MicroRNA as therapeutic targets for treatment of depression

References

• VosTFlaxmanADNaghaviMYears lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010Lancet201238098592163219623245607
   PubMed Web of Science ®Google Scholar
• AndradeLCaraveo-AnduagaJJBerglundPThe epidemiology of major depressive episodes: results from the International Consortium of Psychiatric Epidemiology (ICPE) SurveysInt J Methods Psychiatr Res200312132112830306
   PubMed Web of Science ®Google Scholar
• KesslerRCMcGonagleKAZhaoSLifetime and 12-month prevalence of DSM-III-R psychiatric disorders in the United States. Results from the National Comorbidity SurveyArch Gen Psychiatry19945118198279933
   PubMed Web of Science ®Google Scholar
• WahidFShehzadAKhanTKimYYMicroRNAs: synthesis, mechanism, function, and recent clinical trialsBiochim Biophys Acta20101803111231124320619301
   PubMed Web of Science ®Google Scholar
• HunsbergerJGAustinDRChenGManjiHKMicroRNAs in mental health: from biological underpinnings to potential therapiesNeuromolecular Med200911317318219544012
   PubMed Web of Science ®Google Scholar
• O’ConnorRMDinanTGCryanJFLittle things on which happiness depends: microRNAs as novel therapeutic targets for the treatment of anxiety and depressionMol Psychiatry201217435937622182940
   PubMed Web of Science ®Google Scholar
• DwivediYEvidence demonstrating role of microRNAs in the etiopathology of major depressionJ Chem Neuroanat201142214215621515361
   PubMed Web of Science ®Google Scholar
• Mouillet-RichardSBaudryALaunayJMKellermannOMicroRNAs and depressionNeurobiol Dis201246227227822226785
   PubMed Web of Science ®Google Scholar
• NuttDJRelationship of neurotransmitters to the symptoms of major depressive disorderJ Clin Psychiatry200869Suppl E14718494537
   PubMed Web of Science ®Google Scholar
• CaspiASugdenKMoffittTEInfluence of life stress on depression: moderation by a polymorphism in the 5-HTT geneScience2003301563138638912869766
   PubMed Web of Science ®Google Scholar
• TianJWJiangWLZhongYPreclinical pharmacology of TP1, a novel potent triple reuptake inhibitor with antidepressant propertiesNeuroscience201119612413021925241
   PubMed Web of Science ®Google Scholar
• HercherCTureckiGMechawarNThrough the looking glass: examining neuroanatomical evidence for cellular alterations in major depressionJ Psychiatr Res2009431194796119233384
   PubMed Web of Science ®Google Scholar
• KemptonMJSalvadorZMunafòMRStructural neuroimaging studies in major depressive disorder. Meta-analysis and comparison with bipolar disorderArch Gen Psychiatry201168767569021727252
   PubMed Web of Science ®Google Scholar
• ArnoneDMcIntoshAMEbmeierKPMunafòMRAndersonIMMagnetic resonance imaging studies in unipolar depression: systematic review and meta-regression analysesEur Neuropsychopharmacol201222111621723712
   PubMed Web of Science ®Google Scholar
• ShelineYIGadoMHKraemerHCUntreated depression and hippocampal volume lossAm J Psychiatry200316081516151812900317
   PubMed Web of Science ®Google Scholar
• HajszanTMacLuskyNJLeranthCShort-term treatment with the antidepressant fluoxetine triggers pyramidal dendritic spine synapse formation in rat hippocampusEur J Neurosci20052151299130315813939
   PubMed Web of Science ®Google Scholar
• HonerWGFalkaiPChenCArangoVMannJJDworkAJSynaptic and plasticity-associated proteins in anterior frontal cortex in severe mental illnessNeuroscience19999141247125510391432
   PubMed Web of Science ®Google Scholar
• MalbergJEEischAJNestlerEJDumanRSChronic antidepressant treatment increases neurogenesis in adult rat hippocampusJ Neurosci200020249104911011124987
