123
Views
0
CrossRef citations to date
0
Altmetric
ORIGINAL RESEARCH

Non Clinical Model to Assess the Mechanism of Action of a Combined Hyaluronic Acid, Chondroitin Sulfate and Calcium Chloride: HA+CS+CaCl2 Solution on a 3D Human Reconstructed Bladder Epithelium

, ORCID Icon & ORCID Icon
Pages 47-58 | Received 16 Sep 2023, Accepted 10 Jan 2024, Published online: 29 Jan 2024

References

  • Klein RD, Hultgren SJ. Urinary tract infections: microbial pathogenesis, host-pathogen interactions and new treatment strategies. Nat Rev Microbiol. 2020;18(4):211–226. doi:10.1038/s41579-020-0324-0
  • Foxman B, Brown P. Epidemiology of urinary tract infections: transmission and risk factors, incidence, and costs. Infect Dis Clin North Am. 2003;17(2):227–241. doi:10.1016/s0891-5520(03)00005-9
  • Hunstad DA, Justice SS, Hung CS, Lauer SR, Hultgren SJ. Suppression of bladder epithelial cytokine responses by uropathogenic Escherichia coli. Infect Immun. 2005;73(7):3999–4006. doi:10.1128/IAI.73.7.3999-4006.2005
  • Billips BK, Forrestal SG, Rycyk MT, Johnson JR, Klumpp DJ, Schaeffer AJ. Modulation of host innate immune response in the bladder by uropathogenic Escherichia coli. Infect Immun. 2007;75(11):5353–5360. doi:10.1128/IAI.00922-07
  • Billips BK, Schaeffer AJ, Klumpp DJ. Molecular basis of uropathogenic Escherichia coli evasion of the innate immune response in the bladder. Infect Immun. 2008;76(9):3891–3900. doi:10.1128/IAI.00069-08
  • Kaper JB, Nataro JP, Mobley HL. Pathogenic Escherichia coli. Nat Rev Microbiol. 2004;2(2):123–140. doi:10.1038/nrmicro818
  • Kudinha T The Pathogenesis of Escherichia coli Urinary Tract Infection [Internet]. Escherichia coli - Recent Advances on Physiology, Pathogenesis and Biotechnological Applications. InTech; 2017.
  • Mobley HL, Island MD, Massad G. Virulence determinants of uropathogenic Escherichia coli and Proteus mirabilis. Kidney Int Suppl. 1994;47:S129–S136.
  • Schilling JD, Lorenz RG, Hultgren SJ. Effect of trimethoprim-sulfamethoxazole on recurrent bacteriuria and bacterial persistence in mice infected with uropathogenic Escherichia coli. Infect Immun. 2002;70(12):7042–7049. doi:10.1128/IAI.70.12.7042-7049.2002
  • Rosen DA, Hooton TM, Stamm WE, Humphrey PA, Hultgren SJ. Detection of intracellular bacterial communities in human urinary tract infection. PLoS Med. 2007;4(12):e329. doi:10.1371/journal.pmed.0040329
  • Mulvey MA, Schilling JD, Hultgren SJ. Establishment of a persistent Escherichia coli reservoir during the acute phase of a bladder infection. Infect Immun. 2001;69(7):4572–4579. doi:10.1128/IAI.69.7.4572-4579.2001
  • Stærk K, Khandige S, Kolmos HJ, Møller-Jensen J, Andersen TE. Uropathogenic Escherichia coli express type 1 fimbriae only in surface adherent populations under physiological growth conditions. J Infect Dis. 2016;213(3):386–394. doi:10.1093/infdis/jiv422
  • Gupta K, Grigoryan L, Trautner B. Urinary tract infection. Ann Intern Med. 2017;167(7):ITC49–ITC64. doi:10.7326/AITC201710030
  • EAU Guidelines on Urological Infections. presented at the EAU annual congress Milan, Italy 2023; 2023.
  • Anger JT, Bixler BR, Holmes RS, Lee UJ, Santiago-Lastra Y, Selph SS. Updates to recurrent uncomplicated urinary tract infections in women: AUA/CUA/SUFU guideline. J Urol. 2022;208(3):536–541. doi:10.1097/JU.0000000000002860
  • Damiano R, Quarto G, Bava I, et al. Prevention of recurrent urinary tract infections by intravesical administration of hyaluronic acid and chondroitin sulphate: a placebo-controlled randomised trial [published correction appears in Eur Urol. 2011 Jul;60(1):193]. Eur Urol. 2011;59(4):645–651. doi:10.1016/j.eururo.2010.12.039
