Effect of pre- and post-treatment with Bacopa monnieri (Brahmi) on phencyclidine-induced disruptions in object recognition memory and cerebral calbindin, parvalbumin, and calretinin immunoreactivity in rats

References

• Braff DL, Heaton R, Kuck J, et al. The generalized pattern of neuropsychological deficits in outpatients with chronic schizophrenia with heterogeneous Wisconsin Card Sorting Test results. Arch Gen Psychiatry. 1991;48(10):891–898. doi:10.1001/archpsyc.1991.018103400230031929758
   PubMed Web of Science ®Google Scholar
• Steinpreis RE. The behavioral and neurochemical effects of phencyclidine in humans and animals: some implications for modeling psychosis. Behav Brain Res. 1996;74:45–55. doi:10.1016/0166-4328(95)00162-X8851914
   PubMed Web of Science ®Google Scholar
• Bobes J, Garcia-Portilla MP, Bascaran MT, Saiz PA, Bousoño M. Quality of life in schizophrenic patients. Dialogues Clin Neurosci. 2007;9(2):215–226.17726919
   PubMedGoogle Scholar
• Leucht S, Cipriani A, Spineli L, et al. Comparative efficacy and tolerability of 15 antipsychotic drugs in schizophrenia: a multiple-treatments meta-analysis. Lancet. 2013;382:951–962. doi:10.1016/S0140-6736(13)60733-323810019
   PubMed Web of Science ®Google Scholar
• Heinrichs RW, Zakzanis KK. Neurocognitive deficit in schizophrenia: a quantitative review of the evidence. Neuropsychology. 1998;12(3):426–445. doi:10.1037/0894-4105.12.3.4269673998
   PubMed Web of Science ®Google Scholar
• Abdul-Monim Z, Reynolds GP, Neill JC. The effect of atypical and classical antipsychotics on sub-chronic PCP-induced cognitive deficits in a reversal-learning paradigm. Behav Brain Res. 2006;169(2):263–273. doi:10.1016/j.bbr.2006.01.00616500717
   PubMed Web of Science ®Google Scholar
• Grayson B, Idris NF, Neill JC. Atypical antipsychotics attenuate a sub-chronic PCP-induced cognitive deficit in the novel object recognition task in the rat. Behav Brain Res. 2007;184(1):31–38. doi:10.1016/j.bbr.2007.06.01217675172
   PubMed Web of Science ®Google Scholar
• McLean SL, Beck JP, Woolley ML, Neill JC. A preliminary investigation into the effects of antipsychotics on sub-chronic phencyclidine-induced deficits in attentional set-shifting in female rats. Behav Brain Res. 2008;189(1):152–158. doi:10.1016/j.bbr.2007.12.02918282619
   PubMed Web of Science ®Google Scholar
• McKibben CE, Jenkins TA, Adams HN, Harte MK, Reynolds GP. Effect of pretreatment with risperidone on phencyclidine-induced disruptions in object recognition memory and prefrontal cortex parvalbumin immunoreactivity in the rat. Behav Brain Res. 2010;208(1):132–136. doi:10.1016/j.bbr.2009.11.01819914297
   PubMed Web of Science ®Google Scholar
• Walters Y, Agius M. Do atypical antipsychotics improve cognition? Psychiatr Danub. 2014;26(Suppl 1):285–288.
