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ORIGINAL RESEARCH

Predictors of Early Neurological Deterioration and Functional Outcome in Acute Ischemic Stroke: The Importance of Large Artery Disease, Hyperglycemia and Inflammatory Blood Biomarkers

, , , & ORCID Icon
Pages 1993-2002 | Received 10 Mar 2022, Accepted 17 Aug 2022, Published online: 06 Sep 2022

References

  • Nacu A, Bringeland GH, Khanevski A, Thomassen L, Waje-Andreassen U, Naess H. Early neurological worsening in acute ischaemic stroke patients. Acta Neurol Scand. 2016;133(1):25–29. doi:10.1111/ane.12418
  • Seners P, Turc G, Oppenheim C, Baron JC. Incidence, causes and predictors of neurological deterioration occurring within 24 h following acute ischaemic stroke: a systematic review with pathophysiological implications. J Neurol Neurosurg Psychiatry. 2015;86(1):87–94. doi:10.1136/jnnp-2014-308327
  • Geng HH, Wang Q, Li B, et al. Early neurological deterioration during the acute phase as a predictor of long-term outcome after first-ever ischemic stroke. Medicine. 2017;96(51):e9068. doi:10.1097/MD.0000000000009068
  • Ferrari J, Knoflach M, Kiechl S, et al. Early clinical worsening in patients with TIA or minor stroke: the Austrian Stroke Unit Registry. Neurology. 2010;74(2):136–141. doi:10.1212/WNL.0b013e3181c9188b
  • Thanvi B, Treadwell S, Robinson T. Early neurological deterioration in acute ischaemic stroke: predictors, mechanisms and management. Postgrad Med J. 2008;84(994):412–417. doi:10.1136/pgmj.2007.066118
  • Alawneh JA, Moustafa RR, Baron JC. Hemodynamic factors and perfusion abnormalities in early neurological deterioration. Stroke. 2009;40(6):e443–450. doi:10.1161/STROKEAHA.108.532465
  • Kwan J, Hand P. Early neurological deterioration in acute stroke: clinical characteristics and impact on outcome. QJM. 2006;99(9):625–633. doi:10.1093/qjmed/hcl082
  • Wiryadana KA, Supadmanaba IGP, Samatra D. Progress and potential roles blood biomarkers of ischemic stroke in clinical setting. Indones J Biomed Sci. 2017;11(2):19–29. doi:10.15562/ijbs.v11i2.138
  • Saleem Y, Nogueira RG, Rodrigues GM, et al. Acute neurological deterioration in large vessel occlusions and mild symptoms managed medically. Stroke. 2020;51(5):1428–1434. doi:10.1161/STROKEAHA.119.027011
  • Xie X, Xiao J, Wang Y, et al. Predictive model of early neurological deterioration in patients with acute Ischemic stroke: a Retrospective Cohort Study. J Stroke Cerebrovasc Dis. 2021;30(3):105459. doi:10.1016/j.jstrokecerebrovasdis.2020.105459
  • Martin AJ, Price CI. A systematic review and meta-analysis of molecular biomarkers Associated with Early Neurological Deterioration Following Acute Stroke. Cerebrovasc Dis. 2018;46(5–6):230–241. doi:10.1159/000495572
  • Kim JM, Moon J, Ahn SW, Shin HW, Jung KH, Park KY. The etiologies of early neurological deterioration after thrombolysis and risk factors of Ischemia progression. J Stroke Cerebrovasc Dis. 2016;25(2):383–388. doi:10.1016/j.jstrokecerebrovasdis.2015.10.010
