Optimal treatment of Alzheimer’s disease psychosis: challenges and solutions

References

• AarslandDCummingsJLYennerGMillerBRelationship of aggressive behavior to other neuropsychiatric symptoms in patients with Alzheimer’s diseaseAm J Psychiatry199615322432478561206
   PubMed Web of Science ®Google Scholar
• DeutschLHBylsmaFWRovnerBWSteeleCFolsteinMFPsychosis and physical aggression in probable Alzheimer’s diseaseAm J Psychiatry19911489115911631882992
   PubMed Web of Science ®Google Scholar
• KunikMESnow-TurekALIqbalNContribution of psychosis and depression to behavioral disturbances in geropsychiatric inpatients with dementiaJ Gerontol A Biol Sci Med Sci1999543M157M16110191845
   PubMed Web of Science ®Google Scholar
• KnopmanDSKittoJDeinardSHeiringJLongitudinal study of death and institutionalization in patients with primary degenerative dementiaJ Am Geriatr Soc19883621081123339214
   PubMed Web of Science ®Google Scholar
• O’DonnellBFDrachmanDABarnesHJPetersonKESwearerJMLewRAIncontinence and troublesome behaviors predict institutionalization in dementiaJ Geriatr Psychiatry Neurol19925145521571074
   PubMedGoogle Scholar
• GilleyDWWilsonRSBeckettLAEvansDAPsychotic symptoms and physically aggressive behavior in Alzheimer’s diseaseJ Am Geriatr Soc1997459107410799288014
   PubMed Web of Science ®Google Scholar
• MaHHuangYCongZThe efficacy and safety of atypical antipsychotics for the treatment of dementia: a meta-analysis of randomized placebo-controlled trialsJ Alzheimers Dis201442391593725024323
   PubMed Web of Science ®Google Scholar
• OverallJEGorhamDRThe Brief Psychiatric Rating ScalePsychological Report196210799812
   Web of Science ®Google Scholar
• RhoadesHMOverallJEThe semistructured BPRS interview and rating guidePsychopharmacol Bull19882411011043290934
   PubMedGoogle Scholar
• StreetJSClarkWSGannonKSOlanzapine treatment of psychotic and behavioral symptoms in patients with Alzheimer disease in nursing care facilities: a double-blind, randomized, placebo-controlled trial. The HGEU Study GroupArch Gen Psychiatry2000571096897611015815
   PubMed Web of Science ®Google Scholar
• De DeynPPCarrascoMMDeberdtWOlanzapine versus placebo in the treatment of psychosis with or without associated behavioral disturbances in patients with Alzheimer’s diseaseInt J Geriatr Psychiatry200419211512614758577
   PubMed Web of Science ®Google Scholar
• SultzerDLDavisSMTariotPNCATIE-AD Study GroupClinical symptom responses to atypical antipsychotic medications in Alzheimer’s disease: phase 1 outcomes from the CATIE-AD effectiveness trialAm J Psychiatry2008165784485418519523
   PubMed Web of Science ®Google Scholar
• De DeynPJesteDVSwaninkRAripiprazole for the treatment of psychosis in patients with Alzheimer’s disease: a randomized, placebo-controlled studyJ Clin Psychopharmacol200525546346716160622
   PubMed Web of Science ®Google Scholar
• MintzerJETuneLEBrederCDAripiprazole for the treatment of psychoses in institutionalized patients with Alzheimer dementia: a multicenter, randomized, double-blind, placebo-controlled assessment of three fixed dosesAm J Geriatr Psychiatry2007151191893117974864
   PubMed Web of Science ®Google Scholar
• TariotPNSchneiderLKatzIRQuetiapine treatment of psychosis associated with dementia: a double-blind, randomized, placebo-controlled clinical trialAm J Geriatr Psychiatry200614976777616905684
   PubMed Web of Science ®Google Scholar
• KatzIRJesteDVMintzerJEClydeCNapolitanoJBrecherMComparison of risperidone and placebo for psychosis and behavioral disturbances associated with dementia: a randomized, double-blind trial. Risperidone Study GroupJ Clin Psychiatry199960210711510084637
   PubMed Web of Science ®Google Scholar
