66
Views
7
CrossRef citations to date
0
Altmetric
Case Series

Varenicline improves motor and cognitive symptoms in early Huntington’s disease

, , , , &
Pages 2381-2386 | Published online: 19 Sep 2016

References

  • PhillipsWShannonKMBarkerRAThe current clinical management of Huntington’s diseaseMov Disord200823111491150418581443
  • YouSCGeschwindMDShaSJExecutive functions in premanifest Huntington’s diseaseMov Disord201429340540924375511
  • MontoyaAPriceBHMenearMLepageMBrain imaging and cognitive dysfunctions in Huntington’s diseaseJ Psychiatry Neurosci2006311212916496032
  • NovakMJTabriziSJHuntington’s disease: clinical presentation and treatmentInt Rev Neurobiol20119829732321907093
  • van DuijnEKingmaEMTimmanRCross-sectional study on prevalences of psychiatric disorders in mutation carriers of Huntington’s disease compared with mutation-negative first-degree relativesJ Clin Psychiatry200869111804181019026253
  • van DuijnEKingmaEMvan der MastRCPsychopathology in verified Huntington’s disease gene carriersJ Neuropsychiatry Clin Neurosci200719444144818070848
  • Van LiewCGluhmSGoldsteinJCronanTACorey-BloomJThe functional implications of motor, cognitive, psychiatric, and social problem-solving states in Huntington’s diseasePsychiatry201376432333524299091
  • ZanardiALeoGBiaginiGZoliMNicotine and neurodegeneration in ageingToxicol Lett20021271–320721512052660
  • PerryEKPerryRHSmithCJNicotinic receptor abnormalities in Alzheimer’s and Parkinson’s diseasesJ Neurol Neurosurg Psychiatry19875068068092956364
  • BatesGTabriziSJonesLHuntington’s Disease4th edOxford University PressOxford, UK2014
  • WaldvogelHJKimEHTippettLJVonsattelJPFaullRLThe neuropathology of Huntington’s diseaseCurr Top Behav Neurosci201522338025300927
  • SpokesEGNeurochemical alterations in Huntington’s chorea: a study of post-mortem brain tissueBrain198010311792106102490
  • LangeKWJavoy-AgidFAgidYJennerPMarsdenCDBrain muscarinic cholinergic receptors in Huntington’s diseaseJ Neurol199223921031041532417
  • FernandezHHFriedmanJHGraceJBeason-HazenSDonepezil for Huntington’s diseaseMov Disord200015117317610634264
  • RotUKobalJSeverAPirtosekZMesecARivastigmine in the treatment of Huntington’s diseaseEur J Neurol20029668969012453090
  • de TommasoMSpecchioNSciruicchioVDifruscoloOSpecchioLMEffects of rivastigmine on motor and cognitive impairment in Huntington’s diseaseMov Disord200419121516151815390067
  • CoeJWBrooksPRVetelinoMGVarenicline: an alpha4beta2 nicotinic receptor partial agonist for smoking cessationJ Med Chem200548103474347715887955
  • TonstadSRollemaHVarenicline in smoking cessationExpert Rev Respir Med20104329129920524911
  • ZesiewiczTASullivanKLTreatment of ataxia and imbalance with varenicline (chantix): report of 2 patients with spinocerebellar ataxia (types 3 and 14)Clin Neuropharmacol200831636336519050414
  • ZesiewiczTASullivanKLGoochCLLynchDRSubjective improvement in proprioception in 2 patients with atypical Friedreich ataxia treated with varenicline (Chantix)J Clin Neuromuscul Dis200910419119319494730
  • ZesiewiczTAGreensteinPESullivanKLA randomized trial of varenicline (Chantix) for the treatment of spinocerebellar ataxia type 3Neurology201278854555022323747
  • RollemaHGuanowskyVMineurYSVarenicline has antidepressant-like activity in the forced swim test and augments sertraline’s effectEur J Pharmacol20096051–311411619168054
  • ThomasKHMartinRMKnipeDWHigginsJPGunnellDRisk of neuropsychiatric adverse events associated with varenicline: systematic review and meta-analysisBMJ2015350h110925767129
  • ObachRSReed-HagenAEKruegerSSMetabolism and disposition of varenicline, a selective alpha4beta2 acetylcholine receptor partial agonist, in vivo and in vitroDrug Metab Dispos200634112113016221753
