Nutritional supplementation to prevent and slow the progression of chronic kidney disease: focus on bicarbonate

References

• Mitch WE. Metabolic and clinical consequences of metabolic acidosis. J Nephrol. 2006;19 Suppl 9:S70–S75.
   Google Scholar
• Kraut JA, Coburn JW Bone, acid, and osteoporosis. N Engl J Med. 1994;330(25):1821–1822.
   Web of Science ®Google Scholar
• Kraut JA, Mishler DR, Singer FR, Goodman WG. The effects of metabolic acidosis on bone formation and bone resorption in the rat. Kidney Int. 1986;30(5):694–700.
   Web of Science ®Google Scholar
• Mitch WE. Robert H Herman Memorial Award in Clinical Nutrition Lecture, 1997. Mechanisms causing loss of lean body mass in kidney disease. Am J Clin Nutr. 1998;67(3):359–366.
   Google Scholar
• Weisbord SD, Mor MK, Resnick AL, et al. Prevention, incidence, and outcomes of contrast-induced acute kidney injury. Arch Intern Med. 2008;168(12):1325–1332.
   PubMedGoogle Scholar
• McCullough PA, Adam A, Becker CR, et al. Epidemiology and prognostic implications of contrast-induced nephropathy. Am J Cardiol. 2006;98(6A):5K–13K.
   PubMed Web of Science ®Google Scholar
• McCullough PA, Adam A, Becker CR, et al. Risk prediction of contrast-induced nephropathy. Am J Cardiol. 2006;98(6A):27K–36K.
   PubMed Web of Science ®Google Scholar
• McCullough PA, Stacul F, Becker CR, et al. Contrast-Induced Nephropathy (CIN) Consensus Working Panel: executive summary. Rev Cardiovasc Med. 2006;7(4):177–197.
   PubMed Web of Science ®Google Scholar
• Coresh J, Selvin E, Stevens LA, et al. Prevalence of chronic kidney disease in the United States. JAMA. 2007;298(17):2038–2047.
   PubMed Web of Science ®Google Scholar
• Gumz ML, Lynch IJ, Greenlee MM, Cain BD, Wingo CS. The renal H+-K+-ATPases: physiology, regulation, and structure. Am J Physiol Renal Physiol. 2010;298(1):F12–F21.
   PubMed Web of Science ®Google Scholar
• Snyder JJ, Foley RN, Collins AJ. Prevalence of CKD in the United States: a sensitivity analysis using the National Health and Nutrition Examination Survey (NHANES) 1999–2004. Am J Kidney Dis. 2009;53(2):218–228.
   PubMed Web of Science ®Google Scholar
• Thilly N, Boini S, Kessler M, Briancon S, Frimat L. Chronic kidney disease: appropriateness of therapeutic management and associated factors in the AVENIR study. JEval Clin Pract. 2009;15(1):121–128.
   Google Scholar
• Kalantar-Zadeh K, Mehrotra R, Fouque D, Kopple JD. Metabolic acidosis and malnutrition-inflammation complex syndrome in chronic renal failure. Semin Dial. 2004;17(6):455–65.
   PubMed Web of Science ®Google Scholar
• Tizianello A, De Ferrari G, Garibotto G, Gurreri G, Robaudo C. Renal metabolism of amino acids and ammonia in subjects with normal renal function and in patients with chronic renal insufficiency. J Clin Invest. 1980;65(5):1162–1173.
   PubMed Web of Science ®Google Scholar
• Dass PD, Kurtz I. Renal ammonia and bicarbonate production in chronic renal failure. Miner Electrolyte Metab. 1990;16(5):308–314.
   Google Scholar
• Goodman AD, Lemann J Jr, Lennon EJ, Relman AS. Production, excretion, and net balance of fixed acid in patients with renal acidosis. J Clin Invest. 1965;44:495–506.
