Effect Of An Extra-Virgin Olive Oil Intake On The Delay Of Cognitive Decline: Role Of Secoiridoid Oleuropein?

References

• United Nations. Ageing. Available from: http://www.un.org/en/sections/issues-depth/ageing/ Accessed 18, 2019.
   Google Scholar
• Klimova B, Valis M, Kuca K. Cognitive decline in normal aging and its prevention: A review on non-pharmacological lifestyle strategies. Clin Interv Aging. 2017;12:903–910. doi:10.2147/CIA.S13296328579767
   PubMed Web of Science ®Google Scholar
• Alzheimer´s Association. 2014 Alzheimer’s disease facts and figures. Alzheimers Dement. 2014;10(2):e47–e92.24818261
   PubMed Web of Science ®Google Scholar
• Klimova B, Maresova P, Kuca K. Non-pharmacological approaches to the prevention and treatment of Alzheimer´s disease with respect to the rising treatment costs. Curr Alzheimer Res. 2016;13(11):1249–1258.26567732
   PubMed Web of Science ®Google Scholar
• Klimova B, Maresova P, Valis M, Hort J, Kuca K. Alzheimer´s disease and language impairments: social intervention and medical treatment. Clin Interv Aging. 2015;10:1401–1408. doi:10.2147/CIA.S8971426346123
   PubMed Web of Science ®Google Scholar
• Hardman RJ, Kennedy G, Macpherson H, Scholey AB, Pipingas A. A randomised controlled trial investigating the effects of mediterranean diet and aerobic exercise on cognition in cognitively healthy older people living independently within aged care facilities: the Lifestyle Intervention in Independent Living Aged Care (LIILAC) study protocol [ACTRN12614001133628]. Nutr J. 2015;14:53.26003546
   PubMed Web of Science ®Google Scholar
• Hardman RJ, Kennedy G, Macpherson H, Scholey AB, Pipingas A. Adherence to a Mediterranean-style diet and effects on cognition in adults: a qualitative evaluation and systematic review of longitudinal and prospective trials. Front Nutr. 2016;3:22. doi:10.3389/fnut.2016.0002227500135
   PubMedGoogle Scholar
• Klimova B. Computer-based cognitive training in aging. Front Aging Neurosci. 2016;8:313. doi:10.3389/fnagi.2016.0031328066236
   PubMed Web of Science ®Google Scholar
• Kivipelto M, Solomon A, Ahtiluoto S, et al. The Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER): study design and progress. Alzheimers Dement. 2013;9(6):657–665. doi:10.1016/j.jalz.2012.09.01223332672
   PubMed Web of Science ®Google Scholar
• Ngandu T, Lehtisalo J, Solomon A, et al. A 2 year multidomain intervention of diet, exercise, cognitive training, and vascular risk monitoring versus control to prevent cognitive decline in at-risk elderly people (FINGER): a randomised controlled trial. Lancet. 2015;385(9984):2255–2263. doi:10.1016/S0140-6736(15)60461-525771249
   PubMed Web of Science ®Google Scholar
• Visioli F, Franco M, Toledo E, et al. Olive oil and prevention of chronic diseases: summary of an international conference. Nutr Metab Cardiovasc Dis. 2018;28(7):649–656. doi:10.1016/j.numecd.2018.04.00429804831
   PubMed Web of Science ®Google Scholar
• Locke A, Schneiderhan J, Zick SM. Diets for health: goals and guidelines. Am Fam Physician. 2018;97(11):721–728.30215930
   PubMed Web of Science ®Google Scholar
• Mazza E, Fava A, Ferro Y, et al. Effect of the replacement of dietary vegetable oils with a low dose of extravirgin olive oil in the mediterranean diet on cognitive functions in the elderly. J Transl Med. 2018;16(1):10. doi:10.1186/s12967-018-1386-x29351799
   PubMed Web of Science ®Google Scholar
• López-Miranda J, Pérez-Jiménez F, Ros E, et al. Olive oil and health: summary of the II international conference on olive oil and health consensus report, Jaén and Córdoba (Spain) 2008. Nutr Metab Cardiovasc Dis. 2010;20(4):284–294. doi:10.1016/j.numecd.2009.12.00720303720
   PubMed Web of Science ®Google Scholar
• Delgado-Lista J, Garcia-Rios A, Perez-Martinez P, Lopez-Miranda J, Perez-Jimenez F. Olive oil and haemostasis: platelet function, thrombogenesis and fibrinolysis. Curr Pharm Des. 2011;17(8):778–785. doi:10.2174/13816121179542887621443486
   PubMed Web of Science ®Google Scholar
• Perez-Jimenez F, Alvarez de Cienfuegos G, Badimon L, et al. International conference on the healthy effect of virgin olive oil. Eur J Clin Invest. 2005;35(7):421–424. doi:10.1111/j.1365-2362.2005.01516.x16008542
   PubMed Web of Science ®Google Scholar
• Covas MI, de la Torre R, Fito M. Scientific evidence of the benefits of virgin olive oil for human health. Med Balear. 2014;29(2):39–46.
