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ORIGINAL RESEARCH

Periodic Mechanical Stress Inhibits the Development of Osteoarthritis via Regulating ATF3-Akt Axis

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Pages 5613-5628 | Received 25 May 2023, Accepted 25 Oct 2023, Published online: 27 Nov 2023

References

  • Tang X, Wang S, Zhan S, et al. The prevalence of symptomatic knee osteoarthritis in China: results from the China Health and Retirement Longitudinal Study. Arthritis Rheumatol. 2016;68(3):648–653. doi:10.1002/art.39465
  • Global Burden of Disease Study C. Global, regional, and national incidence, prevalence, and years lived with disability for 301 acute and chronic diseases and injuries in 188 countries, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet. 2015;386(9995):743–800.
  • Jordan JM, Helmick CG, Renner JB, et al. Prevalence of knee symptoms and radiographic and symptomatic knee osteoarthritis in African Americans and Caucasians: the Johnston County Osteoarthritis Project. J Rheumatol. 2007;34(1):172–180.
  • Katz JN, Arant KR, Loeser RF. Diagnosis and treatment of hip and knee osteoarthritis: a review. JAMA. 2021;325(6):568–578. doi:10.1001/jama.2020.22171
  • Lespasio MJ, Piuzzi NS, Husni ME, Muschler GF, Guarino A, Mont MA. Knee osteoarthritis: a primer. Perm J. 2017;21(4):16–183. doi:10.7812/TPP/16-183
  • Abramson SB, Attur M, Yazici Y. Prospects for disease modification in osteoarthritis. Nat Clin Pract Rheumatol. 2006;2(6):304–312. doi:10.1038/ncprheum0193
  • Poole AR. Osteoarthritis as a whole joint disease. HSS J. 2012;8(1):4–6. doi:10.1007/s11420-011-9248-6
  • Favero M, El-Hadi H, Belluzzi E, et al. Infrapatellar fat pad features in osteoarthritis: a histopathological and molecular study. Rheumatology. 2017;56(10):1784–1793. doi:10.1093/rheumatology/kex287
  • Glyn-Jones S, Palmer AJ, Agricola R, et al. Osteoarthritis. Lancet. 2015;386(9991):376–387. doi:10.1016/S0140-6736(14)60802-3
  • Sharma L, Kapoor D, Issa S. Epidemiology of osteoarthritis: an update. Curr Opin Rheumatol. 2006;18(2):147–156. doi:10.1097/01.bor.0000209426.84775.f8
  • Jiang W, Chen H, Lin Y, et al. Mechanical stress abnormalities promote chondrocyte senescence - The pathogenesis of knee osteoarthritis. Biomed Pharmacother. 2023;167:115552. doi:10.1016/j.biopha.2023.115552
  • Fang T, Zhou X, Jin M, Nie J, Li X. Molecular mechanisms of mechanical load-induced osteoarthritis. Int Orthop. 2021;45(5):1125–1136. doi:10.1007/s00264-021-04938-1
  • Zeng C, Wei J, Persson MSM, et al. Relative efficacy and safety of topical non-steroidal anti-inflammatory drugs for osteoarthritis: a systematic review and network meta-analysis of randomised controlled trials and observational studies. Br J Sports Med. 2018;52(10):642–650. doi:10.1136/bjsports-2017-098043
  • Ding C. Do NSAIDs affect the progression of osteoarthritis? Inflammation. 2002;26(3):139–142. doi:10.1023/A:1015504632021
  • Martel-Pelletier J, Boileau C, Pelletier JP, Roughley PJ. Cartilage in normal and osteoarthritis conditions. Best Pract Res Clin Rheumatol. 2008;22(2):351–384. doi:10.1016/j.berh.2008.02.001
  • Lian LP, Xi XY. Long non-coding RNA XIST protects chondrocytes ATDC5 and CHON-001 from IL-1beta-induced injury via regulating miR-653-5p/SIRT1 axis. J Biol Regul Homeost Agents. 2020;34(2):379–391. doi:10.23812/19-549-A-65
  • Uzieliene I, Bironaite D, Bernotas P, Sobolev A, Bernotiene E. Mechanotransducive biomimetic systems for chondrogenic differentiation in vitro. Int J Mol Sci. 2021;22(18). doi:10.3390/ijms22189690
  • Kurz B, Lemke AK, Fay J, Pufe T, Grodzinsky AJ, Schünke M. Pathomechanisms of cartilage destruction by mechanical injury. Ann Anat. 2005;187(5–6):473–485. doi:10.1016/j.aanat.2005.07.003
  • Kiviranta I, Tammi M, Jurvelin J, Säämänen AM, Helminen HJ. Moderate running exercise augments glycosaminoglycans and thickness of articular cartilage in the knee joint of young beagle dogs. J Orthop Res. 1988;6(2):188–195. doi:10.1002/jor.1100060205
  • Fitzgerald JB, Jin M, Grodzinsky AJ. Shear and compression differentially regulate clusters of functionally related temporal transcription patterns in cartilage tissue. J Biol Chem. 2006;281(34):24095–24103. doi:10.1074/jbc.M510858200
  • Liang W, Zhu C, Liu F, et al. Integrin beta1 gene therapy enhances in vitro creation of tissue-engineered cartilage under periodic mechanical stress. Cell Physiol Biochem. 2015;37(4):1301–1314. doi:10.1159/000430253
