Association Between Polymorphisms in the 5′ Region of the GALR1 Gene and Schizophrenia in the Northern Chinese Han Population: A Case–Control Study

References

• Casey DA, Rodriguez M, Northcott C, Vickar G, Shihabuddin L. Schizophrenia: medical illness, mortality, and aging. Int J Psychiatry Med. 2011;41(3):245–251. doi:10.2190/PM.41.3.c22073763
   PubMed Web of Science ®Google Scholar
• van Os J, Kapur S. Schizophrenia. Lancet. 2009;374(9690):635–645. doi:10.1016/S0140-6736(09)60995-819700006
   PubMed Web of Science ®Google Scholar
• Tost H, Alam T, Meyer-Lindenberg A. Dopamine and psychosis: theory, pathomechanisms and intermediate phenotypes. Neurosci Biobehav Rev. 2010;34(5):689–700. doi:10.1016/j.neubiorev.2009.06.00519559045
   PubMed Web of Science ®Google Scholar
• Patrick RP, Ames BN. Vitamin D and the omega-3 fatty acids control serotonin synthesis and action, part 2: relevance for ADHD, bipolar disorder, schizophrenia, and impulsive behavior. FASEB J. 2015;29(6):2207–2222. doi:10.1096/fj.14-26834225713056
   PubMed Web of Science ®Google Scholar
• Devon RS, Anderson S, Teague PW, et al. The genomic organisation of the metabotropic glutamate receptor subtype 5 gene, and its association with schizophrenia. Mol Psychiatry. 2001;6(3):311–314. doi:10.1038/sj.mp.400084811326300
   PubMed Web of Science ®Google Scholar
• Sipkova J, Kramarikova I, Hynie S, Klenerova V. The galanin and galanin receptor subtypes, its regulatory role in the biological and pathological functions. Physiol Res. 2017;66(5):729–740. doi:10.33549/physiolres.93357628730831
   PubMed Web of Science ®Google Scholar
• Frederiksen SO, Ekman R, Gottfries CG, Widerlov E, Jonsson S. Reduced concentrations of galanin, arginine vasopressin, neuropeptide Y and peptide YY in the temporal cortex but not in the hypothalamus of brains from schizophrenics. Acta Psychiatr Scand. 1991;83(4):273–277. doi:10.1111/j.1600-0447.1991.tb05539.x1709331
   PubMed Web of Science ®Google Scholar
• Bai YF, Ma HT, Liu LN, et al. Activation of galanin receptor 1 inhibits locus coeruleus neurons via GIRK channels. Biochem Biophys Res Commun. 2018;503(1):79–85. doi:10.1016/j.bbrc.2018.05.18129852172
   PubMed Web of Science ®Google Scholar
• Seutin V, Verbanck P, Massotte L, Dresse A. Galanin decreases the activity of locus coeruleus neurons in vitro. Eur J Pharmacol. 1989;164(2):373–376. doi:10.1016/0014-2999(89)90481-02474450
   PubMed Web of Science ®Google Scholar
• Holmes A, Kinney JW, Wrenn CC, et al. Galanin GAL-R1 receptor null mutant mice display increased anxiety-like behavior specific to the elevated plus-maze. Neuropsychopharmacology. 2003;28(6):1031–1044. doi:10.1038/sj.npp.130016412700679
   PubMed Web of Science ®Google Scholar
• Karlsson RM, Holmes A. Galanin as a modulator of anxiety and depression and a therapeutic target for affective disease. Amino Acids. 2006;31(3):231–239. doi:10.1007/s00726-006-0336-816733616
   PubMed Web of Science ®Google Scholar
• Wang YJ, Li H, Yang YT, et al. Association of galanin and major depressive disorder in the Chinese Han population. PLoS One. 2013;8(5):e64617. doi:10.1371/journal.pone.006461723741354
   PubMed Web of Science ®Google Scholar
• Hokfelt T, Barde S, Xu ZD, et al. Neuropeptide and small transmitter coexistence: fundamental studies and relevance to mental illness. Front Neural Circuits. 2018;12:106.30627087
   PubMed Web of Science ®Google Scholar
• Picciotto MR. Galanin and addiction. Cell Mol Life Sci. 2008;65(12):1872–1879. doi:10.1007/s00018-008-8151-x18500649
   PubMed Web of Science ®Google Scholar
• Genders SG, Scheller KJ, Djouma E. Neuropeptide modulation of addiction: focus on galanin. Neurosci Biobehav Rev. 2018.
