144
Views
2
CrossRef citations to date
0
Altmetric
ORIGINAL RESEARCH

Age and Sex Differences Among Mildly Symptomatic and Asymptomatic Patients with Omicron Infection in 2022 in Shanghai, China

ORCID Icon, , , , ORCID Icon, , , , & ORCID Icon show all
Pages 1909-1919 | Received 22 May 2022, Accepted 24 Aug 2022, Published online: 31 Aug 2022

References

  • Team CC-R. SARS-CoV-2 B.1.1.529 (Omicron) Variant - United States, December 1–8, 2021. MMWR Morb Mortal Wkly Rep. 2021;70(50):1731–1734. doi:10.15585/mmwr.mm7050e1
  • Pujadas E, Chaudhry F, McBride R, et al. SARS-CoV-2 viral load predicts COVID-19 mortality. Lancet Respir Med. 2020;8(9):e70. doi:10.1016/S2213-2600(20)30354-4
  • Magleby R, Westblade LF, Trzebucki A, et al. Impact of severe acute respiratory syndrome coronavirus 2 viral load on risk of intubation and mortality among hospitalized patients with coronavirus disease 2019. Clin Infect Dis. 2021;73(11):e4197–e4205. doi:10.1093/cid/ciaa851
  • Wang H, Liu Q, Hu J, et al. Nasopharyngeal swabs are more sensitive than oropharyngeal swabs for COVID-19 diagnosis and monitoring the SARS-CoV-2 load. Front Med. 2020;7:334. doi:10.3389/fmed.2020.00334
  • Heald-Sargent T, Muller WJ, Zheng X, Rippe J, Patel AB, Kociolek LK. Age-related differences in nasopharyngeal severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) levels in patients with mild to moderate coronavirus disease 2019 (COVID-19). JAMA Pediatr. 2020;174(9):902–903. doi:10.1001/jamapediatrics.2020.3651
  • Miranda RL, Guterres A, De azeredo lima CH, Filho PN, Gadelha MR. Misinterpretation of viral load in COVID-19 clinical outcomes. Virus Res. 2021;296:198340. doi:10.1016/j.virusres.2021.198340
  • Fall A, Eldesouki RE, Sachithanandham J, et al. The displacement of the SARS-CoV-2 variant Delta with Omicron: an investigation of hospital admissions and upper respiratory viral loads. EBioMedicine. 2022;79:104008. doi:10.1016/j.ebiom.2022.104008
  • Malik JA, Mulla AH, Farooqi T, Pottoo FH, Anwar S, Rengasamy KRR. Targets and strategies for vaccine development against SARS-CoV-2. Biomed Pharmacother. 2021;137:111254. doi:10.1016/j.biopha.2021.111254
  • Wan Z, Lu R, Zhao Y, Zhang C. Diagnostic strategy of SARS-CoV-2 for containment under China’s zero-COVID-19 policy. J Infect. 2022;85:e7–e9. doi:10.1016/j.jinf.2022.04.044
  • Farooqi T, Malik JA, Mulla AH, et al. An overview of SARS-COV-2 epidemiology, mutant variants, vaccines, and management strategies. J Infect Public Health. 2021;14(10):1299–1312. doi:10.1016/j.jiph.2021.08.014
  • Malik JA, Ahmed S, Mir A, et al. The SARS-CoV-2 mutations versus vaccine effectiveness: new opportunities to new challenges. J Infect Public Health. 2022;15(2):228–240. doi:10.1016/j.jiph.2021.12.014
  • Jacot D, Greub G, Jaton K, Opota O. Viral load of SARS-CoV-2 across patients and compared to other respiratory viruses. Microbes Infect. 2020;22(10):617–621. doi:10.1016/j.micinf.2020.08.004
  • Chen J, Wang R, Gilby NB, Wei GW. Omicron variant (B.1.1.529): infectivity, vaccine breakthrough, and antibody resistance. J Chem Inf Model. 2022;62(2):412–422. doi:10.1021/acs.jcim.1c01451
  • Khandia R, Singhal S, Alqahtani T, et al. Emergence of SARS-CoV-2 Omicron (B.1.1.529) variant, salient features, high global health concerns and strategies to counter it amid ongoing COVID-19 pandemic. Environ Res. 2022;209:112816. doi:10.1016/j.envres.2022.112816
