Influence of Age and Sex on Disease Course and Treatment in Rheumatoid Arthritis

References

• Eriksson JK, Neovius M, Ernestam S, Lindblad S, Simard JF, Askling J. Incidence of rheumatoid arthritis in Sweden: a nationwide population-based assessment of incidence, its determinants, and treatment penetration. Arthritis Care Res (Hoboken). 2013;65(6):870–878. doi:10.1002/acr.21900
   PubMed Web of Science ®Google Scholar
• Tengstrand B, Ahlmen M, Hafstrom I. The influence of sex on rheumatoid arthritis: a prospective study of onset and outcome after 2 years. J Rheumatol. 2004;31(2):214–222.
   PubMed Web of Science ®Google Scholar
• Sokka T, Toloza S, Cutolo M, et al. Women, men, and rheumatoid arthritis: analyses of disease activity, disease characteristics, and treatments in the QUEST-RA study. Arthritis Res Ther. 2009;11(1):R7. doi:10.1186/ar2591
   PubMed Web of Science ®Google Scholar
• van Onna M, Boonen A. The challenging interplay between rheumatoid arthritis, ageing and comorbidities. BMC Musculoskelet Disord. 2016;17(1):184. doi:10.1186/s12891-016-1038-3
   Web of Science ®Google Scholar
• Eriksson JK, Johansson K, Askling J, Neovius M. Costs for hospital care, drugs and lost work days in incident and prevalent rheumatoid arthritis: how large, and how are they distributed? Ann Rheum Dis. 2015;74(4):648–654. doi:10.1136/annrheumdis-2013-204080
   Web of Science ®Google Scholar
• Singh JA, Saag KG, Bridges SL Jr., et al. 2015 American college of rheumatology guideline for the treatment of rheumatoid arthritis. Arthritis Rheumatol. 2016;68(1):1–26. doi:10.1002/art.39480
   PubMed Web of Science ®Google Scholar
• Smolen JS, Landewe RBM, Bijlsma JWJ, et al. EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2019 update. Ann Rheum Dis. 2020;79(6):685–699. doi:10.1136/annrheumdis-2019-216655
   PubMed Web of Science ®Google Scholar
• van Hulst LT, Kievit W, van Bommel R, van Riel PL, Fraenkel L. Rheumatoid arthritis patients and rheumatologists approach the decision to escalate care differently: results of a maximum difference scaling experiment. Arthritis Care Res (Hoboken). 2011;63(10):1407–1414. doi:10.1002/acr.20551
   PubMed Web of Science ®Google Scholar
• Ogasawara M, Tamura N, Onuma S, et al. Observational cross-sectional study revealing less aggressive treatment in Japanese elderly than nonelderly patients with rheumatoid arthritis. J Clin Rheumatol. 2010;16(8):370–374. doi:10.1097/RHU.0b013e3181fe8b37
   Web of Science ®Google Scholar
• Tutuncu Z, Reed G, Kremer J, Kavanaugh A. Do patients with older-onset rheumatoid arthritis receive less aggressive treatment? Ann Rheum Dis. 2006;65(9):1226–1229. doi:10.1136/ard.2005.051144
   PubMed Web of Science ®Google Scholar
• Oishi S, Wendling D, Sibilia J, et al. Treatment of active rheumatoid arthritis: comparison of patients younger vs older than 75 years (CORPUS cohort). Hum Vaccin Immunother. 2018;14(11):2612–2617. doi:10.1080/21645515.2018.1522470
   PubMed Web of Science ®Google Scholar
• Innala L, Berglin E, Moller B, et al. Age at onset determines severity and choice of treatment in early rheumatoid arthritis: a prospective study. Arthritis Res Ther. 2014;16(2):R94. doi:10.1186/ar4540
   Web of Science ®Google Scholar
• Arnold MB, Bykerk VP, Boire G, et al. Are there differences between young- and older-onset early inflammatory arthritis and do these impact outcomes? An analysis from the CATCH cohort. Rheumatology (Oxford). 2014;53(6):1075–1086. doi:10.1093/rheumatology/ket449
   PubMed Web of Science ®Google Scholar
• Steffen A, Holstiege J, Klimke K, Akmatov MK, Batzing J. Patterns of the initiation of disease-modifying antirheumatic drugs in incident rheumatoid arthritis: a German perspective based on nationwide ambulatory drug prescription data. Rheumatol Int. 2018;38(11):2111–2120. doi:10.1007/s00296-018-4161-7
   Web of Science ®Google Scholar
• Hafstrom I, Ajeganova S, Andersson ML, et al. A Swedish register-based, long-term inception cohort study of patients with rheumatoid arthritis - results of clinical relevance. Open Access Rheumatol. 2019;11:207–217. doi:10.2147/OARRR.S218448
   PubMed Web of Science ®Google Scholar
• Arnett FC, Edworthy SM, Bloch DA, et al. The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum. 1988;31(3):315–324. doi:10.1002/art.1780310302
   PubMed Web of Science ®Google Scholar
• Prevoo ML, van ‘T Hof MA, Kuper HH, van Leeuwen MA, van de Putte LB, van Riel PL. Modified disease activity scores that include twenty-eight-joint counts. Development and validation in a prospective longitudinal study of patients with rheumatoid arthritis. Arthritis Rheum. 1995;38(1):44–48. doi:10.1002/art.1780380107
   PubMed Web of Science ®Google Scholar
• Ekdahl C, Eberhardt K, Andersson SI, Svensson B. Assessing disability in patients with rheumatoid arthritis. Use of a Swedish version of the stanford health assessment questionnaire. Scand J Rheumatol. 1988;17(4):263–271. doi:10.3109/03009748809098795
   PubMed Web of Science ®Google Scholar
• van der Heijde D. How to read radiographs according to the Sharp/van der Heijde method. J Rheumatol. 2000;27(1):261–263.
