398
Views
34
CrossRef citations to date
0
Altmetric
Review

Sleep-related hypermotor epilepsy: prevalence, impact and management strategies

, , &
Pages 317-326 | Published online: 10 Oct 2018

References

  • PedleyTAGuilleminaultCEpisodic nocturnal wanderings responsive to anticonvulsant drug therapyAnn Neurol1977213035900905
  • LugaresiECirignottaFHypnogenic paroxysmal dystonia: epileptic seizure or a new syndrome?Sleep1981421291387256073
  • LugaresiECirignottaFMontagnaPNocturnal paroxysmal dystoniaJ Neurol Neurosurg Psychiatry19864943753802939199
  • TharpBROrbital frontial seizures. An unique electroencephalographic and clinical syndromeEpilepsia19721356276424508104
  • WadaJAPurvesSJOral and bimanual-bipedal activity as ictal manifestation of frontal lobe epilepsyEpilepsia198425668
  • WadaJANocturnal recurrence of brief, intensely affective vocal and facial expression with powerful bimanual, bipedal, axial, and pelvic activity with rapid recovery as manifestations of mesial frontal lobe seizureEpilepsia198829209
  • WilliamsonPDSpencerDDSpencerSSNovellyRAMattsonRHComplex partial seizures of frontal lobe originAnn Neurol19851844975044073842
  • WatermanKPurvesSJKosakaBStraussEWadaJAAn epileptic syndrome caused by mesial frontal lobe seizure fociNeurology19873745775823104818
  • TinuperPCerulloACirignottaFCortelliPLugaresiEMontagnaPNocturnal paroxysmal dystonia with short-lasting attacks: three cases with evidence for an epileptic frontal lobe origin of seizuresEpilepsia19903155495562401246
  • OldaniAZucconiMAsseltaRAutosomal dominant nocturnal frontal lobe epilepsy. A video-polysomnographic and genetic appraisal of 40 patients and delineation of the epileptic syndromeBrain1998121Pt 22052239549500
  • ProviniFPlazziGTinuperPVandiSLugaresiEMontagnaPNocturnal frontal lobe epilepsy. A clinical and polygraphic overview of 100 consecutive casesBrain1999122Pt 61017103110356056
  • MontagnaPNocturnal paroxysmal dystonia and nocturnal wanderingNeurology1992427 Suppl 661671630641
  • NobiliLFrancioneSMaiRNocturnal frontal lobe epilepsy: intracerebral recordings of paroxysmal motor attacks with increasing complexitySleep200326788388614655924
  • TinuperPBisulliFCrossJHDefinition and diagnostic criteria of sleep-related hypermotor epilepsyNeurology201686191834184227164717
  • NobiliLFrancioneSCardinaleFLo RussoGEpileptic nocturnal wanderings with a temporal lobe origin: a stereo-electroencephalographic studySleep200225666967112224845
  • NobiliLCossuMMaiRSleep-related hyperkinetic seizures of temporal lobe originNeurology200462348248514872038
  • MaiRSartoriIFrancioneSSleep-related hyperkinetic seizures: always a frontal onset?Neurol Sci200526Suppl 3s220s22416331400
  • RyvlinPMinottiLDemarquayGNocturnal hypermotor seizures, suggesting frontal lobe epilepsy, can originate in the insulaEpilepsia200647475576516650142
  • KaidoTOtsukiTNakamaHComplex behavioral automatism arising from insular cortexEpilepsy Behav20068131531916356775
  • DobesbergerJOrtlerMUnterbergerISuccessful surgical treatment of insular epilepsy with nocturnal hypermotor seizuresEpilepsia200849115916218028409
  • ProserpioPCossuMFrancioneSEpileptic motor behaviors during sleep: anatomo-electro-clinical featuresSleep Med201112Suppl 2S33S3822136897
  • GibbsSAFigorilliMCasaceliGProserpioPNobiliLSleep Related Hypermotor Seizures with a Right Parietal OnsetJ Clin Sleep Med201511895395525902821
  • FisherRSAcevedoCArzimanoglouAA practical clinical definition of epilepsyEpilepsia20145547548224730690