  • Liang W, Li Z, Wang Z, et al. Periodic mechanical stress INDUCES chondrocyte proliferation and matrix synthesis via CaMKII-mediated Pyk2 signaling. Cell Physiol Biochem. 2017;42(1):383–396. doi:10.1159/000477483
  • Ren K, Tang J, Jiang X, et al. Periodic mechanical stress stimulates Cav-1-dependent IGF-1R mitogenic signals in rat chondrocytes through ERK1/2. Cell Physiol Biochem. 2018;48(4):1652–1663. doi:10.1159/000492288
  • Ren K, Tang J, Jiang X, et al. Periodic mechanical stress stimulates GIT1-dependent mitogenic signals in rat chondrocytes through ERK1/2 activity. Cell Physiol Biochem. 2018;50(3):1015–1028. doi:10.1159/000494513
  • van Valburg AA, van Roermund PM, Lammens J, et al. Can Ilizarov joint distraction delay the need for an arthrodesis of the ankle? A preliminary report. J Bone Joint Surg Br. 1995;77(5):720–725. doi:10.1302/0301-620X.77B5.7559696
  • Gao G, Li H, Huang Y, et al. Periodic mechanical stress induces extracellular matrix expression and migration of rat nucleus pulposus cells through Src-GIT1-ERK1/2 signaling pathway. Cell Physiol Biochem. 2018;50(4):1510–1521. doi:10.1159/000494650
  • Hai T, Wolfgang CD, Marsee DK, Allen AE, Sivaprasad U. ATF3 and stress responses. Gene Expr. 1999;7(4–6):321–335.
  • Boespflug ND, Kumar S, McAlees JW, et al. ATF3 is a novel regulator of mouse neutrophil migration. Blood. 2014;123(13):2084–2093. doi:10.1182/blood-2013-06-510909
  • Zhou H, Guo H, Zong J, et al. ATF3 regulates multiple targets and may play a dual role in cardiac hypertrophy and injury. Int J Cardiol. 2014;174(3):838–839. doi:10.1016/j.ijcard.2014.04.160
  • Wu J, Huang Y, Zhou X, et al. ATF3 and its emerging role in atherosclerosis: a narrative review. Cardiovasc Diagn Ther. 2022;12(6):926–942. doi:10.21037/cdt-22-206
  • Fu D, Wang C, Yu L, Yu R. Induction of ferroptosis by ATF3 elevation alleviates cisplatin resistance in gastric cancer by restraining Nrf2/Keap1/xCT signaling. Cell Mol Biol Lett. 2021;26(1):26. doi:10.1186/s11658-021-00271-y
  • Di Marcantonio D, Martinez E, Kanefsky JS, et al. ATF3 coordinates serine and nucleotide metabolism to drive cell cycle progression in acute myeloid leukemia. Mol Cell. 2021;81(13):2752–2764 e2756. doi:10.3389/fcell.2021.618987
  • Huo S, Wang Q, Shi W, et al. ATF3/SPI1/SLC31A1 signaling promotes cuproptosis induced by advanced glycosylation end products in diabetic myocardial injury. Int J Mol Sci. 2023;24(2):1667. doi:10.3390/ijms24021667
  • Wu X, Qiu F, Jin X, Zhou J, Zang W. ATF3: a novel biomarker for the diagnosis of acute kidney injury after cardiac surgery. Ann Transl Med. 2021;9(22):1655. doi:10.21037/atm-21-5231
  • Iezaki T, Ozaki K, Fukasawa K, et al. ATF3 deficiency in chondrocytes alleviates osteoarthritis development. J Pathol. 2016;239(4):426–437. doi:10.1002/path.4739
  • Li X, Li Y, Yang X, et al. PR11-364P22.2/ATF3 protein interaction mediates IL-1beta-induced catabolic effects in cartilage tissue and chondrocytes. J Cell Mol Med. 2021;25(13):6188–6202. doi:10.1111/jcmm.16561
  • Song F, Wang Y, Jiang D, et al. Cyclic compressive stress regulates apoptosis in rat osteoblasts: involvement of PI3K/Akt and JNK MAPK signaling pathways. PLoS One. 2016;11(11):e0165845. doi:10.1371/journal.pone.0165845
  • Shen L, Zhou K, Liu H, et al. Prediction of mechanosensitive genes in vascular endothelial cells under high wall shear stress. Front Genet. 2021;12:796812. doi:10.3389/fgene.2021.796812
  • Chang HW, Sudirman S, Yen YW, Mao CF, Ong AD, Kong ZL. Blue Mussel (Mytilus edulis) water extract ameliorates inflammatory responses and oxidative stress on osteoarthritis in obese rats. J Pain Res. 2020;13:1109–1119. doi:10.2147/JPR.S244372
  • Wang BW, Jiang Y, Yao ZL, Chen PS, Yu B, Wang SN. Aucubin protects chondrocytes against il-1beta-induced apoptosis in vitro and inhibits osteoarthritis in mice model. Drug Des Devel Ther. 2019;13:3529–3538. doi:10.2147/DDDT.S210220
  • Fei J, Liang B, Jiang C, Ni H, Wang L. Luteolin inhibits IL-1beta-induced inflammation in rat chondrocytes and attenuates osteoarthritis progression in a rat model. Biomed Pharmacother. 2019;109:1586–1592. doi:10.1016/j.biopha.2018.09.161
  • Yu D, Liu F, Liu M, et al. The inhibition of subchondral bone lesions significantly reversed the weight-bearing deficit and the overexpression of CGRP in DRG neurons, GFAP and Iba-1 in the spinal dorsal horn in the monosodium iodoacetate induced model of osteoarthritis pain. PLoS One. 2013;8(10):e77824.