  • MihalakKBCarrollFILuetjeCWVarenicline is a partial agonist at alpha4beta2 and a full agonist at alpha7 neuronal nicotinic receptorsMol Pharmacol200670380180516766716
  • CiammolaASassoneJColciagoCAripiprazole in the treatment of Huntington’s disease: a case seriesNeuropsychiatr Dis Treat200951419557093
  • PaulRHLawrenceJWilliamsLMRichardCCCooperNGordonEPreliminary validity of “integneuro”: a new computerized battery of neurocognitive testsInt J Neurosci2005115111549156716223701
  • WilliamsLMSimmsEClarkCRPaulRHRoweDGordonEThe test-retest reliability of a standardized neurocognitive and neurophysiological test battery: “neuromarker”Int J Neurosci2005115121605163016287629
  • ClarkCRPaulRHWilliamsLMStandardized assessment of cognitive functioning during development and aging using an automated touchscreen batteryArch Clin Neuropsychol200621544946716904862
  • AndersonDJMalyszJGronlienJHStimulation of dopamine release by nicotinic acetylcholine receptor ligands in rat brain slices correlates with the profile of high, but not low, sensitivity alpha4beta2 subunit combinationBiochem Pharmacol200978784485119555668
  • EhretJCDayPSWiegandRWojcieszekJChambersRAHuntington disease as a dual diagnosis disorder: data from the national research roster for Huntington disease patients and familiesDrug Alcohol Depend2007862–328328616930866
  • BroseLSWestRStapletonJAComparison of the effectiveness of varenicline and combination nicotine replacement therapy for smoking cessation in clinical practiceMayo Clin Proc201388322623323489449
  • EbbertJOWyattKDHaysJTKleeEWHurtRDVarenicline for smoking cessation: efficacy, safety, and treatment recommendationsPatient Prefer Adherence2010435536221049087
  • RavvaPGastonguayMRFaesselHMLeeTCNiauraRPharmacokinetic-pharmacodynamic modeling of the effect of varenicline on nicotine craving in adult smokersNicotine Tob Res201517110611325145377
  • ZigmondASSnaithRPThe hospital anxiety and depression scaleActa Psychiatr Scand19836763613706880820
  • BoraEVelakoulisDWalterfangMSocial cognition in Huntington’s disease: a meta-analysisBehav Brain Res201629713114026455876
  • LofflerLARadkeSMorawetzCDerntlBEmotional dysfunctions in neurodegenerative diseasesJ Comp Neurol201652481727174326011035
  • BaezSHerreraEGershanikOImpairments in negative emotion recognition and empathy for pain in Huntington’s disease familiesNeuropsychologia20156815816725582408
  • SilversteinSMJaegerJDonovan-LeporeAMA comparative study of the MATRICS and IntegNeuro cognitive assessment batteriesJ Clin Exp Neuropsychol201032993795220455131
  • MasonSLZhangJBegetiFThe role of the amygdala during emotional processing in Huntington’s disease: from pre-manifest to late stage diseaseNeuropsychologia201570808925700742
  • WallaceTLBertrandDImportance of the nicotinic acetylcholine receptor system in the prefrontal cortexBiochem Pharmacol201385121713172023628449
  • LogueSFGouldTJThe neural and genetic basis of executive function: attention, cognitive flexibility, and response inhibitionPharmacol Biochem Behav2014123455423978501
  • NiemegeersPDumontGJQuisenaertsCThe effects of nicotine on cognition are dependent on baseline performanceEur Neuropsychopharmacol20142471015102324766971
  • LevinEDBradleyAAddyNSiguraniNHippocampal alpha 7 and alpha 4 beta 2 nicotinic receptors and working memoryNeuroscience2002109475776511927157
  • LevinEDalpha7-Nicotinic receptors and cognitionCurr Drug Targets201213560260622300026
  • QuikMZhangDPerezXABordiaTRole for the nicotinic cholinergic system in movement disorders; therapeutic implicationsPharmacol Ther20141441505924836728