GABA_B receptor activation ameliorates spatial memory impairments in stress-exposed rats

References

• Braastad BO. Effects of prenatal stress on behaviour of offspring of laboratory and farmed mammals. Appl Anim Behav Sci. 1998;61(2):159–180. doi:10.1016/S0168-1591(98)00188-9
   Web of Science ®Google Scholar
• Kofman O. The role of prenatal stress in the etiology of developmental behavioural disorders. Neurosci Biobehav Rev. 2002;26(4):457–470.
   PubMed Web of Science ®Google Scholar
• Peterson RA. Handbook of stress, medicine and health. J Health Psychol. 2000;5(2):255–256. doi:10.1177/135910530000500215
   Google Scholar
• Jacobs EH, Wardeh G, Smit AB, Schoffelmeer AN. Morphine causes a delayed increase in glutamate receptor functioning in the nucleus accumbens core. Eur J Pharmacol. 2005;511(1):27–30. doi:10.1016/j.ejphar.2005.02.009
   Web of Science ®Google Scholar
• Joels M, Baram TZ. The neuro-symphony of stress. Nat Rev Neurosci. 2009;10(6):459–466. doi:10.1038/nrn2632
   PubMed Web of Science ®Google Scholar
• Johnston GA. Neuropharmacology of amino acid inhibitory transmitters. Annu Rev Pharmacol Toxicol. 1978;18:269–289. doi:10.1146/annurev.pa.18.040178.001413
   PubMed Web of Science ®Google Scholar
• Sivilotti L, Nistri A. GABA receptor mechanisms in the central nervous system. Prog Neurobiol. 1991;36(1):35–92.
   PubMed Web of Science ®Google Scholar
• Bowery N, Enna SJ, Olsen RW. Six decades of GABA. Biochem Pharmacol. 2004;68(8):1477–1478. doi:10.1016/j.bcp.2004.07.033
   Web of Science ®Google Scholar
• Bettler B, Kaupmann K, Mosbacher J, Gassmann M. Molecular structure and physiological functions of GABA(B) receptors. Physiol Rev. 2004;84(3):835–867. doi:10.1152/physrev.00036.2003
   Web of Science ®Google Scholar
• Amikishieva AV, Semendyaeva SN. Effects of baclofen on anxiety, sexual motivation, and olfactory perception in male mice in different psychoemotional states. Neurosci Behav Physiol. 2007;37(9):929–937. doi:10.1007/s11055-007-0101-9
   Google Scholar
• Zarrindast M, Rostami P, Sadeghi-Hariri M. GABA(A) but not GABA(B) receptor stimulation induces antianxiety profile in rats. Pharmacol Biochem Behav. 2001;69(1–2):9–15.
   Web of Science ®Google Scholar
• Lopes AP, Ganzer L, Borges AC, et al. Effects of GABA ligands injected into the nucleus accumbens shell on fear/anxiety-like and feeding behaviours in food-deprived rats. Pharmacol Biochem Behav. 2012;101(1):41–48. doi:10.1016/j.pbb.2011.11.013
   Web of Science ®Google Scholar
• Li X, Risbrough VB, Cates-Gatto C, et al. Comparison of the effects of the GABAB receptor positive modulator BHF177 and the GABAB receptor agonist baclofen on anxiety-like behavior, learning, and memory in mice. Neuropharmacology. 2013;70:156–167. doi:10.1016/j.neuropharm.2013.01.018
   Web of Science ®Google Scholar
• Willner P, Muscat R, Papp M. Chronic mild stress-induced anhedonia: a realistic animal model of depression. Neurosci Biobehav Rev. 1992;16(4):525–534.
   PubMed Web of Science ®Google Scholar
• Barr AM, Markou A, Phillips AG. A ‘crash’ course on psychostimulant withdrawal as a model of depression. Trends Pharmacol Sci. 2002;23(10):475–482.