• De DeynPPRabheruKRasmussenAA randomized trial of risperidone, placebo, and haloperidol for behavioral symptoms of dementiaNeurology199953594695510496251
   PubMed Web of Science ®Google Scholar
• BrodatyHAmesDSnowdonJA randomized placebo-controlled trial of risperidone for the treatment of aggression, agitation, and psychosis of dementiaJ Clin Psychiatry200364213414312633121
   PubMed Web of Science ®Google Scholar
• MintzerJGreenspanACaersIRisperidone in the treatment of psychosis of Alzheimer disease: results from a prospective clinical trialAm J Geriatr Psychiatry200614328029116505133
   PubMed Web of Science ®Google Scholar
• KatzIde DeynPPMintzerJGreenspanAZhuYBrodatyHThe efficacy and safety of risperidone in the treatment of psychosis of Alzheimer’s disease and mixed dementia: a meta-analysis of 4 placebo-controlled clinical trialsInt J Geriatr Psychiatry200722547548417471598
   PubMed Web of Science ®Google Scholar
• SultzerDLPsychosis and antipsychotic medications in Alzheimer’s disease: clinical management and research perspectivesDement Geriatr Cogn Disord2004171–2789014566100
   PubMed Web of Science ®Google Scholar
• FlintAJDelusions in dementia: a reviewJ Neuropsychiatry Clin Neurosci1991321211301687962
   PubMedGoogle Scholar
• SultzerDLLevinHSMahlerMEHighWMCummingsJLAssessment of cognitive, psychiatric, and behavioral disturbances in patients with dementia: the Neurobehavioral Rating ScaleJ Am Geriatr Soc19924065495551587970
   PubMed Web of Science ®Google Scholar
• PaulsenJSSalmonDPThalLJIncidence of and risk factors for hallucinations and delusions in patients with probable ADNeurology200054101965197110822438
   PubMed Web of Science ®Google Scholar
• DevanandDPJacobsDMTangMXThe course of psychopathologic features in mild to moderate Alzheimer diseaseArch Gen Psychiatry19975432572639075466
   PubMed Web of Science ®Google Scholar
• MegaMSCummingsJLFiorelloTGornbeinJThe spectrum of behavioral changes in Alzheimer’s diseaseNeurology19964611301358559361
   PubMed Web of Science ®Google Scholar
• LyketsosCGSteinbergMTschanzJTNortonMCSteffensDCBreitnerJCMental and behavioral disturbances in dementia: findings from the Cache County Study on Memory in AgingAm J Psychiatry2000157570871410784462
   PubMed Web of Science ®Google Scholar
• SweetRANimgaonkarVLDevlinBLopezOLDeKoskySTIncreased familial risk of the psychotic phenotype of Alzheimer diseaseNeurology200258690791111914406
   PubMed Web of Science ®Google Scholar
• BacanuSADevlinBChowdariKVDeKoskySTNimgaonkarVLSweetRAHeritability of psychosis in Alzheimer diseaseAm J Geriatr Psychiatry200513762462716009739
   PubMed Web of Science ®Google Scholar
• SchneiderLSDagermanKSPsychosis of Alzheimer’s disease: clinical characteristics and historyJ Psychiatr Res200438110511114690773
   PubMed Web of Science ®Google Scholar
• CermolacceMSassLParnasJWhat is bizarre in bizarre delusions? A critical reviewSchizophr Bull201036466767920142381
   PubMed Web of Science ®Google Scholar
• ReevesSJGouldRLPowellJFHowardRJOrigins of delusions in Alzheimer’s diseaseNeurosci Biobehav Rev201236102274228722910677
   PubMed Web of Science ®Google Scholar
• CookSEMiyaharaSBacanuSAPsychotic symptoms in Alzheimer disease: evidence for subtypesAm J Geriatr Psychiatry200311440641312837669
   PubMed Web of Science ®Google Scholar
• BurnsAJacobyRLevyRPsychiatric phenomena in Alzheimer’s disease. I: disorders of thought contentBr J Psychiatry1990157727692942397365
   PubMed Web of Science ®Google Scholar
• ReisbergBBorensteinJSalobSPFerrisSHFranssenEGeorgotasABehavioral symptoms in Alzheimer’s disease: phenomenology and treatmentJ Clin Psychiatry198748Suppl9153553166