  • ThomasRHKingWHJohnstonJASmithPEMAwake seizures after pure sleep-related epilepsy: a systematic review and implications for driving lawJournal of Neurology, Neurosurgery & Psychiatry2010812130135
  • DerryCPDuncanSSleep and epilepsyEpilepsy Behav201326339440423465654
  • YaqubBAWaheedGKabirajMMNocturnal epilepsies in adultsSeizure1997621451499153728
  • FernándezLBSalas-PuigJPure sleep seizures: risk of seizures while awakeEpileptic Disord200791657017307714
  • SchefferIAutosomal dominant frontal epilepsy misdiagnosed as sleep disorderThe Lancet19943438896515517
  • WeinstockAGiglioPKerrSLDuffnerPKCohenMEHyperkinetic seizures in childrenJ Child Neurol200318851752413677576
  • VignatelliLBisulliFGiovanniniGPrevalence of nocturnal frontal lobe epilepsy in the adult population of Bologna and Modena, Emilia-Romagna region, ItalySleep201538347948525406112
  • VignatelliLBisulliFGiovanniniGPrevalence of Nocturnal Frontal Lobe Epilepsy in the Adult Population of Bologna and Modena, Emilia-Romagna Region, ItalySleep201538347948525406112
  • SchefferIEBhatiaKPLopes-CendesIAutosomal dominant nocturnal frontal lobe epilepsy. A distinctive clinical disorderBrain1995118Pt 161737895015
  • NobiliLFrancioneSMaiRSurgical treatment of drug-resistant nocturnal frontal lobe epilepsyBrain2007130Pt 256157317124189
  • LicchettaLBisulliFVignatelliLSleep-related hypermotor epilepsy: Long-term outcome in a large cohortNeurology2017881707727881627
  • SchefferIEBhatiaKPLopes-CendesIAutosomal dominant frontal epilepsy misdiagnosed as sleep disorderLancet199434388965155177906762
  • SteinleinOKMulleyJCProppingPA missense mutation in the neuronal nicotinic acetylcholine receptor alpha 4 subunit is associated with autosomal dominant nocturnal frontal lobe epilepsyNat Genet19951122012037550350
  • MariniCGuerriniRThe role of the nicotinic acetylcholine receptors in sleep-related epilepsyBiochem Pharmacol20077481308131417662253
  • de FuscoMBecchettiAPatrignaniAThe nicotinic receptor beta 2 subunit is mutant in nocturnal frontal lobe epilepsyNat Genet200026327527611062464
  • CombiRFerini-StrambiLMontruccoliATwo new putative susceptibility loci for ADNFLEBrain Res Bull200567425726316182932
  • HeronSESmithKRBahloMMissense mutations in the sodium-gated potassium channel gene KCNT1 cause severe autosomal dominant nocturnal frontal lobe epilepsyNat Genet201244111188119023086396
  • IshidaSPicardFRudolfGMutations of DEPDC5 cause autosomal dominant focal epilepsiesNat Genet201345555255523542701
  • KorenkeGCEggertMThieleHNürnbergPSanderTSteinleinOKNocturnal frontal lobe epilepsy caused by a mutation in the GATOR1 complex gene NPRL3Epilepsia2016573e60e6326786403
  • RicosMGHodgsonBLPippucciTMutations in the mammalian target of rapamycin pathway regulators NPRL2 and NPRL3 cause focal epilepsyAnn Neurol201679112013126505888
  • Bar-PeledLChantranupongLCherniackADA Tumor suppressor complex with GAP activity for the Rag GTPases that signal amino acid sufficiency to mTORC1Science201334061361100110623723238
  • IfflandPHBaybisMBarnesAELeventerRJLockhartPJCrinoPBDEPDC5 and NPRL3 modulate cell size, filopodial outgrowth, and localization of mTOR in neural progenitor cells and neuronsNeurobiol Dis201811418419329481864
  • DibbensLMde VriesBDonatelloSMutations in DEPDC5 cause familial focal epilepsy with variable fociNat Genet201345554655123542697
  • SimJCScerriTFanjul-FernándezMFamilial cortical dysplasia caused by mutation in the mammalian target of rapamycin regulator NPRL3Ann Neurol201679113213726285051
  • SchefferIEHeronSEReganBMMutations in mammalian target of rapamycin regulator DEPDC5 cause focal epilepsy with brain malformationsAnn Neurol201475578278724585383
