Effects of a Mobile-Health Exercise Intervention on Body Composition, Vascular Function, and Autonomic Nervous System Function in Obese Women: A Randomized Controlled Trial

References

• WHO. WHO discussion paper: draft recommendations for the prevention and management of obesity over the life course, including potential targets; 2021.
   Google Scholar
• Manrique-Acevedo C, Chinnakotla B, Padilla J, Martinez-Lemus LA, Gozal D. Obesity and cardiovascular disease in women. Int J Obes. 2020;44(6):1210–1226.
   PubMed Web of Science ®Google Scholar
• NCD Risk Factor Collaboration (NCD-RisC). Trends in adult body-mass index in 200 countries from 1975 to 2014: a pooled analysis of 1698 population-based measurement studies with 19·2 million participants. Lancet. 2016;387(10026):1377–1396. doi:10.1016/S0140-6736(16)30054-X
   PubMed Web of Science ®Google Scholar
• Guarino D, Nannipieri M, Iervasi G, Taddei S, Bruno RM. The role of the autonomic nervous system in the pathophysiology of obesity. Front Physiol. 2017;8:665. doi:10.3389/fphys.2017.00665
   PubMed Web of Science ®Google Scholar
• Talmor A, Dunphy B. Female obesity and infertility. Best Pract Res Clin Obstet Gynaecol. 2015;29(4):498–506. doi:10.1016/j.bpobgyn.2014.10.014
   PubMed Web of Science ®Google Scholar
• Mitchell GF. Arterial stiffness and wave reflection: biomarkers of cardiovascular risk. Artery Res. 2009;3(2):56–64. doi:10.1016/j.artres.2009.02.002
   PubMedGoogle Scholar
• Sprung VS, Bowden Davies KA, Norman JA, et al. Metabolic syndrome is associated with reduced flow mediated dilation independent of obesity status. Eur J Endocrinol. 2020;183(2):211–220. doi:10.1530/EJE-20-0098
   PubMed Web of Science ®Google Scholar
• Mozos I, Malainer C, Horbańczuk J, et al. Inflammatory markers for arterial stiffness in cardiovascular diseases. Front Immunol. 2017;8:1058. doi:10.3389/fimmu.2017.01058
   PubMed Web of Science ®Google Scholar
• Flammer AJ, Anderson T, Celermajer DS, et al. The assessment of endothelial function: from research into clinical practice. Circulation. 2012;126(6):753–767. doi:10.1161/CIRCULATIONAHA.112.093245
   PubMed Web of Science ®Google Scholar
• Appelman Y, van Rijn BB, Ten Haaf ME, Boersma E, Peters SAE, van Rijn BB. Sex differences in cardiovascular risk factors and disease prevention. Atherosclerosis. 2015;241(1):211–218. doi:10.1016/j.atherosclerosis.2015.01.027
   PubMed Web of Science ®Google Scholar
• Abiri B, Hosseinpanah F, Banihashem S, Madinehzad SA, Valizadeh M. Mental health and quality of life in different obesity phenotypes: a systematic review. Health Qual Life Outcomes. 2022;20(1):63. doi:10.1186/s12955-022-01974-2
   PubMed Web of Science ®Google Scholar
• Guan L, Collet JP, Mazowita G, Claydon VE. Autonomic nervous system and stress to predict secondary ischemic events after transient ischemic attack or minor stroke: possible implications of heart rate variability. Front Neurol. 2018;9:90. doi:10.3389/fneur.2018.00090
   PubMed Web of Science ®Google Scholar
• Oliveira C, Silveira EA, Rosa L, et al. Risk factors associated with cardiac autonomic modulation in obese individuals. J Obes. 2020;2020:7185249. doi:10.1155/2020/7185249
   PubMed Web of Science ®Google Scholar
• Bellicha A, van Baak MA, Battista F, et al. Effect of exercise training on weight loss, body composition changes, and weight maintenance in adults with overweight or obesity: an overview of 12 systematic reviews and 149 studies. Obes Rev. 2021;22(Suppl 4):e13256. doi:10.1111/obr.13256
   PubMedGoogle Scholar
