Search in:

Journal of Pain Research Volume 10, 2017 - Issue

Submit an article Journal homepage

Open access

274

Views

CrossRef citations to date

Altmetric

Review

Perineural versus intravenous dexamethasone as an adjuvant in regional anesthesia: a systematic review and meta-analysis

Wen-Ling Zhao1 Laboratory of Anesthesia and Critical Care Medicine, Translational Neuroscience Centre

Xiao-Feng Ou1 Laboratory of Anesthesia and Critical Care Medicine, Translational Neuroscience Centre

Jin Liu1 Laboratory of Anesthesia and Critical Care Medicine, Translational Neuroscience Centre;2 Department of Anesthesiology, West China Hospital, Sichuan University, Chengdu, China

Wen-Sheng Zhang1 Laboratory of Anesthesia and Critical Care Medicine, Translational Neuroscience Centre;2 Department of Anesthesiology, West China Hospital, Sichuan University, Chengdu, ChinaCorrespondence[email protected]

Pages 1529-1543 | Published online: 04 Jul 2017

Cite this article
CrossMark

Full Article
Figures & data
References
Citations
Metrics
Licensing
Reprints & Permissions
View PDF PDF

References

AbdelmonemARizkSNComparative study between intravenous and local dexamethasone as adjuvant to bupivacaine in perianal blockEgypt J Anaesth2011273163168
Google Scholar
DesmetMBraemsHReynvoetMI.V. and perineural dexamethasone are equivalent in increasing the analgesic duration of a single-shot interscalene block with ropivacaine for shoulder surgery: a prospective, randomized, placebo-controlled studyBr J Anaesth2013111344545223587875
PubMed Web of Science ®Google Scholar
KawanishiRYamamotoKTobettoYPerineural but not systemic low-dose dexamethasone prolongs the duration of interscalene block with ropivacaine: a prospective randomized trialLocal Reg Anesth201475924817819
PubMedGoogle Scholar
RahangdaleRKendallMCMcCarthyRJThe effects of perineural versus intravenous dexamethasone on sciatic nerve blockade outcomes: a randomized, double-blind, placebo-controlled studyAnesth Analg201411851113111924686045
PubMed Web of Science ®Google Scholar
AbdallahFWJohnsonJChanVIntravenous dexamethasone and perineural dexamethasone similarly prolong the duration of analgesia after supraclavicular brachial plexus block: a randomized, triple-arm, double-blind, placebo-controlled trialReg Anesth Pain Med201540212513225629321
PubMed Web of Science ®Google Scholar
RosenfeldDMIvancicMGHattrupSJPerineural versus intra-venous dexamethasone as adjuncts to local anaesthetic brachial plexus block for shoulder surgeryAnaesthesia201671438038826899862
PubMed Web of Science ®Google Scholar
ChunEHKimYJWooJHWhich is your choice for prolonging the analgesic duration of single-shot interscalene brachial blocks for arthroscopic shoulder surgery? Intravenous dexamethasone 5 mg vs. perineural dexamethasone 5 mg randomized, controlled, clinical trialMedicine (Baltimore)20169523e382827281084
PubMed Web of Science ®Google Scholar
AlisteJLeurcharusmeePEngsusophonPA randomized comparison between intravenous and perineural dexamethasone for ultrasound-guided axillary blockCan J Anaesth2017641293627663451
PubMed Web of Science ®Google Scholar
DawsonRLMcLeodDHKoerberJPPlummerJLDracopoulosGCA randomised controlled trial of perineural vs intravenous dexamethasone for foot surgeryAnaesthesia201671328529026682721
PubMed Web of Science ®Google Scholar
LeurcharusmeePAlisteJVan ZundertTCA multicenter randomized comparison between intravenous and perineural dexamethasone for ultrasound-guided infraclavicular blockReg Anesth Pain Med201641332833327015546
PubMed Web of Science ®Google Scholar
ChunEHKimYJWooJHWhich is your choice for prolonging the analgesic duration of single-shot interscalene brachial blocks for arthroscopic shoulder surgery? Intravenous dexamethasone 5 mg vs. perineural dexamethasone 5 mg randomized, controlled, clinical trialMedicine (Baltimore)20169523e382827281084
PubMed Web of Science ®Google Scholar

