The Recombinant Profilin from Free-Living Amoebae Induced Allergic Immune Responses via TLR2

References

• Janeway CA Jr, Medzhitov R. Innate immune recognition. Annu Rev Immunol. 2002;20:197–216.
   PubMed Web of Science ®Google Scholar
• Chaturvedi A, Pierce SK. How location governs toll-like receptor signaling. Traffic. 2009;10(6):621–628.
   PubMed Web of Science ®Google Scholar
• Hacker H, Mischak H, Miethke T, et al. CpG-DNA-specific activation of antigen-presenting cells requires stress kinase activity and is preceded by non-specific endocytosis and endosomal maturation. EMBO J. 1998;17(21):6230–6240.
   PubMed Web of Science ®Google Scholar
• Ahmad-Nejad P, Hacker H, Rutz M, Bauer S, Vabulas RM, Wagner H. Bacterial CpG-DNA and lipopolysaccharides activate Toll-like receptors at distinct cellular compartments. Eur J Immunol. 2002;32(7):1958–1968.
   PubMed Web of Science ®Google Scholar
• Leonard JN, Ghirlando R, Askins J, et al. The TLR3 signaling complex forms by cooperative receptor dimerization. Proc Natl Acad Sci U S A. 2008;105(1):258–263.
   PubMed Web of Science ®Google Scholar
• Tan RS, Ho B, Leung BP, Ding JL. TLR cross-talk confers specificity to innate immunity. Int Rev Immunol. 2014;33(6):443–453.
   PubMed Web of Science ®Google Scholar
• Merad M, Sathe P, Helft J, Miller J, Mortha A. The dendritic cell lineage: ontogeny and function of dendritic cells and their subsets in the steady state and the inflamed setting. Annu Rev Immunol. 2013;31:563–604.
   PubMed Web of Science ®Google Scholar
• Hou B, Reizis B, DeFranco AL. Toll-like receptors activate innate and adaptive immunity by using dendritic cell-intrinsic and -extrinsic mechanisms. Immunity. 2008;29(2):272–282.
   PubMed Web of Science ®Google Scholar
• Ebihara N, Yamagami S, Chen L, et al. Expression and function of toll-like receptor-3 and −9 in human corneal myofibroblasts. Invest Ophthalmol Vis Sci. 2007;48(7):3069–3076.
   PubMed Web of Science ®Google Scholar
• Santone M, Aprea S, Wu TY, et al. A new TLR2 agonist promotes cross-presentation by mouse and human antigen presenting cells. Hum Vaccin Immunother. 2015;11(8):2038–2050.
   PubMed Web of Science ®Google Scholar
• Hemmi H, Akira S. TLR signalling and the function of dendritic cells. Chem Immunol Allergy. 2005;86:120–135.
   PubMedGoogle Scholar
• Fillatreau S, Manz RA. Tolls for B cells. Eur J Immunol. 2006;36(4):798–801.
   PubMed Web of Science ®Google Scholar
• Kapsenberg ML. Dendritic-cell control of pathogen-driven T-cell polarization. Nat Rev Immunol. 2003;3(12):984–993.
   PubMed Web of Science ®Google Scholar
• Wang X, Yuan T, Yuan J, et al. Expression of Toll-Like Receptor 2 by Dendritic Cells Is Essential for the DnaJ-DeltaA146Ply-Mediated Th1 Immune Response against Streptococcus pneumoniae. Infect Immun. 2018;86(3):67.
   Web of Science ®Google Scholar
• Gao Y, Xiao H, Wang Y, Xu F. Association of single-nucleotide polymorphisms in toll-like receptor 2 gene with asthma susceptibility: a meta-analysis. Medicine. 2017;96(20):e6822.
   PubMed Web of Science ®Google Scholar
• Zhao J, Shang H, Cao X, et al. Association of polymorphisms in TLR2 and TLR4 with asthma risk: an update meta-analysis. Medicine. 2017;96(35):e7909.
   PubMed Web of Science ®Google Scholar
• Kirtland ME, Tsitoura DC, Durham SR, Shamji MH. Toll-Like Receptor Agonists as Adjuvants for Allergen Immunotherapy. Front Immunol. 2020;11:599083.
   PubMed Web of Science ®Google Scholar
• Marciano-Cabral F, Cabral G. Acanthamoeba spp. as agents of disease in humans. Clin Microbiol Rev. 2003;16(2):273–307.
   PubMed Web of Science ®Google Scholar
• Kot K, Lanocha-Arendarczyk N, Kosik-Bogacka D. Immunopathogenicity of Acanthamoeba spp. in the Brain and Lungs. Int J Mol Sci. 2021;22(3).
   Web of Science ®Google Scholar
• Park MK, Cho MK, Kang SA, Park HK, Kim DH, Yu HS. Acanthamoeba protease activity promotes allergic airway inflammation via protease-activated receptor 2. PLoS One. 2014;9(3):e92726.
   PubMed Web of Science ®Google Scholar
• Park MK, Park HK, Yu HS. Toll-like receptor 2 mediates Acanthamoeba-induced allergic airway inflammatory response in mice. PLoS Negl Trop Dis. 2023;17(1):e0011085.
