Minimally invasive biomarker confirms glial activation present in Alzheimer’s disease: a preliminary study

References

• KimSSwaminathanSShenLGenome-wide association study of CSF biomarkers Abeta 1–42 t-tau, and p-tau181p in the ADNI cohortNeurology2011761697921123754
   PubMed Web of Science ®Google Scholar
• ShawLMVandersticheleHKnapik-CzajkaMQualification of the analytical and clinical performance of CSF biomarker analyses in ADNIActa Neuropathol2011121559760921311900
   PubMed Web of Science ®Google Scholar
• KrauseDLMullerNNeuroinflammation, microglia and implications for anti-inflammatory treatment in Alzheimer’s diseaseInt J Alzheimers Dis2010201073280620798769
   PubMedGoogle Scholar
• JackCRJrKnopmanDSJagustWJHypothetical model of dynamic biomarkers of the Alzheimer’s pathological cascadeLancet Neurol20109111912820083042
   PubMed Web of Science ®Google Scholar
• GodboltAKWaldmanADMacManusDGMRS shows abnormalities before symptoms in familial Alzheimer diseaseNeurology200666571872216534109
   PubMed Web of Science ®Google Scholar
• RossBDBlumlSCowanRDanielsenEFarrowNGruetterRIn vivo magnetic resonance spectroscopy of human brain: the biophysical basis of dementiaBiophys Chem1997681–31611729468618
   PubMed Web of Science ®Google Scholar
• RossBDDanielsenERBlumlSProton magnetic resonance spectroscopy: the new gold standard for diagnosis of clinical and sub-clinical hepatic encephalopathy?Dig Dis.199614Suppl 130398872450
   PubMed Web of Science ®Google Scholar
• RossBTranTBhattacharyaPWattersonDMSailasutaNApplication of NMR spectroscopy in medicinal chemistry and drug discoveryCurr Top Med Chem20111119311420809893
   PubMed Web of Science ®Google Scholar
• RossBLinAHarrisKBhattacharyaPSchweinsburgBClinical experience with 13C MRS in vivoNMR Biomed2003166–735836914679500
   PubMed Web of Science ®Google Scholar
• LebonVPetersenKFClineGWAstroglial contribution to brain energy metabolism in humans revealed by 13C nuclear magnetic resonance spectroscopy: elucidation of the dominant pathway for neurotransmitter glutamate repletion and measurement of astrocytic oxidative metabolismJ Neurosci20022251523153111880482
   PubMed Web of Science ®Google Scholar
• RothmanDLBeharKLHyderFShulmanRGIn vivo NMR studies of the glutamate neurotransmitter flux and neuroenergetics: implications for brain functionAnnu Rev Physiol20036540142712524459
   PubMed Web of Science ®Google Scholar
• BlumlSMorenoAHwangJHRossBD1-(13)C glucose magnetic resonance spectroscopy of pediatric and adult brain disordersNMR Biomed2001141193211252037
   PubMed Web of Science ®Google Scholar
• BlumlSMoreno-TorresAShicFNguyCHRossBDTricarboxylic acid cycle of glia in the in vivo human brainNMR Biomed20021511511840547
   PubMed Web of Science ®Google Scholar
• SailasutaNAbulseoudOHarrisKCRossBDGlial dysfunction in abstinent methamphetamine abusersJ Cereb Blood Flow Metab201030595096020040926
   PubMed Web of Science ®Google Scholar
• Van den BergCJKrzalicLMelaPWaelschHCompartmentation of glutamate metabolism in brain. Evidence for the existence of two different tricarboxylic acid cycles in brainBiochem J196911322812905808317
   PubMed Web of Science ®Google Scholar
• WyssMTMagistrettiPJBuckAWeberBLabeled acetate as a marker of astrocytic metabolismJ Cereb Blood Flow Metab2011June 8 [Epub ahead of print.]
   Web of Science ®Google Scholar
• MuirDBerlSClarkeDDAcetate and fluoroacetate as possible markers for glial metabolism in vivoBrain Res198638023363403756485
   PubMed Web of Science ®Google Scholar
• BoumezbeurFMasonGFde GraafRAAltered brain mitochondrial metabolism in healthy aging as assessed by in vivo magnetic resonance spectroscopyJ Cereb Blood Flow Metab201030121122119794401
   PubMed Web of Science ®Google Scholar
• SailasutaNTranTTHarrisKCRossBDSwift Acetate Glial Assay (SAGA): an accelerated human (1)(3)C MRS brain exam for clinical diagnostic useJ Magn Reson2010207235235520934362
   PubMed Web of Science ®Google Scholar
• StraussEHShermanEMSSpreenOA compendium of neuropsychological tests3rd edNew YorkOxford University Press2006
   Google Scholar
• PetersenRCMild cognitive impairment as a diagnostic entityJ Intern Med2004256318319415324362
   PubMed Web of Science ®Google Scholar
• SailasutaNRobertsonLWHarrisKCGropmanALAllenPSRossBDClinical NOE 13C MRS for neuropsychiatric disorders of the frontal lobeJ Magn Reson2008195221922518829354
   PubMed Web of Science ®Google Scholar
• SailasutaNAbulseoudOHernandezMHaghaniPRossBDMetabolic abnormalities in abstinent methamphetamine dependent subjectsSubst Abuse20102010492020485533
   PubMedGoogle Scholar
• ProvencherSWEstimation of metabolite concentrations from localized in vivo proton NMR spectraMagn Reson Med19933066726798139448
   PubMed Web of Science ®Google Scholar
• EdenAPriceRWSpudichSFuchsDHagbergLGisslenMImmune activation of the central nervous system is still present after >4 years of effective highly active antiretroviral therapyJ Infect Dis2007196121779178318190258
   PubMed Web of Science ®Google Scholar
• Von GiesenHJWittsackHJWenserskiFKollerHHefterHArendtGBasal ganglia metabolite abnormalities in minor motor disorders associated with human immunodeficiency virus type 1Arch Neurol20015881281128611493169
   PubMedGoogle Scholar
• SekineYOuchiYSugiharaGMethamphetamine causes microglial activation in the brains of human abusersJ Neurosci200828225756576118509037
   PubMed Web of Science ®Google Scholar
• Miguel-HidalgoJJThe role of glial cells in drug abuseCurr Drug Abuse Rev200921728219630738
   PubMedGoogle Scholar
• HiltonGDStoicaBAByrnesKRFadenAIRoscovitine reduces neuronal loss, glial activation, and neurologic deficits after brain traumaJ Cereb Blood Flow Metab200828111845185918612315
   PubMed Web of Science ®Google Scholar
• GraberDJHickeyWFHarrisBTProgressive changes in microglia and macrophages in spinal cord and peripheral nerve in the transgenic rat model of amyotrophic lateral sclerosisJ Neuroinflammation20107820109233
   PubMed Web of Science ®Google Scholar
• EikelenboomPBateCVan GoolWANeuroinflammation in Alzheimer’s disease and prion diseaseGlia200240223223912379910
   PubMed Web of Science ®Google Scholar
• McGeerEGMcGeerPLInflammatory processes in Alzheimer’s diseaseProg Neuropsychopharmacol Biol Psychiatry200327574174912921904
   PubMed Web of Science ®Google Scholar
• LinAPShicFEnriquezCRossBDReduced glutamate neurotransmission in patients with Alzheimer’s disease – an in vivo (13)C magnetic resonance spectroscopy studyMAGMA2003161294212695884
   PubMedGoogle Scholar