Lipidomics Changes in a Murine Model of Neuropsychiatric Lupus

References

• Carrión-Barberà I, Salman-Monte TC, Vílchez-Oya F, Monfort J. Neuropsychiatric involvement in systemic lupus erythematosus: a review. Autoimmun Rev. 2021;20(4):102780. doi:10.1016/j.autrev.2021.102780
   PubMed Web of Science ®Google Scholar
• Zhang L, Fu T, Yin R, Zhang Q, Shen B. Prevalence of depression and anxiety in systemic lupus erythematosus: a systematic review and meta-analysis. BMC Psychiatry. 2017;17(1):70. doi:10.1186/s12888-017-1234-1
   PubMedGoogle Scholar
• Bai R, Liu S, Zhao Y, et al. Depressive and anxiety disorders in systemic lupus erythematosus patients without major neuropsychiatric manifestations. J Immunol Res. 2016;2016:2829018. doi:10.1155/2016/2829018
   PubMed Web of Science ®Google Scholar
• Mackay M, Tang CC, Volpe BT, et al. Brain metabolism and autoantibody titres predict functional impairment in systemic lupus erythematosus. Lupus Sci Med. 2015;2(1):e000074. doi:10.1136/lupus-2014-000074
   PubMedGoogle Scholar
• Wang Y, Guo F, Guo Y, et al. Untargeted lipidomics reveals specific lipid abnormalities in systemic lupus erythematosus. Clin Exp Rheumatol. 2022;40(5):1011–1018. doi:10.55563/clinexprheumatol/ye2ua5
   PubMed Web of Science ®Google Scholar
• Zhang T, Mohan C. Caution in studying and interpreting the lupus metabolome. Arthritis Res Ther. 2020;22(1):172. doi:10.1186/s13075-020-02264-2
   PubMed Web of Science ®Google Scholar
• Hu C, Du Y, Xu X, et al. Lipidomics revealed aberrant metabolism of lipids including FAHFAs in renal tissue in the progression of lupus nephritis in a murine model. Metabolites. 2021;11(3):142. doi:10.3390/metabo11030142
   PubMed Web of Science ®Google Scholar
• van Kruining D, Luo Q, van Echten-Deckert G, et al. Sphingolipids as prognostic biomarkers of neurodegeneration, neuroinflammation, and psychiatric diseases and their emerging role in lipidomic investigation methods. Adv Drug Deliv Rev. 2020;159:232–244. doi:10.1016/j.addr.2020.04.009
   PubMed Web of Science ®Google Scholar
• Zhang G, Meng Q, Blencowe M, Agrawal R, Gomez-Pinilla F, Yang X. Multi-tissue multi-omics nutrigenomics indicates context-specific effects of docosahexaenoic acid on rat brain. Mol Nutr Food Res. 2020;64(23):e2000788. doi:10.1002/mnfr.202000788
   Web of Science ®Google Scholar
• Ying Z, Byun HR, Meng Q, et al. Biglycan gene connects metabolic dysfunction with brain disorder. Biochim Biophys Acta Mol Basis Dis. 2018;1864(12):3679–3687.
   PubMed Web of Science ®Google Scholar
• Geng C, Qiao Y, Guo Y, et al. Integrated metabolomics and lipidomics profiling of hippocampus reveal metabolite biomarkers in a rat model of chronic unpredictable mild stress-induced depression. Ann Transl Med. 2019;7(23):781. doi:10.21037/atm.2019.11.21
   PubMed Web of Science ®Google Scholar
• Gulinello M, Putterman C. The MRL/lpr mouse strain as a model for neuropsychiatric systemic lupus erythematosus. J Biomed Biotechnol. 2011;2011:207504. doi:10.1155/2011/207504
   PubMedGoogle Scholar
• Ballok DA. Neuroimmunopathology in a murine model of neuropsychiatric lupus. Brain Res Rev. 2007;54(1):67–79. doi:10.1016/j.brainresrev.2006.12.003
   PubMedGoogle Scholar
• Gao HX, Campbell SR, Cui MH, et al. Depression is an early disease manifestation in lupus-prone MRL/lpr mice. J Neuroimmunol. 2009;207(1–2):45–56. doi:10.1016/j.jneuroim.2008.11.009
   PubMed Web of Science ®Google Scholar
• Zhang F, Zhou Y, Chen H, et al. Curcumin alleviates DSS-induced anxiety-like behaviors via the microbial-brain-gut axis. Oxid Med Cell Longev. 2022;2022:6244757. doi:10.1155/2022/6244757
   PubMed Web of Science ®Google Scholar
• Fraga CG, Clowers BH, Moore RJ, Zink EM. Signature-discovery approach for sample matching of a nerve-agent precursor using liquid chromatography-mass spectrometry, XCMS, and chemometrics. Anal Chem. 2010;82(10):4165–4173. doi:10.1021/ac1003568
   PubMed Web of Science ®Google Scholar
• Govoni M, Bortoluzzi A, Padovan M, et al. The diagnosis and clinical management of the neuropsychiatric manifestations of lupus. J Autoimmun. 2016;74:41–72. doi:10.1016/j.jaut.2016.06.013
   PubMed Web of Science ®Google Scholar
• Liao J, Kang J, Li F, et al. A cross-sectional study on the association of anxiety and depression with the disease activity of systemic lupus erythematosus. BMC Psychiatry. 2022;22(1):591. doi:10.1186/s12888-022-04236-z