  • ChenZHWangCZhuoMQExome sequencing identified a novel missense mutation c.464G>A (p.G155D) in Ca2+-binding protein 4 (CABP4) in a Chinese pedigree with autosomal dominant nocturnal frontal lobe epilepsyOncotarget2017845789407894729108277
  • LiPFuXSmithNALoss of CLOCK Results in Dysfunction of Brain Circuits Underlying Focal EpilepsyNeuron201796238740129024662
  • PeledRLaviePParoxysmal awakenings from sleep associated with excessive daytime somnolence: a form of nocturnal epilepsyNeurology198636195983941791
  • MaccarioMLustmanLIParoxysmal nocturnal dystonia presenting as excessive daytime somnolenceArch Neurol19904732912942106869
  • OldaniAZucconiMFerini-StrambiLBizzozeroDSmirneSAutosomal dominant nocturnal frontal lobe epilepsy: electroclinical pictureEpilepsia199637109649768822695
  • OldaniAZucconiMCastronovoCFerini-StrambiLNocturnal frontal lobe epilepsy misdiagnosed as sleep apnea syndromeActa Neurol Scand199898167719696531
  • SchwalenSJörgJDay time fatigue in frontal lobe epilepsy with primarily sleep-related seizures. A case reportNervenarzt19986921661709551463
  • ZucconiMOldaniASmirneSFerini-StrambiLThe macrostructure and microstructure of sleep in patients with autosomal dominant nocturnal frontal lobe epilepsyJ Clin Neurophysiol2000171778610709813
  • Alanis-GuevaraIPeñaECoronaTLópez-AyalaTLópez-MezaELópez-GómezMSleep disturbances, socioeconomic status, and seizure control as main predictors of quality of life in epilepsyEpilepsy Behav20057348148516098815
  • VignatelliLBisulliFNaldiIExcessive daytime sleepiness and subjective sleep quality in patients with nocturnal frontal lobe epilepsy: a case-control studyEpilepsia200647Suppl 5737717239111
  • RinaldiRVignatelliLD’AlessandroRValidation of symptoms related to excessive daytime sleepinessNeuroepidemiology200120424825611684901
  • ZucconiMOldaniAFerini-StrambiLBizzozeroDSmirneSNocturnal Paroxysmal Arousals With Motor Behaviors During Sleep: Frontal Lobe Epilepsy or Parasomnia?Journal of Clinical Neurophysiology19971465135229458058
  • ParrinoLFerriRBruniOTerzanoMGCyclic alternating pattern (CAP): the marker of sleep instabilitySleep Med Rev201216274521616693
  • ParrinoLHalaszPTassinariCATerzanoMGCAP, epilepsy and motor events during sleep: the unifying role of arousalSleep Med Rev200610426728516809057
  • TerzaghiMSartoriIMaiRSleep-related minor motor events in nocturnal frontal lobe epilepsyEpilepsia200748233534117295628
  • TerzaghiMSartoriIMaiRCoupling of minor motor events and epileptiform discharges with arousal fluctuations in NFLEEpilepsia200849467067618028403
  • GibbsSAProserpioPTerzaghiMSleep-related epileptic behaviors and non-REM-related parasomnias: Insights from stereo-EEGSleep Med Rev20162542026164370
  • BisulliFVignatelliLNaldiIIncreased frequency of arousal parasomnias in families with nocturnal frontal lobe epilepsy: a common mechanism?Epilepsia20105191852186020477848
  • NobiliLNocturnal frontal lobe epilepsy and non-rapid eye movement sleep parasomnias: differences and similaritiesSleep Med Rev200711425125417628315
  • KillgoreWDEffects of sleep deprivation on cognitionProg Brain Res201018510512921075236
  • MclellanAPhillipsHARitteyCPhenotypic comparison of two Scottish families with mutations in different genes causing autosomal dominant nocturnal frontal lobe epilepsyEpilepsia200344461361712681012
  • KhatamiRNeumannMSchulzHKölmelHWA family with autosomal dominant nocturnal frontal lobe epilepsy and mental retardationJ Neurol1998245128098109840354
  • ChoYWMotamediGKLaufenbergIA Korean kindred with autosomal dominant nocturnal frontal lobe epilepsy and mental retardationArch Neurol200360111625163214623738
