Galuteolin attenuates cerebral ischemia/reperfusion injury in rats via anti-apoptotic, anti-oxidant, and anti-inflammatory mechanisms

References

• Sun J, Wang F, Ling Z, et al. Clostridium butyricum attenuates cerebral ischemia/reperfusion injury in diabetic mice via modulation of gut microbiota. Brain Res. 2016;1642:180–188. doi:10.1016/j.brainres.2016.03.04227037183
   PubMed Web of Science ®Google Scholar
• Ma Y, Lu C, Li C, et al. Overexpression of HSPA12B protects against cerebral ischemia/reperfusion injury via a PI3K/Akt-dependent mechanism. Biochim Biophys Acta. 2013;1832(1):57–66. doi:10.1016/j.bbadis.2012.10.00323046810
   PubMed Web of Science ®Google Scholar
• Zhang Y, Lin R, Tao J, et al. Electroacupuncture improves cognitive ability following cerebral ischemia reperfusion injury via CaM-CaMKIV-CREB signaling in the rat hippocampus. Exp Ther Med. 2016;12(2):777–782. doi:10.3892/etm.2016.342827446275
   PubMed Web of Science ®Google Scholar
• Gong J, Sun F, Li Y, et al. Momordica charantia polysaccharides could protect against cerebral ischemia/reperfusion injury through inhibiting oxidative stress mediated c-Jun N-terminal kinase 3 signaling pathway. Neuropharmacology. 2015;91:123–134. doi:10.1016/j.neuropharm.2014.11.02025510970
   PubMed Web of Science ®Google Scholar
• Zhao S, Yin J, Zhou L, et al. Hippo/MST1 signaling mediates microglial activation following acute cerebral ischemia-reperfusion injury. Brain Behav Immun. 2016;55:236–248. doi:10.1016/j.bbi.2015.12.01626721416
   PubMed Web of Science ®Google Scholar
• Yun Q, Jiang M, Wang J, et al. Overexpression Bax interacting factor-1 protects cortical neurons against cerebral ischemia-reperfusion injury through regulation of ERK1/2 pathway. J Neurol Sci. 2015;357(1):183–191. doi:10.1016/j.jns.2015.07.02726253702
   PubMed Web of Science ®Google Scholar
• Chen B, Wu Z, Xu J, Xu Y. Calreticulin binds to fas ligand and inhibits neuronal cell apoptosis induced by ischemia-reperfusion injury. Biomed Res Int. 2015;2015:895284. doi:10.1155/2015/89528426583143
   PubMed Web of Science ®Google Scholar
• Liao J, Ye Z, Huang G, Xu C, Guo Q, Wang E. Delayed treatment with NSC23766 in streptozotocin-induced diabetic rats ameliorates post-ischemic neuronal apoptosis through suppression of mitochondrial p53 translocation. Neuropharmacology. 2014;85:508–516. doi:10.1016/j.neuropharm.2014.06.00824953831
   PubMed Web of Science ®Google Scholar
• Ma L, Xing G, Yu Y, et al. Sulforaphane exerts neuroprotective effects via suppression of the inflammatory response in a rat model of focal cerebral ischemia. Int J Clin Exp Med. 2015;8(10):17811–17817.26770373
   PubMed Web of Science ®Google Scholar
• Jiang M, Li J, Peng Q, et al. Neuroprotective effects of bilobalide on cerebral ischemia and reperfusion injury are associated with inhibition of pro-inflammatory mediator production and down-regulation of JNK1/2 and p38 MAPK activation. J Neuroinflammation. 2014;11(1):167. doi:10.1186/s12974-014-0167-625256700
   PubMed Web of Science ®Google Scholar
• Han D, Zhang S, Fan B, et al. Ischemic postconditioning protects the neurovascular unit after focal cerebral ischemia/reperfusion injury. J Mol Neurosci. 2014;53(1):50–58. doi:10.1007/s12031-013-0196-024337985
   PubMed Web of Science ®Google Scholar
• Xin H, Feng J, Cheng R-M, Xin N. Simultaneous determination of chlorogenic acid and galuteolin in honeysuckle. Chin J Exp Tradit Med Formulae. 2011;2.
   Google Scholar
• Zhang X, Tong J, Zhou Y, Xiaoyu X. Studies on medicinal ingredients and pharmacological effects of Lonicera. Chin Pharmacol Bull. 2014;8:1049–1054.