   PubMed Web of Science ®Google Scholar
• Schwartz WB, Hall PW, III, Hays RM, Relman AS. On the mechanism of acidosis in chronic renal disease. J Clin Invest. 1959;38(1 Pt 1):39–52.
   Web of Science ®Google Scholar
• Kraut JA, Kurtz I. Metabolic acidosis of CKD: diagnosis, clinical characteristics, and treatment. Am J Kidney Dis. 2005;45(6):978–993.
   PubMed Web of Science ®Google Scholar
• Verove C, Maisonneuve N, El Azouzi A, Boldron A, Azar R. Effect of the correction of metabolic acidosis on nutritional status in elderly patients with chronic renal failure. J Ren Nutr. 2002;12(4):224–228.
   Web of Science ®Google Scholar
• Ballmer PE, McNurlan MA, Hulter HN, Anderson SE, Garlick PJ, Krapf R. Chronic metabolic acidosis decreases albumin synthesis and induces negative nitrogen balance in humans. J Clin Invest. 1995;95(1):39–45.
   Web of Science ®Google Scholar
• Mitch WE, Du J, Bailey JL, Price SR. Mechanisms causing muscle proteolysis in uremia: the influence of insulin and cytokines. Miner Electrolyte Metab. 1999;25(4–6):216–219.
   Google Scholar
• Lofberg E, Wernerman J, Anderstam B, Bergstrom J. Correction of acidosis in dialysis patients increases branched-chain and total essential amino acid levels in muscle. Clin Nephrol. 1997;48(4):230–237.
   Web of Science ®Google Scholar
• Bailey JL, Wang X, England BK, Price SR, Ding X, Mitch WE. The acidosis of chronic renal failure activates muscle proteolysis in rats by augmenting transcription of genes encoding proteins of the ATP- dependent ubiquitin-proteasome pathway. J Clin Invest. 1996;97(6): 1447–1453.
   PubMed Web of Science ®Google Scholar
• May RC, Kelly RA, Mitch WE. Mechanisms for defects in muscle protein metabolism in rats with chronic uremia. Influence of metabolic acidosis. J Clin Invest. 1987;79(4):1099–1103.
   Web of Science ®Google Scholar
• Leal VO, Delgado AG, Leite M Jr, Mitch WE, Mafra D. Influence of renal function and diet on acid-base status in chronic kidney disease patients. J Ren Nutr. 2009;19(2):178–182.
   Web of Science ®Google Scholar
• Clase CM, Kiberd BA, Garg AX. Relationship between glomerular filtration rate and the prevalence of metabolic abnormalities: results from the Third National Health and Nutrition Examination Survey (NHANES III). Nephron Clin Pract. 2007;105(4):c178–c184.
   PubMedGoogle Scholar
• Movilli E, Bossini N, Viola BF, et al. Evidence for an independent role of metabolic acidosis on nutritional status in haemodialysis patients. Nephrol Dial Transplant. 1998;13(3):674–678.
   Web of Science ®Google Scholar
• Eustace JA, Astor B, Muntner PM, Ikizler TA, Coresh J. Prevalence of acidosis and inflammation and their association with low serum albumin in chronic kidney disease. Kidney Int. 2004;65(3):1031–1040.
   Web of Science ®Google Scholar
• Krieger NS, Sessler NE, Bushinsky DA. Acidosis inhibits osteoblastic and stimulates osteoclastic activity in vitro. Am J Physiol. 1992;262 (3 Pt 2):F442–F448.
   PubMedGoogle Scholar
• Coe FL, Firpo JJ Jr, Hollandsworth DL, Segil L, Canterbury JM, Reiss E. Effect of acute and chronic metabolic acidosis on serum immunore- active parathyroid hormone in man. Kidney Int. 1975;8(4):263–273.
   Web of Science ®Google Scholar
• Kraut JA. Disturbances of acid-base balance and bone disease in endstage renal disease. Semin Dial. 2000;13(4):261–266.