  • Huang Y, Wang L, Jia XX, Lin XX, Zhang WX. Vitamin D alleviates airway remodeling in asthma by down-regulating the activity of Wnt/beta-catenin signaling pathway. Int Immunopharmacol. 2019;68:88–94. doi:10.1016/j.intimp.2018.12.061
  • Gu XD, Wei L, Li PC, et al. Adenovirus-mediated transduction with Histone Deacetylase 4 ameliorates disease progression in an osteoarthritis rat model. Int Immunopharmacol. 2019;75:105752. doi:10.1016/j.intimp.2019.105752
  • Li X, Ellman M, Muddasani P, et al. Prostaglandin E2 and its cognate EP receptors control human adult articular cartilage homeostasis and are linked to the pathophysiology of osteoarthritis. Arthritis Rheum. 2009;60(2):513–523. doi:10.1002/art.24258
  • Abramoff B, Caldera FE. Osteoarthritis: pathology, Diagnosis, and Treatment Options. Med Clin North Am. 2020;104(2):293–311. doi:10.1016/j.mcna.2019.10.007
  • Ouyang Z, Dong L, Yao F, et al. Cartilage-related collagens in osteoarthritis and rheumatoid arthritis: from pathogenesis to therapeutics. Int J Mol Sci. 2023;24(12):9841. doi:10.3390/ijms24129841
  • Gao S, Gao L, Wang S, et al. ATF3 suppresses growth and metastasis of clear cell renal cell carcinoma by deactivating EGFR/AKT/GSK3beta/beta-catenin signaling pathway. Front Cell Dev Biol. 2021;9:618987.
  • Zu T, Wang D, Xu S, et al. ATF-3 expression inhibits melanoma growth by downregulating ERK and AKT pathways. Lab Invest. 2021;101(5):636–647. doi:10.1038/s41374-020-00516-y
  • Shi Q, Hu B, Yang C, et al. ATF3 inhibits arsenic-induced malignant transformation of human bronchial epithelial cells by attenuating inflammation. Toxicology. 2021;460:152890. doi:10.1016/j.tox.2021.152890
  • Jess R, Ling T, Xiong Y, Wright CJ, Zhao F. Mechanical environment for in vitro cartilage tissue engineering assisted by in silico models. Biomater Transl. 2023;4(1):18–26. doi:10.12336/biomatertransl.2023.01.004
  • Logerstedt DS, Ebert JR, MacLeod TD, Heiderscheit BC, Gabbett TJ, Eckenrode BJ. Effects of and Response to Mechanical Loading on the Knee. Sports Med. 2022;52(2):201–235. doi:10.1007/s40279-021-01579-7
  • Fu S, Thompson CL, Ali A, et al. Mechanical loading inhibits cartilage inflammatory signalling via an HDAC6 and IFT-dependent mechanism regulating primary cilia elongation. Osteoarthritis Cartilage. 2019;27(7):1064–1074. doi:10.1016/j.joca.2019.03.003
  • Molnar V, Matisic V, Kodvanj I, et al. Cytokines and chemokines involved in osteoarthritis pathogenesis. Int J Mol Sci. 2021;22(17):9208. doi:10.3390/ijms22179208
  • Hortobagyi D, Grossmann T, Tschernitz M, et al. In vitro mechanical vibration down-regulates pro-inflammatory and pro-fibrotic signaling in human vocal fold fibroblasts. PLoS One. 2020;15(11):e0241901. doi:10.1371/journal.pone.0241901