   Google Scholar
• Martinez-Gonzalez MA, Martin-Calvo N. Mediterranean diet and life expectancy; beyond olive oil, fruits, and vegetables. Curr Opin Clin Nutr Metab Care. 2016;19(6):401–407. doi:10.1097/MCO.000000000000031627552476
   PubMed Web of Science ®Google Scholar
• Vassiloudis I, Yiannakouris N, Panagiotakos DB, Apostolopoulos K, Costarelli V. Adherence to the mediterranean diet and specific lifestyle habits are associated with academic performance in Greek adolescents. MNM. 2017;10(2):93–103. doi:10.3233/MNM-16133
   Google Scholar
• Tehrani AN, Salehpour A, Beyzai B, et al. Adherence to Mediterranean dietary pattern and depression, anxiety and stress among high-school female adolescents. MNM. 2018;11(1):73–83. doi:10.3233/MNM-17192
   Web of Science ®Google Scholar
• Valls-Pedret C, Lamuela-Raventós RM, Medina-Remón A, et al. Polyphenol-rich foods in the mediterranean diet are associated with better cognitive function in elderly subjects at high cardiovascular risk. J Alzheimers Dis. 2012;29(4):773–782. doi:10.3233/JAD-2012-11179922349682
   PubMed Web of Science ®Google Scholar
• Quiles JL, Barja G, Battino M, Mataix J, Solfrizzi V. Role of olive oil and monounsaturated fatty acids in mitochondrial oxidative stress and aging. Nutr Rev. 2006;64(s4):31–39. doi:10.1111/j.1753-4887.2006.tb00170.x16491667
   PubMed Web of Science ®Google Scholar
• St-Laurent-Thibault C, Arseneault M, Longpré F, Ramassamy C. Tyrosol and hydroxytyrosol, two main components of olive oil, protect N2a cells against amyloid-β-induced toxicity. Involvement of the NF-κB signaling. Curr Alzheimer Res. 2011;8(5):543–551.21605049
   PubMed Web of Science ®Google Scholar
• Martorell M, Forman K, Castro N, Capó X, Tejada S, Sureda A. Potential therapeutic effects of oleuropein aglycone in Alzheimer’s disease. Curr Pharm Biotechnol. 2016;17:994–1001. doi:10.2174/138920101766616072512065627455905
   PubMed Web of Science ®Google Scholar
• Fleming HP, Walter WM, Etchells JL. Antimicrobial properties of oleuropein and products of its hydrolysis from green olives. Appl Microbiol. 1973;26:777–782.4762397
   PubMedGoogle Scholar
• Morley JE. An overview of cognitive impairment. Clin Geriatr Med. 2018;34(4):505–513. doi:10.1016/j.cger.2018.06.00330336985
   PubMed Web of Science ®Google Scholar
• Visioli F, Poli A, Gall C. Antioxidant and other biological activities of phenols from olives and olive oil. Med Res Rev. 2002;22:65–75.11746176
   PubMed Web of Science ®Google Scholar
• Soler-Rivas C, Espín JC, Wichers HJ. Oleuropein and related compounds. J Sci Food Agric. 2000;80:1013–1023. doi:10.1002/(SICI)1097-0010(20000515)80:7<1013::AID-JSFA571>3.0.CO;2-C
   Web of Science ®Google Scholar
• Amiot MJ, Fleuriet A, Macheix JJ. Accumulation of oleuropein derivatives during olive maturation. Phytochemistry. 1989;28:67–69. doi:10.1016/0031-9422(89)85009-5
   Web of Science ®Google Scholar
• Omar SH. Cardioprotective and neuroprotective roles of oleuropein in olive. Saudi Pharm J. 2010;18(3):111–121. doi:10.1016/j.jsps.2010.05.00523964170
   PubMedGoogle Scholar
• Rigacci S. Olive oil phenols as promising multi-targeting agents against Alzheimer’s disease. Adv Exp Med Biol. 2005;863:1–20.