   Web of Science ®Google Scholar
• Lemann J Jr, Bushinsky DA, Hamm LL. Bone buffering of acid and base in humans. Am J Physiol Renal Physiol. 2003;285(5):F811–F832.
   PubMed Web of Science ®Google Scholar
• Martin KJ, Freitag JJ, Bellorin-Font E, Conrades MB, Klahr S, Slato- polsky E. The effect of acute acidosis on the uptake of parathyroid hormone and the production of adenosine 3’,5’-monophosphate by isolated perfused bone. Endocrinology. 1980;106(5): 1607–1611.
   Web of Science ®Google Scholar
• Gadola L, Noboa O, Marquez MN, et al. Calcium citrate ameliorates the progression of chronic renal injury. Kidney Int. 2004;65(4): 1224–1230.
   Web of Science ®Google Scholar
• Nath KA, Hostetter MK, Hostetter TH. Pathophysiology of chronic tubulo-interstitial disease in rats. Interactions of dietary acid load, ammonia, and complement component C3. J Clin Invest. 1985;76(2): 667–675.
   Web of Science ®Google Scholar
• Torres VE, Cowley BD Jr, Branden MG, Yoshida I, Gattone VH. Long-term ammonium chloride or sodium bicarbonate treatment in two models of polycystic kidney disease. Exp Nephrol. 2001; 9(3): 171–180.
   Google Scholar
• Halperin ML, Ethier JH, Kamel KS. Ammonium excretion in chronic metabolic acidosis: benefits and risks. Am J Kidney Dis. 1989;14(4): 267–271.
   Web of Science ®Google Scholar
• Gennari FJ, Hood VL, Greene T, Wang X, Levey AS. Effect of dietary protein intake on serum total CO2 concentration in chronic kidney disease: Modification of Diet in Renal Disease study findings. Clin J Am Soc Nephrol. 2006;1(1):52–57.
   Web of Science ®Google Scholar
• Mehrotra R, Kopple JD. Protein and energy nutrition among adult patients treated with chronic peritoneal dialysis. Adv Ren Replace Ther. 2003;10(3):194–212.
   Google Scholar
• Bellocq A, Suberville S, Philippe C, et al. Low environmental pH is responsible for the induction of nitric-oxide synthase in macrophages. Evidence for involvement of nuclear factor-kappaB activation. J Biol Chem. 1998;273(9):5086–5092.
   Web of Science ®Google Scholar
• Pitt B, Zannad F, Remme WJ, et al. The effect of spironolactone on morbidity and mortality in patients with severe heart failure. Randomized Aldactone Evaluation Study Investigators. N Engl J Med. 1999; 341(10):709–717.
   PubMed Web of Science ®Google Scholar
• Thatte HS, Rhee JH, Zagarins SE, et al. Acidosis-induced apoptosis in human and porcine heart. Ann Thorac Surg. 2004;77(4):1376–1383.
   Web of Science ®Google Scholar
• Whittaker J, Cuthbert C, Hammond V, Alberti KG. Impaired insulin binding to isolated adipocytes in experimental diabetic ketoacidosis. Diabetologia. 1981;21(6):563–568.
   Web of Science ®Google Scholar
• Brungger M, Hulter HN, Krapf R. Effect of chronic metabolic acidosis on thyroid hormone homeostasis in humans. Am J Physiol. 1997;272 (5 Pt 2):F648–F653.
   Google Scholar
• Bommer J, Locatelli F, Satayathum S, et al. Association of predialysis serum bicarbonate levels with risk of mortality and hospitalization in the Dialysis Outcomes and Practice Patterns Study (DOPPS). Am J Kidney Dis. 2004;44(4):661–671.
   PubMed Web of Science ®Google Scholar
• Kovesdy CP, Anderson JE, Kalantar-Zadeh K. Association of serum bicarbonate levels with mortality in patients with non-dialysis-dependent CKD. Nephrol Dial Transplant. 2009;24(4):1232–1237.
