Alterations Of Glycerophospholipid And Fatty Acyl Metabolism In Multiple Brain Regions Of Schizophrenia Microbiota Recipient Mice

References

• Lysaker PH, Gumley A, Luedtke B, et al. Social cognition and metacognition in schizophrenia: evidence of their independence and linkage with outcomes. Acta Psychiatr Scand. 2013;127(3):239–247. doi:10.1111/acps.2013.127.issue-322967227
   PubMed Web of Science ®Google Scholar
• Jin H, Mosweu I. The societal cost of schizophrenia: a systematic review. PharmacoEconomics. 2017;35(1):25–42. doi:10.1007/s40273-016-0444-627557994
   PubMed Web of Science ®Google Scholar
• Mumtaz F, Khan MI, Zubair M, Dehpour AR. Neurobiology and consequences of social isolation stress in animal model-A comprehensive review. Biomed Pharmacother. 2018;105:1205–1222. doi:10.1016/j.biopha.2018.05.08630021357
   PubMed Web of Science ®Google Scholar
• Zhuo C, Yao Y, Xu Y, et al. Schizophrenia and gut-flora related epigenetic factors. Prog Neuropsychopharmacol Biol Psychiatry. 2019;90:49–54. doi:10.1016/j.pnpbp.2018.11.00530419320
   PubMed Web of Science ®Google Scholar
• Prata J, Santos SG, Almeida MI, Coelho R, Barbosa MA. Bridging Autism Spectrum Disorders and Schizophrenia through inflammation and biomarkers - pre-clinical and clinical investigations. J Neuroinflammation. 2017;14(1):179.28870209
   PubMed Web of Science ®Google Scholar
• Yang AC, Tsai S-J. New targets for schizophrenia treatment beyond the dopamine hypothesis. Int J Mol Sci. 2017;18(8):1689. doi:10.3390/ijms18081689
   PubMed Web of Science ®Google Scholar
• Whitton L, Cosgrove D, Clarkson C, et al. Cognitive analysis of schizophrenia risk genes that function as epigenetic regulators of gene expression. Am J Med Genet B Neuropsychiatr Genet. 2016;171(8):1170–1179. doi:10.1002/ajmg.b.3250327762073
   PubMed Web of Science ®Google Scholar
• Xu L, Qi X, Zhu C, Wan L. Activation of IL-8 and its participation in cancer in schizophrenia patients: new evidence for the autoimmune hypothesis of schizophrenia. Neuropsychiatr Dis Treat. 2018;14:3393–3403. doi:10.2147/NDT.S18821030587991
   PubMed Web of Science ®Google Scholar
• Rosa CP, Brancaglion GA, Miyauchi-Tavares TM, Corsetti PP, de Almeida LA. Antibiotic-induced dysbiosis effects on the murine gastrointestinal tract and their systemic repercussions. Life Sci. 2018;207:480–491. doi:10.1016/j.lfs.2018.06.03030056862
   PubMed Web of Science ®Google Scholar
• Lozupone CA, Stombaugh JI, Gordon JI, Jansson JK, Knight R. Diversity, stability and resilience of the human gut microbiota. Nature. 2012;489(7415):220–230. doi:10.1038/nature1155022972295
   PubMed Web of Science ®Google Scholar
• Mayer EA, Tillisch K, Gupta A. Gut/brain axis and the microbiota. J Clin Invest. 2015;125(3):926–938. doi:10.1172/JCI7630425689247
   PubMed Web of Science ®Google Scholar
• Pan JX, Deng FL, Zeng BH, et al. Absence of gut microbiota during early life affects anxiolytic behaviors and monoamine neurotransmitters system in the hippocampal of mice. J Neurol Sci. 2019;400:160–168. doi:10.1016/j.jns.2019.03.02730954660
   PubMed Web of Science ®Google Scholar
• Zheng P, Zeng B, Zhou C, et al. Gut microbiome remodeling induces depressive-like behaviors through a pathway mediated by the host’s metabolism. Mol Psychiatry. 2016;21(6):786–796. doi:10.1038/mp.2016.4427067014
