95
Views
7
CrossRef citations to date
0
Altmetric
Original Research

HDAC4 gene silencing alleviates epilepsy by inhibition of GABA in a rat model

, , , , , , & show all
Pages 405-416 | Published online: 04 Feb 2019

References

  • DuncanJSSanderJWSisodiyaSMWalkerMCAdult epilepsyLancet200636795161087110016581409
  • VezzaniAFrenchJBartfaiTBaramTZThe role of inflammation in epilepsyNat Rev Neurol201171314021135885
  • ZhangYSeeburgDPPulliBMyeloperoxidase nuclear imaging for epileptogenesisRadiology2016278382283026397127
  • VezzaniAFujinamiRSWhiteHSInfections, inflammation and epilepsyActa Neuropathol2016131221123426423537
  • NewtonCRGarciaHHEpilepsy in poor regions of the worldLancet201238098481193120123021288
  • GuLLiangBChenQPrevalence of epilepsy in the People’s Republic of China: a systematic reviewEpilepsy Res20131051–219520523507331
  • GuerriniRMariniCMantegazzaMGenetic epilepsy syndromes without structural brain abnormalities: clinical features and experimental modelsNeurotherapeutics201411226928524664660
  • LiZAnSCLiJNThe interaction between gamma-aminobutyric acid and other related neurotransmitters in depressionSheng Li Ke Xue Jin Zhan2014453190194 Chinese25219270
  • McKernanRMWhitingPJWhich GABAA-receptor subtypes really occur in the brain?Trends Neurosci19961941391438658597
  • WanLLiuXWuZActivation of extrasynaptic GABA(A) receptors inhibits cyclothiazide-induced epileptiform activity in hippocampal CA1 neuronsNeurosci Bull201430586687625260800
  • KragholmBKvistTMadsenKKDiscovery of a subtype selective inhibitor of the human betaine/GABA transporter 1 (BGT-1) with a non-competitive pharmacological profileBiochem Pharmacol201386452152823792119
  • LehreACRowleyNMZhouYDeletion of the betaine-GABA transporter (BGT1; slc6a12) gene does not affect seizure thresholds of adult miceEpilepsy Res2011951–2708121459558
  • YanuarAAzminahEYAndikaEYErlinaLSyahdiRRIn silico approach to finding new active compounds from histone deacetylase (HDAC) familyCurr Pharm Des201622233488349727075581
  • TrybaMDeath on the table during implantation of a hip prosthesis – a neglected peroperative risk?Reg Anaesth19891261071092587814
  • JungKHNohJHKimJKHDAC2 overexpression confers oncogenic potential to human lung cancer cells by deregulating expression of apoptosis and cell cycle proteinsJ Cell Biochem201211362167217722492270
  • SandoR3rdGounkoNPierautSLiaoLYatesJ3rdMaximovAHDAC4 governs a transcriptional program essential for synaptic plasticity and memoryCell2012151482183423141539
  • ParkDParkHKimYKimHJeoungDHDAC3 acts as a negative regulator of angiogenesisBMB Rep201447422723224286308
  • CohenTJChoiMCKapurMLiraVAYanZYaoTPHDAC4 regulates muscle fiber type-specific gene expression programsMol Cells201538434334825728750
  • FitzsimonsHLThe Class IIa histone deacetylase HDAC4 and neuronal function: Nuclear nuisance and cytoplasmic stalwart?Neurobiol Learn Mem201512314915826074448
  • ZengLSYangXZWenYFOverexpressed HDAC4 is associated with poor survival and promotes tumor progression in esophageal carcinomaAging (Albany NY)2016861236124827295551
  • LiZRanaTMMolecular mechanisms of RNA-triggered gene silencing machineriesAcc Chem Res20124571122113122304792
  • SunJLiXFengPRNAi-mediated silencing of fungal acuD gene attenuates the virulence of Penicillium marneffeiMed Mycol201452216717824577002
  • LundIVHuYRussekSJBrooks-KayalARGABA | mechanisms of GABA A receptor gene regulation in epilepsySchwartzkroinPEncyclopedia of Basic Epilepsy Research1st edCambridge, MAAcademic Press2009294298
  • LéviSLe RouxNEugèneEPoncerJCBenzodiazepine ligands rapidly influence GABAA receptor diffusion and clustering at hippocampal inhibitory synapsesNeuropharmacology20158819920824930360
  • MaoXMaPCaoDAltered expression of GABAA receptors (α4, γ2 subunit), potassium chloride cotransporter 2 and astrogliosis in tremor rat hippocampusBrain Res Bull2011865–637337921924329
  • ChenWShengPHuangZMicroRNA-381 regulates chondrocyte hypertrophy by inhibiting histone deacetylase 4 expressionInt J Mol Sci20161791377
  • ZhouZWangRYangXThe cAMP-responsive element binding protein (CREB) transcription factor regulates furin expression during human trophoblast syncytializationPlacenta2014351190791825175744
  • ZhaoZFanLFortressAMBoulwareMIFrickKMHippocampal histone acetylation regulates object recognition and the estradiol-induced enhancement of object recognitionJ Neurosci20123272344235122396409
  • ChoiMCCohenTJBarrientosTA direct HDAC4-MAP kinase crosstalk activates muscle atrophy programMol Cell201247112213222658415
  • BacksJWorstBCLehmannLHSelective repression of MEF2 activity by PKA-dependent proteolysis of HDAC4J Cell Biol2011195340341522042619
  • SchwartzSTruglioMScottMJFitzsimonsHLLong-term memory in drosophila is influenced by histone deacetylase HDAC4 interacting with SUMO-conjugating enzyme Ubc9Genetics201620331249126427182943
  • PayneHLDonoghuePSConnellyWMAberrant GABA(A) receptor expression in the dentate gyrus of the epileptic mutant mouse stargazerJ Neurosci200626338600860816914686
  • MaoXGuoFYuJUp-regulation of GABA transporters and GABA(A) receptor α1 subunit in tremor rat hippocampusNeurosci Lett2010486315015520851161
  • LiimatainenSPeltolaJEpilepsy associated with glutamic acid decarboxylase antibody (GADA)Eur J Neurol201219679922248348
  • StaggCJLangBBestJGAutoantibodies to glutamic acid decarboxylase in patients with epilepsy are associated with low cortical GABA levelsEpilepsia20105191898190120550553
  • MalarkeyEBParpuraVMechanisms of glutamate release from astrocytesNeurochem Int2008521–214215417669556
  • PirttimakiTParriHRCrunelliVAstrocytic GABA transporter GAT-1 dysfunction in experimental absence seizuresJ Physiol2013591482383323090943
  • MattiskeTLeeKGeczJFriocourtGShoubridgeCEmbryonic forebrain transcriptome of mice with polyalanine expansion mutations in the ARX homeobox geneHum Mol Genet201625245433544327798109
  • RajanISavelievaKVYeGLLoss of the putative catalytic domain of HDAC4 leads to reduced thermal nociception and seizures while allowing normal bone developmentPLoS One200948e661219672313