   PubMed Web of Science ®Google Scholar
• Rustom R, Grime JS, Costigan M, et al. Oral sodium bicarbonate reduces proximal renal tubular peptide catabolism, ammoniogenesis, and tubular damage in renal patients. Ren Fail. 1998;20(2):371–382.
   PubMed Web of Science ®Google Scholar
• Mathur RP Dash SC, Gupta N, Prakash S, Saxena S, Bhowmik D. Effects of correction of metabolic acidosis on blood urea and bone metabolism in patients with mild to moderate chronic kidney disease: a prospective randomized single blind controlled trial. Ren Fail. 2006;28(1):1–5.
   PubMed Web of Science ®Google Scholar
• McSherry E, Morris RC Jr. Attainment and maintenance of normal stature with alkali therapy in infants and children with classic renal tubular acidosis. J Clin Invest. 1978;61(2):509–527.
   PubMed Web of Science ®Google Scholar
• Domrongkitchaiporn S, Pongskul C, Sirikulchayanonta V et al. Bone histology and bone mineral density after correction of acidosis in distal renal tubular acidosis. Kidney Int. 2002;62(6):2160–2166.
   Google Scholar
• de Brito-Ashurst I, Varagunam M, Raftery MJ, Yaqoob MM. Bicarbonate supplementation slows progression of CKD and improves nutritional status. J Am Soc Nephrol. 2009;20(9):2075–2084.
   PubMed Web of Science ®Google Scholar
• Roderick P, Willis NS, Blakeley S, Jones C, Tomson C. Correction of chronic metabolic acidosis for chronic kidney disease patients. Cochrane Database Syst Rev. 2007(1):CD001890.
   Google Scholar
• Szeto CC, Wong TY, Chow KM, Leung CB, Li PK. Oral sodium bicarbonate for the treatment of metabolic acidosis in peritoneal dialysis patients: a randomized placebo-control trial. J Am Soc Nephrol. 2003;14(8):2119–2126.
   PubMedGoogle Scholar
• KDOQI. National Kidney Foundation. Clinical practice guidelines for nutrition in chronic kidney disease. 2000; http://www.kidney.org/professionals/kdoqi/pdf/KDOQI2000NutritionGL.pdf. Accessed Apr 1, 2010.
   Google Scholar
• UKRA. Renal Association. Treatment of adults and children with renal failure: standards and audit measures. 2009; http://www.renal.org/Clinical/GuidelinesSection/Haemodialysis.aspx. Accessed Apr 1, 2010.
   Google Scholar
• Gabutti L, Ferrari N, Giudici G, Mombelli G, Marone C. Unexpected haemodynamic instability associated with standard bicarbonate hae- modialysis. Nephrol Dial Transplant. 2003;18(11):2369–2376.
   Google Scholar
• Stein A, Moorhouse J, Iles-Smith H, et al. Role of an improvement in acid-base status and nutrition in CAPD patients. Kidney Int. 1997; 52(4):1089–1095.
   Google Scholar
• Movilli E, Zani R, Carli O, et al. Correction of metabolic acidosis increases serum albumin concentrations and decreases kinetically evaluated protein intake in haemodialysis patients: a prospective study. Nephrol Dial Transplant. 1998;13(7):1719–1722.
   Google Scholar
• Graham KA, Reaich D, Channon SM, et al. Correction of acidosis in CAPD decreases whole body protein degradation. Kidney Int. 1996; 49(5):1396–1400.
   Google Scholar
• Kooman JP, Deutz NE, Zijlmans P, et al. The influence of bicarbonate supplementation on plasma levels of branched-chain amino acids in haemodialysis patients with metabolic acidosis. Nephrol Dial Transplant. 1997;12(11):2397–2401.