  • De Vita D, Giordano S. Effectiveness of intravesical hyaluronic acid/chondroitin sulfate in recurrent bacterial cystitis: a randomized study. Int Urogynecol J. 2012;23(12):1707–1713. doi:10.1007/s00192-012-1794-z
  • Goddard JC, Janssen DAW. Intravesical hyaluronic acid and chondroitin sulfate for recurrent urinary tract infections: systematic review and meta-analysis. Int Urogynecol J. 2018;29(7):933–942. doi:10.1007/s00192-017-3508-z
  • Wiles TJ, Kulesus RR, Mulvey MA. Origins and virulence mechanisms of uropathogenic Escherichia coli. Exp Mol Pathol. 2008;85(1):11–19. doi:10.1016/j.yexmp.2008.03.007
  • Hilbert DW, Pascal KE, Libby EK, Mordechai E, Adelson ME, Trama JP. Uropathogenic Escherichia coli dominantly suppress the innate immune response of bladder epithelial cells by a lipopolysaccharide- and Toll-like receptor 4-independent pathway. Microbes Infect. 2008;10(2):114–121. doi:10.1016/j.micinf.2007.10.012
  • Maldonado-Barragán A, Mshana SE, Keenan K, et al. Predominance of multidrug-resistant (MDR) bacteria causing urinary tract infections (UTIs) among symptomatic patients in East Africa: a call for action. medRxiv. 2023. doi:10.1101/2023.06.13.23291274
  • Penn R, Ward BJ, Strande L, Maurer M. Review of synthetic human faeces and faecal sludge for sanitation and wastewater research. Water Res. 2018;132:222–240.
  • Casiraghi A, Ranzini F, Musazzi UM, Franzè S, Meloni M, Minghetti P. In vitro method to evaluate the barrier properties of medical devices for cutaneous use. Regul Toxicol Pharmacol. 2017;90:42–50. doi:10.1016/j.yrtph.2017.08.007
  • Gordon S, Daneshian M, Bouwstra J, et al. Non-animal models of epithelial barriers (skin, intestine and lung) in research, industrial applications and regulatory toxicology. ALTEX. 2015;32(4):327–378. doi:10.14573/altex.1510051
  • Ayehunie S, Wang YY, Landry T, Bogojevic S, Cone RA. Hyperosmolal vaginal lubricants markedly reduce epithelial barrier properties in a three-dimensional vaginal epithelium model [published correction appears in Toxicol Rep. 2020 Dec 25;8:62–63]. Toxicol Rep. 2017;(5):134–140. doi:10.1016/j.toxrep.2017.12.011
  • De Jong WH, Hoffmann S, Lee M, et al. Round robin study to evaluate the reconstructed human epidermis (RhE) model as an in vitro skin irritation test for detection of irritant activity in medical device extracts. Toxicol In Vitro. 2018;50:439–449. doi:10.1016/j.tiv.2018.01.001
  • Meloni M, Balzaretti S, Ceriotti L. Medical devices biocompatibility assessment on HCE: evidences of delayed cytotoxicity of preserved compared to preservative free eye drops. Regul Toxicol Pharmacol. 2019;106:81–89. doi:10.1016/j.yrtph.2019.04.022
  • Sica VP, Friberg MA, Teufel AG, et al. Safety assessment scheme for menstrual cups and application for the evaluation of a menstrual cup comprised of medical grade silicone. EBioMedicine. 2022;86:104339. doi:10.1016/j.ebiom.2022.104339
  • Cárdenas-Calderón C, Veloso-Giménez V, González T, et al. Development of an implantable three-dimensional model of a functional pathogenic multispecies biofilm to study infected wounds. Sci Rep. 2022;12(1):21846. doi:10.1038/s41598-022-25569-5
  • De Servi B, Ranzini F. Protective efficacy of antidiarrheal agents in a permeability model of Escherichia coli-infected CacoGoblet® cells. Future Microbiol. 2017;12:1449–1455. doi:10.2217/fmb-2016-0195