1,107
Views
35
CrossRef citations to date
0
Altmetric
Perspectives

Could long-term administration of melatonin to prepubertal children affect timing of puberty? A clinician’s perspective

, , , , , & show all
Pages 1-10 | Published online: 31 Jan 2019

References

  • AndersenLPHGögenurIRosenbergJReiterRJThe safety of melatonin in humansClin Drug Investig2016363169175
  • van GeijlswijkIMvan der HeijdenKBEgbertsACKorziliusHPSmitsMGDose finding of melatonin for chronic idiopathic childhood sleep onset insomnia: an RCTPsychopharmacology2010212337939120668840
  • CardinaliDPFurioAMReyesMPBruscoLIThe use of chronobiotics in the resynchronization of the sleep-wake cycleCancer Causes Control200617460160916596316
  • KennawayDJPotential safety issues in the use of the hormone melatonin in paediatricsJ Paediatr Child Health201551658458925643981
  • LernerABCaseJDTakahashiYLeeTHMoriWIsolation of melatonin, the pineal gland factor that lightens melanocytesJ Am Chem Soc1958
  • LernerABCaseJDTakahashiYIsolation of melatonin and 5-methoxyindole-3-acetic acid from bovine pineal glandsJ Biol Chem19602351992199714415935
  • GilletteMUTischkauSASuprachiasmatic nucleus: the brain’s circadian clockRecent Prog Horm Res1999543358 discussion 58–5910548871
  • ReiterRJPineal melatonin: cell biology of its synthesis and of its physiological interactionsEndocr Rev19911221511801649044
  • Díaz LópezBDíaz RodríguezEUrquijoCFernández ÁlvarezCMelatonin influences on the neuroendocrine-reproductive axisAnn N Y Acad Sci2005105733736416399905
  • PierpaoliWRegelsonWPineal control of aging: effect of melatonin and pineal grafting on aging miceProc Natl Acad Sci USA19949127877918290600
  • CardinaliDPPévetPBasic aspects of melatonin actionSleep Med Rev19982317519015310500
  • ReiterRJTanDXKorkmazAThe circadian melatonin rhythm and its modulation: Possible impact on hypertensionJ Hypertens Suppl2009276S17S2019633446
  • KorkmazATamuraHManchesterLCOgdenGBTanDXReiterRJCombination of melatonin and a peroxisome proliferator-activated receptor-gamma agonist induces apoptosis in a breast cancer cell lineJ Pineal Res200946111511618798787
  • CajochenCKrauchiKWirz-JusticeARole of melatonin in the regulation of human circadian rhythms and sleepJ Neuroendocrinol200315443243712622846
  • KrauchiKCajochenCWirz-JusticeAA relationship between heat loss and sleepiness: effects of postural change and melatonin administrationJ Appl Physiol19978311341399216955
  • DawsonDvan den HeuvelCJIntegrating the actions of melatonin on human physiologyAnn Med1998301951029556095
  • AttenburrowMEJCowenPJSharpleyALLow dose melatonin improves sleep in healthy middle-aged subjectsPsychopharmacology199612621791818856838
  • Wirz-JusticeAArmstrongSMMelatonin: nature’s soporific?J Sleep Res1996521371418795816
  • HastingsMHMaywoodESReddyABTwo decades of circadian timeJ Neuroendocrinol200820681281918601704
  • SimonneauxVRibelaygaCGeneration of the melatonin endocrine message in mammals: a review of the complex regulation of melatonin synthesis by norepinephrine, peptides, and other pineal transmittersPharmacol Rev200355232539512773631
  • van GeijlswijkIMKorziliusHPSmitsMGThe use of exogenous melatonin in delayed sleep phase disorder: a meta-analysisSleep201033121605161421120122
  • TosiniGFukuharaCPhotic and circadian regulation of retinal melatonin in mammalsJ Neuroendocrinol200315436436912622835
  • FourtillanJBBrissonAMGobinPIngrandIDecourtJPGiraultJBioavailability of melatonin in humans after day-time administration of D(7) melatoninBiopharm Drug Dispos2000211152211038434
  • ShamseerLVohraSComplementary, Holistic, and Integrative Medicine: Melatonin Definition and Description Available from: www.cfsan.fda.gov/Accessed November 12, 2018
  • OwensJClassification and epidemiology of childhood sleep disordersPrim Care200835353354618710669