   Google Scholar
• Shinomol GK, M.S. Bharath M. Exploring the role of “Brahmi” (Bacopa monnieri and Centella asiatica) in brain function and therapy. Recent Pat Endocr Metab Immune Drug Discov. 2011;5:33–49. doi:10.2174/18722141179435183322074576
   PubMedGoogle Scholar
• Rastogi M, Ojha RP, Prabu PC, Devi BP, Agrawal A, Dubey GP. Prevention of age-associated neurodegeneration and promotion of healthy brain ageing in female Wistar rats by long term use of bacosides. Biogerontology. 2012;13:183–195. doi:10.1007/s10522-011-9367-y22143822
   PubMed Web of Science ®Google Scholar
• Holcomb LA, Dhanasekaran M, Hitt AR, Young KA, Riggs M, Manyam BV. Bacopa monniera extract reduces amyloid levels in PSAPP mice. J Alzheimers Dis. 2006;9(3):243–251. doi:10.3233/JAD-2006-9303
   PubMed Web of Science ®Google Scholar
• Dhanasekaran M, Tharakan B, Holcomb LA, Hitt AR, Young KA, Manyam BV. Neuroprotective mechanisms of ayurvedic antidementia botanical Bacopa monniera. Phytother Res. 2007;21:965–969. doi:10.1002/(ISSN)1099-157317604373
   PubMed Web of Science ®Google Scholar
• Sarkar S, Mishra BR, Praharaj SK, Nizamie SH. Add-on effect of Brahmi in the management of schizophrenia. J Ayurveda Integr Med. 2012;3(4):223–225. doi:10.4103/0975-9476.10444823326095
   PubMedGoogle Scholar
• Piyabhan P, Wetchateng T. Cognitive enhancement effects of Bacopa monnieri (Brahmi) on novel object recognition and VGLUT1 density in the prefrontal cortex, striatum, and hippocampus of sub-chronic phencyclidine rat model of schizophrenia. J Med Assoc Thai. 2013;96(5):625–632.23745319
   PubMedGoogle Scholar
• Piyabhan P, Wetchateng T. Bacopa monnieri (Brahmi) enhanced cognitive function and prevented cognitive impairment by increasing VGLUT2 immunodensity in prefrontal cortex of sub-chronic phencyclidine rat model of schizophrenia. J Med Assoc Thai. 2015;98(Suppl 3):S7–15.26387382
   PubMedGoogle Scholar
• Piyabhan P, Wannasiri S, Naowaboot J. Bacopa monnieri (Brahmi) improved novel object recognition task and increased cerebral vesicular glutamate transporter type 3 in sub-chronic phencyclidine rat model of schizophrenia. Clin Exp Pharmacol Physiol. 2016;43(12):1234–1242. doi:10.1111/cep.2016.43.issue-1227562725
   PubMed Web of Science ®Google Scholar
• Kim JS, Kornhuber HH, Schmid-Burgk W, Holzmuller B. Low cerebrospinal fluid glutamate in schizophrenic patients and a new hypothesis on schizophrenia. Neurosci Lett. 1980;20:379–382. doi:10.1016/0304-3940(80)90178-06108541
   PubMed Web of Science ®Google Scholar
• Benes FM, McSparren J, Bird ED, SanGiovanni JP, Vincent SL. Deficits in small interneurons in prefrontal and cingulate cortices of schizophrenic and schizoaffective patients. Arch Gen Psychiatry. 1991;48:996–1001. doi:10.1001/archpsyc.1991.018103500360051747023
   PubMed Web of Science ®Google Scholar
• Akbarian S, Kim JJ, Potkin SG, et al. Gene expression for glutamic acid decarboxylase is reduced without loss of neurons in prefrontal cortex of schizophrenics. Arch Gen Psychiatry. 1995;52:258–266. doi:10.1001/archpsyc.1995.039501600080027702443
   PubMed Web of Science ®Google Scholar
• Toru M, Watanabe S, Shibuya H, et al. Neurotransmitters, receptors and neuropeptides in post-mortem brains of chronic schizophrenic patients. Acta Psychiatr Scand. 1988;78(2):121–137. doi:10.1111/j.1600-0447.1988.tb06312.x2906213
   PubMed Web of Science ®Google Scholar
• Volk DW, Austin MC, Pierri JN, Sampson AR, Lewis DA. Decreased glutamic acid decarboxylase67 messenger RNA expression in a subset of prefrontal cortical gamma-aminobutyric acid neurons in subjects with schizophrenia. Arch Gen Psychiatry. 2000;57:237–245. doi:10.1001/archpsyc.57.3.23710711910
   PubMed Web of Science ®Google Scholar
• Reynolds GP, Czudek C, Andrews HB. Deficit and hemispheric asymmetry of GABA uptake sites in the hippocampus in schizophrenia. Biol Psychiatry. 1990;27(9):1038–1044. doi:10.1016/0006-3223(90)90039-52159350
   PubMed Web of Science ®Google Scholar
• Simpson MD, Slater P, Deakin JF, Royston MC, Skan WJ. Reduced GABA uptake sites in the temporal lobe in schizophrenia. Neurosci Lett. 1989;107(1–3):211–215. doi:10.1016/0304-3940(89)90819-72616032
   PubMed Web of Science ®Google Scholar
• Sawaguchi T, Matsumura M, Kubota K. Delayed response deficits produced by local injection of bicuculline into the dorsolateral prefrontal cortex in Japanese Macaque Monkeys. Exp Brain Res. 1989;75:457–469. doi:10.1007/BF002498972744104
   PubMed Web of Science ®Google Scholar
• Volk DW, Lewis DA. GABA targets for the treatment of cognitive dysfunction in schizophrenia. Curr Neuropharmacol. 2005;3(1):45–62. doi:10.2174/157015905277339622545031
   PubMedGoogle Scholar
• Lipska BK, Weinberger DR. To model a psychiatric disorder in animals: schizophrenia as a reality test. Neuropsychopharmacology. 2000;23:223–239. doi:10.1016/S0893-133X(00)00137-810942847
   PubMed Web of Science ®Google Scholar
• Nicholi AM Jr. Phencyclidine hydrochloride (PCP) use among college students: subjective and clinical effects, toxicity, diagnosis, and treatment. J Am Coll Health. 1984;32:197–200. doi:10.1080/07448481.1984.103928066736429
   PubMedGoogle Scholar
• Smith DE. A clinical approach to the treatment of phencyclidine (PCP) abuse. Psychopharmacol Bull. 1980;16:67–70.