   PubMed Web of Science ®Google Scholar
• Hu C, Zhang J, Hong S, et al. Oxidative stress-induced aberrant lipid metabolism is an important causal factor for dysfunction of immunocytes from patients with systemic lupus erythematosus. Free Radic Biol Med. 2021;163:210–219. doi:10.1016/j.freeradbiomed.2020.12.006
   PubMed Web of Science ®Google Scholar
• Sun W, Li P, Cai J, et al. Lipid metabolism: immune regulation and therapeutic prospectives in systemic lupus erythematosus. Front Immunol. 2022;13:860586. doi:10.3389/fimmu.2022.860586
   PubMed Web of Science ®Google Scholar
• Tian J, Huang T, Chang S, et al. Role of sphingosine-1-phosphate mediated signalling in systemic lupus erythematosus. Prostaglandins Other Lipid Mediat. 2021;156:106584. doi:10.1016/j.prostaglandins.2021.106584
   PubMed Web of Science ®Google Scholar
• Teng X, Brown J, Choi SC, Li W, Morel L. Metabolic determinants of lupus pathogenesis. Immunol Rev. 2020;295(1):167–186. doi:10.1111/imr.12847
   PubMed Web of Science ®Google Scholar
• Chi JM, Mackay M, Hoang A, et al. Alterations in blood-brain barrier permeability in patients with systemic lupus erythematosus. AJNR Am J Neuroradiol. 2019;40(3):470–477. doi:10.3174/ajnr.A5990
   PubMed Web of Science ®Google Scholar
• Hanly JG, Kozora E, Beyea SD, Birnbaum J. Review: nervous system disease in systemic lupus erythematosus: current status and future directions. Arthritis Rheumatol. 2019;71(1):33–42. doi:10.1002/art.40591
   PubMed Web of Science ®Google Scholar
• Jung J, Lee SM, Lee MJ, et al. Lipidomics reveals that acupuncture modulates the lipid metabolism and inflammatory interaction in a mouse model of depression. Brain Behav Immun. 2021;94:424–436. doi:10.1016/j.bbi.2021.02.003
   PubMed Web of Science ®Google Scholar
• Borsini A, Nicolaou A, Camacho-Muñoz D, et al. Omega-3 polyunsaturated fatty acids protect against inflammation through production of LOX and CYP450 lipid mediators: relevance for major depression and for human hippocampal neurogenesis. Mol Psychiatry. 2021;26(11):6773–6788. doi:10.1038/s41380-021-01160-8
   PubMed Web of Science ®Google Scholar
• Mondal A, Bose D, Saha P, et al. Lipocalin 2 induces neuroinflammation and blood-brain barrier dysfunction through liver-brain axis in murine model of nonalcoholic steatohepatitis. J Neuroinflammation. 2020;17(1):201. doi:10.1186/s12974-020-01876-4
   PubMed Web of Science ®Google Scholar
• Bozek K, Wei Y, Yan Z, et al. Organization and evolution of brain lipidome revealed by large-scale analysis of human, chimpanzee, macaque, and mouse tissues. Neuron. 2015;85(4):695–702. doi:10.1016/j.neuron.2015.01.003
   PubMed Web of Science ®Google Scholar
• Zheng P, Wu J, Zhang H, et al. The gut microbiome modulates gut-brain axis glycerophospholipid metabolism in a region-specific manner in a nonhuman primate model of depression. Mol Psychiatry. 2021;26(6):2380–2392. doi:10.1038/s41380-020-0744-2
   PubMed Web of Science ®Google Scholar
• Jia HM, Li Q, Zhou C, et al. Chronic unpredictive mild stress leads to altered hepatic metabolic profile and gene expression. Sci Rep. 2016;6:23441. doi:10.1038/srep23441
   PubMed Web of Science ®Google Scholar
• Zhang Y, Yuan S, Pu J, et al. Integrated metabolomics and proteomics analysis of hippocampus in a rat model of depression. Neuroscience. 2018;371:207–220. doi:10.1016/j.neuroscience.2017.12.001
   PubMed Web of Science ®Google Scholar
• Farooqui AA, Horrocks LA, Farooqui T. Interactions between neural membrane glycerophospholipid and sphingolipid mediators: a recipe for neural cell survival or suicide. J Neurosci Res. 2007;85(9):1834–1850. doi:10.1002/jnr.21268
   PubMed Web of Science ®Google Scholar
• Zhang Q, Li X, Yin X, et al. Metabolomic profiling reveals serum L-pyroglutamic acid as a potential diagnostic biomarker for systemic lupus erythematosus. Rheumatology. 2021;60(2):598–606. doi:10.1093/rheumatology/keaa126
   PubMed Web of Science ®Google Scholar
• Gulinello M, Wen J, Putterman C. Neuropsychiatric symptoms in lupus. Psychiatr Ann. 2012;42(9):322–328. doi:10.3928/00485713-20120906-05
   PubMed Web of Science ®Google Scholar
• Jeltsch-David H, Muller S. Neuropsychiatric systemic lupus erythematosus and cognitive dysfunction: the MRL-lpr mouse strain as a model. Autoimmun Rev. 2014;13(9):963–973. doi:10.1016/j.autrev.2014.08.015
   PubMed Web of Science ®Google Scholar