Single-Cell RNA Sequencing Reveals Roles of Fibroblasts During Intestinal Injury and Repair in Rats with Severe Acute Pancreatitis

References

• Boxhoorn L, Voermans RP, Bouwense SA, et al. Acute pancreatitis. Lancet. 2020;396(10252):726–734. doi:10.1016/S0140-6736(20)31310-6
   PubMed Web of Science ®Google Scholar
• Gardner TB. Acute Pancreatitis. Ann Intern Med. 2021;174(2):ITC17–ITC32. doi:10.7326/AITC202102160
   PubMed Web of Science ®Google Scholar
• Banerjee A, McKinley ET, von Moltke J, et al. Interpreting heterogeneity in intestinal tuft cell structure and function. J Clin Invest. 2018;128(5):1711–1719. doi:10.1172/JCI120330
   PubMed Web of Science ®Google Scholar
• Viola MF, Boeckxstaens G. Niche-specific functional heterogeneity of intestinal resident macrophages. Gut. 2021;70(7):1383–1395. doi:10.1136/gutjnl-2020-323121
   PubMed Web of Science ®Google Scholar
• Wang J, Xu H, Chen T, et al. Effect of monoacylglycerol lipase inhibition on intestinal permeability of rats with severe acute pancreatitis. Front Pharmacol. 2022;13:869482. doi:10.3389/fphar.2022.869482
   PubMed Web of Science ®Google Scholar
• James KR, Elmentaite R, Teichmann SA, et al. Redefining intestinal immunity with single-cell transcriptomics. Mucosal Immunol. 2022;15(4):531–541. doi:10.1038/s41385-021-00470-y
   PubMed Web of Science ®Google Scholar
• Yan H, Ye Y, Zhao H, et al. Single-cell RNA sequencing for analyzing the intestinal tract in healthy and diseased individuals. Front Cell Dev Biol. 2022;10:915654. doi:10.3389/fcell.2022.915654
   PubMed Web of Science ®Google Scholar
• Butler A, Hoffman P, Smibert P, et al. Integrating single-cell transcriptomic data across different conditions, technologies, and species. Nat Biotechnol. 2018;36(5):411–420. doi:10.1038/nbt.4096
   PubMed Web of Science ®Google Scholar
• Ianevski A, Giri AK, Aittokallio T. Fully-automated and ultra-fast cell-type identification using specific marker combinations from single-cell transcriptomic data. Nat Commun. 2022;13(1):1246. doi:10.1038/s41467-022-28803-w
   PubMed Web of Science ®Google Scholar
• Wang Y, Song W, Wang J, et al. Single-cell transcriptome analysis reveals differential nutrient absorption functions in human intestine. J Exp Med. 2020;217(2):e20191130. doi:10.1084/jem.20191130
   PubMed Web of Science ®Google Scholar
• Li H, Wang X, Wang Y, et al. Cross-species single-cell transcriptomic analysis reveals divergence of cell composition and functions in mammalian ileum epithelium. Cell Regen. 2022;11(1):19. doi:10.1186/s13619-022-00118-7
   PubMedGoogle Scholar
• Gerstberger S, Hafner M, Tuschl T. A census of human RNA-binding proteins. Nat Rev Genet. 2014;15(12):829–845. doi:10.1038/nrg3813
   PubMed Web of Science ®Google Scholar
• Castello A, Fischer B, Frese CK, et al. Comprehensive identification of RNA-binding domains in human cells. Mol Cell. 2016;63(4):696–710. doi:10.1016/j.molcel.2016.06.029
   PubMed Web of Science ®Google Scholar
• Hentze MW, Castello A, Schwarzl T, et al. A brave new world of RNA-binding proteins. Nat Rev Mol Cell Biol. 2018;19(5):327–341. doi:10.1038/nrm.2017.130
   PubMed Web of Science ®Google Scholar
• Ali A, Shafarin J, Abu Jabal R, et al. Ferritin heavy chain (FTH1) exerts significant antigrowth effects in breast cancer cells by inhibiting the expression of c-MYC. FEBS Open Bio. 2021;11(11):3101–3114. doi:10.1002/2211-5463.13303
   PubMed Web of Science ®Google Scholar
• Xie C, Mao X, Huang J, et al. KOBAS 2.0: a web server for annotation and identification of enriched pathways and diseases. Nucleic Acids Res. 2011;39(Web Server issue):W316–W322. doi:10.1093/nar/gkr483
   PubMed Web of Science ®Google Scholar
• Jin S, Guerrero-Juarez CF, Zhang L, et al. Inference and analysis of cell-cell communication using CellChat. Nat Commun. 2021;12(1):1088. doi:10.1038/s41467-021-21246-9
   PubMed Web of Science ®Google Scholar