   PubMed Web of Science ®Google Scholar
• JacobsBLvan PraagHGageFHAdult brain neurogenesis and psychiatry: a novel theory of depressionMol Psychiatry20005326226910889528
   PubMed Web of Science ®Google Scholar
• HoranWPPoggeDLBorgaroSRStokesJMHarveyPDLearning and memory in adolescent psychiatric inpatients with major depression: a normative study of the California Verbal Learning TestArch Clin Neuropsychol199712657558414590669
   PubMed Web of Science ®Google Scholar
• HashimotoKThe role of glutamate on the action of antidepressantsProg Neuropsychopharmacol Biol Psychiatry20113571558156820600468
   PubMed Web of Science ®Google Scholar
• LiNLiuRJDwyerJMGlutamate N-methyl-D-aspartate receptor antagonists rapidly reverse behavioral and synaptic deficits caused by chronic stress exposureBiol Psychiatry201169875476121292242
   PubMed Web of Science ®Google Scholar
• DumanRSSynaptic plasticity and mood disordersMol Psychiatry20027Suppl 1S29S3411986993
   PubMed Web of Science ®Google Scholar
• PezawasLMeyer-LindenbergAGoldmanALEvidence of biologic epistasis between BDNF and SLC6A4 and implications for depressionMol Psychiatry200813770971618347599
   PubMed Web of Science ®Google Scholar
• SenSDumanRSanacoraGSerum brain-derived neurotrophic factor, depression, and antidepressant medications: meta-analyses and implicationsBiol Psychiatry200864652753218571629
   PubMed Web of Science ®Google Scholar
• ChenBDowlatshahiDMacQueenGMWangJFYoungLTIncreased hippocampal BDNF immunoreactivity in subjects treated with antidepressant medicationBiol Psychiatry200150426026511522260
   PubMed Web of Science ®Google Scholar
• QiXLinWWangDPanYWangWSunMA role for the extracellular signal-regulated kinase signal pathway in depressive-like behaviorBehav Brain Res2009199220320919159647
   PubMed Web of Science ®Google Scholar
• TodorovicCSherrinTPittsMHippelCRaynerMSpiessJSuppression of the MEK/ERK signaling pathway reverses depressionlike behaviors of CRF2-deficient miceNeuropsychopharmacology20093461416142618843268
   PubMed Web of Science ®Google Scholar
• DwivediYRizaviHSZhangHRobertsRCConleyRRPandeyGNAberrant extracellular signal-regulated kinase (ERK)1/2 signalling in suicide brain: role of ERK kinase 1 (MEK1)Int J Neuropsychopharmacol200912101337135419835659
   PubMed Web of Science ®Google Scholar
• GourleySLWuFJKiralyDDRegionally specific regulation of ERK MAP kinase in a model of antidepressant-sensitive chronic depressionBiol Psychiatry200863435335917889834
   PubMed Web of Science ®Google Scholar
• DwivediYRizaviHSConleyRRPandeyGNERK MAP kinase signaling in post-mortem brain of suicide subjects: differential regulation of upstream Raf kinases Raf-1 and B-RafMol Psychiatry2006111869816172610
   PubMed Web of Science ®Google Scholar
• DwivediYRizaviHSRobertsRCConleyRCTammingaCAPandeyGNReduced activation and expression of ERK1/2 MAP kinase in the post-mortem brain of depressed suicide subjectsJ Neurochem200177391692811331420
   PubMed Web of Science ®Google Scholar
• DwivediYRizaviHSTeppenTLower phosphoinositide 3-kinase (PI 3-kinase) activity and differential expression levels of selective catalytic and regulatory PI 3-kinase subunit isoforms in prefrontal cortex and hippocampus of suicide subjectsNeuropsychopharmacology200833102324234018075493
   PubMed Web of Science ®Google Scholar
• SheltonRCSanders-BushEManierDHLewisDAElevated 5-HT 2A receptors in postmortem prefrontal cortex in major depression is associated with reduced activity of protein kinase ANeuroscience200915841406141519111907