   PubMed Web of Science ®Google Scholar
• Armstrong RA. When to use the Bonferroni correction. Ophthalmic Physiol Opt. 2014;34(5):502–508. doi:10.1111/opo.12131
   PubMed Web of Science ®Google Scholar
• Miller A, Green M, Robinson D. Simple rule for calculating normal erythrocyte sedimentation rate. Br Med J (Clin Res Ed). 1983;286(6361):266. doi:10.1136/bmj.286.6361.266
   PubMed Web of Science ®Google Scholar
• Camacho EM, Verstappen SM, Lunt M, Bunn DK, Symmons DP. Influence of age and sex on functional outcome over time in a cohort of patients with recent-onset inflammatory polyarthritis: results from the Norfolk Arthritis Register. Arthritis Care Res (Hoboken). 2011;63(12):1745–1752. doi:10.1002/acr.20609
   Web of Science ®Google Scholar
• Andersson ML, Forslind K, Hafstrom I. Comparing five year out-come in two cohorts of patients with early rheumatoid arthritis - A BARFOT Study. Open Rheumatol J. 2015;9(1):8–15. doi:10.2174/1874312901409010008
   Google Scholar
• Khanna D, Ranganath VK, Fitzgerald J, et al. Increased radiographic damage scores at the onset of seropositive rheumatoid arthritis in older patients are associated with osteoarthritis of the hands, but not with more rapid progression of damage. Arthritis Rheum. 2005;52(8):2284–2292. doi:10.1002/art.21221
   Web of Science ®Google Scholar
• Ahlmen M, Svensson B, Albertsson K, Forslind K, Hafstrom I. Influence of gender on assessments of disease activity and function in early rheumatoid arthritis in relation to radiographic joint damage. Ann Rheum Dis. 2010;69(1):230–233. doi:10.1136/ard.2008.102244
   PubMed Web of Science ®Google Scholar
• Favalli EG, Biggioggero M, Crotti C, Becciolini A, Raimondo MG, Meroni PL. Sex and management of rheumatoid arthritis. Clin Rev Allergy Immunol. 2019;56(3):333–345. doi:10.1007/s12016-018-8672-5
   PubMed Web of Science ®Google Scholar
• Serhal L, Lwin MN, Holroyd C, Edwards CJ. Rheumatoid arthritis in the elderly: characteristics and treatment considerations. Autoimmun Rev. 2020;19(6):102528. doi:10.1016/j.autrev.2020.102528
   PubMed Web of Science ®Google Scholar
• Frisell T, Baecklund E, Bengtsson K, et al. Patient characteristics influence the choice of biological drug in RA, and will make non-TNFi biologics appear more harmful than TNFi biologics. Ann Rheum Dis. 2018;77(5):650–657. doi:10.1136/annrheumdis-2017-212395
   PubMed Web of Science ®Google Scholar
• Kobak S, Bes C. An autumn tale: geriatric rheumatoid arthritis. Ther Adv Musculoskelet Dis. 2018;10(1):3–11. doi:10.1177/1759720X17740075
   PubMed Web of Science ®Google Scholar
• Andersson MLE, Forslind K, Hafstrom I. Patients with early rheumatoid arthritis in the 2000s have equal disability and pain despite less disease activity compared with the 1990s: data from the BARFOT Study over 8 years. J Rheumatol. 2017;44(6):723–731. doi:10.3899/jrheum.161235
   Web of Science ®Google Scholar