Ultrasound-Guided Nerve Hydrodissection for Pain Management: Rationale, Methods, Current Literature, and Theoretical Mechanisms

References

• Wu Y-T, Ho T-Y, Chou Y-C, et al. Six-month efficacy of perineural dextrose for carpal tunnel syndrome: a prospective, randomized, double-blind, controlled trial. Mayo Clin Proc. 2017;92(8):1179–1189. doi:10.1016/j.mayocp.2017.05.025
   PubMed Web of Science ®Google Scholar
• Wu YT, Ke MJ, Ho TY, Li TY, Shen YP, Chen LC. Randomized double-blinded clinical trial of 5% dextrose versus triamcinolone injection for carpal tunnel syndrome patients. Ann Neurol. 2018;84(4):601–610. doi:10.1002/ana.25332
   PubMed Web of Science ®Google Scholar
• Wu YT, Chen SR, Li TY, et al. Nerve hydrodissection for carpal tunnel syndrome: a prospective, randomized, double-blind, controlled trial. Muscle Nerve. 2019;59(2):174–180. doi:10.1002/mus.26358
   Web of Science ®Google Scholar
• Wu Y-T, Ho T-Y, Chou Y-C, et al. Six-month efficacy of platelet-rich plasma for carpal tunnel syndrome: a prospective randomized, single-blind controlled trial. Sci Rep. 2017;7(1):94. doi:10.1038/s41598-017-00224-6
   Web of Science ®Google Scholar
• Malone DGCTB, Wei N. Ultrasound-guided percutaneous injection, hydrodissection, and fenestration for carpal tunnel syndrome: description of a new technique. J Appl Res. 2010;10(3):107–114.
   Google Scholar
• McShane JM, Slaff S, Gold JE, Nazarian LN. Sonographically guided percutaneous needle release of the carpal tunnel for treatment of carpal tunnel syndrome: preliminary report. J Ultrasound Med. 2012;31(9):1341–1349. doi:10.7863/jum.2012.31.9.1341
   Web of Science ®Google Scholar
• Elawamy A, Hassanien M, Hamed A, et al. Efficacy of hyalase hydrodissection in the treatment of carpal tunnel syndrome: a randomized, double-blind, controlled, clinical trial. Pain Physician. 2020;23(2):E175–E183.
   Web of Science ®Google Scholar
• Shen YP, Li TY, Chou YC, et al. Comparison of perineural platelet-rich plasma and dextrose injections for moderate carpal tunnel syndrome: a prospective randomized, single-blind, head-to-head comparative trial. J Tissue Eng Regen Med. 2019;13(11):2009–2017. doi:10.1002/term.2950
   PubMed Web of Science ®Google Scholar
• Lam SKH, Reeves KD, Cheng AL. Transition from deep regional blocks toward deep nerve hydrodissection in the upper body and torso: method description and results from a retrospective chart review of the analgesic effect of 5% dextrose water as the primary hydrodissection injectate to enhance safety. Biomed Res Int. 2017;2017:7920438.
   PubMed Web of Science ®Google Scholar
• Cass SP. Ultrasound-guided nerve hydrodissection: what is it? A review of the literature. Curr Sports Med Rep. 2016;15(1):20–22. doi:10.1249/JSR.0000000000000226
   Web of Science ®Google Scholar
• Andreone BJ, Lacoste B, Gu C. Neuronal and vascular interactions. Annu Rev Neurosci. 2015;38(1):25–46. doi:10.1146/annurev-neuro-071714-033835
   PubMed Web of Science ®Google Scholar
• Bennett GJ, Xie YK. A peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in man. Pain. 1988;33(1):87–107. doi:10.1016/0304-3959(88)90209-6
   PubMed Web of Science ®Google Scholar
• Bennett GJCJ, Honore M, Seltzer Z. Models of neuropathic pain in the rat. Curr Protoc Neurosci. 2003;22(1):9–14.
