J Methods Psychiatr Res. 2011;20:40–49. doi:10.1002/mpr.329
   PubMed Web of Science ®Google Scholar
• Ashburner M, Ball CA, Blake JA, et al. Gene ontology: tool for the unification of biology. The Gene Ontology Consortium. Nat Genet. 2000;25:25–29. doi:10.1038/75556
   PubMed Web of Science ®Google Scholar
• Carbon S, Ireland A, Mungall CJ, et al. AmiGO: online access to ontology and annotation data. Bioinformatics. 2009;25:288–289. doi:10.1093/bioinformatics/btn615
   PubMed Web of Science ®Google Scholar
• Gene Ontology C, Douglass E, Good BM. The Gene Ontology resource: enriching a GOld mine. Nucleic Acids Res. 2021;49:D325–D334. doi:10.1093/nar/gkaa1113
   PubMed Web of Science ®Google Scholar
• Yin X, Subramanian S, Willinger CM, et al. Metabolite signatures of metabolic risk factors and their longitudinal changes. J Clin Endocrinol Metab. 2016;101:1779–1789. doi:10.1210/jc.2015-2555
   PubMed Web of Science ®Google Scholar
• Subramanian A, Tamayo P, Mootha VK, et al. Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. Proc Natl Acad Sci U S A. 2005;102:15545–15550. doi:10.1073/pnas.0506580102
   PubMed Web of Science ®Google Scholar
• Mootha VK, Lindgren CM, Eriksson K-F, et al. PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes. Nat Genet. 2003;34:267–273. doi:10.1038/ng1180
   PubMed Web of Science ®Google Scholar
• Olafsdottir IS, Gíslason T, Thjódleifsson B, et al. Gender differences in the association between C-reactive protein, lung function impairment, and COPD. Int J Chron Obstruct Pulmon Dis. 2007;2:635–642.
   PubMedGoogle Scholar
• Danesh J, Wheeler JG, Hirschfield GM, et al. C-reactive protein and other circulating markers of inflammation in the prediction of coronary heart disease. N Engl J Med. 2004;350:1387–1397. doi:10.1056/NEJMoa032804
   PubMed Web of Science ®Google Scholar
• Yeo ES, Hwang J-Y, Park JE, et al. Tumor necrosis factor (TNF-alpha) and C-reactive protein (CRP) are positively associated with the risk of chronic kidney disease in patients with type 2 diabetes. Yonsei Med J. 2010;51:519. doi:10.3349/ymj.2010.51.4.519
   PubMed Web of Science ®Google Scholar
• Ahmad T, Pencina MJ, Schulte PJ, et al. Clinical implications of chronic heart failure phenotypes defined by cluster analysis. J Am Coll Cardiol. 2014;64:1765–1774. doi:10.1016/j.jacc.2014.07.979
   PubMed Web of Science ®Google Scholar
• Ho JE, Lyass A, Lee DS, et al. Predictors of new-onset heart failure: differences in preserved versus reduced ejection fraction. Circ Heart Fail. 2013;6:279–286. doi:10.1161/CIRCHEARTFAILURE.112.972828
   PubMed Web of Science ®Google Scholar
• de Boer RA, Nayor M, deFilippi CR, et al. Association of cardiovascular biomarkers with incident heart failure with preserved and reduced ejection fraction. JAMA Cardiol. 2018;3:215. doi:10.1001/jamacardio.2017.4987
   PubMed Web of Science ®Google Scholar
• Tromp J, Westenbrink BD, Ouwerkerk W, et al. Identifying pathophysiological mechanisms in heart failure with reduced versus preserved ejection fraction. J Am Coll Cardiol. 2018;72:1081–1090. doi:10.1016/j.jacc.2018.06.050
   PubMed Web of Science ®Google Scholar
• Albar Z, Albakri M, Hajjari J, et al. Inflammatory markers and risk of heart failure with reduced to preserved ejection fraction. Am J Cardiol. 2022;167:68–75. doi:10.1016/j.amjcard.2021.11.045
   PubMed Web of Science ®Google Scholar