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Review

Antianxiety medications for the treatment of complex agoraphobia: pharmacological interventions for a behavioral condition

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Pages 621-637 | Published online: 19 Oct 2011

References

  • MarksIMThe Agoraphobic Syndrome (Panic Disorder with Agoraphobia)Fears, Phobia and RitualNew YorkOxford University Press1987323361
  • American Psychiatric AssociationDiagnostic and Statistical Manual for Mental DisordersFourth Edition Text Revision (DSM-IV-TR)Washington, DCAmerican Psychiatric Association2000
  • World Health OrganizationICD-10, International Statistical Classification of Diseases and Related Health Problems10th edArlington, VAAmerican Psychiatry Publishing1992
  • KleinDFKleinHMThe utility of the panic disorder conceptEur Arch Psychiatry Neurol Sci19892385–62682792670574
  • BreierACharneyDSHeningerGRAgoraphobia with panic attacks: development, diagnostic stability, and course of illnessArch Gen Psychiatry19864311102910363767595
  • NoyesRThe natural history of anxiety disordersRothMNoyesRJrBarrowsGDHandbook of Anxiety: Biological, Clinical and Cultural Perspective1Amsterdam, The NetherlandsElsevier Science Publishers1988115133
  • WittchenHUNoconABeesdoKAgoraphobia and panic: prospective-longitudinal relations suggest a rethinking of diagnostic conceptsPsychother Psychosom200877314715718277061
  • FavaGARafanelliCTossaniEGrandiSAgoraphobia is a disease: a tribute to Sir Martin RothPsychother Psychosom200877313313818277059
  • FaravelliCCosciFRotellaFFaravelliLCatena Dell’ossoMAgoraphobia between panic and phobias: clinical epidemiology from the Sesto Fiorentino StudyCompr Psychiatry200849328328718396188
  • PernaGUnderstanding anxiety disorders: from psychology to psychopathology of defense mechanisms from threatRiv Psichiatr2011In press
  • WittchenHUGlosterATBeesdo-BaumKFavaGACraskeMGAgoraphobia: a review of the diagnostic classificatory position and criteriaDepress Anxiety201027211313320143426
  • PerugiGFrareFToniCDiagnosis and treatment of agoraphobia with panic disorderCNS Drugs200721974176417696574
  • SugayaNKaiyaHKumanoHNomuraSRelationship between sub-types of irritable bowel syndrome and severity of symptoms associated with panic disorderScand J Gastroenterol200843667568118569984
  • MichaelTBlechertJVriendsNMargrafJWilhelmFHFear conditioning in panic disorder: enhanced resistance to extinctionJ Abnorm Psychol2007116361261717696717
  • LissekSRabinSHellerREOvergeneralization of conditioned fear as a pathogenic marker of panic disorderAm J Psychiatry20101671475519917595
  • LissekSRabinSJMcDowellDJImpaired discriminative fear-conditioning resulting from elevated fear responding to learned safety cues among individuals with panic disorderBehav Res Ther200947211111819027893
  • BrittonJCLissekSGrillonCNorcrossMAPineDSDevelopment of anxiety: the role of threat appraisal and fear learningDepress Anxiety201128151720734364
  • McTeagueLMLangPJLaplanteMCBradleyMMAversive imagery in panic disorder: agoraphobia severity, comorbidity, and defensive physiologyBiol Psychiatry201170541542421550590
  • ZanoveliJMFerreira-NettoCBrandãoMLConditioned place aversion organized in the dorsal periaqueductal gray recruits the laterodorsal nucleus of the thalamus and the basolateral amygdalaExp Neurol2007208112713617900567
  • WittmannASchlagenhaufFJohnTA new paradigm (Westphal-Paradigm) to study the neural correlates of panic disorder with agoraphobiaEur Arch Psychiatry Clin Neurosci2011261318519421113608
  • CritchleyHDThe human cortex responds to an interoceptive challengeProc Natl Acad Sci U S A2004101176333633415096592
  • JohnstoneTvan ReekumCMUrryHLKalinNHDavidsonRJFailure to regulate: counterproductive recruitment of top-down prefrontal-subcortical circuitry in major depressionJ Neurosci200727338877888417699669
  • PasquiniMBerardelliIAnxiety levels and related pharmacological drug treatment: a memorandum for the third millenniumAnn Ist Super Sanita200945219320419636172
  • GormanJMKentJMSullivanGMCoplanJDNeuroanatomical hypothesis of panic disorder, revisedAm J Psychiatry2000157449350510739407
  • MyersKMDavisMMechanisms of fear extinctionMol Psychiatry200712212015017160066
  • VervlietBLearning and memory in conditioned fear extinction: effects of D-cycloserineActa Psychol (Amst)2008127360161317707326
  • LuftTPereiraGSCammarotaMIzquierdoIDifferent time course for the memory facilitating effect of bicuculline in hippocampus, entorhinal cortex, and posterior parietal cortex of ratsNeurobiol Learn Mem2004821525615183170