   PubMed Web of Science ®Google Scholar
• RubinEHDrevetsWCBurkeWJThe nature of psychotic symptoms in senile dementia of the Alzheimer typeJ Geriatr Psychiatry Neurol19881116203266997
   PubMedGoogle Scholar
• BurnsAJacobyRLevyRPsychiatric phenomena in Alzheimer’s disease. II: disorders of perceptionBr J Psychiatry1990157768192942397366
   PubMed Web of Science ®Google Scholar
• MerriamAEAronsonMKGastonPWeySLKatzIThe psychiatric symptoms of Alzheimer’s diseaseJ Am Geriatr Soc19883617123335733
   PubMed Web of Science ®Google Scholar
• GormleyNRizwanMRPrevalence and clinical correlates of psychotic symptoms in Alzheimer’s diseaseInt J Geriatr Psychiatry19981364104149658277
   PubMed Web of Science ®Google Scholar
• HwangJPYangCHTsaiSJPhantom boarder symptom in dementiaInt J Geriatr Psychiatry200318541742012766918
   PubMed Web of Science ®Google Scholar
• VenneriAShanksMFStaffRTDella SalaSNurturing syndrome: a form of pathological bereavement with delusions in Alzheimer’s diseaseNeuropsychologia200038221322410660231
   PubMed Web of Science ®Google Scholar
• RabinsPVMaceNLLucasMJThe impact of dementia on the familyJAMA198224833333357087127
   PubMed Web of Science ®Google Scholar
• JesteDVFinkelSIPsychosis of Alzheimer’s disease and related dementias. Diagnostic criteria for a distinct syndromeAm J Geriatr Psychiatry200081293410648292
   PubMed Web of Science ®Google Scholar
• MurrayPSKumarSDemichele-SweetMASweetRAPsychosis in Alzheimer’s diseaseBiol Psychiatry201475754255224103379
   PubMed Web of Science ®Google Scholar
• CummingsJLMillerBHillMANeshkesRNeuropsychiatric aspects of multi-infarct dementia and dementia of the Alzheimer typeArch Neurol19874443893933827694
   PubMedGoogle Scholar
• HironoNMoriEYasudaMFactors associated with psychotic symptoms in Alzheimer’s diseaseJ Neurol Neurosurg Psychiatry19986456486529598682
   PubMed Web of Science ®Google Scholar
• RopackiSAJesteDVEpidemiology of and risk factors for psychosis of Alzheimer’s disease: a review of 55 studies published from 1990 to 2003Am J Psychiatry2005162112022203016263838
   PubMed Web of Science ®Google Scholar
• BerriosGENon-cognitive symptoms and the diagnosis of dementia. Historical and clinical aspectsBr J Psychiatry Suppl1989411162690875
   PubMedGoogle Scholar
• MalloyPFRichardsonEDThe frontal lobes and content-specific delusionsJ Neuropsychiatry Clin Neurosci1994644554667841816
   PubMed Web of Science ®Google Scholar
• ShakhmatovNFOn psychotic pictures observed during the course of Alzheimer’s disease and Pick’s diseaseZh Nevropatol Psikhiatr Im S S Korsakova196464265269 Russian14140453
   PubMedGoogle Scholar
• MayeuxRSternYSpantonSHeterogeneity in dementia of the Alzheimer type: evidence of subgroupsNeurology19853544534613982631
   PubMed Web of Science ®Google Scholar
• SternYMayeuxRSanoMHauserWABushTPredictors of disease course in patients with probable Alzheimer’s diseaseNeurology19873710164916533658173
   PubMed Web of Science ®Google Scholar
• DrevetsWCRubinEHPsychotic symptoms and the longitudinal course of senile dementia of the Alzheimer typeBiol Psychiatry198925139482912509
   PubMed Web of Science ®Google Scholar
• RosenJZubenkoGSEmergence of psychosis and depression in the longitudinal evaluation of Alzheimer’s diseaseBiol Psychiatry19912932242322015329
   PubMed Web of Science ®Google Scholar
• WilsonRSGilleyDWBennettDABeckettLAEvansDAHallucinations, delusions, and cognitive decline in Alzheimer’s diseaseJ Neurol Neurosurg Psychiatry200069217217710896689
   PubMed Web of Science ®Google Scholar
• EmanuelJELopezOLHouckPRTrajectory of cognitive decline as a predictor of psychosis in early Alzheimer disease in the cardiovascular health studyAm J Geriatr Psychiatry201119216016820808116
