Low-Level Laser Therapy and Topical Medications for Treating Aphthous Ulcers: A Systematic Review

References

• Edgar NR, Saleh D, Miller RA. Recurrent aphthous stomatitis: a review. J Clin Aesthet Dermatol. 2017;10(3):26–36.
   PubMedGoogle Scholar
• Syed V. Comprehensive review on aphthous ulcers of oral cavity. Int J Med Health Res. 2017;3(5):1–3.
   Google Scholar
• Patil S, Reddy SN, Maheshwari S, Khandelwal S, Shruthi D, Doni B. Prevalence of recurrent aphthous ulceration in the Indian population. J Clin Exp Dent. 2014;6(1):e36–e40. doi:10.4317/jced.51227
   PubMedGoogle Scholar
• Andreas ANE-H, Christiana M, Marion P, Mohammed BA-N, Christos CZ. The treatment of chronic recurrent oral aphthous ulcers. Dtsch Arztebl Int. 2014;111(40):665–673.
   Web of Science ®Google Scholar
• Queiroz SIML, Silva MVAD, Medeiros AMC, Oliveira PT, Gurgel BCV, Silveira É. Recurrent aphthous ulceration: an epidemiological study of etiological factors, treatment and differential diagnosis. An Bras Dermatol. 2018;93(3):341–346. doi:10.1590/abd1806-4841.20186228
   Web of Science ®Google Scholar
• Tarakji B, Gazal G, Al-Maweri SA, Azzeghaiby SN, Alaizari N. Guideline for the diagnosis and treatment of recurrent aphthous stomatitis for dental practitioners. J Int Oral Health. 2015;7(5):74–80.
   PubMedGoogle Scholar
• Bankvall M, Sjöberg F, Gale G, Wold A, Jontell M, Östman S. The oral microbiota of patients with recurrent aphthous stomatitis. J Oral Microbiol. 2014;6:25739. doi:10.3402/jom.v6.25739
   PubMed Web of Science ®Google Scholar
• Zwiri AM. Anxiety, depression and quality of life among patients with recurrent aphthous ulcers. J Contemp Dent Pract. 2015;16(2):112–117. doi:10.5005/jp-journals-10024-1646
   PubMedGoogle Scholar
• Kürklü-Gürleyen E, Öğüt-Erişen M, Çakır O, Uysal Ö, Ak G. Quality of life in patients with recurrent aphthous stomatitis treated with a mucoadhesive patch containing citrus essential oil. Patient Prefer Adherence. 2016;10:967–973. doi:10.2147/PPA.S106530
   PubMed Web of Science ®Google Scholar
• Belenguer-Guallar I, Jiménez-Soriano Y, Claramunt-Lozano A. Treatment of recurrent aphthous stomatitis. A literature review. J Clin Exp Dent. 2014;6(2):e168–e174. doi:10.4317/jced.51401
   PubMedGoogle Scholar
• Tezel A, Kara C, Balkaya V, Orbak R. An evaluation of different treatments for recurrent aphthous stomatitis and patient perceptions: nd:YAG laser versus medication. Photomed Laser Surg. 2009;27(1):101–106. doi:10.1089/pho.2008.2274
   Web of Science ®Google Scholar
• Prasad RS, Pai A. Assessment of immediate pain relief with laser treatment in recurrent aphthous stomatitis. Oral Surg Oral Med Oral Pathol Oral Radiol. 2013;116(2):189–193. doi:10.1016/j.oooo.2013.02.011
   Web of Science ®Google Scholar
• Zand N, Ataie-Fashtami L, Djavid GE, et al. Relieving pain in minor aphthous stomatitis by a single session of non-thermal carbon dioxide laser irradiation. Lasers Med Sci. 2009;24(4):515–520. doi:10.1007/s10103-008-0555-1
   Web of Science ®Google Scholar
• Akerzoul N, Chbicheb S. Low laser therapy as an effective treatment of recurrent aphtous ulcers: a clinical case reporting two locations. Pan Afr Med J. 2018;30:205.