• Phipson B, Sim CB, Porrello ER, et al. propeller: testing for differences in cell type proportions in single cell data. Bioinformatics. 2022;38(20):4720–4726. doi:10.1093/bioinformatics/btac582
   PubMed Web of Science ®Google Scholar
• Ge P, Luo Y, Okoye CS, et al. Intestinal barrier damage, systemic inflammatory response syndrome, and acute lung injury: a troublesome trio for acute pancreatitis. Biomed Pharmacother. 2020;132:110770. doi:10.1016/j.biopha.2020.110770
   PubMed Web of Science ®Google Scholar
• Liu D, Wen L, Wang Z, et al. The mechanism of lung and intestinal injury in acute pancreatitis: a review. Front Med. 2022;9:904078. doi:10.3389/fmed.2022.904078
   Web of Science ®Google Scholar
• Cray P, Sheahan BJ, Dekaney CM. Secretory sorcery: Paneth cell control of intestinal repair and homeostasis. Cell Mol Gastroenterol Hepatol. 2021;12(4):1239–1250. doi:10.1016/j.jcmgh.2021.06.006
   PubMed Web of Science ®Google Scholar
• Dang H, Harryvan TJ, Hawinkels LJAC. Fibroblast subsets in intestinal homeostasis, carcinogenesis, tumor progression, and metastasis. Cancers. 2021;13(2):183. doi:10.3390/cancers13020183
   PubMed Web of Science ®Google Scholar
• Moreira Lopes TC, Mosser DM, Gonçalves R. Macrophage polarization in intestinal inflammation and gut homeostasis. Inflamm Res. 2020;69(12):1163–1172. doi:10.1007/s00011-020-01398-y
   PubMed Web of Science ®Google Scholar
• Flemming S, Luissint AC, Kusters DHM, et al. Desmocollin-2 promotes intestinal mucosal repair by controlling integrin-dependent cell adhesion and migration. Mol Biol Cell. 2020;31(6):407–418. doi:10.1091/mbc.E19-12-0692
   PubMed Web of Science ®Google Scholar
• Quiros M. Therapeutic opportunities for repair GPCRs during intestinal mucosal wound healing. Trends Mol Med. 2020;26(11):971–974. doi:10.1016/j.molmed.2020.08.011
   PubMed Web of Science ®Google Scholar
• Sommer K, Wiendl M, Müller TM, et al. Intestinal mucosal wound healing and barrier integrity in IBD-crosstalk and trafficking of cellular players. Front Med. 2021;8:643973. doi:10.3389/fmed.2021.643973
   PubMed Web of Science ®Google Scholar
• Al-Ghadban S, Kaissi S, Homaidan FR, et al. Cross-talk between intestinal epithelial cells and immune cells in inflammatory bowel disease. Sci Rep. 2016;6(1):29783. doi:10.1038/srep29783
   PubMedGoogle Scholar
• Gaudino SJ, Kumar P. Cross-talk between antigen presenting cells and T cells impacts intestinal homeostasis, bacterial infections, and tumorigenesis. Front Immunol. 2019;10:360. doi:10.3389/fimmu.2019.00360
   PubMed Web of Science ®Google Scholar
• Shen Q, Huang Z, Yao J, et al. Extracellular vesicles-mediated interaction within intestinal microenvironment in inflammatory bowel disease. J Adv Res. 2021;37:221–233. doi:10.1016/j.jare.2021.07.002
   PubMed Web of Science ®Google Scholar
• Schulz MC, Gekle M, Schwerdt G. Epithelial-fibroblast cross talk aggravates the impact of the nephrotoxin ochratoxin A. Biochim Biophys Acta Mol Cell Res. 2019;1866(12):118528. doi:10.1016/j.bbamcr.2019.118528
   PubMed Web of Science ®Google Scholar
• Amiri N, Golin AP, Jalili RB, et al. Roles of cutaneous cell-cell communication in wound healing outcome: an emphasis on keratinocyte-fibroblast crosstalk. Exp Dermatol. 2022;31(4):475–484. doi:10.1111/exd.14516
   PubMed Web of Science ®Google Scholar
• Gardiner JC, Cukierman E. Meaningful connections: interrogating the role of physical fibroblast cell-cell communication in cancer. Adv Cancer Res. 2022;154:141–168. doi:10.1016/bs.acr.2022.01.004
   PubMedGoogle Scholar
• Hung CF, Rohani MG, Lee SS, et al. Role of IGF-1 pathway in lung fibroblast activation. Respir Res. 2013;14(1):102. doi:10.1186/1465-9921-14-102
   PubMedGoogle Scholar
• Tamilzhalagan S, Rathinam D, Ganesan K. Amplified 7q21-22 gene MCM7 and its intronic miR-25 suppress COL1A2 associated genes to sustain intestinal gastric cancer features. Mol Carcinog. 2017;56(6):1590–1602. doi:10.1002/mc.22614
   PubMed Web of Science ®Google Scholar