   PubMed Web of Science ®Google Scholar
• JesteDVWraggRESalmonDPHarrisMJThalLJCognitive deficits of patients with Alzheimer’s disease with and without delusionsAm J Psychiatry199214921841891734737
   PubMed Web of Science ®Google Scholar
• KoppelJGoldbergTEGordonMLRelationships between behavioral syndromes and cognitive domains in Alzheimer disease: the impact of mood and psychosisAm J Geriatr Psychiatry20122011994100022048323
   PubMed Web of Science ®Google Scholar
• KoppelJSundaySGoldbergTEDaviesPChristenEGreenwaldBSAlzheimer’s Disease Neuroimaging InitiativePsychosis in Alzheimer’s disease is associated with frontal metabolic impairment and accelerated decline in working memory: findings from the Alzheimer’s Disease Neuroimaging InitiativeAm J Geriatr Psychiatry201422769870723672944
   PubMed Web of Science ®Google Scholar
• HuiJSWilsonRSBennettDABieniasJLGilleyDWEvansDARate of cognitive decline and mortality in Alzheimer’s diseaseNeurology200361101356136114638955
   PubMed Web of Science ®Google Scholar
• HeymanAWilkinsonWEHurwitzBJEarly-onset Alzheimer’s disease: clinical predictors of institutionalization and deathNeurology19873769809843587649
   PubMed Web of Science ®Google Scholar
• BurnsALewisGJacobyRLevyRFactors affecting survival in Alzheimer’s diseasePsychol Med19912123633701876641
   PubMed Web of Science ®Google Scholar
• LopezOLWisniewskiSRBeckerJTBollerFDeKoskySTPsychiatric medication and abnormal behavior as predictors of progression in probable Alzheimer diseaseArch Neurol199956101266127210520944
   PubMed Web of Science ®Google Scholar
• SamsonWNvan DuijnCMHopWCHofmanAClinical features and mortality in patients with early-onset Alzheimer’s diseaseEur Neurol19963621031068654478
   PubMed Web of Science ®Google Scholar
• SternYTangMXAlbertMSPredicting time to nursing home care and death in individuals with Alzheimer diseaseJAMA1997277108068129052710
   PubMed Web of Science ®Google Scholar
• MoritzDJFoxPJLuscombeFAKraemerHCNeurological and psychiatric predictors of mortality in patients with Alzheimer disease in CaliforniaArch Neurol19975478788859236577
   PubMedGoogle Scholar
• ScarmeasNBrandtJAlbertMDelusions and hallucinations are associated with worse outcome in Alzheimer diseaseArch Neurol200562101601160816216946
   PubMedGoogle Scholar
• WilsonRSKruegerKRKamenetskyJMHallucinations and mortality in Alzheimer diseaseAm J Geriatr Psychiatry2005131198499016286442
   PubMed Web of Science ®Google Scholar
• Vilalta-FranchJLópez-PousaSCalvó-PerxasLGarre-OlmoJPsychosis of Alzheimer disease: prevalence, incidence, persistence, risk factors, and mortalityAm J Geriatr Psychiatry201321111135114323567368
   PubMed Web of Science ®Google Scholar
• LopezOLBeckerJTChangYFThe long-term effects of conventional and atypical antipsychotics in patients with probable Alzheimer’s diseaseAm J Psychiatry201317091051105823896958
   PubMed Web of Science ®Google Scholar
• MurrayPSKumarSDemichele-SweetMASweetRAPsychosis in Alzheimer’s diseaseBiol Psychiatry201475754255224103379
   PubMed Web of Science ®Google Scholar
• GeroldiCBrescianiLZanettiOFrisoniGBRegional brain atrophy in patients with mild Alzheimer’s disease and delusionsInt Psychogeriatr200214436537812670058
   PubMed Web of Science ®Google Scholar
• BruenPDMcGeownWJShanksMFVenneriANeuroanatomical correlates of neuropsychiatric symptoms in Alzheimer’s diseaseBrain2008131Pt 92455246318669506
   PubMed Web of Science ®Google Scholar
• WhiteheadDTunnardCHurtCAddNeuroMed ConsortiumFrontotemporal atrophy associated with paranoid delusions in women with Alzheimer’s diseaseInt Psychogeriatr20122419910721740613
   PubMed Web of Science ®Google Scholar