References

MillerRDMiller’s Anesthesia7th edPhiladelphiaChurchill Livingstone2009
Google Scholar
CandidoKDKnezevicNNAll adjuvants to local anesthetics were not created equal: animal data evaluating neurotoxicity, thermal hyperalgesia, and relevance to human applicationReg Anesth Pain Med201136321121221508791
PubMed Web of Science ®Google Scholar
KirkseyMAHaskinsSCChengJLiuSSLocal anesthetic peripheral nerve block adjuvants for prolongation of analgesia: a systematic qualitative reviewPloS One2015109e013731226355598
PubMed Web of Science ®Google Scholar
ArulkumarSElnagarIHamiltonCFoxCDexamethasone as an adjunct for brachial plexus blockade: meta-analysis2014 Available from: http://www.lsuhscshreveport.edu/Assets/uploads/LSUHealthShreveport/Documents/Anesthesiology/Posters/DexamethasoneRegionalAnesthesiaIARS2014.pdfAccessed June 13, 2017
Google Scholar
HuynhTMMarretEBonnetFCombination of dexamethasone and local anaesthetic solution in peripheral nerve blocks: A meta-analysis of randomised controlled trialsEur J Anaesthesiol2015321175175825774458
PubMed Web of Science ®Google Scholar
ChoiSRodsethRMcCartneyCJEffects of dexamethasone as a local anaesthetic adjuvant for brachial plexus block: a systematic review and meta-analysis of randomized trialsBr J Anaesth2014112342743924413428
PubMed Web of Science ®Google Scholar
De OliveiraGSJrAlmeidaMDBenzonHTMcCarthyRJPerioperative single dose systemic dexamethasone for postoperative pain: a meta-analysis of randomized controlled trialsAnesthesiology2011115357558821799397
PubMed Web of Science ®Google Scholar
LeeSChoiSIntravenous and perineural dexamethasone in peripheral nerve block: are they truly equivalent?Anesth Analg20151211251
Web of Science ®Google Scholar
SondekoppamRVUppalVGanapathySIntravenous or perineural dexamethasone for interscalene brachial plexus block: the equivalence not yet provenBr J Anaesth20141121175176
Web of Science ®Google Scholar
TigheSQPerineural or intravenous dexamethasone: do we still need catheters?Anaesthesia201671898398427396259
PubMed Web of Science ®Google Scholar
BolinEDWilsonSPerineural versus systemic dexamethasone: questions remain unansweredReg Anesth Pain Med201540439339426079360
PubMed Web of Science ®Google Scholar
AlbrechtEKernCKirkhamKRPerineural vs intravenous administration of dexamethasone: more data are availableBr J Anaesth20151141160
Web of Science ®Google Scholar
HozoSPDjulbegovicBHozoIEstimating the mean and variance from the median, range, and the size of a sampleBMC Med Res Methodol200551315840177
PubMedGoogle Scholar
AbdelmonemARizkSNComparative study between intravenous and local dexamethasone as adjuvant to bupivacaine in perianal blockEgypt J Anaesth2011273163168
Google Scholar
DesmetMBraemsHReynvoetMI.V. and perineural dexamethasone are equivalent in increasing the analgesic duration of a single-shot interscalene block with ropivacaine for shoulder surgery: a prospective, randomized, placebo-controlled studyBr J Anaesth2013111344545223587875
PubMed Web of Science ®Google Scholar
KawanishiRYamamotoKTobettoYPerineural but not systemic low-dose dexamethasone prolongs the duration of interscalene block with ropivacaine: a prospective randomized trialLocal Reg Anesth201475924817819
PubMedGoogle Scholar
RahangdaleRKendallMCMcCarthyRJThe effects of perineural versus intravenous dexamethasone on sciatic nerve blockade outcomes: a randomized, double-blind, placebo-controlled studyAnesth Analg201411851113111924686045
PubMed Web of Science ®Google Scholar
AbdallahFWJohnsonJChanVIntravenous dexamethasone and perineural dexamethasone similarly prolong the duration of analgesia after supraclavicular brachial plexus block: a randomized, triple-arm, double-blind, placebo-controlled trialReg Anesth Pain Med201540212513225629321
PubMed Web of Science ®Google Scholar
ChunEHKimYJWooJHWhich is your choice for prolonging the analgesic duration of single-shot interscalene brachial blocks for arthroscopic shoulder surgery? Intravenous dexamethasone 5 mg vs. perineural dexamethasone 5 mg randomized, controlled, clinical trialMedicine (Baltimore)20169523e382827281084
PubMed Web of Science ®Google Scholar
DawsonRLMcLeodDHKoerberJPPlummerJLDracopoulosGCA randomised controlled trial of perineural vs intravenous dexamethasone for foot surgeryAnaesthesia201671328529026682721
PubMed Web of Science ®Google Scholar
LeurcharusmeePAlisteJVan ZundertTCA multicenter randomized comparison between intravenous and perineural dexamethasone for ultrasound-guided infraclavicular blockReg Anesth Pain Med201641332833327015546
PubMed Web of Science ®Google Scholar
RosenfeldDMIvancicMGHattrupSJPerineural versus intravenous dexamethasone as adjuncts to local anaesthetic brachial plexus block for shoulder surgeryAnaesthesia201671438038826899862
PubMed Web of Science ®Google Scholar
AlisteJLeurcharusmeePEngsusophonPA randomized comparison between intravenous and perineural dexamethasone for ultrasound-guided axillary blockCan J Anaesth2017641293627663451
PubMed Web of Science ®Google Scholar