  • SivertsenBPosserudMBGillbergCLundervoldAJHysingMSleep problems in children with autism spectrum problems: a longitudinal population-based studyAutism201216213915021478225
  • CorteseSFaraoneSVKonofalELecendreuxMSleep in children with attention-deficit/hyperactivity disorder: meta-analysis of subjective and objective studiesJ Am Acad Child Adolesc Psychiatry200948989490819625983
  • SajithSGClarkeDMelatonin and sleep disorders associated with intellectual disability: a clinical reviewJ Intellect Disabil Res200751 Pt 121317181598
  • ChaseRMPincusDBSleep-related problems in children and adolescents with anxiety disordersBehav Sleep Med20119422423622003976
  • AlfanoCAGinsburgGSKingeryJNSleep-related problems among children and adolescents with anxiety disordersJ Am Acad Child Adolesc Psychiatry200746222423217242626
  • LiuXBuysseDJGentzlerALInsomnia and hypersomnia associated with depressive phenomenology and comorbidity in childhood depressionSleep2007301839017310868
  • CarpenterJRobillardRTherapyIHVariations in the Sleep–Wake Cycle from Childhood to Adulthood: Chronobiological PerspectivesCiteseer2015 Available from: http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.838.9127&rep=rep1&type=pdfAccessed November 22, 2018
  • TonettiLAdanADi MiliaLRandlerCNataleVMeasures of circadian preference in childhood and adolescence: A reviewEur Psychiatry201530557658225726892
  • CrowleySJAceboCCarskadonMASleep, circadian rhythms, and delayed phase in adolescenceSleep Med20078660261217383934
  • ThorpyMJKormanESpielmanAJGlovinskyPBDelayed sleep phase syndrome in adolescentsJ Adolesc Heal Care1988912227
  • FalloneGOwensJADeaneJSleepiness in children and adolescents: clinical implicationsSleep Med Rev20026428730612531133
  • BrandSKirovRSleep and its importance in adolescence and in common adolescent somatic and psychiatric conditionsInt J Gen Med2011442521731894
  • SadehACognitive-behavioral treatment for childhood sleep disordersClin Psychol Rev200525561262815979219
  • HartzIHandalMTverdalASkurtveitSPaediatric off-label use of melatonin-A register linkage study between the norwegian prescription database and patient registerBasic Clin Pharmacol Toxicol2015117426727325892306
  • WaldhauserFWeiszenbacherGTatzerEAlterations in nocturnal serum melatonin levels in humans with growth and agingJ Clin Endocrinol Metab19886636486523350912
  • WaldhauserFWaldhauserMLiebermanHRDengMHLynchHJWurtmanRJBioavailability of oral melatonin in humansNeuroendocrinology19843943073136493445
  • WaldhauserFWeiszenbacherGFrischHZeitlhuberUWaldhauserMWurtmanRJFall in nocturnal serum melatonin during prepuberty and pubescenceLancet1984183743623656141425
  • CrowleySJAceboCCarskadonMAHuman puberty: salivary melatonin profiles in constant conditionsDev Psychobiol201254446847321953482
  • RoyDBelshamDDMelatonin receptor activation regulates GnRH gene expression and secretion in GT1-7 GnRH neurons. Signal transduction mechanismsJ Biol Chem2002277125125811684691
  • TerasawaEFernandezDLNeurobiological mechanisms of the onset of puberty in primatesEndocr Rev200122111115111159818
  • BelchetzPEPlantTMNakaiYKeoghEJKnobilEHypophysial responses to continuous and intermittent delivery of hypopthalamic gonadotropin-releasing hormoneScience19782024368631633100883
  • LivadasSChrousosGPControl of the onset of pubertyCurr Opin Pediatr201628455155827386974
  • WenninkJMDelemarre-van de WaalHASchoemakerRSchoemakerHSchoemakerJLuiteinizing hormone and follicle stimulatiing hormone scretion patterns in girls throughout puberty measures using highly sensitive immunoradiometric assaysClin Endocrinol1990333333344
  • ParentASTeilmannGJuulASkakkebaekNEToppariJBourguignonJPThe timing of normal puberty and the age limits of sexual precocity: variations around the world, secular trends, and changes after migrationEndocr Rev200324566869314570750