   PubMed Web of Science ®Google Scholar
• Sherwin E, Sandhu KV, Dinan TG, Cryan JF. May the force be with you: the light and dark sides of the microbiota-gut-brain axis in neuropsychiatry. CNS Drugs. 2016;30(11):1019–1041. doi:10.1007/s40263-016-0370-327417321
   PubMed Web of Science ®Google Scholar
• Hemmings G. Schizophrenia. Lancet. 2004;364(9442):1312–1313. doi:10.1016/S0140-6736(04)17181-X
   PubMed Web of Science ®Google Scholar
• Zheng P, Zeng B, Liu M, et al. The gut microbiome from patients with schizophrenia modulates the glutamate-glutamine-GABA cycle and schizophrenia-relevant behaviors in mice. Sci Adv. 2019;5(2):eaau8317. doi:10.1126/sciadv.aau831730775438
   PubMed Web of Science ®Google Scholar
• Sigurdsson T. Neural circuit dysfunction in schizophrenia: insights from animal models. Neuroscience. 2016;321:42–65. doi:10.1016/j.neuroscience.2015.06.05926151679
   PubMed Web of Science ®Google Scholar
• Cao H, Dixson L, Meyer-Lindenberg A, Tost H. Functional connectivity measures as schizophrenia intermediate phenotypes: advances, limitations, and future directions. Curr Opin Neurobiol. 2016;36:7–14. doi:10.1016/j.conb.2015.07.00826276700
   PubMed Web of Science ®Google Scholar
• Lett TA, Voineskos AN, Kennedy JL, Levine B, Daskalakis ZJ. Treating working memory deficits in schizophrenia: a review of the neurobiology. Biol Psychiatry. 2014;75(5):361–370. doi:10.1016/j.biopsych.2013.07.02624011822
   PubMed Web of Science ®Google Scholar
• Viana J, Hannon E, Dempster E, et al. Schizophrenia-associated methylomic variation: molecular signatures of disease and polygenic risk burden across multiple brain regions. Hum Mol Genet. 2017;26(1):210–225. doi:10.1093/hmg/ddw37328011714
   PubMed Web of Science ®Google Scholar
• Errico F, Napolitano F, Squillace M, et al. Decreased levels of D-aspartate and NMDA in the prefrontal cortex and striatum of patients with schizophrenia. J Psychiatr Res. 2013;47(10):1432–1437. doi:10.1016/j.jpsychires.2013.06.01323835041
   PubMed Web of Science ®Google Scholar
• Schmahmann JD. The role of the cerebellum in cognition and emotion: personal reflections since 1982 on the dysmetria of thought hypothesis, and its historical evolution from theory to therapy. Neuropsychol Rev. 2010;20(3):236–260. doi:10.1007/s11065-010-9142-x20821056
   PubMed Web of Science ®Google Scholar
• Sathyanesan A, Zhou J, Scafidi J, Heck DH, Sillitoe RV, Gallo V. Emerging connections between cerebellar development, behaviour and complex brain disorders. Nat Rev Neurosci. 2019;20(5):298–313. doi:10.1038/s41583-019-0152-230923348
   PubMed Web of Science ®Google Scholar
• Chung US, Han DH, Shin YJ, Renshaw PF. A prosocial online game for social cognition training in adolescents with high-functioning autism: an fMRI study. Neuropsychiatr Dis Treat. 2016;12:651–660. doi:10.2147/NDT.S9466927051288
   PubMed Web of Science ®Google Scholar
• Lei Y, Li D, Deng J, et al. Metabolomic profiling of three brain regions from a postnatal infected Borna disease virus Hu-H1 rat model. Metabolomics. 2013;10(3):484–495. doi:10.1007/s11306-013-0593-y
   Web of Science ®Google Scholar
