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ORIGINAL RESEARCH

Risk Factors of Microvascular Complications Among Type 2 Diabetic Patients Using Cox Proportional Hazards Models: A Cohort Study in Tabuk Saudi Arabia

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Pages 1619-1632 | Received 24 Mar 2022, Accepted 30 Jun 2022, Published online: 27 Jul 2022

References

  • Forouhi NG, Wareham NJ. Epidemiology of diabetes. Medicine. 2019;47(1):22–27. doi:10.1016/j.mpmed.2018.10.004
  • Harding JL, Pavkov ME, Magliano DJ, Shaw JE, Gregg EW. Global trends in diabetes complications: a review of current evidence. Diabetologia. 2019;62(1):3–16. doi:10.1007/s00125-018-4711-2
  • Misra A, Gopalan H, Jayawardena R, et al. Diabetes in developing countries. J Diabetes. 2019;11(7):522–539. doi:10.1111/1753-0407.12913
  • Robert AA, Al Dawish MA. The worrying trend of diabetes mellitus in Saudi Arabia: an urgent call to action. Curr Diabetes Rev. 2020;16(3):204–210. doi:10.2174/1573399815666190531093735
  • Abuyassin B, Laher I. Diabetes epidemic sweeping the Arab world. World J Diabetes. 2016;7(8):165. doi:10.4239/wjd.v7.i8.165
  • Buse JB, Davies MJ, Frier BM, Philis-Tsimikas A. 100 years on: the impact of the discovery of insulin on clinical outcomes. BMJ Open Diabetes Res Care. 2021;9(1):e002373. doi:10.1136/bmjdrc-2021-002373
  • Gregg EW, Sattar N, Ali MK. The changing face of diabetes complications. Lancet Diabetes Endocrinol. 2016;4(6):537–547. doi:10.1016/S2213-8587(16)30010-9
  • Liu J, Liu Z. Muscle insulin resistance and the inflamed microvasculature: fire from within. Int J Mol Sci. 2019;20(3):562. doi:10.3390/ijms20030562
  • Mauricio D, Alonso N, Gratacòs M. Chronic diabetes complications: the need to move beyond classical concepts. Trends Endocrinol Metab. 2020;31(4):287–295. doi:10.1016/j.tem.2020.01.007
  • Hussein M, Menasri S. Prevalence of microvascular complications in type 2 diabetics attending a primary healthcare centre in Sudan. Dubai Diabetes Endocrinol J. 2019;25(3–4):127–133. doi:10.1159/000500914
  • Faselis C, Katsimardou A, Imprialos K, Deligkaris P, Kallistratos M, Dimitriadis K. Microvascular complications of type 2 diabetes mellitus. Curr Vasc Pharmacol. 2020;18(2):117–124. doi:10.2174/1570161117666190502103733
  • Zheng Y, Ley SH, Hu FB. Global aetiology and epidemiology of type 2 diabetes mellitus and its complications. Nat Rev Endocrinol. 2018;14(2):88–98. doi:10.1038/nrendo.2017.151
  • Alramadan MJ, Magliano DJ, Alhamrani HA, et al. Lifestyle factors and macro-and micro-vascular complications among people with type 2 diabetes in Saudi Arabia. Diabetes Metab Syndrome Clin Res Rev. 2019;13(1):484–491. doi:10.1016/j.dsx.2018.11.007
  • Aschner P, Galstyan G, Yavuz DG, et al. Glycemic control and prevention of diabetic complications in low-and middle-income countries: an expert opinion. Diabetes Ther. 2021;12(5):1491–1501. doi:10.1007/s13300-021-00997-0
  • Alwin Robert A, Al Dawish MA. Microvascular complications among patients with diabetes: an emerging health problem in Saudi Arabia. Diabetes Vasc Dis Res. 2019;16(3):227–235. doi:10.1177/1479164118820714
  • Cheema S, Maisonneuve P, Zirie M, et al. Risk factors for microvascular complications of diabetes in a high-risk Middle East population. J Diabetes Res. 2018;2018. doi:10.1155/2018/8964027
  • Sendi RA, Mahrus AM, Saeed RM, Mohammed MA, Al-Dubai SAR. Diabetic peripheral neuropathy among Saudi diabetic patients: a multicenter cross-sectional study at primary health care setting. J Family Med Primary Care. 2020;9(1):197. doi:10.4103/jfmpc.jfmpc_927_19
  • Al-Ayed MY, Ababneh M, Robert AA, Salman A, Al Saeed A, Al Dawish MA. Evaluation of risk factors associated with diabetic foot ulcers in Saudi Arabia. Curr Diabetes Rev. 2019;15(3):224–232. doi:10.2174/1573399814666180816165848
  • Eng E, Quaggin S. Putting it all together: practical approach to the patient with diabetic kidney disease. In: Diabetes and Kidney Disease. Springer; 2022:637–659.