   Web of Science ®Google Scholar
• Anand V, Gulati M, Govila V, Anand B. Low level laser therapy in the treatment of aphthous ulcer. Indian J Dent Res. 2013;24(2):267–270. doi:10.4103/0970-9290.116691
   Google Scholar
• Vale FA, Moreira MS, Almeida FC, Ramalho KM. Low-level laser therapy in the treatment of recurrent aphthous ulcers: a systematic review. Sci World J. 2015;2015.
   Google Scholar
• Aggarwal H, Singh MP, Nahar P, Mathur H, Gv S. Efficacy of low-level laser therapy in treatment of recurrent aphthous ulcers - a sham controlled, split mouth follow up study. J Clin Diagn Res. 2014;8(2):218–221.
   Google Scholar
• Liberati A, Altman DG, Tetzlaff J, et al. The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration. PLoS Med. 2009;6(7):e1000100.
   PubMed Web of Science ®Google Scholar
• Sterne JAC, Savović J, Page MJ, et al. RoB 2: a revised tool for assessing risk of bias in randomised trials. BMJ. 2019;366:l4898. doi:10.1136/bmj.l4898
   PubMed Web of Science ®Google Scholar
• Descroix V, Coudert AE, Vigé A, et al. Efficacy of topical 1% lidocaine in the symptomatic treatment of pain associated with oral mucosal trauma or minor oral aphthous ulcer: a randomized, double-blind, placebo-controlled, parallel-group, single-dose study. J Orofac Pain. 2011;25(4):327–332.
   PubMedGoogle Scholar
• Giammarinaro E, Cosola S, Oldoini G, et al. Local formula with mucoadhesive property: a randomized clinical trial of a therapeutic agent for the treatment of oral aphthous ulcers. J Contemp Dent Pract. 2019;20(11):1249–1253. doi:10.5005/jp-journals-10024-2709
   Google Scholar
• Convissar RA, Massoumi-Sourey M. Recurrent aphthous ulcers: etiology and laser ablation. Gen Dent. 1992;40(6):512–515.
   Google Scholar
• De Souza TO, Martins MA, Bussadori SK, et al. Clinical evaluation of low-level laser treatment for recurring aphthous stomatitis. Photomed Laser Surg. 2010;28(Suppl 2):S85–S88. doi:10.1089/pho.2009.2661
   Web of Science ®Google Scholar
• Hristina Lalabonova HD, Daskalov H. Clinical assessment of the therapeutic effect of low-level laser therapy on chronic recurrent aphthous stomatitis. Biotechnol Biotechnol Equip. 2014;28(5):929–933. doi:10.1080/13102818.2014.966526
   Web of Science ®Google Scholar
• Jijin MJ, Rakaraddi M, Pai J, et al. Low-level laser therapy versus 5% amlexanox: a comparison of treatment effects in a cohort of patients with minor aphthous ulcers. Oral Surg Oral Med Oral Pathol Oral Radiol. 2016;121(3):269–273. doi:10.1016/j.oooo.2015.11.021
   Web of Science ®Google Scholar
• Nasry SA, El Shenawy HM, Mostafa D, Ammar NM. Different modalities for treatment of recurrent aphthous stomatitis. A randomized clinical trial. J Clin Exp Dent. 2016;8(5):e517–e522.
   Google Scholar
• Najeeb S, Khurshid Z, Zohaib S, Najeeb B, Qasim SB, Zafar MS. Management of recurrent aphthous ulcers using low-level lasers: a systematic review. Medicina. 2016;52(5):263–268. doi:10.1016/j.medici.2016.07.006
   Web of Science ®Google Scholar
• Arabaci T, Kara C, Ciçek Y. Relationship between periodontal parameters and Behçet’s disease and evaluation of different treatments for oral recurrent aphthous stomatitis. J Periodontal Res. 2009;44(6):718–725. doi:10.1111/j.1600-0765.2008.01183.x
   PubMed Web of Science ®Google Scholar
• Darshan DD, Kumar CN, Kumar AD, Manikantan NS, Balakrishnan D, Uthkal MP. Clinical study to know the efficacy of amlexanox 5% with other topical antiseptic, analgesic and anesthetic agents in treating minor RAS. J Int Oral Health. 2014;6(1):5–11.