   PubMed Web of Science ®Google Scholar
• SheltonRCHal ManierDLewisDAProtein kinases A and C in postmortem prefrontal cortex from persons with major depression and normal controlsInt J Neuropsychopharmacol20091291223123219573263
   PubMed Web of Science ®Google Scholar
• PandeyGNDwivediYPandeySCConleyRRRobertsRCTammingaCAProtein kinase C in the postmortem brain of teenage suicide victimsNeurosci Lett199722821111149209111
   PubMed Web of Science ®Google Scholar
• DwivediYRaoJSRizaviHSAbnormal expression and functional characteristics of cyclic adenosine monophosphate response element binding protein in postmortem brain of suicide subjectsArch Gen Psychiatry200360327328212622660
   PubMed Web of Science ®Google Scholar
• ChenACShirayamaYShinKHNeveRLDumanRSExpression of the cAMP response element binding protein (CREB) in hippocampus produces an antidepressant effectBiol Psychiatry200149975376211331083
   PubMed Web of Science ®Google Scholar
• CotterDRParianteCMEverallIPGlial cell abnormalities in major psychiatric disorders: the evidence and implicationsBrain Res Bull200155558559511576755
   PubMed Web of Science ®Google Scholar
• RajkowskaGMiguel-HidalgoJJGliogenesis and glial pathology in depressionCNS Neurol Disord Drug Targets20076321923317511618
   PubMedGoogle Scholar
• KrishnadasRCavanaghJDepression: an inflammatory illness?J Neurol Neurosurg Psychiatry201283549550222423117
   PubMed Web of Science ®Google Scholar
• DantzerRO’ConnorJCFreundGGJohnsonRWKelleyKWFrom inflammation to sickness and depression: when the immune system subjugates the brainNat Rev Neurosci200891465618073775
   PubMed Web of Science ®Google Scholar
• HowrenMBLamkinDMSulsJAssociations of depression with C-reactive protein, IL-1, and IL-6: a meta-analysisPsychosom Med200971217118619188531
   PubMed Web of Science ®Google Scholar
• DowlatiYHerrmannNSwardfagerWA meta-analysis of cytokines in major depressionBiol Psychiatry201067544645720015486
   PubMed Web of Science ®Google Scholar
• PaceTWMillerAHCytokines and glucocorticoid receptor signaling. Relevance to major depressionAnn N Y Acad Sci200911798610519906234
   PubMed Web of Science ®Google Scholar
• SyvälahtiEEskolaJRuuskanenOLaineTNonsuppression of cortisol in depression and immune functionProg Neuropsychopharmacol Biol Psychiatry1985944134224070644
   PubMed Web of Science ®Google Scholar
• MeltzerHYLowyMTKoenigJIThe hypothalamic-pituitary-adrenal axis in depressionAdv Biochem Psychopharmacol1987431651823035885
   PubMedGoogle Scholar
• MonteleonePMartiadisVMajMCircadian rhythms and treatment implications in depressionProg Neuropsychopharmacol Biol Psychiatry20113571569157420691746
   PubMed Web of Science ®Google Scholar
• MendlewiczJDisruption of the circadian timing systems: molecular mechanisms in mood disordersCNS Drugs200923Suppl 2152619708722
   PubMed Web of Science ®Google Scholar
• KupferDJFosterFGReichLThompsonSKWeissBEEG sleep changes as predictors in depressionAm J Psychiatry19761336622626179333
   PubMed Web of Science ®Google Scholar
• KupferDJREM latency: a psychobiologic marker for primary depressive diseaseBiol Psychiatry1976112159174183839
   PubMed Web of Science ®Google Scholar
• Kaf-De St HilaireSMericaHGaillardJMThe effects of indalpine – a selective inhibitor of 5-HT uptake – on rat paradoxical sleepEur J Pharmacol1984983–44134186233163
   PubMed Web of Science ®Google Scholar
• NicholsonANPascoePA5-Hydroxytryptamine and noradrenaline uptake inhibition: studies on sleep in manNeuropharmacology19862510107910832946975
   PubMed Web of Science ®Google Scholar