   Google Scholar
• Wang G, Li W, Lu X, Bao P, Zhao X. Luteolin ameliorates cardiac failure in type I diabetic cardiomyopathy. J Diabetes Complications. 2012;26(4):259–265. doi:10.1016/j.jdiacomp.2012.04.00722626874
   PubMed Web of Science ®Google Scholar
• Lv L, Lv L, Zhang Y, Kong Q. Luteolin prevents LPS-induced TNF-α expression in cardiac myocytes through inhibiting NF-κB signaling pathway. Inflammation. 2011;34(6):620–629. doi:10.1007/s10753-010-9271-721076936
   PubMed Web of Science ®Google Scholar
• Fan S, Wang Y, Lu J, et al. Luteoloside suppresses proliferation and metastasis of hepatocellular carcinoma cells by inhibition of NLRP3 inflammasome. PLoS One. 2014;9(2):e89961.24587153
   PubMed Web of Science ®Google Scholar
• Wang X, Yuan T, Yin N, et al. Luteoloside protects the uterus from staphylococcus aureus-induced inflammation, apoptosis, and injury. Inflammation. 2018;41(5):1702–1716. doi:10.1007/s10753-018-0814-729987481
   PubMed Web of Science ®Google Scholar
• Liu Z, Yang L, Huang J, et al. Luteoloside attenuates anoxia/reoxygenation‐induced cardiomyocytes injury via mitochondrial pathway mediated by 14‐3‐3η protein. Phytotherapy Res. 2018;32(6):1126–1134. doi:10.1002/ptr.6053
   Web of Science ®Google Scholar
• Li X, Wu C, Chen N, et al. PI3K/Akt/mTOR signaling pathway and targeted therapy for glioblastoma. Oncotarget. 2016;7(22):33440.26967052
   PubMedGoogle Scholar
• Liu P, Zhao H, Wang R, et al. MicroRNA-424 protects against focal cerebral ischemia and reperfusion injury in mice by suppressing oxidative stress. Stroke. 2015;46(2):513–519. doi:10.1161/STROKEAHA.114.00748225523055
   PubMed Web of Science ®Google Scholar
• Ferrara N, Adamis AP. Ten years of anti-vascular endothelial growth factor therapy. Nat Rev Drug Discov. 2016;15(6):385.26775688
   PubMed Web of Science ®Google Scholar
• Bahr Hosseini M, Hou J, Bikson M, Iacoboni M, Saver JL. Abstract TP72: transcranial Direct Current Stimulation (tDCS) for neuroprotection in acute cerebral ischemia: meta-analysis of preclinical studies and implications for human clinical trials. Stroke. 2018;49(Suppl_1):ATP72–ATP72. doi:10.1161/str.49.suppl_1.TP72
   Google Scholar
• Enzmann G, Kargaran S, Engelhardt B. Ischemia–reperfusion injury in stroke: impact of the brain barriers and brain immune privilege on neutrophil function. Ther Adv Neurol Disord. 2018;11:1756286418794184. doi:10.1177/175628641879418430181779
   PubMed Web of Science ®Google Scholar
• Zhan J, Xiaoqiong L, Hao R. Effect of dendrobium nobile polysaccharides on focal cerebral ischemia/reperfusion rats. Chin J Cerebrovasc Dis. 2017;14(1):25–31.
   Google Scholar
• Huang J-L, Liu -W-W, Sun X-J. Hydrogen inhalation improves mouse neurological outcomes after cerebral ischemia/reperfusion independent of anti-necroptosis. Med Gas Res. 2018;8(1):1. doi:10.4103/2045-9912.22959629770189
   PubMed Web of Science ®Google Scholar
• Xie W, Zhou P, Sun Y, et al. Protective effects and target network analysis of ginsenoside Rg1 in cerebral ischemia and reperfusion injury: a comprehensive overview of experimental studies. Cells. 2018;7(12):270. doi:10.3390/cells7120270
   PubMed Web of Science ®Google Scholar
• Zheng Q, Wang B, Gao J, et al. CD 155 knockdown promotes apoptosis via AKT/Bcl‐2/Bax in colon cancer cells. J Cell Mol Med. 2018;22(1):131–140. doi:10.1111/jcmm.1330128816021
   PubMed Web of Science ®Google Scholar
• Rogers C, Erkes DA, Nardone A, Aplin AE, Fernandes-Alnemri T, Alnemri ES. Gasdermin pores permeabilize mitochondria to augment caspase-3 activation during apoptosis and inflammasome activation. Nat Commun. 2019;10(1):1689. doi:10.1038/s41467-019-09397-230976076
   PubMed Web of Science ®Google Scholar
• Sinha D, Kalimutho M, Bowles J, et al. Cep55 overexpression causes male-specific sterility in mice by suppressing Foxo1 nuclear retention through sustained activation of PI3K/Akt signaling. Faseb J. 2018;32(9):4984–4999. doi:10.1096/fj.201701096RR29683733
   PubMed Web of Science ®Google Scholar
• Sun D, Huang J, Zhang Z, et al. Luteolin limits infarct size and improves cardiac function after myocardium ischemia/reperfusion injury in diabetic rats. PLoS One. 2012;7(3):e33491. doi:10.1371/journal.pone.003349122432030
   PubMed Web of Science ®Google Scholar
• Bavarsad K, Barreto GE, Sahebkar A. Protective effects of curcumin against ischemia-reperfusion injury in the nervous system. Mol Neurobiol. 2019;56(2):1391–1404. doi:10.1007/s12035-018-1169-729948942
   PubMed Web of Science ®Google Scholar
• Conrad M, Kagan VE, Bayir H, et al. Regulation of lipid peroxidation and ferroptosis in diverse species. Genes Dev. 2018;32(9–10):602–619. doi:10.1101/gad.314674.11829802123
   PubMed Web of Science ®Google Scholar
• Ighodaro O, Akinloye O. First line defence antioxidants-superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPX): their fundamental role in the entire antioxidant defence grid. Alexandria J Med. 2018;54(4):287–293. doi:10.1016/j.ajme.2017.09.001
   Web of Science ®Google Scholar
• Shekhar S, Jain S, Priya P. Assessment of serum antioxidant enzymes superoxide dismutase (SOD) and glutathione peroxidase in oral submucous fibrosis. J Adv Med Dent Sci Res. 2019;7(1):1–5.
   Google Scholar
• Chen C, Li T, Zhao Y, et al. Platelet glycoprotein receptor Ib blockade ameliorates experimental cerebral ischemia–reperfusion injury by strengthening the blood–brain barrier function and anti-thrombo-inflammatory property. Brain Behav Immun. 2018;69:255–263. doi:10.1016/j.bbi.2017.11.01929195783
   PubMed Web of Science ®Google Scholar
• Sun JC, Wua ST, Lee KJ, Sun YM. Docking prediction for luteolin inhibiting TNF-α and NF-κB pathway. Lett Drug Des. 2012;9(2):169–176. doi:10.2174/157018012799079707
   Web of Science ®Google Scholar