   Web of Science ®Google Scholar
• Lefebvre A, de Vernejoul MC, Gueris J, Goldfarb B, Graulet AM, Morieux C. Optimal correction of acidosis changes progression of dialysis osteodystrophy. Kidney Int. 1989;36(6):1112–1118.
   Google Scholar
• Pickering WP, Price SR, Bircher G, Marinovic AC, Mitch WE, Walls J. Nutrition in CAPD: serum bicarbonate and the ubiquitin-proteasome system in muscle. Kidney Int. 2002;61(4):1286–1292.
   Web of Science ®Google Scholar
• Mehran R, Aymong ED, Nikolsky E, et al. A simple risk score for prediction of contrast-induced nephropathy after percutaneous coronary intervention: development and initial validation. J Am Coll Cardiol. 2004;44(7):1393–1399.
   PubMed Web of Science ®Google Scholar
• Weisbord SD, Chen H, Stone RA, et al. Associations of increases in serum creatinine with mortality and length of hospital stay after coronary angiography. J Am Soc Nephrol. 2006;17(10):2871–2877.
   PubMed Web of Science ®Google Scholar
• Russo D, Minutolo R, Cianciaruso B, Memoli B, Conte G, De Nicola L. Early effects of contrast media on renal hemodynamics and tubular function in chronic renal failure. J Am Soc Nephrol. 1995;6(5): 1451–1458.
   PubMed Web of Science ®Google Scholar
• Katholi RE, Woods WT Jr, Taylor GJ, et al. Oxygen free radicals and contrast nephropathy. Am J Kidney Dis. 1998;32(1):64–71.
   PubMed Web of Science ®Google Scholar
• Bakris GL, Burnett JC Jr. A role for calcium in radiocontrast- induced reductions in renal hemodynamics. Kidney Int. 1985;27(2): 465–468.
   PubMed Web of Science ®Google Scholar
• Fujisaki K, Kubo M, Masuda K, et al. Infusion of radiocontrast agents induces exaggerated release of urinary endothelin in patients with impaired renal function. Clin Exp Nephrol. 2003;7(4):279–283.
   Google Scholar
• Locatelli F, Canaud B, Eckardt KU, Stenvinkel P, Wanner C, Zoc- cali C. Oxidative stress in end-stage renal disease: an emerging threat to patient outcome. Nephrol Dial Transplant. 2003;18(7): 1272–1280.
   PubMed Web of Science ®Google Scholar
• Massy ZA, Nguyen-Khoa T. Oxidative stress and chronic renal failure: markers and management. J Nephrol. 2002;15(4):336–341.
   Google Scholar
• Spargias K, Adreanides E, Demerouti E, et al. Iloprost prevents contrast-induced nephropathy in patients with renal dysfunction undergoing coronary angiography or intervention. Circulation. 2009; 120(18):1793–1799.
   Google Scholar
• Merten GJ, Burgess WP, Gray LV, et al. Prevention of contrast-induced nephropathy with sodium bicarbonate: a randomized controlled trial. JAMA. 2004;291(19):2328–2334.
   PubMed Web of Science ®Google Scholar
• Tumlin JA, Wang A, Murray PT, Mathur VS. Fenoldopam mesylate blocks reductions in renal plasma flow after radiocontrast dye infusion: a pilot trial in the prevention of contrast nephropathy. Am Heart J. 2002;143(5):894–903.
   PubMed Web of Science ®Google Scholar
• Caulfield JL, Singh SP, Wishnok JS, Deen WM, Tannenbaum SR. Bicarbonate inhibits N-nitrosation in oxygenated nitric oxide solutions. J Biol Chem. 1996;271(42):25859–25863.
   Google Scholar
• Brar SS, Shen AY, Jorgensen MB, et al. Sodium bicarbonate vs sodium chloride for the prevention of contrast medium-induced nephropathy in patients undergoing coronary angiography: a randomized trial. JAMA. 2008;300(9):1038–1046.