• Petridou A, Siopi A, Mougios V. Exercise in the management of obesity. Metabolism. 2019;92:163–169. doi:10.1016/j.metabol.2018.10.009
   PubMed Web of Science ®Google Scholar
• Fiuza-Luces C, Santos-Lozano A, Joyner M, et al. Exercise benefits in cardiovascular disease: beyond attenuation of traditional risk factors. Nat Rev Cardiol. 2018;15(12):731–743. doi:10.1038/s41569-018-0065-1
   PubMed Web of Science ®Google Scholar
• van der Ploeg HP, Bull FC. Invest in physical activity to protect and promote health: the 2020 WHO guidelines on physical activity and sedentary behaviour. Int J Behav Nutr Phys Act. 2020;17(1):145. doi:10.1186/s12966-020-01051-1
   PubMed Web of Science ®Google Scholar
• Costa J, Moreira A, Moreira P, Delgado L, Silva D. Effects of weight changes in the autonomic nervous system: a systematic review and meta-analysis. Clin Nutr. 2019;38(1):110–126. doi:10.1016/j.clnu.2018.01.006
   PubMed Web of Science ®Google Scholar
• Fu Q, Levine BD. Exercise and the autonomic nervous system. Handb Clin Neurol. 2013;117:147–160.
   PubMedGoogle Scholar
• Smahel D, Elavsky S, Machackova H. Functions of mHealth applications: a user’s perspective. Health Informatics J. 2019;25(3):1065–1075. doi:10.1177/1460458217740725
   PubMed Web of Science ®Google Scholar
• Kim S-W, Choi J-H, Sun Y, et al. Effect of a 12-week non-contact exercise intervention on body composition and health-related physical fitness in adults: a pilot test. Phys Act Nutr. 2022;26(3):32–36. doi:10.20463/pan.2022.0016
   PubMedGoogle Scholar
• Park E. User acceptance of smart wearable devices: an expectation-confirmation model approach. Telemat Inform. 2020;47:101318. doi:10.1016/j.tele.2019.101318
   Web of Science ®Google Scholar
• Gal R, May AM, van Overmeeren EJ, Simons M, Monninkhof EM. The effect of physical activity interventions comprising wearables and smartphone applications on physical activity: a systematic review and meta-analysis. Sports Med Open. 2018;4(1):42. doi:10.1186/s40798-018-0157-9
   PubMedGoogle Scholar
• Cadmus-Bertram LA, Marcus BH, Patterson RE, Parker BA, Morey BL. Randomized trial of a fitbit-based physical activity intervention for women. Am J Prev Med. 2015;49(3):414–418. doi:10.1016/j.amepre.2015.01.020
   PubMed Web of Science ®Google Scholar
• Hartman SJ, Nelson SH, Cadmus-Bertram LA, Patterson RE, Parker BA, Pierce JP. Technology- and phone-based weight loss intervention: pilot RCT in women at elevated breast cancer risk. Am J Prev Med. 2016;51(5):714–721. doi:10.1016/j.amepre.2016.06.024
   PubMed Web of Science ®Google Scholar
• Chow CK, Redfern J, Hillis GS, et al. Effect of lifestyle-focused text messaging on risk factor modification in patients with coronary heart disease: a randomized clinical trial. JAMA. 2015;314(12):1255–1263. doi:10.1001/jama.2015.10945
   PubMed Web of Science ®Google Scholar
• Lopez C, McGarragle K, Pritlove C, et al. Variability and limitations in home-based exercise program descriptions in oncology: a scoping review. Support Care Cancer. 2020;28(9):4005–4017. doi:10.1007/s00520-020-05453-6
   PubMed Web of Science ®Google Scholar
• Gell NM, Grover KW, Savard L, Dittus K. Outcomes of a text message, fitbit, and coaching intervention on physical activity maintenance among cancer survivors: a randomized control pilot trial. J Cancer Surviv. 2020;14(1):80–88. doi:10.1007/s11764-019-00831-4
   PubMed Web of Science ®Google Scholar
• Ryu S, Chang Y, Jung HS, et al. Relationship of sitting time and physical activity with non-alcoholic fatty liver disease. J Hepatol. 2015;63(5):1229–1237. doi:10.1016/j.jhep.2015.07.010