  • ChoYWYiSDLimJGKimDKMotamediGKAutosomal dominant nocturnal frontal lobe epilepsy and mild memory impairment associated with CHRNB2 mutation I312M in the neuronal nicotinic acetylcholine receptorEpilepsy Behav200813236136518534914
  • ItoMKobayashiKFujiiTElectroclinical picture of autosomal dominant nocturnal frontal lobe epilepsy in a Japanese familyEpilepsia2000411525810643924
  • MagnussonAStordalEBrodtkorbESteinleinOSchizophrenia, psychotic illness and other psychiatric symptoms in families with autosomal dominant nocturnal frontal lobe epilepsy caused by different mutationsPsychiatr Genet2003132919512782965
  • WoodAGSalingMMFediMNeuropsychological function in patients with a single gene mutation associated with autosomal dominant nocturnal frontal lobe epilepsyEpilepsy Behav201017453153520189461
  • HeronSESmithKRBahloMMissense mutations in the sodium-gated potassium channel gene KCNT1 cause severe autosomal dominant nocturnal frontal lobe epilepsyNat Genet201244111188119023086396
  • PicardFPegnaAJArntsbergVNeuropsychological disturbances in frontal lobe epilepsy due to mutated nicotinic receptorsEpilepsy Behav200914235435919059498
  • LicchettaLPodaR VProfile of neuropsychological impairment in Sleep-related Hypermotor EpilepsySleep Med20184881529843024
  • CentenoMThompsonPJKoeppMJHelmstaedterCDuncanJSMemory in frontal lobe epilepsyEpilepsy Res2010912–312313220800996
  • KreutzmannJCHavekesRAbelTMeerloPSleep deprivation and hippocampal vulnerability: changes in neuronal plasticity, neurogenesis and cognitive functionNeuroscience201530917319025937398
  • WirrellECEpilepsy-related injuriesEpilepsia200647Suppl 17986
  • SchenckCHMilnerDMHurwitzTDBundlieSRMahowaldMWA polysomnographic and clinical report on sleep-related injury in 100 adult patientsAm J Psychiatry19891469116611732764174
  • TassinariCATassiLCalandra-BuonauraGBiting behavior, aggression, and seizuresEpilepsia200546565466315857430
  • SiclariFKhatamiRUrbaniokFViolence in sleepBrain2010133Pt 123494350921126993
  • Delgado-EscuetaAVMattsonRHKingLSpecial report. The nature of aggression during epileptic seizuresN Engl J Med1981305127117167266614
  • LicchettaLVignatelliLBisulliFHealth-related quality of life in patients with nocturnal focal epilepsyBoll Lega It Epil2006133/134299300
  • ThomasRHKingWHJohnstonJASmithPEAwake seizures after pure sleep-related epilepsy: a systematic review and implications for driving lawJ Neurol Neurosurg Psychiatry201081213013520145025
  • BeghiESanderJWEpilepsy and drivingBMJ20053317508606116002855
  • TinuperPBisulliFFrom nocturnal frontal lobe epilepsy to Sleep-Related Hypermotor Epilepsy: A 35-year diagnostic challengeSeizure201744879228027860
  • DerryCPDaveyMJohnsMDistinguishing sleep disorders from seizures: diagnosing bumps in the nightArch of Neurol20066370570916682539
  • ManniRTerzaghiMRepettoAThe FLEP scale in diagnosing nocturnal frontal lobe epilepsy, NREM and REM parasomnias: data from a tertiary sleep and epilepsy unitEpilepsia20084991581158518410366
  • BisulliFVignatelliLNaldiIDiagnostic accuracy of a structured interview for nocturnal frontal lobe epilepsy (SINFLE): a proposal for developing diagnostic criteriaSleep Med2012131818722137114
  • LosurdoAProserpioPCardinaleFDrug-resistant focal sleep related epilepsy: results and predictors of surgical outcomeEpilepsy Res2014108595396224679947
  • HirschESellalFMatonBRumbachLMarescauxCNocturnal paroxysmal dystonia: a clinical form of focal epilepsyNeurophysiol Clin19942432072178090154
