111
Views
24
CrossRef citations to date
0
Altmetric
Original Research

Effects of exendin-4, a glucagon like peptide-1 receptor agonist, on neutrophil count and inflammatory cytokines in a rat model of endotoxemia

, , , &
Pages 129-135 | Published online: 24 Jul 2015

References

  • MartinGSManninoDMEatonSMossMThe epidemiology of sepsis in the United States from 1979 through 2000N Engl J Med2003348161546155412700374
  • AngusDCLinde-ZwirbleWTLidickerJClermontGCarcilloJPinskyMREpidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of careCrit Care Med20012971303131011445675
  • HotchkissRSMonneretGPayenDImmunosuppression in sepsis: a novel understanding of the disorder and a new therapeutic approachLancet Infect Dis201313326026823427891
  • SchulteWBernhagenJBucalaRCytokines in sepsis: potent immunoregulators and potential therapeutic targets – an updated viewMediators Inflamm2013201316597423853427
  • Van den BergheGWoutersPWeekersFIntensive insulin therapy in critically ill patientsN Engl J Med2001345191359136711794168
  • VlasselaersDMilantsIDesmetLIntensive insulin therapy for patients in paediatric intensive care: a prospective, randomized control studyLancet2009373966354755619176240
  • The NICE SUGAR Study investigatorsFinferSChittockDRIntensive versus conventional glucose control in critically ill patientsN Engl J Med2009360131283129719318384
  • BaggioLLDruckerDJBiology of Incretins: GLP-1 and GIPGastroenterology200713262131215717498508
  • ZanderMMadsbadSMadsenJLHolstJJEffect of 6-week course of glucagon-like peptide-1 on glycaemic control, insulin sensitivity, and beta-cell function in type 2 diabetes: a parallel-group studyLancet2002359930982483011897280
  • ShyangdanDSRoylePClarCSharmaPWaughNSnaithAGlucagon-like peptide analogues for type 2 diabetes mellitusCochrane Database Syst Rev201110CD00642321975753
  • KimWEganJMThe role of incretins in glucose homeostasis and diabetes treatmentPharmacol Rev200860447051219074620
  • LindMJendleJTorffvitOLagerIGlucagon-like peptide 1 (GLP-1) analogue combined with insulin reduces HbA1c and weight with low risk of hypoglycemia and high treatment satisfactionPrim Care Diabetes201261414622015237
  • BullockBPHellerRSHabenerJFTissue distribution of messenger ribonucleic acid encoding the rat glucagon-like peptide-1 receptorEndocrinology19961377296829788770921
  • DunphyJLTaylorRGFullerPJTissue distribution of rat glucagon receptor and GLP-1 receptor gene expressionMol Cell Endocrinol19981411–21791869723898
  • BenitoEBlazquezEBoschMAGlucagon-like peptide-1-(7–36)amide increases pulmonary surfactant secretion through a cyclic adenosine 3′5′-monophosphate-dependent protein kinase mechanism in rat type II pneumocytesEndocrinology19981395236323689564846
  • HuisamenBGenadeSLochnerASignaling pathways activated by glucagon-like peptide-1 (7–36) amide in the rat heart and their role in protection against ischemiaCardiovasc J Afr2008192778318516352
  • IwaiTItoSTanimitsuKUdagawaSOkaJGlucagon-like peptide-1 inhibits LPS induced IL-1beta production in cultured rat astrocytesNeurosci Res200655435236016720054
  • SonneDPEngstromTTreimanMProtective effects of GLP-1 analogues exendin-4 and GLP-1(9–36) amide against ischemia reperfusion injury in rat heartRegul Pept20081461–324324917976835
  • DokkenBBLa BonteLRDavis-GormanGTeacheyMKSeaverNMcDonaghPFGlucagon-like peptide-1 (GLP-1) immediately prior to reperfusion, decreases neutrophil activation and reduces myocardial Infarct size in rodentsHorm Metab Res201143530030521360419
  • KuSKHanMSParkEJNaDHBaeJSExendin-4 inhibits endothelial protein C receptor shedding in vitro and in vivoPharmacol Res201484182524769195
  • KissowHHartmannBHolstJJPoulsenSSGlucagon-like peptide-1 as a treatment for chemotherapy-induced mucositisGut201362121724173323086829
  • KoderaRShikataKKataokaHUGlucagon-like peptide-1 receptor agonist ameliorates renal injury through its anti-inflammatory action without lowering blood glucose level in a rat model of type 1 diabetesDiabetologia201154496597821253697
  • IwaiTSawabeTTanimitsuKSuzukiMSasaki-HamadaSOkaJGlucagon-like peptide-1 protects synaptic and learning functions from neuroinflammation in rodentsJ Neurosci Res201492444645424464856
  • ChaudhuriAGhanimHVoraMExenatide exerts a potent anti-inflammatory effectJ Clin Endocrinol Metab201297119820722013105
  • EngJKleinmanWASinghLSinghGRaufmanJPIsolation and characterization of exendin-4, an exendin-3 analogue, from Heloderma suspectum venomJ Biol Chem199226711740274051313797
  • GokeRFehmannHCLinnTExendin-4 is a high potency agonist, and truncated Exendin-(9–39)-amide an antagonist at the glucagon like peptide 1-(7–36)-amide receptor of insulin secreting β cellsJ Biol Chem19932682619650196558396143
  • BadiuDCPaunescuVAungurenciAPasaricaDProinflammatory cytokines in peritonitisJ Med Life20114215816221776298
  • KellumJAKongLFinkMPUnderstanding the inflammatory cytokine response in pneumonia and sepsis: results of the Genetic and Inflammatory Markers of Sepsis (GenIMS) StudyArch Intern Med2007167151655166317698689
  • No authors listedAmerican College of Chest Physicians/Society of Critical Care Medicine Consensus Conference: definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsisCrit Care Med19922068648741597042
  • MeierJJWeyheDMichaelyMIntravenous glucagon-like peptide 1 normalizes blood glucose after major surgery in patients with type 2 diabetesCrit Care Med200432384885115090972
  • CatonPWNavuniNKMurchOCorderREndotoxin induced hyperlactatemia and hypoglycemia is linked to decreased mitochondrial phosphoenolpyruvate carboxykinaseLife Sci20098421–2273874419268478
  • MalendowiczLKNowakKWPreproglucagon derived peptides and thyrotropin (TSH) secretion in the rat: robust and sustained lowering of blood TSH levels in exendin-4 injected animalsInt J Mol Med200210332733112165809