• HironoNMoriEIshiiKAlteration of regional cerebral glucose utilization with delusions in Alzheimer’s diseaseJ Neuropsychiatry Clin Neurosci19981044334399813789
   PubMed Web of Science ®Google Scholar
• MentisMJWeinsteinEAHorwitzBAbnormal brain glucose metabolism in the delusional misidentification syndromes: a positron emission tomography study in Alzheimer diseaseBiol Psychiatry19953874384498672604
   PubMed Web of Science ®Google Scholar
• SultzerDLMahlerMEMandelkernMAThe relationship between psychiatric symptoms and regional cortical metabolism in Alzheimer’s diseaseJ Neuropsychiatry Clin Neurosci1995744764848555751
   PubMed Web of Science ®Google Scholar
• LopezOLSmithGBeckerJTMeltzerCCDeKoskySTThe psychotic phenomenon in probable Alzheimer’s disease: a positron emission tomography studyJ Neuropsychiatry Clin Neurosci2001131505511207329
   PubMed Web of Science ®Google Scholar
• GradyCLHaxbyJVSchapiroMBSubgroups in dementia of the Alzheimer type identified using positron emission tomographyJ Neuropsychiatry Clin Neurosci1990243733842136389
   PubMedGoogle Scholar
• SultzerDLBrownCVMandelkernMADelusional thoughts and regional frontal/temporal cortex metabolism in Alzheimer’s diseaseAm J Psychiatry2003160234134912562582
   PubMed Web of Science ®Google Scholar
• CummingsJLBackCThe cholinergic hypothesis of neuropsychiatric symptoms in Alzheimer’s diseaseAm J Geriatr Psychiatry199862 Suppl 1S64S789581223
   PubMed Web of Science ®Google Scholar
• ZubenkoGSMoossyJMartinezAJNeuropathologic and neurochemical correlates of psychosis in primary dementiaArch Neurol19914866196241710105
   PubMedGoogle Scholar
• SweetRAHamiltonRLHealyMTAlterations of striatal dopamine receptor binding in Alzheimer disease are associated with Lewy body pathology and antemortem psychosisArch Neurol200158346647211255451
   PubMedGoogle Scholar
• ReevesSBrownRHowardRGrasbyPIncreased striatal dopamine (D2/D3) receptor availability and delusions in Alzheimer diseaseNeurology200972652853419204262
   PubMed Web of Science ®Google Scholar
• VermeirenYVan DamDAertsTEngelborghsSDe DeynPPBrain region-specific monoaminergic correlates of neuropsychiatric symptoms in Alzheimer’s diseaseJ Alzheimers Dis201441381983324685637
   PubMed Web of Science ®Google Scholar
• Garcia-AllozaMGil-BeaFJDiez-ArizaMCholinergic-serotonergic imbalance contributes to cognitive and behavioral symptoms in Alzheimer’s diseaseNeuropsychologia200543344244915707619
   PubMed Web of Science ®Google Scholar
• MarcosBGarcía-AllozaMGil-BeaFJInvolvement of an altered 5-HT-{6} receptor function in behavioral symptoms of Alzheimer’s diseaseJ Alzheimers Dis2008141435018525126
   PubMed Web of Science ®Google Scholar
• FörstlHBurnsALevyRCairnsNNeuropathological correlates of psychotic phenomena in confirmed Alzheimer’s diseaseBr J Psychiatry1994165153597953058
   PubMed Web of Science ®Google Scholar
• ArriagadaPVGrowdonJHHedley-WhyteETHymanBTNeurofibrillary tangles but not senile plaques parallel duration and severity of Alzheimer’s diseaseNeurology1992423 Pt 16316391549228
   PubMed Web of Science ®Google Scholar
• ZubenkoGSMolecular neurobiology of Alzheimer’s disease (syndrome?)Harv Rev Psychiatry1997541772139427013
   PubMed Web of Science ®Google Scholar
• FarberNBRubinEHNewcomerJWIncreased neocortical neurofibrillary tangle density in subjects with Alzheimer disease and psychosisArch Gen Psychiatry200057121165117311115331
   PubMed Web of Science ®Google Scholar
• ClarkCMXieSChittamsJCerebrospinal fluid tau and beta-amyloid: how well do these biomarkers reflect autopsy-confirmed dementia diagnoses?Arch Neurol200360121696170214676043
   PubMedGoogle Scholar