  • Bui HDT, Jing X, Lu R, et al. Prevalence of and factors related to microvascular complications in patients with type 2 diabetes mellitus in Tianjin, China: a cross-sectional study. Ann Transl Med. 2019;7:14. doi:10.21037/atm.2019.06.08
  • Seid MA, Akalu Y, Gela YY, et al. Microvascular complications and its predictors among type 2 diabetes mellitus patients at Dessie town hospitals, Ethiopia. Diabetol Metab Syndr. 2021;13(1):1–8.
  • Khalil SA, Megallaa MH, Rohoma KH, et al. Prevalence of chronic diabetic complications in newly diagnosed versus known type 2 diabetic subjects in a sample of Alexandria population, Egypt. Curr Diabetes Rev. 2019;15(1):74–83. doi:10.2174/1573399814666180125100917
  • Teo ZL, Tham Y-C, Yu M, et al. Global prevalence of diabetic retinopathy and projection of burden through 2045: systematic review and meta-analysis. Ophthalmology. 2021;128(11):1580–1591. doi:10.1016/j.ophtha.2021.04.027
  • Ting DSW, Cheung GCM, Wong TY. Diabetic retinopathy: global prevalence, major risk factors, screening practices and public health challenges: a review. Clin Experiment Ophthalmol. 2016;44(4):260–277. doi:10.1111/ceo.12696
  • Lin YK, Gao B, Liu L, et al. The prevalence of diabetic microvascular complications in China and the USA. Curr Diab Rep. 2021;21(6):1–11. doi:10.1007/s11892-021-01387-3
  • Afroz A, Zhang W, Loh AJW, Lee DXJ, Billah B. Macro-and micro-vascular complications and their determinants among people with type 2 diabetes in Bangladesh. Diabetes Metab Syndrome Clin Res Rev. 2019;13(5):2939–2946. doi:10.1016/j.dsx.2019.07.046
  • Nørgaard CH, Mosslemi M, Lee CJ-Y, Torp-Pedersen C, Wong ND. The importance and role of multiple risk factor control in type 2 diabetes. Curr Cardiol Rep. 2019;21(5):1–10. doi:10.1007/s11886-019-1123-y
  • Nanayakkara N, Ranasinha S, Gadowski A, et al. Age, age at diagnosis and diabetes duration are all associated with vascular complications in type 2 diabetes. J Diabetes Complications. 2018;32(3):279–290. doi:10.1016/j.jdiacomp.2017.11.009
  • Khanam PA, Hoque S, Begum T, Habib SH, Latif ZA. Microvascular complications and their associated risk factors in type 2 diabetes mellitus. Diabetes Metab Syndrome Clin Res Rev. 2017;11:S577–S81. doi:10.1016/j.dsx.2017.04.007
  • Szwarcbard N, Villani M, Earnest A, et al. The association of smoking status with glycemic control, metabolic profile and diabetic complications–results of the Australian National diabetes audit (ANDA). J Diabetes Complications. 2020;34(9):107626. doi:10.1016/j.jdiacomp.2020.107626
  • Gedebjerg A, Almdal TP, Berencsi K, et al. Prevalence of micro-and macrovascular diabetes complications at time of type 2 diabetes diagnosis and associated clinical characteristics: a cross-sectional baseline study of 6958 patients in the Danish DD2 cohort. J Diabetes Complications. 2018;32(1):34–40. doi:10.1016/j.jdiacomp.2017.09.010
  • Kosiborod M, Gomes MB, Nicolucci A, et al. Vascular complications in patients with type 2 diabetes: prevalence and associated factors in 38 countries (the DISCOVER study program). Cardiovasc Diabetol. 2018;17(1):1–13. doi:10.1186/s12933-018-0787-8
  • Zhao H, Shu L, Huang W, Wang W, Song G. Difference analysis of related factors in macrovascular and microvascular complications in Chinese patients with Type 2 diabetes mellitus: a case-control study protocol. Diabetes, Metab Syndrome Obesity Targets Ther. 2019;12:2193. doi:10.2147/DMSO.S213848
  • Narindrarangkura P, Bosl W, Rangsin R, Hatthachote P. Prevalence of dyslipidemia associated with complications in diabetic patients: a nationwide study in Thailand. Lipids Health Dis. 2019;18(1):1–8. doi:10.1186/s12944-019-1034-3
  • Tilahun M, Gobena T, Dereje D, Welde M, Yideg G. Prevalence of diabetic retinopathy and its associated factors among diabetic patients at Debre Markos referral hospital, Northwest Ethiopia, 2019: hospital-Based Cross-Sectional Study. Diabetes, Metab Syndrome Obesity Targets Ther. 2020;13:2179. doi:10.2147/DMSO.S260694
  • Leley SP, Ciulla TA, Bhatwadekar AD. Diabetic retinopathy in the aging population: a perspective of pathogenesis and treatment. Clin Interv Aging. 2021;16:1367. doi:10.2147/CIA.S297494
  • Sultan S, Fawwad A, Siyal NA, Butt A, Khokar AR, Basit A. Frequency and risk factors of diabetic retinopathy in patients with type 2 diabetes presenting at a tertiary care hospital. Int J Diabetes Dev Ctries. 2020;40(1):87–92. doi:10.1007/s13410-019-00756-9
  • Giri B, Dey S, Das T, Sarkar M, Banerjee J, Dash SK. Chronic hyperglycemia mediated physiological alteration and metabolic distortion leads to organ dysfunction, infection, cancer progression and other pathophysiological consequences: an update on glucose toxicity. Biomed Pharmacother. 2018;107:306–328.