Morales-MuñozCSánchez-RamosJLDiaz-LaraMDGonzález-GonzálezJGallego-AlonsoIHernández-del-CastilloMSAnalgesic effect of a single-dose of perineural dexamethasone on ultrasound-guided femoral nerve block after total knee replacementRev Esp Anestesiol Reanim2017641192627372380
PubMed Web of Science ®Google Scholar
RückerGCarpenterJRSchwarzerGDetecting and adjusting for small-study effects in meta-analysisBiom J201153235136821374698
PubMed Web of Science ®Google Scholar
NiemiGBreivikHAdrenaline markedly improves thoracic epidural analgesia produced by a low-dose infusion of bupivacaine, fentanyl and adrenaline after major surgery: a randomised, double-blind, crossover study with and without adrenalineActa Anaesthesiol Scand19984288979099773133
PubMed Web of Science ®Google Scholar
SakaguchiYSakuraSShinzawaMSaitoYDoes adrenaline improve epidural bupivacaine and fentanyl analgesia after abdominal surgery?Anaesth Intensive Care200028552252611094667
PubMed Web of Science ®Google Scholar
BoussofaraMCarlesMRaucoules-AimeMSellamMRHornJLEffects of intrathecal midazolam on postoperative analgesia when added to a bupivacaine-clonidine mixtureReg Anesth Pain Med200631650150517138191
PubMed Web of Science ®Google Scholar
KazemeiniARahimiMFazeliMSThe effect of local injections of bupivacaine plus ketamine, bupivacaine alone, and placebo on reducing postoperative anal fistula pain: a randomized clinical trialScientificWorldJournal2014201442415225544955
PubMedGoogle Scholar
TrifaMEngelhardtTKhalifaSBThe addition of clonidine to bupivacaine in saphenous/sciatic nerve blocks in childrenPaediatr Anaesth201626332132226814039
PubMed Web of Science ®Google Scholar
XiangQHuangDYZhaoYLCaudal dexmedetomidine combined with bupivacaine inhibit the response to hernial sac traction in children undergoing inguinal hernia repairBr J Anaesth2013110342042423161357
PubMed Web of Science ®Google Scholar
MartinezVFletcherDDexamethasone and peripheral nerve blocks: on the nerve or intravenous?Br J Anaesth2014113333834024907282
PubMed Web of Science ®Google Scholar
Yilmaz-RastoderEGoldMSHoughKAGebhartGFWilliamsBAEffect of adjuvant drugs on the action of local anesthetics in isolated rat sciatic nervesReg Anesth Pain Med201237440340922430023
PubMed Web of Science ®Google Scholar
BuvanendranAKroinJSLiJMoricMTumanKJRelative contribution of adjuvants to local anesthetic for prolonging the duration of peripheral nerve blocks in ratsReg Anesth Pain Med201641558959227483415
PubMed Web of Science ®Google Scholar
AnKElkassabanyNMLiuJDexamethasone as adjuvant to bupivacaine prolongs the duration of thermal antinociception and prevents bupivacaine-induced rebound hyperalgesia via regional mechanism in a mouse sciatic nerve block modelPloS One2015104e012345925856078
PubMed Web of Science ®Google Scholar
BarnesPJAnti-inflammatory actions of glucocorticoids: molecular mechanismsClin Sci (Lond)19989465575729854452
PubMed Web of Science ®Google Scholar
WilliamsBAHoughKATsuiBYIbinsonJWGoldMSGebhartGFNeurotoxicity of adjuvants used in perineural anesthesia and analgesia in comparison with ropivacaineReg Anesth Pain Med201136322523021519308
PubMed Web of Science ®Google Scholar
WatkinsTWDupreSCoucherJRRopivacaine and dexamethasone: a potentially dangerous combination for therapeutic pain injectionsJ Med Imaging Radiat Oncol201559557157726076198
PubMed Web of Science ®Google Scholar
HwangHParkJLeeWKCrystallization of local anesthetics when mixed with corticosteroid solutionsAnn Rehabil Med2016401212726949665
PubMedGoogle Scholar
AwadKAhmedHAbushoukAIDexamethasone combined with other antiemetics versus single antiemetics for prevention of postoperative nausea and vomiting after laparoscopic cholecystectomy: an updated systematic review and meta-analysisInt J Surg201636Pt A15216327793640
PubMed Web of Science ®Google Scholar
AlbrechtEKernCKirkhamKRA systematic review and meta-analysis of perineural dexamethasone for peripheral nerve blocksAnaesthesia2015701718325123271
PubMed Web of Science ®Google Scholar

Share icon
Back to Top

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.

People also read
Recommended articles
Cited by

To cite this article:

Reference style: APA Chicago Harvard

Citation copied to clipboard

Reference styles above use APA (6th edition), Chicago (16th edition) & Harvard (10th edition)

Download citation

Download a citation file in RIS format that can be imported by citation management software including EndNote, ProCite, RefWorks and Reference Manager.

Choose format: RIS BibTex RefWorks Direct Export

Choose options: Citation Citation & abstract Citation & references

Perineural versus intravenous dexamethasone as an adjuvant in regional anesthesia: a systematic review and meta-analysis

References

References

Information for

Open access

Opportunities

Help and information

Your download is now in progress and you may close this window

Login or register to access this feature

Perineural versus intravenous dexamethasone as an adjuvant in regional anesthesia: a systematic review and meta-analysis

References

References

Related research

To cite this article:

Download citation

Information for

Open access

Opportunities

Help and information

Keep up to date