• BlissELSleep in schizophrenia and depression: studies of sleep loss in man and animalsRes Publ Assoc Res Nerv Ment Dis1967451952106083190
   PubMedGoogle Scholar
• VogelGWVogelFMcAbeeRSThurmondAJImprovement of depression by REM sleep deprivation. New findings and a theoryArch Gen Psychiatry19803732472537362414
   PubMed Web of Science ®Google Scholar
• GeorgotasAMcCueRECooperTBNagachandranNFriedhoffAFactors affecting the delay of antidepressant effect in responders to nortriptyline and phenelzinePsychiatry Res1989281192662234
   PubMed Web of Science ®Google Scholar
• LeeRCFeinbaumRLAmbrosVThe C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14Cell19937558438548252621
   PubMed Web of Science ®Google Scholar
• Lagos-QuintanaMRauhutRYalcinAMeyerJLendeckelWTuschlTIdentification of tissue-specific microRNAs from mouseCurr Biol200212973573912007417
   PubMed Web of Science ®Google Scholar
• WightmanBHaIRuvkunGPosttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegansCell19937558558628252622
   PubMed Web of Science ®Google Scholar
• BartelDPMicroRNAs: genomics, biogenesis, mechanism, and functionCell2004116228129714744438
   PubMed Web of Science ®Google Scholar
• KozomaraAGriffiths-JonesSmiRBase: integrating microRNA annotation and deep-sequencing dataNucleic Acids Res201139Database issueD152D15721037258
   PubMed Web of Science ®Google Scholar
• KimJKrichevskyAGradYIdentification of many microRNAs that copurify with polyribosomes in mammalian neuronsProc Natl Acad Sci USA2004101136036514691248
   PubMed Web of Science ®Google Scholar
• KosikKSThe neuronal microRNA systemNat Rev Neurosci200671291192017115073
   PubMed Web of Science ®Google Scholar
• GiraldezAJCinalliRMGlasnerMEMicroRNAs regulate brain morphogenesis in zebrafishScience2005308572383383815774722
   PubMed Web of Science ®Google Scholar
• CuellarTLDavisTHNelsonPTDicer loss in striatal neurons produces behavioral and neuroanatomical phenotypes in the absence of neurodegenerationProc Natl Acad Sci USA2008105145614561918385371
   PubMed Web of Science ®Google Scholar
• DavisTHCuellarTLKochSMConditional loss of Dicer disrupts cellular and tissue morphogenesis in the cortex and hippocampusJ Neurosci200828174322433018434510
   PubMed Web of Science ®Google Scholar
• ChengHYPappJWVarlamovaOmicroRNA modulation of circadian-clock period and entrainmentNeuron200754581382917553428
   PubMed Web of Science ®Google Scholar
• HansenKFKarelinaKSakamotoKWaymanGAImpeySObrietanKmiRNA-132: a dynamic regulator of cognitive capacityBrain Struct Funct2013218381783122706759
   PubMed Web of Science ®Google Scholar
• HollanderJAImHIAmelioALStriatal microRNA controls cocaine intake through CREB signallingNature2010466730319720220613834
   PubMed Web of Science ®Google Scholar
• BeveridgeNJCairnsMJMicroRNA dysregulation in schizophreniaNeurobiol Dis201246226327122207190
   PubMed Web of Science ®Google Scholar
• CogswellJPWardJTaylorIAIdentification of miRNA changes in Alzheimer’s disease brain and CSF yields putative biomarkers and insights into disease pathwaysJ Alzheimers Dis2008141274118525125
   PubMed Web of Science ®Google Scholar
• Ghahramani SenoMMHuPGwadryFGGene and miRNA expression profiles in autism spectrum disordersBrain Res20111380859720868653
   PubMed Web of Science ®Google Scholar
• HansenKFSakamotoKObrietanKMicroRNAs: a potential interface between the circadian clock and human healthGenome Med2011321021345247
   PubMed Web of Science ®Google Scholar
• MoreauMPBruseSEDavid-RusRBuyskeSBrzustowiczLMAltered microRNA expression profiles in postmortem brain samples from individuals with schizophrenia and bipolar disorderBiol Psychiatry201169218819321183010