• Zheng P, Wei Y-D, Yao G-E, et al. Novel urinary biomarkers for diagnosing bipolar disorder. Metabolomics. 2013;9(4):800–808. doi:10.1007/s11306-013-0508-y
   Web of Science ®Google Scholar
• Sui J, Pearlson GD, Du Y, et al. In search of multimodal neuroimaging biomarkers of cognitive deficits in schizophrenia. Biol Psychiatry. 2015;78(11):794–804. doi:10.1016/j.biopsych.2015.02.01725847180
   PubMed Web of Science ®Google Scholar
• Carass A, Cuzzocreo JL, Han S, et al. Comparing fully automated state-of-the-art cerebellum parcellation from magnetic resonance images. NeuroImage. 2018;183:150–172. doi:10.1016/j.neuroimage.2018.08.00330099076
   PubMed Web of Science ®Google Scholar
• McCutcheon RA, Abi-Dargham A, Howes OD. Schizophrenia, dopamine and the striatum: from biology to symptoms. Trends Neurosci. 2019;42(3):205–220. doi:10.1016/j.tins.2018.12.00430621912
   PubMed Web of Science ®Google Scholar
• Zhuo K, Tang Y, Song Z, et al. Repetitive transcranial magnetic stimulation as an adjunctive treatment for negative symptoms and cognitive impairment in patients with schizophrenia: a randomized, double-blind, sham-controlled trial. Neuropsychiatr Dis Treat. 2019;15:1141–1150. doi:10.2147/NDT.S19608631190822
   PubMed Web of Science ®Google Scholar
• Ziegler AB, Tavosanis G. Glycerophospholipids - emerging players in neuronal dendrite branching and outgrowth. Dev Biol. 2018.
   Web of Science ®Google Scholar
• Meltzer S, Bagley JA, Perez GL, et al. Phospholipid homeostasis regulates dendrite morphogenesis in drosophila sensory neurons. Cell Rep. 2017;21(4):859–866. doi:10.1016/j.celrep.2017.09.08929069593
   PubMed Web of Science ®Google Scholar
• Konopaske GT, Lange N, Coyle JT, Benes FM. Prefrontal cortical dendritic spine pathology in schizophrenia and bipolar disorder. JAMA Psychiatry. 2014;71(12):1323–1331. doi:10.1001/jamapsychiatry.2014.158225271938
   PubMed Web of Science ®Google Scholar
• Hill JJ, Hashimoto T, Lewis DA. Molecular mechanisms contributing to dendritic spine alterations in the prefrontal cortex of subjects with schizophrenia. Mol Psychiatry. 2006;11(6):557–566. doi:10.1038/sj.mp.400179216402129
   PubMed Web of Science ®Google Scholar
• Fahy E, Subramaniam S, Brown HA, et al. A comprehensive classification system for lipids. J Lipid Res. 2005;46(5):839–861. doi:10.1194/jlr.E400004-JLR20015722563
   PubMed Web of Science ®Google Scholar
• Xicoy H, Wieringa B, Martens GJM. The role of lipids in Parkinson’s disease. Cells. 2019;8(1):27. doi:10.3390/cells8010027
   PubMed Web of Science ®Google Scholar
• Huang Y, Huang S, Lam SM, Liu Z, Shui G, Zhang YQ. Acsl, the Drosophila ortholog of intellectual-disability-related ACSL4, inhibits synaptic growth by altered lipids. J Cell Sci. 2016;129(21):4034–4045. doi:10.1242/jcs.19503227656110
   PubMed Web of Science ®Google Scholar
• Su HM. Mechanisms of n-3 fatty acid-mediated development and maintenance of learning memory performance. J Nutr Biochem. 2010;21(5):364–373. doi:10.1016/j.jnutbio.2009.11.00320233652
   PubMed Web of Science ®Google Scholar
• Yamada D, Wada K, Sekiguchi M. Modulation of long-term potentiation of cortico-amygdala synaptic responses and auditory fear memory by dietary polyunsaturated fatty acid. Front Behav Neurosci. 2016;10:164. doi:10.3389/fnbeh.2016.0016427601985