   Google Scholar
• Barbaro B, Toietta G, Maggio R, et al. Effects of the olive-derived polyphenol oleuropein on human health. IJMS. 2014;15(10):18508–18524.25318054
   PubMed Web of Science ®Google Scholar
• Xu F, Li Y, Zheng M, Xi X, Zhang X, Han C. Structure properties, acquisition protocols, and biological activities of oleuropein aglycone. Front Chem. 2018;6:239. doi:10.3389/fchem.2018.0023930151359
   PubMed Web of Science ®Google Scholar
• Angeloni C, Malaguti M, Barbalace M, Hrelia S. Bioactivity of olive oil phenols in neuroprotection. IJMS. 2017;18(11):2230. doi:10.3390/ijms18112230
   Web of Science ®Google Scholar
• Cordero JG, García-Escudero R, Avila J, Gargini R, García-Escudero V. Benefit of oleuropein aglycone for Alzheimer’s disease by promoting autophagy. Oxid Med Cell Longev. 2018;2018:5010741. doi:10.1155/2018/501074129675133
   PubMed Web of Science ®Google Scholar
• Martínez-Lapiscina EH, Clavero P, Toledo E, et al. Virgin olive oil supplementation and long-term cognition: the PREDIMED-NAVARRA randomized, trial. J Nutr Health Aging. 2013;17(6):544–552. doi:10.1007/s12603-013-0027-623732551
   PubMed Web of Science ®Google Scholar
• Pitozzi V, Jacomelli M, Catelan D, et al. Long-term dietary extra-virgin olive oil rich in polyphenols reverses age-related dysfunctions in motor coordination and contextual memory in mice: role of oxidative stress. Rejuvenation Res. 2012;15:601–612. doi:10.1089/rej.2012.134622950431
   PubMed Web of Science ®Google Scholar
• Grossi C, Rigacci S, Ambrosini S, et al. The polyphenol oleuropein aglycone protects TgCRND8 mice against Aß plaque pathology. PLoS One. 2013;8:e71702. doi:10.1371/journal.pone.007170223951225
   PubMed Web of Science ®Google Scholar
• Grossi C, Dami TE, Rigacci S, Stefani M, Luccarini I, Casamenti F. Employing Alzheimer disease animal models for translational research: focus on dietary components. Neurodegener Dis. 2014;13:131–134. doi:10.1159/00035546124192327
   PubMed Web of Science ®Google Scholar
• Luccarini I, Dami TE, Grossi C, Rigacci S, Stefani M, Casamenti F. Oleuropein aglycone counteracts Aβ42 toxicity in the rat brain. Neurosci Lett. 2014;558:67–72. doi:10.1016/j.neulet.2013.10.06224211687
   PubMed Web of Science ®Google Scholar
• Diomede L, Rigacci S, Romeo M, Stefani M, Salmona M. Oleuropein aglycone protects transgenic C. elegans strains expressing Aβ42 by reducing plaque load and motor deficit. PLoS One. 2013;8:e58893. doi:10.1371/journal.pone.005889323520540
   PubMed Web of Science ®Google Scholar
• Lauretti E, Iuliano L, Praticò D. Extra-virgin olive oil ameliorates cognition and neuropathology of the 3xTg mice: role of autophagy. Ann Clin Transl Neurol. 2017;4(8):564–574. doi:10.1002/acn3.43128812046
   PubMed Web of Science ®Google Scholar
• Gorzynik-Debicka M, Przychodzen P, Cappello F, et al. Potential health benefits of olive oil and plant polyphenols. Int J Mol Sci. 2018;19(3):pii,E6. doi:10.3390/ijms19030686
   Web of Science ®Google Scholar
• Rigacci S. Olive oil phenols as promising multi-targeting agents against Alzheimer’s disease. Adv Exp Med Biol. 2015;863:1–20. doi:10.1007/978-3-319-18365-7_126092624
   PubMed Web of Science ®Google Scholar
• Visioli F, Galli C. Oleuropein protects low density lipoprotein from oxidation. Life Sci. 1994;55(24):1965–1971. doi:10.1016/0024-3205(94)00529-x7990657
   PubMed Web of Science ®Google Scholar
• Ogun M, Ozcan A, Karaman M, et al. Oleuropein ameliorates arsenic induced oxidative stress in mice. J Trace Elem Med Biol. 2016;36:1–6. doi:10.1016/j.jtemb.2016.03.00627259345