   PubMed Web of Science ®Google Scholar
• Brunoni AR, Lopes M, Fregni F. A systematic review and meta-analysis of clinical studies on major depression and BDNF levels: implications for the role of neuroplasticity in depression. Int J Neuropsychopharmacol. 2008;11(8):1169–1180. doi:10.1017/S1461145708009309
   PubMed Web of Science ®Google Scholar
• Strekalova T, Couch Y, Kholod N, et al. Update in the methodology of the chronic stress paradigm: internal control matters. Behav Brain Funct. 2011;7:9. doi:10.1186/1744-9081-7-9
   PubMed Web of Science ®Google Scholar
• Banasr M, Dwyer JM, Duman RS. Cell atrophy and loss in depression: reversal by antidepressant treatment. Curr Opin Cell Biol. 2011;23(6):730–737. doi:10.1016/j.ceb.2011.09.002
   PubMed Web of Science ®Google Scholar
• Sandi C, Haller J. Stress and the social brain: behavioural effects and neurobiological mechanisms. Nat Rev Neurosci. 2015;16(5):290–304. doi:10.1038/nrn3918
   PubMed Web of Science ®Google Scholar
• Park CR, Zoladz PR, Conrad CD, Fleshner M, Diamond DM. Acute predator stress impairs the consolidation and retrieval of hippocampus-dependent memory in male and female rats. Learn Mem. 2008;15(4):271–280. doi:10.1101/lm.721108
   Web of Science ®Google Scholar
• Annett LE, McGregor A, Robbins TW. The effects of ibotenic acid lesions of the nucleus accumbens on spatial learning and extinction in the rat. Behav Brain Res. 1989;31(3):231–242.
   Web of Science ®Google Scholar
• McGeorge AJ, Faull RL. The organization of the projection from the cerebral cortex to the striatum in the rat. Neuroscience. 1989;29(3):503–537.
   Web of Science ®Google Scholar
• Shirayama Y, Chaki S. Neurochemistry of the nucleus accumbens and its relevance to depression and antidepressant action in rodents. Curr Neuropharmacol. 2006;4(4):277–291.
   PubMed Web of Science ®Google Scholar
• Jacobson LH, Bettler B, Kaupmann K, Cryan JF. Behavioral evaluation of mice deficient in GABA(B(1)) receptor isoforms in tests of unconditioned anxiety. Psychopharmacology. 2007;190(4):541–553. doi:10.1007/s00213-006-0631-9
   Web of Science ®Google Scholar
• McNamara RK, Skelton RW. Baclofen, a selective GABAB receptor agonist, dose-dependently impairs spatial learning in rats. Pharmacol Biochem Behav. 1996;53(2):303–308.
   PubMed Web of Science ®Google Scholar
• Pitsikas N, Rigamonti AE, Cella SG, Muller EE. The GABAB receptor and recognition memory: possible modulation of its behavioral effects by the nitrergic system. Neuroscience. 2003;118(4):1121–1127.
   Web of Science ®Google Scholar
• Voigt RM, Herrold AA, Riddle JL, Napier TC. Administration of GABA(B) receptor positive allosteric modulators inhibit the expression of previously established methamphetamine-induced conditioned place preference. Behav Brain Res. 2011;216(1):419–423. doi:10.1016/j.bbr.2010.08.034
   PubMed Web of Science ®Google Scholar
• Heysieattalab S, Naghdi N, Zarrindast MR, Haghparast A, Mehr SE, Khoshbouei H. The effects of GABAA and NMDA receptors in the shell-accumbens on spatial memory of METH-treated rats. Pharmacol Biochem Behav. 2016;142:23–35. doi:10.1016/j.pbb.2015.12.008
   PubMed Web of Science ®Google Scholar
• Paxinos G, Franklin KB. The Mouse Brain in Stereotaxic Coordinates. Gulf professional publishing; Houston, TX, USA: 2004.
   Google Scholar
• Hooshmandi Z, Rohani AH, Eidi A, Fatahi Z, Golmanesh L, Sahraei H. Reduction of metabolic and behavioral signs of acute stress in male Wistar rats by saffron water extract and its constituent safranal. Pharm Biol. 2011;49(9):947–954. doi:10.3109/13880209.2011.558103
   PubMed Web of Science ®Google Scholar
• Rosenfeld CS, Ferguson SA. Barnes maze testing strategies with small and large rodent models. J Vis Exp. 2014;26(84):e51194.