   PubMed Web of Science ®Google Scholar
• XuYLiuHLiFA polymorphism in the microRNA-30e precursor associated with major depressive disorder risk and P300 waveformJ Affect Disord20101271–333233620579744
   PubMed Web of Science ®Google Scholar
• PerkinsDOJeffriesCDJarskogLFmicroRNA expression in the prefrontal cortex of individuals with schizophrenia and schizoaffective disorderGenome Biol200782R2717326821
   PubMed Web of Science ®Google Scholar
• SchepelerTHolmAHalveyPAttenuation of the beta-catenin/TCF4 complex in colorectal cancer cells induces several growth-suppressive microRNAs that target cancer promoting genesOncogene201231222750276021963845
   PubMed Web of Science ®Google Scholar
• ZhouRYuanPWangYEvidence for selective microRNAs and their effectors as common long-term targets for the actions of mood stabilizersNeuropsychopharmacology20093461395140518704095
   PubMed Web of Science ®Google Scholar
• EackerSMKeussMJBerezikovEDawsonVLDawsonTMNeuronal activity regulates hippocampal miRNA expressionPLoS One2011610e2506821984899
   PubMed Web of Science ®Google Scholar
• KimAHReimersMMaherBMicroRNA expression profiling in the prefrontal cortex of individuals affected with schizophrenia and bipolar disordersSchizophr Res20101241–318319120675101
   PubMed Web of Science ®Google Scholar
• RongHLiuTBYangKJMicroRNA-134 plasma levels before and after treatment for bipolar maniaJ Psychiatr Res2011451929520546789
   PubMed Web of Science ®Google Scholar
• Bocchio-ChiavettoLMaffiolettiEBettinsoliPBlood microRNA changes in depressed patients during antidepressant treatmentEur Neuropsychopharmacol201323760261122925464
   PubMed Web of Science ®Google Scholar
• OvedKMoragAPasmanik-ChorMGenome-wide miRNA expression profiling of human lymphoblastoid cell lines identifies tentative SSRI antidepressant response biomarkersPharmacogenomics201213101129113922909203
   PubMed Web of Science ®Google Scholar
• MillanMJMicroRNA in the regulation and expression of serotonergic transmission in the brain and other tissuesCurr Opin Pharmacol2011111112221345728
   PubMed Web of Science ®Google Scholar
• BaudryAMouillet-RichardSSchneiderBLaunayJMKellermannOmiR-16 targets the serotonin transporter: a new facet for adaptive responses to antidepressantsScience201032959981537154120847275
   PubMed Web of Science ®Google Scholar
• LaunayJMMouillet-RichardSBaudryAPietriMKellermannORaphe-mediated signals control the hippocampal response to SRI antidepressants via miR-16Transl Psychiatry20111e5622833211
   PubMed Web of Science ®Google Scholar
• JensenKPCovaultJConnerTSTennenHKranzlerHRFurneauxHMA common polymorphism in serotonin receptor 1B mRNA moderates regulation by miR-96 and associates with aggressive human behaviorsMol Psychiatry200914438138918283276
   PubMed Web of Science ®Google Scholar
• GuoAYSunJJiaPZhaoZA novel microRNA and transcription factor mediated regulatory network in schizophreniaBMC Syst Biol201041020156358
   PubMed Web of Science ®Google Scholar
• NumakawaTRichardsMAdachiNKishiSKunugiHHashidoKMicroRNA function and neurotrophin BDNFNeurochem Int201159555155821723895
   PubMed Web of Science ®Google Scholar
• MelliosNHuangHSGrigorenkoARogaevEAkbarianSA set of differentially expressed miRNAs, including miR-30a-5p, act as post-transcriptional inhibitors of BDNF in prefrontal cortexHum Mol Genet200817193030304218632683
   PubMed Web of Science ®Google Scholar