   PubMed Web of Science ®Google Scholar
• Peng S, Zhang B, Yao J, Duan D, Fang J. Dual protection of hydroxytyrosol, an olive oil polyphenol, against oxidative damage in PC12 cells. Food Funct. 2015;6(6):2091–2100. doi:10.1039/c5fo00097a26037629
   PubMed Web of Science ®Google Scholar
• Yu H, Liu P, Tang H, et al. Oleuropein, a natural extract from plants, offers neuroprotection in focal cerebral ischemia/reperfusion injury in mice. Eur J Pharmacol. 2016;775:113–119. doi:10.1016/j.ejphar.2016.02.02726872990
   PubMed Web of Science ®Google Scholar
• Impellizzeri D, Esposito E, Mazzon E, et al. The effects of a polyphenol present in olive oil, oleuropein aglycone, in an experimental model of spinal cord injury in mice. Biochem Pharmacol. 2012;83(10):1413–1426. doi:10.1016/j.bcp.2012.02.00122342994
   PubMed Web of Science ®Google Scholar
• Khalatbary AR, Ahmadvand H. Neuroprotective effect of oleuropein following spinal cord injury in rats. Neurol Res. 2012;34(1):44–51. doi:10.1179/1743132811Y.000000005822196861
   PubMed Web of Science ®Google Scholar
• Rigacci S, Guidotti V, Bucciantini M, et al. Oleuropein aglycon prevents cytotoxic amyloid aggregation of human amylin☆. J Nutr Biochem. 2010;21(8):726–735. doi:10.1016/j.jnutbio.2009.04.01019616928
   PubMed Web of Science ®Google Scholar
• Luccarini I, Grossi C, Rigacci S, et al. Oleuropein aglycone protects against pyroglutamylated-3 amyloid-ß toxicity: biochemical, epigenetic and functional correlates. Neurobiol Aging. 2015;36(2):648–663. doi:10.1016/j.neurobiolaging.2014.08.02925293421
   PubMed Web of Science ®Google Scholar
• Pasban-Aliabadi H, Esmaeili-Mahani S, Sheibani V, Abbasnejad M, Mehdizadeh A, Yaghoobi MM. Inhibition of 6-hydroxydopamine-induced PC12 cell apoptosis by olive (Olea europaea L.) leaf extract is performed by its main component oleuropein. Rejuvenation Res. 2013;16(2):134–142. doi:10.1089/rej.2012.138423394606
   PubMed Web of Science ®Google Scholar
• Visioli F, Galli C, Galli G, Caruso D. Biological activities and metabolic fate of olive oil phenols. Eur J Lipid Sci Tech. 2002;104:677–684. doi:10.1002/1438-9312(200210)104:9/10<677::AID-EJLT677>3.0.CO;2-M
   Web of Science ®Google Scholar
• Boskou D. Olive Oil: Chemistry and Technology. 2nd ed. AOCS Publishing; 2006.
   Google Scholar
• de la Puerta R, MEM D, Ruíz-Gutíerrez V, Flavill JA, Hoult JRS. Effects of virgin olive oil phenolics on scavenging of reactive nitrogen species and upon nitrergic neurotransmission. Life Sci. 2001;69:1213–1222. doi:10.1016/s0024-3205(01)01218-811508353
   PubMed Web of Science ®Google Scholar
• Visioli F, Caruso D, Galli C, Viappiani S, Galli G, Sala A. Olive oils rich in natural catecholic phenols decrease isoprostane excretion in humans. Biochem Biophys Res Commun. 2000;278:797–799. doi:10.1006/bbrc.2000.387911095986
   PubMed Web of Science ®Google Scholar
• Coni E, Di Benedetto R, Di Pasquale M, et al. Protective effect of oleuropein, an olive oil biophenol, on low density lipoprotein oxidizability in rabbits. Lipids. 2000;35:45–54. doi:10.1007/s11745-000-0493-210695923
   PubMed Web of Science ®Google Scholar
• de la Puerta R, Gutierrez VR, Hoult JRS. Inhibition of leukocyte 5-lipoxygenase by phenolics from virgin olive oil. Biochem Pharmacol. 1999;57:445–449. doi:10.1016/s0006-2952(98)00320-79933033
   PubMed Web of Science ®Google Scholar