   PubMed Web of Science ®Google Scholar
• Park HK, Park MK, Kim KU, et al. Evaluation of allergic sensitivity to Acanthamoeba allergen in patients with chronic cough. Allergy Asthma Proc. 2016;37(2):141–147.
   PubMed Web of Science ®Google Scholar
• Song SM, Kang SA, Park HK, et al. Acanthamoeba profilin elicits allergic airway inflammation in mice. PLoS Negl Trop Dis. 2018;12(12):e0006979.
   PubMed Web of Science ®Google Scholar
• McKerrow JH, Sun E, Rosenthal PJ, Bouvier J. The proteases and pathogenicity of parasitic protozoa. Annu Rev Microbiol. 1993;47:821–853.
   PubMed Web of Science ®Google Scholar
• Mitro K, Bhagavathiammai A, Zhou OM, et al. Partial characterization of the proteolytic secretions of Acanthamoeba polyphaga. Exp Parasitol. 1994;78(4):377–385.
   PubMed Web of Science ®Google Scholar
• He YG, Niederkorn JY, McCulley JP, et al. In vivo and in vitro collagenolytic activity of Acanthamoeba castellanii. Invest Ophthalmol Vis Sci. 1990;31(11):2235–2240.
   PubMed Web of Science ®Google Scholar
• Khan NA, Jarroll EL, Panjwani N, Cao Z, Paget TA. Proteases as markers for differentiation of pathogenic and nonpathogenic species of Acanthamoeba. J Clin Microbiol. 2000;38(8):2858–2861.
   PubMed Web of Science ®Google Scholar
• Kaiser DA, Sato M, Ebert RF, Pollard TD. Purification and characterization of two isoforms of Acanthamoeba profilin. J Cell Biol. 1986;102(1):221–226.
   PubMed Web of Science ®Google Scholar
• Gunning PW, Ghoshdastider U, Whitaker S, Popp D, Robinson RC. The evolution of compositionally and functionally distinct actin filaments. J Cell Sci. 2015;128(11):2009–2019.
   PubMed Web of Science ®Google Scholar
• Scheurer S, Wangorsch A, Haustein D, Vieths S. Cloning of the minor allergen Api g 4 profilin from celery (Apium graveolens) and its cross-reactivity with birch pollen profilin Bet v 2. Clin Exp Allergy. 2000;30(7):962–971.
   PubMed Web of Science ®Google Scholar
• Rodriguez Del Rio P, Diaz-Perales A, Sanchez-Garcia S, et al. Profilin, a Change in the Paradigm. J Investig Allergol Clin Immunol. 2018;28(1):1–12.
   PubMed Web of Science ®Google Scholar
• Salazar F, Ghaemmaghami AM. Allergen recognition by innate immune cells: critical role of dendritic and epithelial cells. Front Immunol. 2013;4:356.
   PubMed Web of Science ®Google Scholar
• Wills-Karp M. Allergen-specific pattern recognition receptor pathways. Curr Opin Immunol. 2010;22(6):777–782.
   PubMed Web of Science ®Google Scholar
• Ma SQ, Wei HL, Zhang X. TLR2 regulates allergic airway inflammation through NF-kappaB and MAPK signaling pathways in asthmatic mice. Eur Rev Med Pharmacol Sci. 2018;22(10):3138–3146.
   PubMed Web of Science ®Google Scholar
• Heijink IH, Kuchibhotla VNS, Roffel MP, et al. Epithelial cell dysfunction, a major driver of asthma development. Allergy. 2020;75(8):1902–1917.
   PubMed Web of Science ®Google Scholar
• Chen K, Xiang Y, Yao X, et al. The active contribution of Toll-like receptors to allergic airway inflammation. Int Immunopharmacol. 2011;11(10):1391–1398.
   PubMed Web of Science ®Google Scholar
• Beutler B. Inferences, questions and possibilities in Toll-like receptor signalling. Nature. 2004;430(6996):257–263.
   PubMed Web of Science ®Google Scholar
• Redecke V, Hacker H, Datta SK, et al. Cutting edge: activation of Toll-like receptor 2 induces a Th2 immune response and promotes experimental asthma. J Iimmunol. 2004;172(5):2739–2743.
   PubMed Web of Science ®Google Scholar
• Patel M, Xu D, Kewin P, et al. TLR2 agonist ameliorates established allergic airway inflammation by promoting Th1 response and not via regulatory T cells. J Iimmunol. 2005;174(12):7558–7563.
   PubMed Web of Science ®Google Scholar
• Velasco G, Campo M, Manrique OJ, et al. Toll-like receptor 4 or 2 agonists decrease allergic inflammation. Am J Respir Cell Mol Biol. 2005;32(3):218–224.
   PubMed Web of Science ®Google Scholar
• Fang L, Shen Q, Wu H, et al. TLR2 favors OVA-induced allergic airway inflammation in mice through JNK signaling pathway with activation of autophagy. Life Sci. 2020;256:117896.
   PubMed Web of Science ®Google Scholar