• AngelucciFCroceNSpallettaGParoxetine rapidly modulates the expression of brain-derived neurotrophic factor mRNA and protein in a human glioblastoma-astrocytoma cell linePharmacology2011871–251021178384
   PubMed Web of Science ®Google Scholar
• DowlatshahiDMacQueenGMWangJFYoungLTIncreased temporal cortex CREB concentrations and antidepressant treatment in major depressionLancet19983529142175417559848357
   PubMed Web of Science ®Google Scholar
• ThomeJSakaiNShinKcAMP response element-mediated gene transcription is upregulated by chronic antidepressant treatmentJ Neurosci200020114030403610818138
   PubMed Web of Science ®Google Scholar
• BöerUAlejelTBeimescheSCRE/CREB-driven up-regulation of gene expression by chronic social stress in CRE-luciferase transgenic mice: reversal by antidepressant treatmentPLoS One200725e43117487276
   PubMed Web of Science ®Google Scholar
• SmalheiserNRLugliGRizaviHSMicroRNA expression in rat brain exposed to repeated inescapable shock: differential alterations in learned helplessness vs non-learned helplessnessInt J Neuropsychopharmacol201114101315132521275079
   PubMed Web of Science ®Google Scholar
• RajasethupathyPFiumaraFSheridanRCharacterization of small RNAs in Aplysia reveals a role for miR-124 in constraining synaptic plasticity through CREBNeuron200963680381719778509
   PubMed Web of Science ®Google Scholar
• KleinMELioyDTMaLImpeySMandelGGoodmanRHHomeostatic regulation of MeCP2 expression by a CREB-induced microRNANat Neurosci200710121513151417994015
   PubMed Web of Science ®Google Scholar
• ChengAWangSCaiJRaoMSMattsonMPNitric oxide acts in a positive feedback loop with BDNF to regulate neural progenitor cell proliferation and differentiation in the mammalian brainDev Biol2003258231933312798291
   PubMed Web of Science ®Google Scholar
• ObrietanKGaoXBVan Den PolANExcitatory actions of GABA increase BDNF expression via a MAPK-CREB-dependent mechanism: a positive feedback circuit in developing neuronsJ Neurophysiol20028821005101512163549
   PubMed Web of Science ®Google Scholar
• RemenyiJHunterCJColeCRegulation of the miR-212/132 locus by MSK1 and CREB in response to neurotrophinsBiochem J2010428228129120307261
   PubMed Web of Science ®Google Scholar
• VoNKleinMEVarlamovaOA cAMP-response element binding protein-induced microRNA regulates neuronal morphogenesisProc Natl Acad Sci USA200510245164261643116260724
   PubMed Web of Science ®Google Scholar
• ImpeySDavareMLesiakAAn activity-induced microRNA controls dendritic spine formation by regulating Rac1-PAK signalingMol Cell Neurosci201043114615619850129
   PubMed Web of Science ®Google Scholar
• WaymanGADavareMAndoHAn activity-regulated microRNA controls dendritic plasticity by down-regulating p250GAPProc Natl Acad Sci USA2008105269093909818577589
   PubMed Web of Science ®Google Scholar
• Alvarez-SaavedraMAntounGYanagiyaAmiRNA-132 orchestrates chromatin remodeling and translational control of the circadian clockHum Mol Genet201120473175121118894
   PubMed Web of Science ®Google Scholar
• KadenerSMenetJSSuginoKA role for microRNAs in the Drosophila circadian clockGenes Dev200923182179219119696147
   PubMed Web of Science ®Google Scholar
• XuSWitmerPDLumayagSKovacsBValleDMicroRNA (miRNA) transcriptome of mouse retina and identification of a sensory organspecific miRNA clusterJ Biol Chem200728234250532506617597072
   PubMed Web of Science ®Google Scholar
• NagelRClijstersLAgamiRThe miRNA-192/194 cluster regulates the Period gene family and the circadian clockFEBS J2009276195447545519682069
   PubMed Web of Science ®Google Scholar
