High Rapid Eye Movement Sleep Apnea Hypopnea Index is Associated with Hypertension in Patients with Obstructive Sleep Apnea

References

• Benjafield AV, Ayas NT, Eastwood PR, et al. Estimation of the global prevalence and burden of obstructive sleep apnoea: a literature-based analysis. Lancet Respir Med. 2019;7(8):687–698. doi:10.1016/s2213-2600(19)30198-5
   PubMed Web of Science ®Google Scholar
• Mashaqi S, Gozal D. Obstructive sleep apnea and systemic hypertension: gut dysbiosis as the mediator? J Clin Sleep Med. 2019;15(10):1517–1527. doi:10.5664/jcsm.7990
   PubMed Web of Science ®Google Scholar
• Peppard PE, Young T, Palta M, Skatrud J. Prospective study of the association between sleep-disordered breathing and hypertension. N Engl J Med. 2000;342(19):1378–1384. doi:10.1056/nejm200005113421901
   PubMed Web of Science ®Google Scholar
• Muxfeldt ES, Margallo V, Costa LM, et al. Effects of continuous positive airway pressure treatment on clinic and ambulatory blood pressures in patients with obstructive sleep apnea and resistant hypertension: a randomized controlled trial. Hypertension. 2015;65(4):736–742. doi:10.1161/hypertensionaha.114.04852
   PubMed Web of Science ®Google Scholar
• Thunström E, Manhem K, Rosengren A, Peker Y. Blood pressure response to losartan and continuous positive airway pressure in hypertension and obstructive sleep apnea. Am J Respir Crit Care Med. 2016;193(3):310–320. doi:10.1164/rccm.201505-0998OC
   PubMed Web of Science ®Google Scholar
• Hou H, Zhao Y, Yu W, et al. Association of obstructive sleep apnea with hypertension: a systematic review and meta-analysis. J Glob Health. 2018;8(1):010405. doi:10.7189/jogh.08.010405
   PubMed Web of Science ®Google Scholar
• Kohler M, Stradling JR. CrossTalk proposal: most of the cardiovascular consequences of OSA are due to increased sympathetic activity. J Physiol. 2012;590(12):2813–2815;discussion 2823. doi:10.1113/jphysiol.2012.229633
   PubMed Web of Science ®Google Scholar
• Pirzada AR, BaHammam AS. Rapid eye movement predominant obstructive sleep apnoea: prognostic relevance and clinical approach. Curr Opin Pulm Med. 2021;27(6):514–522. doi:10.1097/mcp.0000000000000817
   PubMed Web of Science ®Google Scholar
• Mokhlesi B, Finn LA, Hagen EW, et al. Obstructive sleep apnea during REM sleep and hypertension. results of the Wisconsin Sleep Cohort. Am J Respir Crit Care Med. 2014;190(10):1158–1167. doi:10.1164/rccm.201406-1136OC
   PubMed Web of Science ®Google Scholar
• Mokhlesi B, Hagen EW, Finn LA, Hla KM, Carter JR, Peppard PE. Obstructive sleep apnoea during REM sleep and incident non-dipping of nocturnal blood pressure: a longitudinal analysis of the Wisconsin Sleep Cohort. Thorax. 2015;70(11):1062–1069. doi:10.1136/thoraxjnl-2015-207231
   PubMed Web of Science ®Google Scholar
• Appleton SL, Vakulin A, Martin SA, et al. Hypertension is associated with undiagnosed OSA during rapid eye movement sleep. Chest. 2016;150(3):495–505. doi:10.1016/j.chest.2016.03.010
   PubMed Web of Science ®Google Scholar
• Rishi AR, Rishi MA. Rapid eye movement related obstructive sleep apnea: where do we stand? Respir Investig. 2021;59(5):589–595. doi:10.1016/j.resinv.2021.06.006
   PubMed Web of Science ®Google Scholar
• Basoglu OK, Tasbakan MS. Gender differences in clinical and polysomnographic features of obstructive sleep apnea: a clinical study of 2827 patients. Sleep Breath. 2018;22(1):241–249. doi:10.1007/s11325-017-1482-9
   PubMed Web of Science ®Google Scholar
• Koo BB, Dostal J, Ioachimescu O, Budur K. The effects of gender and age on REM-related sleep-disordered breathing. Sleep Breath. 2008;12(3):259–264. doi:10.1007/s11325-007-0161-7
   PubMed Web of Science ®Google Scholar
• Krakauer NY, Krakauer JC. A new body shape index predicts mortality hazard independently of body mass index. PLoS One. 2012;7(7):e39504. doi:10.1371/journal.pone.0039504
   PubMed Web of Science ®Google Scholar
• Berry RB, Budhiraja R, Gottlieb DJ, et al. Rules for scoring respiratory events in sleep: update of the 2007 AASM manual for the scoring of sleep and associated events. Deliberations of the sleep apnea definitions task force of the American Academy of sleep medicine. J Clin Sleep Med. 2012;8(5):597–619. doi:10.5664/jcsm.2172
   PubMed Web of Science ®Google Scholar
• Guide TJCoCHP. Guidelines on Prevention and Treatment of Hypertension in China (2018 edition). Chin J Cardiovasc. 2019;24(1):24–56.