   PubMed Web of Science ®Google Scholar
• Garber CE, Blissmer B, Deschenes MR, et al. American college of sports medicine position stand. Quantity and quality of exercise for developing and maintaining cardiorespiratory, musculoskeletal, and neuromotor fitness in apparently healthy adults: guidance for prescribing exercise. Med Sci Sports Exerc. 2011;43(7):1334–1359. doi:10.1249/MSS.0b013e318213fefb
   PubMed Web of Science ®Google Scholar
• Hammami A, Harrabi B, Mohr M, Krustrup P. Physical activity and coronavirus disease 2019 (COVID-19): specific recommendations for home-based physical training. Manag Sport Leis. 2022;27(1–2):26–31. doi:10.1080/23750472.2020.1757494
   Web of Science ®Google Scholar
• Bai Y, Hibbing P, Mantis C, Welk GJ. Comparative evaluation of heart rate-based monitors: apple watch vs fitbit charge HR. J Sports Sci. 2018;36(15):1734–1741. doi:10.1080/02640414.2017.1412235
   PubMed Web of Science ®Google Scholar
• Diaz KM, Krupka DJ, Chang MJ, et al. Fitbit®: an accurate and reliable device for wireless physical activity tracking. Int J Cardiol. 2015;185:138–140. doi:10.1016/j.ijcard.2015.03.038
   PubMed Web of Science ®Google Scholar
• Huh U, Tak YJ, Song S, et al. Feedback on physical activity through a wearable device connected to a mobile phone app in patients with metabolic syndrome: pilot study. JMIR Mhealth Uhealth. 2019;7(6):e13381. doi:10.2196/13381
   PubMed Web of Science ®Google Scholar
• Piotrowicz E, Buchner T, Piotrowski W, Piotrowicz R. Influence of home-based telemonitored Nordic walking training on autonomic nervous system balance in heart failure patients. Arch Med Sci. 2015;11(6):1205–1212. doi:10.5114/aoms.2015.56346
   PubMed Web of Science ®Google Scholar
• Rubinstein A, Miranda JJ, Beratarrechea A, et al. Effectiveness of an mHealth intervention to improve the cardiometabolic profile of people with prehypertension in low-resource urban settings in Latin America: a randomised controlled trial. Lancet Diabetes Endocrinol. 2016;4(1):52–63. doi:10.1016/S2213-8587(15)00381-2
   PubMed Web of Science ®Google Scholar
• Bull FC, Al-Ansari SS, Biddle S, et al. World Health Organization 2020 guidelines on physical activity and sedentary behaviour. Br J Sports Med. 2020;54(24):1451–1462. doi:10.1136/bjsports-2020-102955
   PubMed Web of Science ®Google Scholar
• Hill AM, Buckley JD, Murphy KJ, Howe PR. Combining fish-oil supplements with regular aerobic exercise improves body composition and cardiovascular disease risk factors. Am J Clin Nutr. 2007;85(5):1267–1274. doi:10.1093/ajcn/85.5.1267
   PubMed Web of Science ®Google Scholar
• Liu Y, Lee DC, Li Y, et al. Associations of resistance exercise with cardiovascular disease morbidity and mortality. Med Sci Sports Exerc. 2019;51(3):499–508. doi:10.1249/MSS.0000000000001822
   PubMed Web of Science ®Google Scholar
• Hernández-Reyes A, Cámara-Martos F, Molina-Luque R, Moreno-Rojas R. Effect of an mHealth intervention using a pedometer app with full in-person counseling on body composition of overweight adults: randomized controlled weight loss trial. JMIR Mhealth Uhealth. 2020;8(5):e16999. doi:10.2196/16999
   PubMed Web of Science ®Google Scholar
• Schneider PL, Bassett DR Jr, Thompson DL, Pronk NP, Bielak KM. Effects of a 10,000 steps per day goal in overweight adults. Am J Health Promot. 2006;21(2):85–89. doi:10.4278/0890-1171-21.2.85
   PubMed Web of Science ®Google Scholar
• Sheng Y, Zhu L. The crosstalk between autonomic nervous system and blood vessels. Int J Physiol Pathophysiol Pharmacol. 2018;10(1):17–28.