• TapiolaTOvermyerMLehtovirtaMThe level of cerebrospinal fluid tau correlates with neurofibrillary tangles in Alzheimer’s diseaseNeuroreport1997818396139639462474
   PubMed Web of Science ®Google Scholar
• KoppelJSundaySButhornJGoldbergTDaviesPGreenwaldBAlzheimer’s Disease Neuroimaging InitiativeElevated CSF Tau is associated with psychosis in Alzheimer’s diseaseAm J Psychiatry2013170101212121324084821
   PubMed Web of Science ®Google Scholar
• CrowtherRAOlesenOFJakesRGoedertMThe microtubule binding repeats of tau protein assemble into filaments like those found in Alzheimer’s diseaseFEBS Lett199230921992021505683
   PubMed Web of Science ®Google Scholar
• MurrayPSKirkwoodCMGrayMCHyperphosphorylated tau is elevated in Alzheimer’s disease with psychosisJ Alzheimers Dis201439475977324270207
   PubMed Web of Science ®Google Scholar
• AckerCMForestSKZinkowskiRDaviesPd’AbramoCSensitive quantitative assays for tau and phospho-tau in transgenic mouse modelsNeurobiol Aging201334133835022727277
   PubMed Web of Science ®Google Scholar
• AugustinackJCSchneiderAMandelkowEMHymanBTSpecific tau phosphorylation sites correlate with severity of neuronal cytopathology in Alzheimer’s diseaseActa Neuropathol20021031263511837744
   PubMed Web of Science ®Google Scholar
• McKeithIGDicksonDWLoweJet al; Consortium onDLBDiagnosis and management of dementia with Lewy bodies: third report of the DLB ConsortiumNeurology200565121863187216237129
   PubMed Web of Science ®Google Scholar
• KoppelJAckerCDaviesPPsychotic Alzheimer’s disease is associated with gender-specific tau phosphorylation abnormalitiesNeurobiol Aging20143592021202824731519
   PubMed Web of Science ®Google Scholar
• RockwellEKrullAJDimsdaleJJesteDVLate-onset psychosis with somatic delusionsPsychosomatics199435166728134531
   PubMed Web of Science ®Google Scholar
• LeroiIVoulgariABreitnerJCLyketsosCGThe epidemiology of psychosis in dementiaAm J Geriatr Psychiatry2003111839112527543
   PubMed Web of Science ®Google Scholar
• MoranEKBeckerJASatlinALyooIKFischmanAJJohnsonKAPsychosis of Alzheimer’s disease: Gender differences in regional perfusionNeurobiol Aging20082981218122517408808
   PubMed Web of Science ®Google Scholar
• LaFerlaFMGreenKNAnimal models of Alzheimer diseaseCold Spring Harb Perspect Med2012211
   Web of Science ®Google Scholar
• van den BuuseMModeling the positive symptoms of schizophrenia in genetically modified mice: pharmacology and methodology aspectsSchizophr Bull201036224627019900963
   PubMed Web of Science ®Google Scholar
• LaruelleMAbi-DarghamAGilRKegelesLInnisRIncreased dopamine transmission in schizophrenia: relationship to illness phasesBiol Psychiatry1999461567210394474
   PubMed Web of Science ®Google Scholar
• BraffDStoneCCallawayEGeyerMGlickIBaliLPrestimulus effects on human startle reflex in normals and schizophrenicsPsychophysiology1978154339343693742
   PubMed Web of Science ®Google Scholar
• OuagazzalAMJenckFMoreauJLDrug-induced potentiation of prepulse inhibition of acoustic startle reflex in mice: a model for detecting antipsychotic activity?Psychopharmacology (Berl)20011562–327328311549229
   PubMed Web of Science ®Google Scholar
• DesbonnetLWaddingtonJLO’TuathaighCMMutant models for genes associated with schizophreniaBiochem Soc Trans200937Pt 130831219143653
   PubMed Web of Science ®Google Scholar
• SantacruzKLewisJSpiresTTau suppression in a neurodegenerative mouse model improves memory functionScience2005309573347648116020737
   PubMed Web of Science ®Google Scholar
• KoppelJJimenezHAzoseMPathogenic tau species drive a psychosis-like phenotype in a mouse model of Alzheimer’s diseaseBehav Brain Res2014275C273325151619
   PubMed Web of Science ®Google Scholar