   Google Scholar
• Rocca JP, Zhao M, Fornaini C, Tan L, Zhao Z, Merigo E. Effect of laser irradiation on aphthae pain management: a four different wavelengths comparison. J Photochem Photobiol B. 2018;189:1–4. doi:10.1016/j.jphotobiol.2018.09.016
   Web of Science ®Google Scholar
• Colvard M, Kuo P. Managing aphthous ulcers: laser treatment applied. J Am Dent Assoc. 1991;122(6):51–53. doi:10.1016/S0002-8177(91)26017-1
   Web of Science ®Google Scholar
• Sattayut S, Trivibulwanich J, Pipithirunkarn N, Danvirutai N. A clinical efficacy of using CO2 laser irradiating to transparent gel on aphthous stomatitis patients. Laser Ther. 2013;22(4):283–289. doi:10.5978/islsm.13-OR-24
   Google Scholar
• Volkov I, Rudoy I, Freud T, et al. Effectiveness of vitamin B12 in treating recurrent aphthous stomatitis: a randomized, double-blind, placebo-controlled trial. J Am Board Fam Med. 2009;22(1):9–16. doi:10.3122/jabfm.2009.01.080113
   Web of Science ®Google Scholar
• Yasui K, Kurata T, Yashiro M, Tsuge M, Ohtsuki S, Morishima T. The effect of ascorbate on minor recurrent aphthous stomatitis. Acta Paediatr. 2010;99(3):442–445. doi:10.1111/j.1651-2227.2009.01628.x
   Web of Science ®Google Scholar
• El Khouli AM, El-Gendy EA. Efficacy of omega-3 in treatment of recurrent aphthous stomatitis and improvement of quality of life: a randomized, double-blind, placebo-controlled study. Oral Surg Oral Med Oral Pathol Oral Radiol. 2014;117(2):191–196.
   Web of Science ®Google Scholar
• Nosratzehi T, Akar A. Efficacy of omega-3 in treatment of recurrent aphthous stomatitis: a randomised, double-blind, Placebo-controlled Study. Chin J Dent Res. 2016;19(3):159–164.
   Google Scholar
• Lalla RV, Choquette LE, Feinn RS, et al. Multivitamin therapy for recurrent aphthous stomatitis: a randomized, double-masked, placebo-controlled trial. J Am Dent Assoc. 2012;143(4):370–376. doi:10.14219/jada.archive.2012.0179
   Web of Science ®Google Scholar
• Spivakovsky S, Keenan AV. No effect seen for multivitamin therapy on recurrent aphthous stomatitis patients. Evid Based Dent. 2013;14(1):26.
   Google Scholar
• Chavan M, Jain H, Diwan N, Khedkar S, Shete A, Durkar S. Recurrent aphthous stomatitis: a review. J Oral Pathol Med. 2012;41(8):577–583. doi:10.1111/j.1600-0714.2012.01134.x
   PubMed Web of Science ®Google Scholar
• Preeti L, Magesh K, Rajkumar K, Karthik R. Recurrent aphthous stomatitis. J Oral Maxillofac Pathol. 2011;15(3):252–256. doi:10.4103/0973-029X.86669
   Google Scholar
• Liang MW, Neoh CY. Oral aphthosis: management gaps and recent advances. Ann Acad Med Singapore. 2012;41(10):463–470.
   Web of Science ®Google Scholar
• Han M, Fang H, Li QL, Cao Y, Xia R, Zhang ZH. Effectiveness of laser therapy in the management of recurrent aphthous stomatitis: a systematic review. Scientifica (Cairo). 2016;2016:9062430.
   PubMedGoogle Scholar