  • NobiliLProserpioPRubboliGMontanoNDidatoGTassinariCASudden unexpected death in epilepsy (SUDEP) and sleepSleep Med Rev201115423724620951616
  • MostacciBBisulliFVignatelliLIncidence of sudden unexpected death in nocturnal frontal lobe epilepsy: a cohort studySleep Med201516223223625600783
  • MostacciBBisulliFVignatelliLIncidence of sudden unexpected death in epilepsy in sleep-related hypermotor epilepsy, formerly named nocturnal frontal lobe epilepsySleep Med2017299827915205
  • LambertsRJThijsRDLaffanALanganYSanderJWSudden unexpected death in epilepsy: people with nocturnal seizures may be at highest riskEpilepsia201253225325722192074
  • ProserpioPCossuMFrancioneSInsular-opercular seizures manifesting with sleep-related paroxysmal motor behaviors: a stereo-EEG studyEpilepsia201152101781179121883183
  • RyvlinPAvoid falling into the depths of the insular trapEpileptic Disord20068Suppl 2S375617012071
  • ProviniFPlazziGLugaresiEFrom nocturnal paroxysmal dystonia to nocturnal frontal lobe epilepsyClin Neurophysiol2000111Suppl 2S2S810996549
  • PicardFBertrandSSteinleinOKBertrandDMutated nicotinic receptors responsible for autosomal dominant nocturnal frontal lobe epilepsy are more sensitive to carbamazepineEpilepsia19994091198120910487182
  • RajuGPSarcoDPPoduriARivielloJJBerginAMTakeokaMOxcarbazepine in children with nocturnal frontal-lobe epilepsyPediatr Neurol200737534534917950420
  • OldaniAManconiMZucconiMMartinelliCFerini-StrambiLTopiramate treatment for nocturnal frontal lobe epilepsySeizure200615864965216973383
  • VaradkarSDuncanJSCrossJHAcetazolamide and autosomal dominant nocturnal frontal lobe epilepsyEpilepsia200344798698712823586
  • LiguoriCRomigiAPlacidiFSarpaMGMercuriNBIzziFEffective treatment of nocturnal frontal lobe epilepsy with lacosamide: a report of two casesSleep Med20162312112226922622
  • SamarasekeraSRBerkovicSFSchefferIEA case series of lacosamide as adjunctive therapy in refractory sleep-related hypermotor epilepsy (previously nocturnal frontal lobe epilepsy)J Sleep Res2018e12669e1266929479765
  • WilloughbyJOPopeKJEatonVNicotine as an antiepileptic agent in ADNFLE: an N-of-one studyEpilepsia20034491238124012919397
  • BrodtkorbEPicardFTobacco habits modulate autosomal dominant nocturnal frontal lobe epilepsyEpilepsy Behav20069351552016931165
  • NaldiIBisulliFVignatelliLTobacco habits in nocturnal frontal lobe epilepsyEpilepsy Behav201326111411723246147
  • PulighedduMMelisMPillollaGRationale for an adjunctive therapy with fenofibrate in pharmacoresistant nocturnal frontal lobe epilepsyEpilepsia201758101762177028766701
  • de PaolisFColizziEMilioliGEffects of antiepileptic treatment on sleep and seizures in nocturnal frontal lobe epilepsySleep Med201314759760423746822
  • MikatiMAJiangYHCarboniMQuinidine in the treatment of KCNT1-positive epilepsiesAnn Neurol201578699599926369628
  • AbdelnourEGallentineWMcdonaldMSachdevMJiangYHMikatiMADoes age affect response to quinidine in patients with KCNT1 mutations? Report of three new cases and review of the literatureSeizure2018551329291456
  • NobiliLSartoriITerzaghiMRelationship of epileptic discharges to arousal instability and periodic leg movements in a case of nocturnal frontal lobe epilepsy: a stereo-EEG studySleep200629570170416774161
  • NobiliLCardinaleFMagliolaUTaylor’s focal cortical dysplasia increases the risk of sleep-related epilepsyEpilepsia200950122599260419519797
  • ManniRTerzaghiMComorbidity between epilepsy and sleep disordersEpilepsy Res201090317117720570109
  • MalowBAFoldvary-SchaeferNVaughnBVTreating obstructive sleep apnea in adults with epilepsy: a randomized pilot trialNeurology200871857257718711110