   PubMed Web of Science ®Google Scholar
• Maioli M, Toso A, Leoncini M, et al. Sodium bicarbonate versus saline for the prevention of contrast-induced nephropathy in patients with renal dysfunction undergoing coronary angiography or intervention. J Am Coll Cardiol. 2008;52(8):599–604.
   PubMed Web of Science ®Google Scholar
• Shaikh F, Maddikunta R, Museitif R, et al. A prospective randomized trial comparing normal saline and sodium bicarbonate with or without N-acetyleysteine for prevention of contrast-induced nephropathy. Am J Cardiol 2007;100(8):122L–123L Suppl 121; abstract.
   Google Scholar
• Kim Y-H. Preventive strategies of renal insufficiency in patients with diabetes undergoing intervention or arteriography. Paper presented at: American College of Cardiology Scientific Sessions; March, 2010; Atlanta, GA.
   Google Scholar
• Freiman JA, Chalmers TC, Smith H Jr, Kuebler RR. The importance of beta, the type II error and sample size in the design and interpretation of the randomized control trial. Survey of 71 “negative” trials. N Engl J Med. 1978;299(13):690–694.
   PubMed Web of Science ®Google Scholar
• Halpern SD, Karlawish JH, Berlin JA. The continuing unethical conduct of underpowered clinical trials. JAMA. 2002;288(3):358–362.
   PubMed Web of Science ®Google Scholar
• Masuda M, Yamada T, Mine T, et al. Comparison of usefulness of sodium bicarbonate versus sodium chloride to prevent contrast-induced nephropathy in patients undergoing an emergent coronary procedure. Am J Cardiol. 2007;100(5):781–786.
   Google Scholar
• Briguori C, Airoldi F, D’Andrea D, et al. Renal Insufficiency Following Contrast Media Administration Trial (REMEDIAL): a randomized comparison of 3 preventive strategies. Circulation. 2007;115(10):1211–1217.
   PubMed Web of Science ®Google Scholar
• Ozcan EE, Guneri S, Akdeniz B, et al. Sodium bicarbonate, N-acetylcysteine, and saline for prevention of radiocontrast-induced nephropathy. A comparison of 3 regimens for protecting contrast-induced nephropathy in patients undergoing coronary procedures. A single-center prospective controlled trial. Am Heart J. 2007;154(3):539–544.
   PubMed Web of Science ®Google Scholar
• Adolph E, Holdt-Lehmann B, Chatterjee T, et al. Renal Insufficiency Following Radiocontrast Exposure Trial (REINFORCE): a randomized comparison of sodium bicarbonate versus sodium chloride hydration for the prevention of contrast-induced nephropathy. Coron Artery Dis. 2008;19(6):413–419.
   PubMed Web of Science ®Google Scholar
• Brar SS, Hiremath S, Dangas G, Mehran R, Brar SK, Leon MB. Sodium bicarbonate for the prevention of contrast induced-acute kidney injury: a systematic review and meta-analysis. Clin J Am Soc Nephrol. 2009;4(10):1584–1592.
   Web of Science ®Google Scholar
• Zoungas S, Ninomiya T, Huxley R, et al. Systematic review: sodium bicarbonate treatment regimens for the prevention of contrast-induced nephropathy. Ann Intern Med. 2009;151(9):631–638.
   Google Scholar
• Kunadian V Zaman A, Spyridopoulos I, Qiu W. Sodium bicarbonate for the prevention of contrast induced nephropathy: a meta-analysis of published clinical trials. Eur J Radiol. Epub 2010 Jan 12.
   Google Scholar
• Hoste EA, De Waele JJ, Gevaert SA, Uchino S, Kellum JA. Sodium bicarbonate for prevention of contrast-induced acute kidney injury: a systematic review and meta-analysis. Nephrol Dial Transplant. 2010; 25(3):747–758.