• Carluccio MA, Siculella L, Ancora MA, et al. Olive oil and red wine antioxidant polyphenols inhibit endothelial activation: antiatherogenic properties of Mediterranean diet phytochemicals. Arterioscler Thromb Vasc Biol. 2003;23:622–629. doi:10.1161/01.ATV.0000062884.69432.A012615669
   PubMed Web of Science ®Google Scholar
• Hamdi HK, Castellon R. Oleuropein, a non-toxic olive iridoid, is an anti-tumor agent and cytoskeleton disruptor. Biochem Biophys Res Commun. 2005;334:769–778. doi:10.1016/j.bbrc.2005.06.16116024000
   PubMed Web of Science ®Google Scholar
• Menendez JA, Vazquez-Martin A, Colomer R, et al. Olive oil’s bitter principle reverses acquired autoresistance to trastuzumab (Herceptin™) in HER2-overexpressing breast cancer cells. BMC Cancer. 2007;7:80. doi:10.1186/1471-2407-7-8017490486
   PubMed Web of Science ®Google Scholar
• Han J, Talorete TPN, Yamada P, Isoda H. Anti-proliferative and apoptotic effects of oleuropein and hydroxytyrosol on human breast cancer MCF-7 cells. Cytotechnology. 2009;59:45–53. doi:10.1007/s10616-009-9191-219353300
   PubMed Web of Science ®Google Scholar
• Goulas V, Exarchou V, Troganis AN, et al. Phytochemicals in olive-leaf extracts and their antiproliferative activity against cancer and endothelial cells. Mol Nutr Food Res. 2009;53:600–608. doi:10.1002/mnfr.20080020419194970
   PubMed Web of Science ®Google Scholar
• Bisignano G, Tomaino A, Cascio RL, Crisafi G, Uccella N, Saija A. On the in-vitro antimicrobial activity of oleuropein and hydroxytyrosol. J Pharm Pharmacol. 1999;51:971–974. doi:10.1211/002235799177325810504039
   PubMed Web of Science ®Google Scholar
• Aziz NH, Farag SE, Mousa LA, Abo-Zaid MA. Comparative antibacterial and antifungal effects of some phenolic compounds. Microbios. 1998;93:43–54.9670554
   PubMedGoogle Scholar
• Furneri PM, Marino A, Saija A, Uccella N, Bisignano G. In vitro antimycoplasmal activity of oleuropein. Int J Antimicrob Agents. 2002;20:293–296. doi:10.1016/s0924-8579(02)00181-412385687
   PubMed Web of Science ®Google Scholar
• Sudjana AN, D’Orazio C, Ryan V, et al. Antimicrobial activity of commercial Olea europaea (olive) leaf extract. Int J Antimicrob Agents. 2009;33:461–463. doi:10.1016/j.ijantimicag.2008.10.02619135874
   PubMed Web of Science ®Google Scholar
• Tassou CC, Nychas GJ, Board RG. Effect of phenolic compounds and oleuropein on the germination of bacillus cereus T spores. Biotechnol Appl Biochem. 1991;13:231–237.1904245
   PubMed Web of Science ®Google Scholar
• Tassou CC, Nychas GJE. Inhibition of salmonella enteritidis by oleuropein in broth and in a model food system. Lett Appl Microbiol. 1995;20:120–124. doi:10.1111/j.1472-765x.1995.tb01301.x7765901
   PubMed Web of Science ®Google Scholar
• Tassou CC, Nychas GJE. Inhibition of staphylococcus aureus by olive phenolics in broth and in a model food system. J Food Prot. 1994;57:120–124. doi:10.4315/0362-028X-57.2.12031113152
   PubMed Web of Science ®Google Scholar
• Tranter HS, Tassou SC, Nychas GJ. The effect of the olive phenolic compound, oleuropein, on growth and enterotoxin B production by staphylococcus aureus. J Appl Bacteriol. 1993;74:253–259. doi:10.1111/j.1365-2672.1993.tb03023.x8468258
   PubMedGoogle Scholar
• Fredrickson WRF, S Group, Inc. Method and composition for antiviral therapy with olive leaves. U.S. Patent 2000; 6:117:884.
   Google Scholar
• Ma SC, He ZD, Deng XL, et al. In vitro evaluation of secoiridoid glucosides from the fruits of ligustrum lucidum as antiviral agents. Chem Pharm Bull (Tokyo). 2001;49:1471–1473. doi:10.1248/cpb.49.147111724241
   PubMed Web of Science ®Google Scholar