  • LiuXHerbisonAEKisspeptin regulation of neuronal activity throughout the central nervous systemEndocrinol Metab2016312193205
  • LeeJHMieleMEHicksDJKiSS-1, a novel human malignant melanoma metastasis-suppressor geneJ Natl Cancer Inst19968823173117378944003
  • HanSKGottschMLLeeKJActivation of gonadotropin-releasing hormone neurons by kisspeptin as a neuroendocrine switch for the onset of pubertyJ Neurosci20052549113491135616339030
  • KirilovMClarksonJLiuXDependence of fertility on kisspeptin-Gpr54 signaling at the GnRH neuronNat Commun201341249224051579
  • NovairaHJSonkoMLHoffmanGDisrupted kisspeptin signaling in GnRH neurons leads to hypogonadotrophic hypogonadismMol Endocrinol201428222523824422632
  • LeónSBarrosoAVázquezMJDirect Actions of Kisspeptins on GnRH Neurons Permit Attainment of Fertility but are Insufficient to Fully Preserve Gonadotropic Axis ActivitySci Rep201661920626755241
  • MessagerSChatzidakiEEMaDKisspeptin directly stimulates gonadotropin-releasing hormone release via G protein-coupled receptor 54Proc Natl Acad Sci USA200510251761176615665093
  • IrwigMSFraleyGSSmithJTKisspeptin activation of gonadotropin releasing hormone neurons and regulation of KiSS-1 mRNA in the male ratNeuroendocrinology200480426427215665556
  • SimonneauxVAnselLRevelFGKlosenPPévetPMikkelsenJDKisspeptin and the seasonal control of reproduction in hamstersPeptides200930114615318619505
  • RevelFGSaboureauMMasson-PévetMPévetPMikkelsenJDSimonneauxVKisspeptin mediates the photoperiodic control of reproduction in hamstersCurr Biol200616171730173516950111
  • GingerichSWangXLeePKThe generation of an array of clonal, immortalized cell models from the rat hypothalamus: analysis of melatonin effects on kisspeptin and gonadotropin-inhibitory hormone neuronsNeuroscience200916241134114019463905
  • LarkinJEJonesJZuckerITemperature dependence of gonadal regression in Syrian hamsters exposed to short day lengthsAm J Physiol Regul Integr Comp Physiol20022823R744R75211832395
  • LehmanMNCoolenLMGoodmanRLViguieCBillingsHJKarschFJSeasonal plasticity in the brain: the use of large animal models for neuroanatomical researchReprod Suppl20025914916512698979
  • PaulMJZuckerISchwartzWJTracking the seasons: the internal calendars of vertebratesPhilos Trans R Soc B Biol Sci20083631490341361
  • GoodmanRLJansenHTBillingsHJCoolenLMLehmanMNNeural systems mediating seasonal breeding in the eweJ Neuroendocrinol201022767468120456601
  • FosterDLPuberty in the female sheepKnobilENeillJDPhysiology of ReproductionRaven Press1988New York
  • FosterDLKarschFJDevelopment of the mechanism regulating the preovulatory surge of luteinizing hormone in sheepEndocrinology1975975120512091183409
  • TranCTEdeyTNFindlayJKPituitary response of prepuberal lambs to oestradiol-17 betaAust J Biol Sci1979324–5463120739
  • ClarkeIJGonadotrophin-releasing hormone secretion (GnRH) in anoestrous ewes and the induction of GnRH surges by oestrogenJ Endocrinol198811733553603292694
  • FosterDLLemonsJAJaffeRBNiswenderGDSequential patterns of circulating luteinizing hormone and follicle-stimulating hormone in female sheep from early postnatal life through the first estrous cyclesEndocrinology19759749859941238249
  • YellonSMGoldmanBDPhotoperiod control of reproductive development in the male Djungarian hamster (Phodopus sungorus)Endocrinology198411426646706418534
  • BuchananKLYellonSMDelayed puberty in the male Djungarian hamster: effect of short photoperiod or melatonin treatment on the GnRH neuronal systemNeuroendocrinology1991542961021766555
  • KennawayDJHughesPEvan WettereWHMelatonin implants do not alter estrogen feedback or advance puberty in giltsAnim Reprod Sci2015156132225618532