   Google Scholar
• Finnerup NB, Haroutounian S, Kamerman P, et al. Neuropathic pain: an updated grading system for research and clinical practice. Pain. 2016;157(8):1599–1606. doi:10.1097/j.pain.0000000000000492
   PubMed Web of Science ®Google Scholar
• Treede RD, Jensen TS, Campbell JN, et al. Neuropathic pain: redefinition and a grading system for clinical and research purposes. Neurology. 2008;70(18):1630–1635. doi:10.1212/01.wnl.0000282763.29778.59
   PubMed Web of Science ®Google Scholar
• Bradshaw JM. Lecture on nerve-stretching for the relief or cure of pain. Br Med J. 1883;2(1198):1173–1179. doi:10.1136/bmj.2.1198.1173
   Google Scholar
• Sugar OVH. Victor Horsley, John Marshall, nerve stretching, and the nervi nervorum. Surg Neurol. 1990;34(3):184–187. doi:10.1016/0090-3019(90)90071-V
   Google Scholar
• Victor H. Preliminary communication on the existence of sensory nerves in nerve trunks. True “nervi nervorum”. Br Med J. 1884;1:166.
   Google Scholar
• Carrero G, Moon JK. Fascicular anatomy, nervi nervorum, and paresthesia. Reg Anesth Pain Med. 2003;1:72–73.
   Google Scholar
• Vilensky JAGS, Gilman S, Casey K. Sir Victor Horsley, Mr John Marshall, the nervi nervorum, and pain: more than a century ahead of their time. Arch Neurol. 2005;62(3):499–501. doi:10.1001/archneur.62.3.499
   Google Scholar
• Mizisin APWA, Weerasuriya A. Homeostatic regulation of the endoneurial microenvironment during development, aging and in response to trauma, disease and toxic insult. Acta Neuropathol. 2011;121(3):291–312. doi:10.1007/s00401-010-0783-x
   PubMed Web of Science ®Google Scholar
• Yali Jia TKB, Wang RK. Label-free 3D optical microangiography imaging of functional vasa nervorum and peripheral microvascular tree in the hind limb of diabetic mice. J Innov Opt Health Sci. 2010;13(4):307–313.
   Google Scholar
• Felten DLSMM. Peripheral Nervous System. Netter’s Atlas of Neuroscience (Third Edition). 2016:153–231. Elsevier.
   Google Scholar
• Kim JY, Song S, Park HJ, Rhee WI, Won SJ. Diagnostic cutoff value for ultrasonography of the common fibular neuropathy at the fibular head. Ann Rehabil Med. 2016;40(6):1057–1063. doi:10.5535/arm.2016.40.6.1057
   PubMedGoogle Scholar
• Bedewi MA, Abodonya A, Kotb M, et al. Estimation of ultrasound reference values for the lower limb peripheral nerves in adults: a cross-sectional study. Medicine. 2018;97(12):e0179. doi:10.1097/MD.0000000000010179
   Web of Science ®Google Scholar
• Lam SKH, Hung C-Y, Clark TB. Loss of the “Seesaw Sign” of the sciatic nerve in a marathon runner complaining of hamstring cramping. Pain Med. 2020;21(2):e247–e248. doi:10.1093/pm/pnz283
   Web of Science ®Google Scholar
• Soneji N, Peng PW. Ultrasound-guided pain interventions – a review of techniques for peripheral nerves. Korean J Pain. 2013;26(2):111–124. doi:10.3344/kjp.2013.26.2.111
   Google Scholar
• Misra S, Reed KB, Schafer BW, Ramesh KT, Okamura AM. Mechanics of flexible needles robotically steered through soft tissue. Int J Rob Res. 2010;29(13):1640–1660. doi:10.1177/0278364910369714
   PubMed Web of Science ®Google Scholar
• Jeng CL, Torrillo TM, Rosenblatt MA. Complications of peripheral nerve blocks. Br J Anaesth. 2010;105(Suppl 1):i97–107. doi:10.1093/bja/aeq273