   PubMed Web of Science ®Google Scholar
• Luo P, Chen C, Lu Y, et al. Baclofen ameliorates spatial working memory impairments induced by chronic cerebral hypoperfusion via up-regulation of HCN2 expression in the PFC in rats. Behav Brain Res. 2016;308:6–13. doi:10.1016/j.bbr.2016.04.020
   PubMed Web of Science ®Google Scholar
• Gill KM, Grace AA. Differential effects of acute and repeated stress on hippocampus and amygdala inputs to the nucleus accumbens shell. Int J Neuropsychopharmacol. 2013;16(9):2013–2025. doi:10.1017/S1461145713000618
   Web of Science ®Google Scholar
• Ebrahimi-Ghiri M, Rostampour M, Jamshidi-Mehr M, Nasehi M, Zarrindast MR. Role of CA1 GABAA and GABAB receptors on learning deficit induced by D-AP5 in passive avoidance step-through task. Brain Res. 2018;1678:164–173. doi:10.1016/j.brainres.2017.10.004
   Web of Science ®Google Scholar
• Swartzwelder HS, Tilson HA, McLamb RL, Wilson WA. Baclofen disrupts passive avoidance retention in rats. Psychopharmacology. 1987;92(3):398–401.
   Web of Science ®Google Scholar
• Castellano C, Brioni JD, Nagahara AH, McGaugh JL. Post-training systemic and intra-amygdala administration of the GABA-B agonist baclofen impairs retention. Behav Neural Biol. 1989;52(2):170–179.
   Google Scholar
• Holajova M, Franek M. Effect of short- and long-term administration of baclofen on spatial learning and memory in rats. Physiol Res. 2018;67(1):133–141. doi:10.33549/physiolres.933554
   Web of Science ®Google Scholar
• Pilipenko V, Narbute K, Beitnere U, et al. Very low doses of muscimol and baclofen ameliorate cognitive deficits and regulate protein expression in the brain of a rat model of streptozocin-induced Alzheimer’s disease. Eur J Pharmacol. 2018;818:381–399. doi:10.1016/j.ejphar.2017.11.012
   Web of Science ®Google Scholar
• Kim W, Seo H. Baclofen, a GABAB receptor agonist, enhances ubiquitin-proteasome system functioning and neuronal survival in Huntington’s disease model mice. Biochem Biophys Res Commun. 2014;443(2):706–711. doi:10.1016/j.bbrc.2013.12.034
   PubMed Web of Science ®Google Scholar
• Akaike N. Time-dependent rundown of GABA response in mammalian cns neuron during experimental anoxia. Obes Res. 1995;3 Suppl 5:769s–777s.
   Google Scholar
• Wang J-H, Lu W, Wen B. Neuron-specific mechanisms for epilepsy self-termination. Mol Cell Epilepsy. 2015;3, e716. doi:10.14800/mce.716
   Google Scholar
• Karolewicz B, Maciag D, O’Dwyer G, Stockmeier CA, Feyissa AM, Rajkowska G. Reduced level of glutamic acid decarboxylase-67 kDa in the prefrontal cortex in major depression. Int J Neuropsychopharmacol. 2010;13(4):411–420. doi:10.1017/S1461145709990587
   Web of Science ®Google Scholar
• Xu A, Cui S, Wang JH. Incoordination among subcellular compartments is associated with depression-like behavior induced by chronic mild stress. Int J Neuropsychopharmacol. 2016;19(5). doi:10.1093/ijnp/pyv122
   Web of Science ®Google Scholar
• Deng PY, Xiao Z, Yang C, et al. GABA(B) receptor activation inhibits neuronal excitability and spatial learning in the entorhinal cortex by activating TREK-2 K+ channels. Neuron. 2009;63(2):230–243. doi:10.1016/j.neuron.2009.06.022
   Web of Science ®Google Scholar
• Heaney CF, Bolton MM, Murtishaw AS, Sabbagh JJ, Magcalas CM, Kinney JW. Baclofen administration alters fear extinction and GABAergic protein levels. Neurobiol Learn Mem. 2012;98(3):261–271. doi:10.1016/j.nlm.2012.09.005
   Web of Science ®Google Scholar