  • Cherchi S, Gigante A, Spanu MA, et al. Sex-gender differences in diabetic retinopathy. Diabetology. 2020;1(1):1–10. doi:10.3390/diabetology1010001
  • Kozioł M, Nowak MS, Udziela M, Piątkiewicz P, Grabska-Liberek I, Szaflik JP. First nation-wide study of diabetic retinopathy in Poland in the years 2013–2017. Acta Diabetol. 2020;57(10):1255–1264. doi:10.1007/s00592-020-01540-6
  • Wu Y-B, Wang C-G, Xu L-X, Chen C, Zhou X-B, Su G-F. Analysis of risk factors for progressive fibrovascular proliferation in proliferative diabetic retinopathy. Int Ophthalmol. 2020;40(10):2495–2502. doi:10.1007/s10792-020-01428-y
  • West SK. Smoking and the risk of eye diseases. In: Nutritional and Environmental Influences on the Eye. CRC Press; 2021:151–164.
  • Cai X, Chen Y, Yang W, Gao X, Han X, Ji L. The association of smoking and risk of diabetic retinopathy in patients with type 1 and type 2 diabetes: a meta-analysis. Endocrine. 2018;62(2):299–306. doi:10.1007/s12020-018-1697-y
  • Chan JCY, Chee ML, Tan NYQ, Cheng C-Y, Wong TY, Sabanayagam C. Differential effect of body mass index on the incidence of diabetes and diabetic retinopathy in two Asian populations. Nutr Diabetes. 2018;8(1):1–11. doi:10.1016/j.cegh.2019.08.019
  • Yuanyuan C, Shuli Q, Yanjun L, Yuqi Z, Wenjie X, Li C. Meta-analysis of the epidemiology of microvascular complications in people with Type 2 diabetes in mainland China. Global J Obesity, Diabetes Metab Syndrome. 2020;7(2):018–23. doi:10.17352/2455-8583.000042
  • Fawwad A, Mustafa N, Zafar AB, Khalid M. Incidence of microvascular complications of type 2 diabetes: a 12 year longitudinal study from Karachi-Pakistan. Pak J Med Sci. 2018;34(5):1058. doi:10.12669/pjms.345.15224
  • Yildiz M, Esenboga K, Oktay AA. Hypertension and diabetes mellitus: highlights of a complex relationship. Curr Opin Cardiol. 2020;35(4):397–404. doi:10.1097/HCO.0000000000000748
  • Yamazaki D, Hitomi H, Nishiyama A. Hypertension with diabetes mellitus complications. Hypertens Res. 2018;41(3):147–156. doi:10.1038/s41440-017-0008-y
  • Alramadan MJ, Magliano DJ, Almigbal TH, et al. Glycaemic control for people with type 2 diabetes in Saudi Arabia–an urgent need for a review of management plan. BMC Endocr Disord. 2018;18(1):1–12. doi:10.1186/s12902-018-0292-9
  • D’Souza MS, Labrague LJ, Karkada SN, Kamble P. Relationship between socio-demographic, clinical factors, and quality of life in adults living with diabetic nephropathy. Clin Epidemiol Global Health. 2020;8(2):343–349.
  • Savelieff MG, Callaghan BC, Feldman EL. The emerging role of dyslipidemia in diabetic microvascular complications. Curr Opin Endocrinol Diabetes Obes. 2020;27(2):115–123. doi:10.1097/MED.0000000000000533
  • Singh SS, Rashid M, Lieverse AG, et al. Lipoprotein (a) plasma levels are not associated with incident microvascular complications in type 2 diabetes mellitus. Diabetologia. 2020;63(6):1248–1257. doi:10.1007/s00125-020-05120-9