   Web of Science ®Google Scholar
• Levran O, Randesi M, Li Y, et al. Drug addiction and stress-response genetic variability: association study in African Americans. Ann Hum Genet. 2014;78(4):290–298. doi:10.1111/ahg.1206424766650
   PubMed Web of Science ®Google Scholar
• Kramvis A, Bukofzer S, Kew MC. Comparison of hepatitis B virus DNA extractions from serum by the QIAamp blood kit, GeneReleaser, and the phenol-chloroform method. J Clin Microbiol. 1996;34(11):2731–2733.8897174
   PubMed Web of Science ®Google Scholar
• Thakkinstian A, McElduff P, D’Este C, Duffy D, Attia J. A method for meta-analysis of molecular association studies. Stat Med. 2005;24(9):1291–1306. doi:10.1002/sim.201015568190
   PubMed Web of Science ®Google Scholar
• Hoenicka J, Garrido E, Ponce G, et al. Sexually dimorphic interaction between the DRD1 and COMT genes in schizophrenia. Am J Med Genet B Neuropsychiatr Genet. 2010;153B(4):948–954. doi:10.1002/ajmg.b.3106520127886
   PubMed Web of Science ®Google Scholar
• Unschuld PG, Ising M, Erhardt A, et al. Polymorphisms in the galanin gene are associated with symptom-severity in female patients suffering from panic disorder. J Affect Disord. 2008;105(1–3):177–184. doi:10.1016/j.jad.2007.05.00617573119
   PubMed Web of Science ®Google Scholar
• Barde S, Ruegg J, Prud’homme J, et al. Alterations in the neuropeptide galanin system in major depressive disorder involve levels of transcripts, methylation, and peptide. Proc Natl Acad Sci U S A. 2016;113(52):E8472–E8481. doi:10.1073/pnas.161782411327940914
   PubMed Web of Science ®Google Scholar
• Lu X, Barr AM, Kinney JW, et al. A role for galanin in antidepressant actions with a focus on the dorsal raphe nucleus. Proc Natl Acad Sci U S A. 2005;102(3):874–879. doi:10.1073/pnas.040889110215647369
   PubMed Web of Science ®Google Scholar
• Fuxe K, Jansson A, Diaz-Cabiale Z, et al. Galanin modulates 5-hydroxytryptamine functions. Focus on galanin and galanin fragment/5-hydroxytryptamine1A receptor interactions in the brain. Ann N Y Acad Sci. 1998;863:274–290. doi:10.1111/j.1749-6632.1998.tb10702.x9928178
   PubMed Web of Science ®Google Scholar
• Weiss JM, Bonsall RW, Demetrikopoulos MK, Emery MS, West CH. Galanin: a significant role in depression? Ann N Y Acad Sci. 1998;863:364–382. doi:10.1111/j.1749-6632.1998.tb10707.x9928183
   PubMed Web of Science ®Google Scholar
• Wrenn CC, Crawley JN. Pharmacological evidence supporting a role for galanin in cognition and affect. Prog Neuropsychopharmacol Biol Psychiatry. 2001;25(1):283–299. doi:10.1016/S0278-5846(00)00156-111263757
   PubMed Web of Science ®Google Scholar
• Holmes A, Picciotto MR. Galanin: a novel therapeutic target for depression, anxiety disorders and drug addiction? CNS Neurol Disord Drug Targets. 2006;5(2):225–232. doi:10.2174/18715270677635960016611095
   PubMedGoogle Scholar
• Kuteeva E, Hokfelt T, Wardi T, Ogren SO. Galanin, galanin receptor subtypes and depression-like behaviour. Exp Suppl. 2010;102:163–181. doi:10.1007/978-3-0346-0228-0_1221299068
   PubMedGoogle Scholar
• Flores-Burgess A, Millon C, Gago B, et al. Galanin (1-15) enhancement of the behavioral effects of Fluoxetine in the forced swimming test gives a new therapeutic strategy against depression. Neuropharmacology. 2017;118:233–241. doi:10.1016/j.neuropharm.2017.03.01028288814
   PubMed Web of Science ®Google Scholar
• Kuteeva E, Hokfelt T, Wardi T, Ogren SO. Galanin, galanin receptor subtypes and depression-like behaviour. Cell Mol Life Sci. 2008;65(12):1854–1863. doi:10.1007/s00018-008-8160-918500640
   PubMed Web of Science ®Google Scholar
• Borroto-Escuela DO, Narvaez M, Marcellino D, et al. Galanin receptor-1 modulates 5-hydroxtryptamine-1A signaling via heterodimerization. Biochem Biophys Res Commun. 2010;393(4):767–772. doi:10.1016/j.bbrc.2010.02.07820171159
   PubMed Web of Science ®Google Scholar
• Millon C, Flores-Burgess A, Narvaez M, et al. A role for galanin N-terminal fragment (1-15) in anxiety- and depression-related behaviors in rats. Int J Neuropsychopharmacol. 2014;18:3.
   Web of Science ®Google Scholar
• Millon C, Flores-Burgess A, Narvaez M, et al. Galanin (1-15) enhances the antidepressant effects of the 5-HT1A receptor agonist 8-OH-DPAT: involvement of the raphe-hippocampal 5-HT neuron system. Brain Struct Funct. 2016;221(9):4491–4504. doi:10.1007/s00429-015-1180-y26792005
   PubMed Web of Science ®Google Scholar
• Berrettini W. Evidence for shared susceptibility in bipolar disorder and schizophrenia. Am J Med Genet C Semin Med Genet. 2003;123C(1):59–64. doi:10.1002/ajmg.c.2001414601037
   PubMed Web of Science ®Google Scholar
• Tsuang MT, Taylor L, Faraone SV. An overview of the genetics of psychotic mood disorders. J Psychiatr Res. 2004;38(1):3–15. doi:10.1016/S0022-3956(03)00096-714690766
   PubMed Web of Science ®Google Scholar
• Eranti SV, MacCabe JH, Bundy H, Murray RM. Gender difference in age at onset of schizophrenia: a meta-analysis. Psychol Med. 2013;43(1):155–167. doi:10.1017/S003329171200089X22564907
   PubMed Web of Science ®Google Scholar
• Georgieva L, Dimitrova A, Nikolov I, et al. Dopamine transporter gene (DAT1) VNTR polymorphism in major psychiatric disorders: family-based association study in the Bulgarian population. Acta Psychiatr Scand. 2002;105(5):396–399. doi:10.1034/j.1600-0447.2002.1o174.x11942948
   PubMed Web of Science ®Google Scholar
• Talkowski ME, Kirov G, Bamne M, et al. A network of dopaminergic gene variations implicated as risk factors for schizophrenia. Hum Mol Genet. 2008;17(5):747–758. doi:10.1093/hmg/ddm34718045777
   PubMed Web of Science ®Google Scholar