  • Seners P, Turc G, Tisserand M, et al. Unexplained early neurological deterioration after intravenous thrombolysis: incidence, predictors, and associated factors. Stroke. 2014;45(7):2004–2009. doi:10.1161/STROKEAHA.114.005426
  • Simonsen CZ, Schmitz ML, Madsen MH, et al. Early neurological deterioration after thrombolysis: clinical and imaging predictors. Int J Stroke. 2016;11(7):776–782. doi:10.1177/1747493016650454
  • Siegler JE, Boehme AK, Albright KC, et al. A proposal for the classification of etiologies of neurologic deterioration after acute ischemic stroke. J Stroke Cerebrovasc Dis. 2013;22(8):e549–556. doi:10.1016/j.jstrokecerebrovasdis.2013.06.012
  • Seners P, Hurford R, Tisserand M, et al. Is unexplained early neurological deterioration after intravenous Thrombolysis Associated With Thrombus Extension? Stroke. 2017;48(2):348–352. doi:10.1161/STROKEAHA.116.015414
  • Roquer J, Rodríguez-Campello A, Gomis M, et al. Acute stroke unit care and early neurological deterioration in ischemic stroke. J Neurol. 2008;255(7):1012–1017. doi:10.1007/s00415-008-0820-z
  • Shimoyama T, Kimura K, Uemura J, Saji N, Shibazaki K. Elevated glucose level adversely affects infarct volume growth and neurological deterioration in non-diabetic stroke patients, but not diabetic stroke patients. Eur J Neurol. 2014;21(3):402–410. doi:10.1111/ene.12280
  • Sumer M, Ozdemir I, Erturk O. Progression in acute ischemic stroke: frequency, risk factors and prognosis. J Clin Neurosci. 2003;10(2):177–180. doi:10.1016/S0967-5868(02)00325-9
  • Ng GJL, Quek AML, Cheung C, Arumugam TV, Seet RCS. Stroke biomarkers in clinical practice: a critical appraisal. Neurochem Int. 2017;107:11–22. doi:10.1016/j.neuint.2017.01.005
  • Pandey A, Shrivastava AK, Saxena K. Neuron specific enolase and c-reactive protein levels in stroke and its subtypes: correlation with degree of disability. Neurochem Res. 2014;39(8):1426–1432. doi:10.1007/s11064-014-1328-9
  • Whiteley W, Wardlaw J, Dennis M, et al. The use of blood biomarkers to predict poor outcome after acute transient ischemic attack or ischemic stroke. Stroke. 2012;43(1):86–91. doi:10.1161/STROKEAHA.111.634089
  • Deng QW, Huang S, Li S, et al. Inflammatory factors as potential markers of early neurological deterioration in acute ischemic stroke patients receiving endovascular therapy - the AISRNA Study. J Inflamm Res. 2021;14:4399–4407. doi:10.2147/JIR.S317147
  • Vila N, Castillo J, Dávalos A, Chamorro A. Proinflammatory cytokines and early neurological worsening in ischemic stroke. Stroke. 2000;31(10):2325–2329. doi:10.1161/01.STR.31.10.2325
  • Seners P, Baron JC. Revisiting ‘progressive stroke’: incidence, predictors, pathophysiology, and management of unexplained early neurological deterioration following acute ischemic stroke. J Neurol. 2018;265(1):216–225. doi:10.1007/s00415-017-8490-3
  • Wigzell O Nationella riktlinjer för vård vid stroke. [National guidelines for stroke care] The Social welfare board of Sweden; 2020. Available from: www.socialstyrelsen.se. Accessed August 18, 2022.