• SausESoriaVEscaramísGGenetic variants and abnormal processing of pre-miR-182, a circadian clock modulator, in major depression patients with late insomniaHum Mol Genet201019204017402520656788
   PubMed Web of Science ®Google Scholar
• ClaesSGlucocorticoid receptor polymorphisms in major depressionAnn N Y Acad Sci2009117921622819906242
   PubMed Web of Science ®Google Scholar
• CalabreseFMolteniRRacagniGRivaMANeuronal plasticity: a link between stress and mood disordersPsychoneuroendocrinology200934Suppl 1S208S21619541429
   PubMedGoogle Scholar
• MeersonACacheauxLGoosensKASapolskyRMSoreqHKauferDChanges in brain MicroRNAs contribute to cholinergic stress reactionsJ Mol Neurosci2010401–2475519711202
   PubMed Web of Science ®Google Scholar
• RinaldiAVincentiSDe VitoFStress induces region specific alterations in microRNAs expression in miceBehav Brain Res2010208126526919913057
   PubMed Web of Science ®Google Scholar
• UchidaSNishidaAHaraKCharacterization of the vulnerability to repeated stress in Fischer 344 rats: possible involvement of microRNA-mediated down-regulation of the glucocorticoid receptorEur J Neurosci20082792250226118445216
   PubMed Web of Science ®Google Scholar
• UchidaSHaraKKobayashiAEarly life stress enhances behavioral vulnerability to stress through the activation of REST4-mediated gene transcription in the medial prefrontal cortex of rodentsJ Neurosci20103045150071501821068306
   PubMed Web of Science ®Google Scholar
• ZimmermanGSoreqHReadthrough acetylcholinesterase: a multifaceted inducer of stress reactionsJ Mol Neurosci2006301–219720017192675
   PubMed Web of Science ®Google Scholar
• MeshorerEBrykBToiberDSC35 promotes sustainable stress-induced alternative splicing of neuronal acetylcholinesterase mRNAMol Psychiatry2005101198599716116489
   PubMed Web of Science ®Google Scholar
• ShaltielGHananMWolfYHippocampal microRNA-132 mediates stress-inducible cognitive deficits through its acetylcholinesterase targetBrain Struct Funct20132181597222246100
   PubMed Web of Science ®Google Scholar
• MadrigalJLGarcía-BuenoBCasoJRPérez-NievasBGLezaJCStress-induced oxidative changes in brainCNS Neurol Disord Drug Targets20065556156817073658
   PubMedGoogle Scholar
• VreugdenhilEVerissimoCSMarimanRMicroRNA 18 and 124a down-regulate the glucocorticoid receptor: implications for glucocorticoid responsiveness in the brainEndocrinology200915052220222819131573
   PubMed Web of Science ®Google Scholar
• TurnerJDAltSRCaoLTranscriptional control of the glucocorticoid receptor: CpG islands, epigenetics and moreBiochem Pharmacol201080121860186820599772
   PubMed Web of Science ®Google Scholar
• KawashimaHNumakawaTKumamaruEGlucocorticoid attenuates brain-derived neurotrophic factor-dependent upregulation of glutamate receptors via the suppression of microRNA-132 expressionNeuroscience201016541301131119958814
   PubMed Web of Science ®Google Scholar
• O’ConnorRMO’LearyOFDinanAGokulADinanTGCryanJFStress-induced alterations in hippocampal and amygdalar microR-NAs: effects of lithiumEuropean Neuropsychopharmacology201020AugustS166S167
   Web of Science ®Google Scholar
• LanfordREHildebrandt-EriksenESPetriATherapeutic silencing of microRNA-122 in primates with chronic hepatitis C virus infectionScience2010327596219820119965718
   PubMed Web of Science ®Google Scholar
• MattesJCollisonAPlankMPhippsSFosterPSAntagonism of microRNA-126 suppresses the effector function of TH2 cells and the development of allergic airways diseaseProc Natl Acad Sci USA200910644187041870919843690
   PubMed Web of Science ®Google Scholar
• KumarMSErkelandSJPesterRESuppression of non-small cell lung tumor development by the let-7 microRNA familyProc Natl Acad Sci USA2008105103903390818308936