  • Malik JA, Aroosa M, Ahmed S, et al. SARS-CoV-2 vaccines: clinical endpoints and psychological perspectives: a literature review. J Infect Public Health. 2022;15(5):515–525. doi:10.1016/j.jiph.2022.03.017
  • Rao SN, Manissero D, Steele VR, Pareja J. A systematic review of the clinical utility of cycle threshold values in the context of COVID-19. Infect Dis Ther. 2020;9(3):573–586. doi:10.1007/s40121-020-00324-3
  • Asai N, Sakanashi D, Ohashi W, et al. Could threshold cycle value correctly reflect the severity of novel coronavirus disease 2019 (COVID-19)? J Infect Chemother. 2021;27(1):117–119. doi:10.1016/j.jiac.2020.09.010
  • La Scola B, Le Bideau M, Andreani J, et al. Viral RNA load as determined by cell culture as a management tool for discharge of SARS-CoV-2 patients from infectious disease wards. Eur J Clin Microbiol Infect Dis. 2020;39(6):1059–1061. doi:10.1007/s10096-020-03913-9
  • Domeracki S, Clapp RN, Taylor K, Lu CM, Lampiris H, Blanc PD. Cycle threshold to test positivity in COVID-19 for return to work clearance in health care workers. J Occup Environ Med. 2020;62(11):889–891. doi:10.1097/JOM.0000000000001996
  • Dergaa I, Abubaker M, Souissi A, et al. Age and clinical signs as predictors of COVID-19 symptoms and cycle threshold value. Libyan J Med. 2022;17(1):2010337. doi:10.1080/19932820.2021.2010337
  • Patel MR, Carroll D, Ussery E, et al. Performance of oropharyngeal swab testing compared with nasopharyngeal swab testing for diagnosis of coronavirus disease 2019-United States, January 2020-February 2020. Clin Infect Dis. 2021;72(3):403–410. doi:10.1093/cid/ciaa759
  • Andriamandimby SF, Brook CE, Razanajatovo N, et al. Cross-sectional cycle threshold values reflect epidemic dynamics of COVID-19 in Madagascar. Epidemics. 2022;38:100533. doi:10.1016/j.epidem.2021.100533
  • Gupta A, Bhanushali S, Sanap A, et al. Oral dysbiosis and its linkage with SARS-CoV-2 infection. Microbiol Res. 2022;261:127055. doi:10.1016/j.micres.2022.127055
  • Ur Rehman M, Sajjad Naqvi S, Ullah R, et al. Elucidation of correlation between SARS-CoV-2 RdRp and N gene cycle threshold (Ct) by RT-PCR with age and gender. Clin Chim Acta. 2022;533:42–47. doi:10.1016/j.cca.2022.06.008
  • To KK, Tsang OT, Leung WS, et al. Temporal profiles of viral load in posterior oropharyngeal saliva samples and serum antibody responses during infection by SARS-CoV-2: an observational cohort study. Lancet Infect Dis. 2020;20(5):565–574. doi:10.1016/S1473-3099(20)30196-1
  • Albanghali M, Alghamdi S, Alzahrani M, et al. Clinical characteristics and treatment outcomes of mild to moderate COVID-19 patients at tertiary care hospital, al baha, Saudi Arabia: a single centre study. J Infect Public Health. 2022;15(3):331–337. doi:10.1016/j.jiph.2022.02.001
  • Chen WJ, Yang JY, Lin JH, et al. Nasopharyngeal shedding of severe acute respiratory syndrome-associated coronavirus is associated with genetic polymorphisms. Clin Infect Dis. 2006;42(11):1561–1569. doi:10.1086/503843
  • Ahmad Malik J, Ahmed S, Shinde M, et al. The impact of COVID-19 on comorbidities: a review of recent updates for combating it. Saudi J Biol Sci. 2022;29(5):3586–3599. doi:10.1016/j.sjbs.2022.02.006
  • Zhang X, Zhang W, Chen S. Shanghai’s life-saving efforts against the current omicron wave of the COVID-19 pandemic. Lancet. 2022;399:2011–2012. doi:10.1016/S0140-6736(22)00838-8