   Google Scholar
• Liden CB, Lovejoy FH Jr, Costello CE. Phencyclidine. Nine cases of poisoning. JAMA. 1975;234:513–516. doi:10.1001/jama.1975.032601800530241242171
   PubMed Web of Science ®Google Scholar
• Moghaddam B, Adams BW. Reversal of phencyclidine effects by a group II metabotropic glutamate receptor agonist in rats. Science. 1998;281:1349–1352. doi:10.1126/science.281.5381.13499721099
   PubMed Web of Science ®Google Scholar
• Hanania T, Hillman GR, Johnson KM. Augmentation of locomotor activity by chronic phencyclidine is associated with an increase in striatal NMDA receptor function and an upregulation of the NR1 receptor subunit. Synapse. 1999;31:229–239. doi:10.1002/(ISSN)1098-239610029241
   PubMed Web of Science ®Google Scholar
• Neill JC, Barnes S, Cook S, et al. Animal models of cognitive dysfunction and negative symptoms of schizophrenia: focus on NMDA receptor antagonism. Pharmacol Ther. 2010;128(3):419–432.20705091
   PubMed Web of Science ®Google Scholar
• Paxinos G, Watson C. The Rat Brain in Stereotaxic Coordinates. 4th ed. San Diego: Academic Press; 1998.
   Google Scholar
• Hashimoto K, Fujita Y, Iyo M. Phencyclidine-induced cognitive deficits in mice are improved by subsequent subchronic administration of fluvoxamine: role of sigma-1 receptors. Neuropsychopharmacology. 2007;32:514–521. doi:10.1038/sj.npp.130104716495935
   PubMed Web of Science ®Google Scholar
• Hashimoto K, Fujita Y, Shimizu M, Iyo M. Phencyclidine-induced cognitive deficits in mice are improved by subsequent subchronic administration of clozapine, but not haloperidol. Eur J Pharmacol. 2005;219:114–117. doi:10.1016/j.ejphar.2005.07.002
   Web of Science ®Google Scholar
• Hashimoto K, Ishima T, Fujita Y, et al. Phencyclidine-induced cognitive deficits in mice are improved by subsequent subchronic administration of the novel selective alpha7 nicotinic receptor agonist SSR180711. Biol Psychiatry. 2008;63:92–97. doi:10.1016/j.biopsych.2007.04.03417601496
   PubMed Web of Science ®Google Scholar
• Reynolds GP, Zhang ZJ, Beasley CL. Neurochemical correlates of cortical GABAergic deficits in schizophrenia: selective losses of calcium binding protein immunoreactivity. Brain Res Bull. 2001;55(5):579–584. doi:10.1016/S0361-9230(01)00526-311576754
   PubMed Web of Science ®Google Scholar
• Beasley CL, Reynolds GP. Parvalbumin-immunoreactive neurons are reduced in the prefrontal cortex of schizophrenics. Schizophr Res. 1997;24(3):349–355. doi:10.1016/S0920-9964(96)00122-39134596
   PubMed Web of Science ®Google Scholar
• Beasley CL, Zhang ZJ, Patten I, Reynolds GP. Selective deficits in prefrontal cortical GABAergic neurons in schizophrenia defined by the presence of calcium-binding proteins. Biol Psychiatry. 2002;52(7):708–715.12372661
   PubMed Web of Science ®Google Scholar
• Veerasakul S, Thanoi S, Reynolds GP, Nudmamud-Thanoi S. Effect of methamphetamine exposure on expression of calcium binding proteins in rat frontal cortex and hippocampus. Neurotox Res. 2016;30(3):427–433. doi:10.1007/s12640-016-9628-227179799
   PubMed Web of Science ®Google Scholar
• Zhang Z, Sun J, Reynolds GP. A selective reduction in the relative density of parvalbumin-immunoreactive neurons in the hippocampus in schizophrenia patients. Chin Med J (Engl). 2002;115(6):819–823.12123544
   PubMed Web of Science ®Google Scholar