   Google Scholar
• Olack B, Wabwire-Mangen F, Smeeth L, Montgomery JM, Kiwanuka N, Breiman RF. Risk factors of hypertension among adults aged 35-64 years living in an urban slum Nairobi, Kenya. BMC Public Health. 2015;15:1251. doi:10.1186/s12889-015-2610-8
   PubMed Web of Science ®Google Scholar
• Aserinsky E, Kleitman N. Regularly occurring periods of eye motility, and concomitant phenomena, during sleep. Science. 1953;118(3062):273–274. doi:10.1126/science.118.3062.273
   PubMed Web of Science ®Google Scholar
• Alzoubaidi M, Mokhlesi B. Obstructive sleep apnea during rapid eye movement sleep: clinical relevance and therapeutic implications. Curr Opin Pulm Med. 2016;22(6):545–554. doi:10.1097/mcp.0000000000000319
   PubMed Web of Science ®Google Scholar
• Mokhlesi B, Punjabi NM. “REM-related” obstructive sleep apnea: an epiphenomenon or a clinically important entity? Sleep. 2012;35(1):5–7. doi:10.5665/sleep.1570
   PubMed Web of Science ®Google Scholar
• Somers VK, Dyken ME, Clary MP, Abboud FM. Sympathetic neural mechanisms in obstructive sleep apnea. J Clin Invest. 1995;96(4):1897–1904. doi:10.1172/jci118235
   PubMed Web of Science ®Google Scholar
• Mokhlesi B, Carter JR. Growing evidence linking OSA during rapid eye movement sleep to systemic hypertension. Chest. 2016;150(3):475–477. doi:10.1016/j.chest.2016.03.047
   PubMed Web of Science ®Google Scholar
• Peppard PE, Ward NR, Morrell MJ. The impact of obesity on oxygen desaturation during sleep-disordered breathing. Am J Respir Crit Care Med. 2009;180(8):788–793. doi:10.1164/rccm.200905-0773OC
   PubMed Web of Science ®Google Scholar
• Sawyer AM, Gooneratne NS, Marcus CL, Ofer D, Richards KC, Weaver TE. A systematic review of CPAP adherence across age groups: clinical and empiric insights for developing CPAP adherence interventions. Sleep Med Rev. 2011;15(6):343–356. doi:10.1016/j.smrv.2011.01.003
   PubMed Web of Science ®Google Scholar
• Grimaldi D, Beccuti G, Touma C, Van Cauter E, Mokhlesi B. Association of obstructive sleep apnea in rapid eye movement sleep with reduced glycemic control in type 2 diabetes: therapeutic implications. Diabetes Care. 2014;37(2):355–363. doi:10.2337/dc13-0933
   PubMed Web of Science ®Google Scholar
• Martínez-García MA, Capote F, Campos-Rodríguez F, et al. Effect of CPAP on blood pressure in patients with obstructive sleep apnea and resistant hypertension: the HIPARCO randomized clinical trial. JAMA. 2013;310(22):2407–2415. doi:10.1001/jama.2013.281250
   PubMed Web of Science ®Google Scholar
• Haentjens P, Van Meerhaeghe A, Moscariello A, et al. The impact of continuous positive airway pressure on blood pressure in patients with obstructive sleep apnea syndrome: evidence from a meta-analysis of placebo-controlled randomized trials. Arch Intern Med. 2007;167(8):757–764. doi:10.1001/archinte.167.8.757
   PubMedGoogle Scholar
• Barbé F, Durán-Cantolla J, Sánchez-de-la-Torre M, et al. Effect of continuous positive airway pressure on the incidence of hypertension and cardiovascular events in nonsleepy patients with obstructive sleep apnea: a randomized controlled trial. JAMA. 2012;307(20):2161–2168. doi:10.1001/jama.2012.4366
   PubMed Web of Science ®Google Scholar