  • KennawayDJPeekJCGilmoreTARoylesPPituitary response to LHRH, LH pulsatility and plasma melatonin and prolactin changes in ewe lambs treated with melatonin implants to delay pubertyJ Reprod Fertil19867811371483531504
  • RecabarrenSELobosAHenriquezJPeneipilCPariloJEffect of daily melatonin treatment on the profile of luteinizing hormone secretion in prepubertal ewesAgrociencia19981430315
  • KennawayDJGilmoreTADunstanEAPinealectomy delays puberty in ewe lambsJ Reprod Fertil19857411191254040570
  • WagnerGCJohnstonJDClarkeIJLincolnGAHazleriggDGRedefining the limits of day length responsiveness in a seasonal mammalEndocrinology20081491323917901234
  • YellonSMFosterDLMelatonin rhythms time photoperiod-induced puberty in the female lambEndocrinology1986119144493720672
  • SimonneauxVAncelCPoirelVJGauerFKisspeptins and RFRP-3 act in concert to synchronize rodent reproduction with seasonsFront Neurosci201372223550229
  • MalpauxBMigaudMTricoireHChemineauPBiology of mammalian photoperiodism and the critical role of the pineal gland and melatoninJ Biol Rhythms200116433634711506379
  • GoldmanBDMammalian photoperiodic system: formal properties and neuroendocrine mechanisms of photoperiodic time measurementJ Biol Rhythms200116428330111506375
  • van GeijlswijkIMMolRHEgbertsTCSmitsMGEvaluation of sleep, puberty and mental health in children with long-term melatonin treatment for chronic idiopathic childhood sleep onset insomniaPsychopharmacology2011216111112021340475
  • ZwartTSmitsMEgbertsTRademakerCvan GeijlswijkILong-Term Melatonin Therapy for Adolescents and Young Adults with Chronic Sleep Onset Insomnia and Late Melatonin Onset: Evaluation of Sleep Quality, Chronotype, and Lifestyle Factors Compared to Age-Related Randomly Selected Population CohortsHealthcare2018612328711504
  • CarrRWasdellMBHamiltonDLong-term effectiveness outcome of melatonin therapy in children with treatment-resistant circadian rhythm sleep disordersJ Pineal Res200743435135917910603
  • MageeKBasinskaJQuarringtonBStancerHCBlindness and menarcheLife Sci1970917125435855
  • BojlénKBentzonMWSeasonal variation in the occurrence of menarcheDan Med Bull19742151611684605089
  • AlbrightDLVodaAMSmolenskyMHHsiBPDeckerMSeasonal characteristics of and age at menarcheChronobiol Int1990732512582268887
  • CohenPMonth at menarche: a re-evaluation of the seasonal hypothesisAnn Hum Biol19932021982028447664
  • RojanskyNBrzezinskiASchenkerJGSeasonality in human reproduction: an updateHum Reprod1992767357451323571
  • SilmanRELeoneRMHooperRJPreeceMAMelatonin, the pineal gland and human pubertyNature19792825736301303503201
  • SaltiRGalluzziFBindiGNocturnal melatonin patterns in childrenJ Clin Endocrinol Metab20008562137214410852442
  • CavalloARitschelWAPharmacokinetics of melatonin in human sexual maturationJ Clin Endocrinol Metab1996815188218868626852
  • MarceauKRamNHoutsRMGrimmKJSusmanEJIndividual differences in boys’ and girls’ timing and tempo of puberty: modeling development with nonlinear growth modelsDev Psychol20114751389140921639623
  • TaylorDJRoaneBMTreatment of insomnia in adults and children: a practice-friendly review of researchJ Clin Psychol201066111137114720890946
  • KalakNGerberMKirovRDaily morning running for 3 weeks improved sleep and psychological functioning in healthy adolescents compared with controlsJ Adolesc Health201251661562223174473
  • CreswellJDIrwinMRBurklundLJMindfulness-Based Stress Reduction training reduces loneliness and pro-inflammatory gene expression in older adults: a small randomized controlled trialBrain Behav Immun20122671095110122820409
  • MorinCMBootzinRRBuysseDJEdingerJDEspieCALichsteinKLPsychological and behavioral treatment of insomnia:update of the recent evidence (1998–2004)Sleep200629111398141417162986
  • KennawayDJLight, neurotransmitters and the suprachiasmatic nucleus control of pineal melatonin production in the ratNeurosignals199764–6247254