Advanced search
Publication Cover
Neuropsychiatric Disease and Treatment Volume 18, 2022 - Issue
Submit an article Journal homepage
155
Views
1
CrossRef citations to date
0
Altmetric
ORIGINAL RESEARCH

The Association of IL7R rs6897932 with Risk of Multiple Sclerosis in Southern Chinese

Zongbo ZhaoDepartment of Neurology and Institute of Neurology, The Affiliated Changshu Hospital of Xuzhou Medical University, Suchow, People’s Republic of ChinaView further author information
,
Jianzhong XueDepartment of Neurology and Institute of Neurology, The Affiliated Changshu Hospital of Xuzhou Medical University, Suchow, People’s Republic of ChinaView further author information
,
Ziliang ZhuoDepartment of Neurology and Institute of Neurology, The Affiliated Changshu Hospital of Xuzhou Medical University, Suchow, People’s Republic of ChinaView further author information
,
Wei ZhongDepartment of Neurology and Institute of Neurology, The Affiliated Changshu Hospital of Xuzhou Medical University, Suchow, People’s Republic of ChinaView further author information
&
Hui LiuDepartment of Neurology and Institute of Neurology, The Affiliated Changshu Hospital of Xuzhou Medical University, Suchow, People’s Republic of ChinaCorrespondence[email protected]
View further author information
Pages 1855-1859 | Received 01 Jun 2022, Accepted 17 Aug 2022, Published online: 26 Aug 2022

References

  • Baranzini SE, Oksenberg JR. The genetics of multiple sclerosis: from 0 to 200 in 50 years. Trends Genet. 2017;33:960–970. doi:10.1016/j.tig.2017.09.004
  • Kister I, Bacon TE, Chamot E, et al. Natural history of multiple sclerosis symptoms. Int J MS Care. 2013;15:146–156. doi:10.7224/1537-2073.2012-053
  • Jafarzadeh A, Mahdavi R, Jamali M, et al. Increased concentrations of interleukin-33 in the serum and cerebrospinal fluid of patients with multiple sclerosis. Oman Med J. 2016;31:40–45. doi:10.5001/omj.2016.08
  • Compston A, Coles A. Multiple sclerosis. Lancet. 2008;372:1502–1517. doi:10.1016/s0140-6736(08)61620-7
  • Gregory SG, Schmidt S, Seth P, et al. Interleukin 7 receptor alpha chain (IL7R) shows allelic and functional association with multiple sclerosis. Nat Genet. 2007;39:1083–1091. doi:10.1038/ng2103
  • Fang L, Isobe N, Yoshimura S, et al. Interleukin-7 receptor alpha gene polymorphism influences multiple sclerosis risk in Asians. Neurology. 2011;76:2125–2127. doi:10.1212/WNL.0b013e31821f466c
  • Thompson AJ, Banwell BL, Barkhof F, et al. Diagnosis of multiple sclerosis: 2017 revisions of the McDonald criteria. Lancet Neurol. 2018;17:162–173. doi:10.1016/s1474-4422(17)30470-2
  • Pathak K. The expanding role of IL-7 and thymic stromal lymphopoietin as therapeutic target for rheumatoid arthritis. Expert Opin Ther Targets. 2014;18:581–594. doi:10.1517/14728222.2014.893295
  • Kelly EA, Koziol-White CJ, Clay KJ, et al. Potential contribution of IL-7 to allergen-induced eosinophilic airway inflammation in asthma. J Immunol. 2009;182:1404–1410. doi:10.4049/jimmunol.182.3.1404
  • McKay FC, Swain LI, Schibeci SD, et al. CD127 immunophenotyping suggests altered CD4+ T cell regulation in primary progressive multiple sclerosis. J Autoimmun. 2008;31:52–58. doi:10.1016/j.jaut.2008.02.003
  • Li L, Masucci MG, Levitsky V. Effect of interleukin-7 on the in vitro development and maturation of monocyte derived human dendritic cells. Scand J Immunol. 2000;51:361–371. doi:10.1046/j.1365-3083.2000.00687.x
  • Zhou J, Jin JO, Du J, Yu Q. Innate immune signaling induces IL-7 production, early inflammatory responses, and Sjögren's-like dacryoadenitis in C57BL/6 mice. Invest Ophthalmol Vis Sci. 2015;56:7831. doi:10.1167/iovs.15-17368
  • Arbelaez CA, Glatigny S, Duhen R, et al. IL-7/IL-7 receptor signaling differentially affects effector CD4 + T cell subsets involved in experimental autoimmune encephalomyelitis. J Immunol. 2015;195:1974–1983. doi:10.4049/jimmunol.1403135
  • Mazzucchelli RI, Riva A, Durum SK. The human IL-7 receptor gene: deletions, polymorphisms and mutations. Semin Immunol. 2012;24:225–230. doi:10.1016/j.smim.2012.02.007
  • Ribeiro AR, Rodrigues PM, Meireles C, Di Santo JP, Alves NL. Thymocyte selection regulates the homeostasis of IL-7-expressing thymic cortical epithelial cells in vivo. J Immunol. 2013;191:1200–1209. doi:10.4049/jimmunol.1203042
  • O’Connor AM, Crawley AM, Angel JB. Interleukin-7 enhances memory CD8(+) T-cell recall responses in health but its activity is impaired in human immunodeficiency virus infection. Immunology. 2010;131:525–536. doi:10.1111/j.1365-2567.2010.03325.x
  • Hartling HJ, Thørner LW, Erikstrup C, et al. Polymorphisms in the interleukin-7 receptor α gene and mortality in untreated HIV-infected individuals. Aids. 2013;27:1615–1620. doi:10.1097/QAD.0b013e3283606c2d
  • Hartling HJ, Thørner LW, Erikstrup C, et al. Polymorphism in interleukin-7 receptor α gene is associated with faster CD4+ T-cell recovery after initiation of combination antiretroviral therapy. Aids. 2014;28:1739–1748. doi:10.1097/qad.0000000000000354
  • Wu S, Liu Q, Zhu J-M, et al. Association between the IL7R T244I polymorphism and multiple sclerosis risk: a meta analysis. Neurol Sci. 2016;37:1467–1474. doi:10.1007/s10072-016-2608-8
  • Heidari M, Behmanesh M, Sahraian MA. Variation in SNPs of the IL7Ra gene is associated with multiple sclerosis in the Iranian population. Immunol Invest. 2011;40:279–289. doi:10.3109/08820139.2010.540287
  • Majdinasab N, Hosseini Behbahani M, Galehdari H, Mohaghegh M. Association of interleukin 7 receptor gene polymorphism rs6897932 with multiple sclerosis patients in Khuzestan. Iran J Neurol. 2014;13:168–171.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.