   PubMed Web of Science ®Google Scholar
• Saumweber T, Weyhersmuller A, Hallermann S, et al. Behavioral and synaptic plasticity are impaired upon lack of the synaptic protein SAP47. J Neurosci. 2011;31(9):3508–3518. doi:10.1523/JNEUROSCI.2646-10.201121368063
   PubMed Web of Science ®Google Scholar
• Sanderson TM, Cotel MC, O’Neill MJ, Tricklebank MD, Collingridge GL, Sher E. Alterations in hippocampal excitability, synaptic transmission and synaptic plasticity in a neurodevelopmental model of schizophrenia. Neuropharmacology. 2012;62(3):1349–1358. doi:10.1016/j.neuropharm.2011.08.00521854789
   PubMed Web of Science ®Google Scholar
• Patten AR, Sickmann HM, Dyer RA, Innis SM, Christie BR. Omega-3 fatty acids can reverse the long-term deficits in hippocampal synaptic plasticity caused by prenatal ethanol exposure. Neurosci Lett. 2013;551:7–11. doi:10.1016/j.neulet.2013.05.05123872044
   PubMed Web of Science ®Google Scholar
• Kobayashi K, Takagi T, Ishii S, Suzuki H, Miyakawa T. Attenuated bidirectional short-term synaptic plasticity in the dentate gyrus of Schnurri-2 knockout mice, a model of schizophrenia. Mol Brain. 2018;11(1):56. doi:10.1186/s13041-018-0400-930285890
   PubMed Web of Science ®Google Scholar
• Khot V, Chavan-Gautam P, Joshi S. Proposing interactions between maternal phospholipids and the one carbon cycle: a novel mechanism influencing the risk for cardiovascular diseases in the offspring in later life. Life Sci. 2015;129:16–21. doi:10.1016/j.lfs.2014.09.02625283080
   PubMed Web of Science ®Google Scholar
• Rangel-Huerta OD, Pastor-Villaescusa B, Gil A. Are we close to defining a metabolomic signature of human obesity? A systematic review of metabolomics studies. Metabolomics. 2019;15(6):93. doi:10.1007/s11306-019-1553-y31197497
   PubMed Web of Science ®Google Scholar
• Schmitt A, Maras A, Petroianu G, Braus DF, Scheuer L, Gattaz WF. Effects of antipsychotic treatment on membrane phospholipid metabolism in schizophrenia. J Neural Transm. 2001;108(8–9):1081–1091. doi:10.1007/s00702017002611716143
   PubMed Web of Science ®Google Scholar
• Ghosh S, Dyer RA, Beasley CL. Evidence for altered cell membrane lipid composition in postmortem prefrontal white matter in bipolar disorder and schizophrenia. J Psychiatr Res. 2017;95:135–142. doi:10.1016/j.jpsychires.2017.08.00928843843
   PubMed Web of Science ®Google Scholar
• Ng QX, Soh AYS, Venkatanarayanan N, Ho CYX, Lim DY, Yeo WS. A systematic review of the effect of probiotic supplementation on schizophrenia symptoms. Neuropsychobiology. 2019;78(1):1–6. doi:10.1159/00049886230947230
   PubMed Web of Science ®Google Scholar
• Ng QX, Peters C, Ho CYX, Lim DY, Yeo WS. A meta-analysis of the use of probiotics to alleviate depressive symptoms. J Affect Disord. 2018;228:13–19. doi:10.1016/j.jad.2017.11.06329197739
   PubMed Web of Science ®Google Scholar
• Zhang B, Zhang H, Du C, et al. Metabolic responses of the growing Daphnia similis to chronic AgNPs exposure as revealed by GC-Q-TOF/MS and LC-Q-TOF/MS. Water Res. 2017;114:135–143. doi:10.1016/j.watres.2017.02.04628237781
   PubMed Web of Science ®Google Scholar