   PubMedGoogle Scholar
• Sun SS, Grave GD, Siervogel RM, Pickoff AA, Arslanian SS, Daniels SR. Systolic blood pressure in childhood predicts hypertension and metabolic syndrome later in life. Pediatrics. 2007;119(2):237–246. doi:10.1542/peds.2006-2543
   PubMed Web of Science ®Google Scholar
• Green DJ, Maiorana A, O’Driscoll G, Taylor R. Effect of exercise training on endothelium-derived nitric oxide function in humans. J Physiol. 2004;561(Pt 1):1–25. doi:10.1113/jphysiol.2004.068197
   PubMed Web of Science ®Google Scholar
• Mahalakshmi B, Maurya N, Lee S-D, Bharath Kumar V. Possible neuroprotective mechanisms of physical exercise in neurodegeneration. Int J Mol Sci. 2020;21(16):5895. doi:10.3390/ijms21165895
   PubMed Web of Science ®Google Scholar
• Yang SJ, Hong HC, Choi HY, et al. Effects of a three-month combined exercise programme on fibroblast growth factor 21 and fetuin-A levels and arterial stiffness in obese women. Clin Endocrinol. 2011;75(4):464–469. doi:10.1111/j.1365-2265.2011.04078.x
   PubMed Web of Science ®Google Scholar
• Pescatello LS, Guidry MA, Blanchard BE, et al. Exercise intensity alters postexercise hypotension. J Hypertens. 2004;22(10):1881–1888. doi:10.1097/00004872-200410000-00009
   PubMed Web of Science ®Google Scholar
• Pasqualini L, Bagaglia F, Ministrini S, et al. Effects of structured home-based exercise training on circulating endothelial progenitor cells and endothelial function in patients with intermittent claudication. Vasc Med. 2021;26(6):633–640. doi:10.1177/1358863X211020822
   PubMed Web of Science ®Google Scholar
• Watts K, Beye P, Siafarikas A, et al. Effects of exercise training on vascular function in obese children. J Pediatr. 2004;144(5):620–625. doi:10.1016/j.jpeds.2004.02.027
   PubMed Web of Science ®Google Scholar
• Park HY, Jung WS, Kim J, Hwang H, Lim K. Twelve weeks of aerobic exercise at the lactate threshold improves autonomic nervous system function, body composition, and aerobic performance in women with obesity. J Obes Metab Syndr. 2020;29(1):67–75. doi:10.7570/jomes19063
   PubMed Web of Science ®Google Scholar
• Matsumoto T, Miyawaki C, Ue H, Kanda T, Yoshitake Y, Moritani T. Comparison of thermogenic sympathetic response to food intake between obese and non-obese young women. Obes Res. 2001;9(2):78–85. doi:10.1038/oby.2001.10
   PubMedGoogle Scholar
• Poirier P, Hernandez TL, Weil KM, Shepard TJ, Eckel RH. Impact of diet-induced weight loss on the cardiac autonomic nervous system in severe obesity. Obes Res. 2003;11(9):1040–1047. doi:10.1038/oby.2003.143
   PubMedGoogle Scholar
• Picard M, Tauveron I, Magdasy S, et al. Effect of exercise training on heart rate variability in type 2 diabetes mellitus patients: a systematic review and meta-analysis. PLoS One. 2021;16(5):e0251863. doi:10.1371/journal.pone.0251863
   PubMed Web of Science ®Google Scholar
• Routledge FS, Campbell TS, McFetridge-Durdle JA, Bacon SL. Improvements in heart rate variability with exercise therapy. Can J Cardiol. 2010;26(6):303–312. doi:10.1016/S0828-282X(10)70395-0
   PubMed Web of Science ®Google Scholar