• Harte MK, Powell SB, Swerdlow NR, Geyer MA, Reynolds GP. Deficits in parvalbumin and calbindin immunoreactive cells in the hippocampus of isolation reared rats. J Neural Transm. 2007;114(7):893–898. doi:10.1007/s00702-007-0627-617594127
   PubMed Web of Science ®Google Scholar
• Reynolds GP, Abdul-Monim Z, Neill JC, Zhang ZJ. Calcium binding protein markers of GABA deficits in schizophrenia–postmortem studies and animal models. Neurotox Res. 2004;6(1):57–61. doi:10.1007/BF0303329715184106
   PubMed Web of Science ®Google Scholar
• Katz RJ, Liebler L. GABA involvement in memory consolidation: evidence from posttrial amino-oxyacetic acid. Psychopharmacology. 1978;56:191–193. doi:10.1007/BF00431848417370
   PubMed Web of Science ®Google Scholar
• Michels L, Martin E, Klaver P, et al. Frontal GABA levels change during working memory. PLoS One. 2012;7:1–8. doi:10.1371/journal.pone.0031933
   Web of Science ®Google Scholar
• Fuster JM. The prefrontal cortex—an update: time is of the essence. Neuron. 2001;30:319–333. doi:10.1016/S0896-6273(01)00285-911394996
   PubMed Web of Science ®Google Scholar
• Davis HP, Squire LR. Protein synthesis and memory: a review. Psychol Bull. 1984;96:518–559. doi:10.1037/0033-2909.96.3.5186096908
   PubMed Web of Science ®Google Scholar
• Rossato JI, Bevilaqua LRM, Myskiw JC, Medina JH, Izquierdo I, Cammarota M. On the role of hippocampal protein synthesis in the consolidation and reconsolidation of object recognition memory. Learn Mem. 2007;14:36–46. doi:10.1101/lm.42260717272651
   PubMed Web of Science ®Google Scholar
• Balderas I, Chavez-Hurtado J, Rodriguez-Ortiz CJ, McGaugh JL, Salgado-Tonda P, Bermudez-Rattoni F. The consolidation of object and context recognition memory involve different regions of the temporal lobe. Learn Mem. 2008;15:618–624. doi:10.1101/lm.102800818723431
   PubMed Web of Science ®Google Scholar
• Tujioka K, Okuyama S, Yokogoshi H, et al. Dietary g-aminobutyric acid affects the brain protein synthesis rate in young rats. Amino Acids. 2007;32:255–560. doi:10.1007/s00726-006-0358-216755368
   PubMed Web of Science ®Google Scholar
• Gibney J, Wallace JD, Spinks T, et al. The effects of 10 years of recombinant human growth hormone (GH) in adult GH-deficient patients. J Clin Endocrinol Metab. 1999;84:2596–2602. doi:10.1210/jcem.84.8.591610443645
   PubMed Web of Science ®Google Scholar
• Deijen JB, de Boer H, van der Veen EA. Cognitive changes during growth hormone replacement in adult men. Psychoneuroendocrinology. 1998;23:45–55. doi:10.1016/S0306-4530(97)00092-99618751
   PubMed Web of Science ®Google Scholar
• Thanapreedawat P, Kobayashi H, Inui N, et al. GABA affects novel object recognition memory and working memory in rats. J Nutr Sci Vitaminol. 2013;59(2):152–157.23727647
   PubMed Web of Science ®Google Scholar
• Singh HK, Dhawan BN. Drugs affecting learning and memory. In: Tandon PN, Bijiani V, Wadhwa S, editors. Lectures in neurobiology, vol. 1. New Delhi: Wiley Eastern; 1992:189–207.
   Google Scholar
• Mathew J, Soman S, Sadanandan J, Paulose CS. Decreased GABA receptor in the striatum and spatial recognition memory deficit in epileptic rats: effect of Bacopa monnieri and bacoside-A. J Ethnopharmacol. 2010;130(2):255–261. doi:10.1016/j.jep.2010.04.02520451596
   PubMed Web of Science ®Google Scholar
• Singh HK, Dhawan BN. Neuropsycho-pharmacological effects of the Ayurvedic nootropic Bacopa monniera Linn. (Brahmi). Ind J Pharmcol. 1997;29:S359–365.