   Google Scholar
• Meier P, Ko DT, Tamura A, Tamhane U, Gurm HS. Sodium bicarbonate- based hydration prevents contrast-induced nephropathy: a meta-analysis. BMC Med. 2009;7:23.
   PubMedGoogle Scholar
• Kanbay M, Covic A, Coca SG, Turgut F, Akcay A, Parikh CR. Sodium bicarbonate for the prevention of contrast-induced nephropathy: a meta-analysis of 17 randomized trials. Int Urol Nephrol. 2009; 41(3):617–627.
   Google Scholar
• Joannidis M, Schmid M, Wiedermann CJ. Prevention of contrast media- induced nephropathy by isotonic sodium bicarbonate: a meta-analysis. Wien Klin Wochenschr. 2008;120(23–24):742–748.
   Web of Science ®Google Scholar
• Navaneethan SD, Singh S, Appasamy S, Wing RE, Sehgal AR. Sodium bicarbonate therapy for prevention of contrast-induced nephropathy: a systematic review and meta-analysis. Am J Kidney Dis. 2009;53(4): 617–627.
   Web of Science ®Google Scholar
• Ho KM, Morgan DJ. Use of isotonic sodium bicarbonate to prevent radiocontrast nephropathy in patients with mild pre-existing renal impairment: a meta-analysis. Anaesth Intensive Care. 2008;36(5): 646–653.
   Web of Science ®Google Scholar
• Hogan SE, L’Allier P, Chetcuti S, et al. Current role of sodium bicarbonate-based preprocedural hydration for the prevention of contrast- induced acute kidney injury: a meta-analysis. Am Heart J. 2008; 156(3):414–421.
   Google Scholar
• Chen H, Wu H, He Q, Chen H, Mao Y. Comparison of sodium bicarbonate and sodium chloride as strategies for preventing contrast nephropathy. J Am Soc Nephrol. 2007;18:817A (abstract).
   Google Scholar
• Bagshaw SM, McAlister FA, Manns BJ, Ghali WA. Acetylcysteine in the prevention of contrast-induced nephropathy: a case study of the pitfalls in the evolution of evidence. Arch Intern Med. 2006;166(2): 161–166.
   PubMedGoogle Scholar
• Heguilen R, Liste A, Rosende G, et al. Prevention of contrast-induced nephropathy: volume expansion, N-acethylcysteine or both? Results from a pilot study. Nephrol Dial Transplant. 2007;22:vi54 (Suppl 56; abstract).
   Google Scholar
• Saidin R, Zainudin S, Norella CT, Maskon O, Saaidin NF, Shah Sa. Intravenous sodium bicarbonate versus normal saline infusion as prophylaxis against contrast nephropathy in patients with chronic kidney disease undergoing coronary angiography or angioplasty. J Am Soc Nephrol. 2006;17:766A (abstract).
   Google Scholar
• Vasheghani-Farahani A, Sadigh G, Kassaian SE, et al. Sodium bicarbonate plus isotonic saline versus saline for prevention of contrast-induced nephropathy in patients undergoing coronary angiography: a randomized controlled trial. Am J Kidney Dis. 2009; 54(4):610–618.
   Google Scholar
• Lin M, Sabeti M, Iskander E, Malhotra N, Pham PT, Pham PC. Prevention of contrast nephropathy with sodium bicarbonate. J Am Soc Nephrol. 2007;18:959A (abstract).
   Google Scholar
• Shavit L, Korenfeld R, Butnaru A, Slotki I. Sodium bicarbonate compared to sodium chloride and oral N-acetylcysteine for the prevention of contrast induced nephropathy in patients with advanced chronic kidney disease. J Am Soc Nephrol. 2008;19:787A (abstract).
   Google Scholar
• Kim G, Kim K, Shin J, Lee CH, Kang CM. Hydration with sodium bicarbonate for the prevention of radiocontrast-induced nephropathy. Nephrol Dial Transplant. 2007;22:vi49 (Suppl 46; abstract).
   Google Scholar