  • Adams HP Jr, Bendixen BH, Kappelle LJ, et al. Classification of subtype of acute ischemic stroke. Definitions for use in a multicenter clinical trial. TOAST. Trial of Org 10172 in Acute Stroke Treatment. Stroke. 1993;24(1):35–41. doi:10.1161/01.STR.24.1.35
  • Dewey HM, Donnan GA, Freeman EJ, et al. Interrater reliability of the National Institutes of health stroke scale: rating by neurologists and nurses in a community-based stroke incidence study. Cerebrovasc Dis. 1999;9(6):323–327. doi:10.1159/000016006
  • Liu P, Liu S, Feng N, Wang Y, Gao Y, Wu J. Association between neurological deterioration and outcomes in patients with stroke. Ann Transl Med. 2020;8(1):4. doi:10.21037/atm.2019.12.36
  • Lee SJ, Lee DG. Distribution of atherosclerotic stenosis determining early neurologic deterioration in acute ischemic stroke. PLoS One. 2017;12(9):e0185314. doi:10.1371/journal.pone.0185314
  • Parsons MW, Barber PA, Desmond PM, et al. Acute hyperglycemia adversely affects stroke outcome: a magnetic resonance imaging and spectroscopy study. Ann Neurol. 2002;52(1):20–28. doi:10.1002/ana.10241
  • Rosso C, Corvol JC, Pires C, et al. Intensive versus subcutaneous insulin in patients with hyperacute stroke: results from the randomized INSULINFARCT trial. Stroke. 2012;43(9):2343–2349. doi:10.1161/STROKEAHA.112.657122
  • Lemkes BA, Hermanides J, Devries JH, Holleman F, Meijers JC, Hoekstra JB. Hyperglycemia: a prothrombotic factor? J Thromb Haemost. 2010;8(8):1663–1669. doi:10.1111/j.1538-7836.2010.03910.x
  • Beard DJ, McLeod DD, Logan CL, et al. Intracranial pressure elevation reduces flow through collateral vessels and the penetrating arterioles they supply. A possible explanation for ‘collateral failure’ and infarct expansion after ischemic stroke. J Cereb Blood Flow Metab. 2015;35(5):861–872. doi:10.1038/jcbfm.2015.2
  • Winbeck K, Poppert H, Etgen T, Conrad B, Sander D. Prognostic relevance of early serial C-reactive protein measurements after first ischemic stroke. Stroke. 2002;33(10):2459–2464. doi:10.1161/01.STR.0000029828.51413.82
  • Irvine HJ, Battey TW, Ostwaldt AC, et al. Early neurological stability predicts adverse outcome after acute ischemic stroke. Int J Stroke. 2016;11(8):882–889. doi:10.1177/1747493016654484
  • Naveen V, Vengamma B, Mohan A, Vanajakshamma V. N-terminal pro-brain natriuretic peptide levels and short term prognosis in acute ischemic stroke. Ann Indian Acad Neurol. 2015;18(4):435–440. doi:10.4103/0972-2327.165478
  • Chen X, Zhan X, Chen M, et al. The prognostic value of combined NT-pro-BNP levels and NIHSS scores in patients with acute ischemic stroke. Intern Med. 2012;51(20):2887–2892. doi:10.2169/internalmedicine.51.8027
  • Chang L, Yan H, Li H, et al. N-terminal probrain natriuretic peptide levels as a predictor of functional outcomes in patients with ischemic stroke. Neuroreport. 2014;25(13):985–990. doi:10.1097/WNR.0000000000000195
  • Katsuki M, Kakizawa Y, Nishikawa A, Yamamoto Y, Uchiyama T. Temporal muscle thickness and area are an independent prognostic factors in patients aged 75 or younger with aneurysmal subarachnoid hemorrhage treated by clipping. Surg Neurol Int. 2021;12:151. doi:10.25259/SNI_814_2020
  • Furtner J, Weller M, Weber M, et al. Temporal muscle thickness as a prognostic marker in patients with newly diagnosed glioblastoma: translational imaging analysis of the CENTRIC EORTC 26071–22072 and CORE Trials. Clin Cancer Res. 2022;28(1):129–136. doi:10.1158/1078-0432.CCR-21-1987
  • Zhang X, Sun Z, Ding C, et al. Metabolic syndrome augments the risk of early neurological deterioration in acute ischemic stroke patients Independent of Inflammatory Mediators: a Hospital-Based Prospective Study. Oxid Med Cell Longev. 2016;2016:8346301. doi:10.1155/2016/8346301
  • Montellano FA, Ungethüm K, Ramiro L, et al. Role of blood-based biomarkers in ischemic stroke prognosis: a systematic review. Stroke. 2021;52(2):543–551. doi:10.1161/STROKEAHA.120.029232
  • Glushakova OY, Glushakov AV, Miller ER, Valadka AB, Hayes RL. Biomarkers for acute diagnosis and management of stroke in neurointensive care units. Brain Circ. 2016;2(1):28–47. doi:10.4103/2394-8108.178546