  • PernaGDarioACaldirolaDStefaniaBCesaraniABellodiLPanic disorder: the role of the balance systemJ Psychiatr Res200135527928611591430
  • StaabJPChronic dizziness: the interface between psychiatry and neuro-otologyCurr Opin Neurol2006191414816415676
  • RedfernMSFurmanJMJacobRGVisually induced postural sway in anxiety disordersJ Anxiety Disord200721570471617045776
  • CaldirolaDTeggiRBondiSIs there a hypersensitive visual alarm system in panic disorder?Psychiatry Res2011187338739121477868
  • BrandtTPhobic postural vertigoNeurology1996466151515198649539
  • LöscherWAbnormal circling behavior in rat mutants and its relevance to model specific brain dysfunctionsNeurosci Biobehav Rev2010341314919607857
  • LourencoSFLongoMRPathmanTNear space and its relation to claustrophobic fearCognition2011119344845321396630
  • KellnerMWiedemannKZihlJIllumination perception in photophobic patients suffering from panic disorder with agoraphobiaActa Psychiatr Scand199796172749259228
  • CastrogiovanniPPieracciniFIapichinoSElectroretinogram B-wave amplitude in panic disorderCNS Spectr20016321021316951655
  • PurdyRAThe role of the visual system in migraine: an updateNeurol Sci201132Suppl 1S89S9321533721
  • YamadaKMoriwakiKOisoHIshigookaJHigh prevalence of comorbidity of migraine in outpatients with panic disorder and effectiveness of psychopharmacotherapy for both disorders: a retrospective open label studyPsychiatry Res20111851–214514820546930
  • TeggiRCaldirolaDColomboBDizziness, migrainous vertigo and psychiatric disordersJ Laryngol Otol2010124328529019954562
  • Van ApeldoornFJTimmermanMEMerschPPA randomized trial of cognitive-behavioral therapy or selective serotonin reuptake inhibitor or both combined for panic disorder with or without agoraphobia: treatment results through 1-year follow-upJ Clin Psychiatry201071557458620492852
  • National Institute for Health and Clinical Excellence (NICE)Generalised anxiety disorder and panic disorder (with or without agoraphobia) in adults: management in primary, secondary and community careNICE clinical guideline11312011 Available at: http://www.nice.org.uk/nicemedia/live/13314/52599/52599.pdfAccessed on September 15, 2011
  • Van ApeldoornFJvan HoutWJMerschPPIs a combined therapy more effective than either CBT or SSRI alone? Results of a multicenter trial on panic disorder with or without agoraphobiaActa Psychiatr Scand2008117426027018307586
  • ToniCPerugiGFrareFMataBAkiskalHSSpontaneous treatment discontinuation in panic disorder patients treated with antidepressantsActa Psychiatr Scand2004110213013715233713
  • MavissakalianMRPerelJM2nd year maintenance and discontinuation of imipramine in panic disorder with agoraphobiaAnn Clin Psychiatry2001132636711534926
  • MavissakalianMRPerelJMDuration of imipramine therapy and relapse in panic disorder with agoraphobiaJ Clin Psychopharmacol200222329429912006900
  • MarchandACoutuMFDupuisGTreatment of panic disorder with agoraphobia: randomized placebo-controlled trial of four psychosocial treatments combined with imipramine or placeboCogn Behav Ther200837314615918608313
  • BandelowBBroocksAPekrunGThe use of the Panic and Agoraphobia Scale (P&A) in a controlled clinical trialPharmacopsychiatry200033517418111071019
  • PernaGBertaniACaldirolaDGabrieleACocchiSBellodiLAntipanic drug modulation of 35% CO2 hyperreactivity and short-term treatment outcomeJ Clin Psychopharmacol200222330030812006901
  • UhlenhuthEHWarnerTDMatuzasWInteractive model of therapeutic response in panic disorder: moclobemide, a case in pointJ Clin Psychopharmacol200222327528412006898
  • ValençaAMNardiAENascimentoIMezzasalmaMALopesFLZinWDouble-blind clonazepam vs placebo in panic disorder treatmentArq Neuropsiquiatr20005841025102911105068
  • ValençaAMNardiAEMezzasalmaMATherapeutic response to benzodiazepine in panic disorder subtypesSao Paulo Med J20031212778012870055
  • KatzelnickDJSaidiJVanelliMRJeffersonJWHarperJMMcCraryKETime to response in panic disorder in a naturalistic setting: combination therapy with alprazolam orally disintegrating tablets and serotonin reuptake inhibitors compared to serotonin reuptake inhibitors alonePsychiatry (Edgmont)2006312394920877555
  • UhlenhuthEHMatuzasWWarnerTDPaineSLydiardRBPollackMHDo antidepressants selectively suppress spontaneous (unexpected) panic attacks? A replicationJ Clin Psychopharmacol200020662262711106133
  • KampmanMKeijsersGPHoogduinCAHendriksGJA randomized, double-blind, placebo-controlled study of the effects of adjunctive paroxetine in panic disorder patients unsuccessfully treated with cognitive-behavioral therapy aloneJ Clin Psychiatry200263977277712363116