   PubMed Web of Science ®Google Scholar
• Tran TA, Williams LM, Bui D, Anthonisen C, Poltavskiy E, Szabo RM. Prospective pilot study comparing pre- and postsurgical CTSAQ and neuro-QoL questionnaire with median nerve high-resolution ultrasound cross-sectional areas. J Hand Surg Am. 2018;43(2):184e181–184 e189. doi:10.1016/j.jhsa.2017.08.015
   Web of Science ®Google Scholar
• Raeissadat SA, Karimzadeh A, Hashemi M, Bagherzadeh L. Safety and efficacy of platelet-rich plasma in treatment of carpal tunnel syndrome; a randomized controlled trial. BMC Musculoskelet Disord. 2018;19(1):49. doi:10.1186/s12891-018-1963-4
   Web of Science ®Google Scholar
• Senna MK, Shaat RM, Ali AAA. Platelet-rich plasma in treatment of patients with idiopathic carpal tunnel syndrome. Clin Rheumatol. 2019;38(12):3643–3654. doi:10.1007/s10067-019-04719-7
   Web of Science ®Google Scholar
• Catapano MCJ, Borschel G, Alavinia SM, Robinson LR, Mittal N. Effectiveness of platelet-rich plasm injections for nonsurgical management of carpal tunnel syndrome: a systematic review and meta-analysis of randomized controlled trials. Arch Phys Med Rehabil. 2020;101:897–906. doi:10.1016/j.apmr.2019.10.193
   Web of Science ®Google Scholar
• Liza Maniquis-Smigel KDR, Rosen HJ, Lyftogt J, Graham-Coleman C, Cheng A-L, Rabago. D. Analgesic effect of caudal 5% dextrose in water in chronic low back pain. A randomized controlled trial of epidural injection. Anesth Pain Med. 2016.
   Google Scholar
• Maniquis-Smigel L, Reeves KD, Rosen HJ, et al. Analgesic effect and potential cumulative benefit from caudal epidural D5W in consecutive participants with chronic low-back and buttock/leg pain. J Altern Complement Med. 2018;24(12):1189–1196. doi:10.1089/acm.2018.0085
   PubMed Web of Science ®Google Scholar
• Malek N, Pajak A, Kolosowska N, Kucharczyk M, Starowicz K. The importance of TRPV1-sensitisation factors for the development of neuropathic pain. Mol Cell Neurosci. 2015;65(Mar):1–10. doi:10.1016/j.mcn.2015.02.001
   Web of Science ®Google Scholar
• Szolcsányi JLSZ, Sándor Z. Multisteric TRPV1 nocisensor: a target for analgesics. Trends Pharmacol Sci. 2012;33(12):646–655. doi:10.1016/j.tips.2012.09.002
   PubMed Web of Science ®Google Scholar
• Bertrand H, Kyriazis M, Reeves KD, Lyftogt J, Rabago D. Topical mannitol reduces capsaicin-induced pain: results of a pilot-level, double-blind, randomized controlled trial. PM R. 2015;7(11):1111–1117. doi:10.1016/j.pmrj.2015.05.002
   Google Scholar
• Fujita SBM, Bohland M, Watts G, Watts AG, Donovan CM. Hypoglycemic detection at the portal vein is mediated by capsaicin-sensitive primary sensory neurons. Am J Physiol Endocrinol Metab. 2007;293(1):96–101. doi:10.1152/ajpendo.00415.2006
   Web of Science ®Google Scholar
• MacIver MB, Tanelian DL. Activation of C fibers by metabolic perturbations associated with tourniquet ischemia. Anesthesiology. 1992;76(4):617–623. doi:10.1097/00000542-199204000-00020
   PubMed Web of Science ®Google Scholar
• Evers S, Thoreson AR, Smith J, Zhao C, Geske JR, Amadio PC. Ultrasound-guided hydrodissection decreases gliding resistance of the median nerve within the carpal tunnel. Muscle Nerve. 2018;57(1):25–32. doi:10.1002/mus.25723
   Web of Science ®Google Scholar