   PubMed Web of Science ®Google Scholar
• EbertMSNeilsonJRSharpPAMicroRNA sponges: competitive inhibitors of small RNAs in mammalian cellsNat Methods20074972172617694064
   PubMed Web of Science ®Google Scholar
• RaynerKJEsauCCHussainFNInhibition of miR-33a/b in non-human primates raises plasma HDL and lowers VLDL triglyceridesNature2011478736940440722012398
   PubMed Web of Science ®Google Scholar
• TrajkovskiMHausserJSoutschekJMicroRNAs 103 and 107 regulate insulin sensitivityNature2011474735364965321654750
   PubMed Web of Science ®Google Scholar
• HeYZhouYXiQGenetic variations in microRNA processing genes are associated with susceptibility in depressionDNA Cell Biol20123191499150622694265
   PubMed Web of Science ®Google Scholar
• SoutschekJAkincABramlageBTherapeutic silencing of an endogenous gene by systemic administration of modified siRNAsNature2004432701417317815538359
   PubMed Web of Science ®Google Scholar
• HoyerDThakkerDRNattFGlobal down-regulation of gene expression in the brain using RNA interference, with emphasis on monoamine transporters and GPCRs: implications for target characterization in psychiatric and neurological disordersJ Recept Signal Transduct Res2006265–652754717118797
   PubMed Web of Science ®Google Scholar
• ThakkerDRNattFHüskenDNeurochemical and behavioral consequences of widespread gene knockdown in the adult mouse brain by using nonviral RNA interferenceProc Natl Acad Sci USA200410149172701727515569935
   PubMed Web of Science ®Google Scholar
• ThakkerDRNattFHüsken D, et al. siRNA-mediated knockdown of the serotonin transporter in the adult mouse brainMol Psychiatry200510878278971415940298
   PubMed Web of Science ®Google Scholar
• MukherjiSEbertMSZhengGXTsangJSSharpPAvan OudenaardenAMicroRNAs can generate thresholds in target gene expressionNat Genet201143985485921857679
   PubMed Web of Science ®Google Scholar
• ChtartoABockstaelOTshibanguTDewitteOLevivierMTenenbaumLA next step in adeno-associated virus (AAV)-mediated gene therapy for neurological diseases: regulation and targetingBr J Clin Pharmacol Epub1182013
   Web of Science ®Google Scholar
• GraySJNagabhushan KalburgiSMcCownTJJude SamulskiRGlobal CNS gene delivery and evasion of anti-AAV-neutralizing antibodies by intrathecal AAV administration in non-human primatesGene Ther201320445045923303281
   PubMed Web of Science ®Google Scholar
• SamaranchLSalegioEASan SebastianWAdeno-associated virus serotype 9 transduction in the central nervous system of nonhuman primatesHum Gene Ther201223438238922201473
   PubMed Web of Science ®Google Scholar
• BelzeauxRBergonAJeanjeanVResponder and nonresponder patients exhibit different peripheral transcriptional signatures during major depressive episodeTransl Psychiatry20122e18523149449
   PubMed Web of Science ®Google Scholar
• MoMHChenLFuYWangWFuSWCell-free circulating miRNA biomarkers in cancerJ Cancer2012343244823074383
   PubMed Web of Science ®Google Scholar
• KarolinaDSTavintharanSArmugamACirculating miRNA profiles in patients with metabolic syndromeJ Clin Endocrinol Metab20129712E2271E227623032062
   PubMed Web of Science ®Google Scholar
• ZhaoCDongJJiangTEarly second-trimester serum miRNA profiling predicts gestational diabetes mellitusPLoS One201168e2392521887347
   PubMed Web of Science ®Google Scholar
• LeuenbergerNJanNPradervandSRobinsonNSaugyMCirculating microRNAs as long-term biomarkers for the detection of erythropoiesis-stimulating agent abuseDrug Test Anal2011311–1277177622113880
   PubMed Web of Science ®Google Scholar