   Google Scholar
• Singh HK, Rastogi RP, Srimal RC, Dhawan BN. Effect of bacoside A and B on the avoidance responses in rats. Phytother Res. 1988;2:70–75. doi:10.1002/ptr.2650020205
   Google Scholar
• Reas SK, Amee K, Paulose CS. Glutamate receptor gene expression and binding studies in pilocarpine induced epileptic rat: neuroprotective role of Bacopa monnieri extract. Epilep Behav. 2008;12:54–60. doi:10.1016/j.yebeh.2007.09.021
   Web of Science ®Google Scholar
• Russo A, Izzo AA, Borrelli F, Renis M, Vanella A. Free radical scavenging capacity and protective effect of Bacopa monniera L. on DNA damage. Phytother Res. 2003;17:46–54. doi:10.1002/ptr.1061
   Web of Science ®Google Scholar
• Mathew J, Balakrishnan S, Antony S, Abraham PM, Paulose CS. Decreased GABA receptor in the cerebral cortex of epileptic rats: effect of Bacopa monnieri and Bacoside-A. J Biomed Sci. 2012;24:19–25.
   Google Scholar
• Mathew J, Gangadharan G, Kuruvilla KP, Paulose CS. Behavioral deficit and decreased GABA receptor functional regulation in the hippocampus of epileptic rats: effect of Bacopa monnieri. Monnieri Neurochem Res. 2011;36(1):7–16. doi:10.1007/s11064-010-0253-920821261
   PubMed Web of Science ®Google Scholar
• Mathew J, Peeyush Kumar T, Khan RS, Paulose CS. Behavioral deficit and decreased GABA receptor functional regulation in the cerebellum of epileptic rats: effect of Bacopa monnieri and bacoside A. Epilepsy Behav. 2010;17(4):441–447. doi:10.1016/j.yebeh.2009.12.01420153260
   PubMed Web of Science ®Google Scholar
• Moghaddam B, Adams B, Verma A, Daly D. Activation of glutamatergic neurotransmission by ketamine: a novel step in the pathway from NMDA receptor blockade to dopaminergic and cognitive disruptions associated with the prefrontal cortex. J Neurosci. 1997;17:2921–2927. doi:10.1523/JNEUROSCI.17-08-02921.19979092613
   PubMed Web of Science ®Google Scholar
• Yonezawa Y, Kuroki T, Kawahara T, Tashiro N, Uchimura H. Involvement of gamma-aminobutyric acid neurotransmission in phencyclidine-induced dopamine release in the medial prefrontal cortex. Eur J Pharmacol. 1998;341(1):45–56. doi:10.1016/S0014-2999(97)01435-09489855
   PubMed Web of Science ®Google Scholar
• Abdul-Monim Z, Neill JC, Reynolds GP. Sub-chronic psychotomimetic phencyclidine induces deficits in reversal learning and alterations in parvalbumin-immunoreactive expression in the rat. J Psychopharmacol. 2007;21:198–205. doi:10.1177/026988110706709717329300
   PubMed Web of Science ®Google Scholar
• Peth-Nui T, Wattanathorn J, Muchimapura S, et al. Effects of 12 week bacopa monnieri consumption on attention, cognitive processing, working memory, and functions of both cholinergic and monoaminergic systems in healthy elderly volunteers. Evid Based Complement Alternat Med. 2012;2012:606424. doi:10.1155/2012/60642423320031
   PubMed Web of Science ®Google Scholar
• Prabhakar S, Saraf MK, Pandhi P, Anand A. Bacopa monniera exerts antiamnesic effect on diazepam-induced anterograde amnesia in mice. Psychopharmacology (Berl). 2008;200(1):27–37. doi:10.1007/s00213-007-1049-818193203
   PubMed Web of Science ®Google Scholar
• Stough C, Lloyd J, Clarke J, et al. The chronic effects of an extract of Bacopa monniera (Brahmi) on cognitive function in healthy human subjects. Psychopharmacology (Berl). 2001;156:481–484. doi:10.1007/s00213010081511498727
   PubMed Web of Science ®Google Scholar
• Roodenrys S, Booth D, Bulzomi S, Phipps A, Micallef C, Smoker J. Chronic effects of Brahmi (Bacopa monnieri) on human memory. Neuropsychopharmacology. 2002;27:279–281. doi:10.1016/S0893-133X(02)00301-912093601
   PubMed Web of Science ®Google Scholar