  • HendriksGJKeijsersGPKampmanMA randomized controlled study of paroxetine and cognitive-behavioural therapy for late-life panic disorderActa Psychiatr Scand20101221111919958308
  • WedekindDBroocksAWeissNEngelKNeubertKBandelowBA randomized, controlled trial of aerobic exercise in combination with paroxetine in the treatment of panic disorderWorld J Biol Psychiatry201011790491320602575
  • BandelowBBehnkeKLenoirSSertraline versus paroxetine in the treatment of panic disorder: an acute, double-blind noninferiority comparisonJ Clin Psychiatry200465340541315096081
  • StahlSMGergelILiDEscitalopram in the treatment of panic disorder: a randomized, double-blind, placebo-controlled trialJ Clin Psychiatry200364111322132714658946
  • BandelowBSteinDJDolbergOTAndersenHFBaldwinDSImprovement of quality of life in panic disorder with escitalopram, citalopram, or placeboPharmacopsychiatry200740415215617694478
  • PernaGBertaniACaldirolaDSmeraldiEBellodiLA comparison of citalopram and paroxetine in the treatment of panic disorder: a randomized, single-blind studyPharmacopsychiatry2001343859011434404
  • VersianiMCassanoGPerugiGReboxetine, a selective norepi-nephrine reuptake inhibitor, is an effective and well-tolerated treatment for panic disorderJ Clin Psychiatry2002631313711838623
  • BertaniAPernaGMigliareseGComparison of the treatment with paroxetine and reboxetine in panic disorder: a randomized, single-blind studyPharmacopsychiatry200437520621015359375
  • PollackMHLepolaUKoponenHA double-blind study of the efficacy of venlafaxine extended-release, paroxetine, and placebo in the treatment of panic disorderDepress Anxiety200724111416894619
  • PandeACPollackMHCrockattJPlacebo-controlled study of gabapentin treatment of panic disorderJ Clin Psychopharmacol200020446747110917408
  • SandfordJJForshallSBellCCrossover trial of pagoclone and placebo in patients with DSM-IV panic disorderJ Psychopharmacol200115320520811565630
  • OttoMWTolinDFSimonNMEfficacy of D-cycloserine for enhancing response to cognitive-behavior therapy for panic disorderBiol Psychiatry201067436537019811776
  • SiegmundAGolfelsFFinckCD-cycloserine does not improve but might slightly speed up the outcome of in-vivo exposure therapy in patients with severe agoraphobia and panic disorder in a randomized double blind clinical trialJ Psychiatr Res20114581042104721377691
  • PalatnikAFrolovKFuxMBenjaminJDouble-blind, controlled, crossover trial of inositol versus fluvoxamine for the treatment of panic disorderJ Clin Psychopharmacol200121333533911386498
  • MitteKA meta-analysis of the efficacy of psycho- and pharmacotherapy in panic disorder with and without agoraphobiaJ Affect Disord2005881274516005982
  • OttoMWBruceSEDeckersbachTBenzodiazepine use, cognitive impairment, and cognitive-behavioral therapy for anxiety disorders: issues in the treatment of a patient in needJ Clin Psychiatry200566Suppl 2343815762818
  • LevineJControlled trials of inositol in psychiatryEur Neuropsychopharmacol1997721471559169302
  • BenjaminJLevineJFuxMAvivALevyDBelmakerRHDouble- blind, placebo-controlled, crossover trial of inositol treatment for panic disorderAm J Psychiatry19951527108410867793450
  • PernaGAlpiniDCaldirolaDRaponiGCesaraniABellodiLSerotonergic modulation of the balance system in panic disorder: an open studyDepress Anxiety200317210110612621600
  • KaplanGBMooreKAThe use of cognitive enhancers in animal models of fear extinctionPharmacol Biochem Behav201199221722821256147
  • ResslerKJRothbaumBOTannenbaumLCognitive enhancers as adjuncts to psychotherapy: use of D-cycloserine in phobic individuals to facilitate extinction of fearArch Gen Psychiatry200461111136114415520361
  • MoreiraFALutzBThe endocannabinoid system: emotion, learning and addictionAddict Biol200813219621218422832
  • HernandezGCheerJFExtinction learning of rewards in the rat: is there a role for CB1 receptors?Psychopharmacology (Berl)2011217218919721519986
  • ChhatwalJPDavisMMaguschakKAResslerKJEnhancing cannabinoid neurotransmission augments the extinction of conditioned fearNeuropsychopharmacology200530351652415637635
  • OttoMWMcHughRKKantakKMCombined pharmacotherapy and cognitive-behavioral therapy for anxiety disorders: medication effects, glucocorticoids, and attenuated outcomesClin Psychol Sci Prac201017291103
  • de QuervainDJBentzDMichaelTGlucocorticoids enhance extinction-based psychotherapyProc Natl Acad Sci U S A2011108166621662521444799
  • SiegmundAKösterLMevesAMPlagJStoyMStröhleAStress hormones during flooding therapy and their relationship to therapy outcome in patients with panic disorder and agoraphobiaJ Psychiatr Res201145333934620673917