References
- MathersCDLoncarDProjections of global mortality and burden of disease from 2002 to 2030PLoS Med2006311e44217132052
- Centers for Disease Control and Prevention National Diabetes Statistics Reports2017 Available from: https://www.cdc.gov/diabetes/pdfs/data/statistics/national-diabetes-statistics-report.pdfAccessed November 21, 2017
- BoultonAJVinikAIArezzoJCAmerican Diabetes AssociationDiabetic neuropathies: a statement by the American Diabetes AssociationDiabetes Care200528495696215793206
- OshitariTDezawaMOkadaSThe role of c-fos in cell death and regeneration of retinal ganglion cellsInvest Ophthalmol Vis Sci20024372442244912091449
- OshitariTBikbovaGYamamotoSIncreased expression of phosphorylated c-Jun and phosphorylated c-Jun N-terminal kinase associated with neuronal cell death in diabetic and high glucose exposed rat retinasBrain Res Bull2014101182524333191
- BikbovaGOshitariTBabaTYamamotoSAltered expression of NF-κ B and SP1 after exposure to advanced glycation end-products and effects of neurotrophic factors in AGEs exposed rat retinasJ Diabetes Res2015201554381826078979
- BikbovaGOshitariTBabaTYamamotoSMechanisms of neuronal cell death in AGE-exposed retinas – research and literature reviewCurr Diabetes Rev201713328028827193899
- LeongYYTongLBarrier function in the ocular surface: from conventional paradigms to new opportunitiesOcul Surf201513210310925881994
- MüllerLJMarfurtCFKruseFTervoTMCorneal nerves: structure, contents and functionExp Eye Res200376552154212697417
- ShaheenBSBakirMJainSCorneal nerves in health and diseaseSurv Ophthalmol201459326328524461367
- HeJBazanHEMapping the nerve architecture of diabetic human corneasOphthalmology2012119595696422325488
- KimJKimCSSohnEJeongIHKimHKimJSInvolvement of advanced glycation end products, oxidative stress and nuclear factor-kappaB in the development of diabetic keratopathyGraefes Arch Clin Exp Ophthalmol2011249452953621104267
- The definition and classification of dry eye disease: report of the Definition and Classification Subcommittee of the International Dry Eye WorkShop (2007)Ocul Surf200752759217508116
- ZhangXZhaoLDengSSunXWangNDry eye syndrome in patients with diabetes mellitus: prevalence, etiology, and clinical characteristicsJ Ophthalmol20162016820105327213053
- KesarwaniDRizviSWAKhanAAAmitavaAKVasenwalaSMSiddiquiZTear film and ocular surface dysfunction in diabetes mellitus in an Indian populationIndian J Ophthalmol201765430130428513494
- HollandEJMannisMJLeeWBOcular Surface Disease: Cornea, Conjunctiva and Tear FilmLondonElsevier/Saunders2013
- ToygarOSizmazSPelitAToygarBYabaş KiziloğluÖAkovaYCentral corneal thickness in type II diabetes mellitus: is it related to the severity of diabetic retinopathy?Turkish J Med Sci2015453651654
- OzdamarYCankayaBOzalpSAcarogluGKarakayaJOzkanSSIs there a correlation between diabetes mellitus and central corneal thickness?J Glaucoma201019961361620051882
- NishitsukaKKawasakiRKannoMFunagata StudyDeterminants and risk factors for central corneal thickness in Japanese persons: the Funagata StudyOphthalmic Epidemiol201118524424921961514
- ZouCWangSHuangFZhangYAAdvanced glycation end products and ultrastructural changes in corneas of long-term streptozotocin-induced diabetic monkeysCornea201231121455145922695699
- MocanMCIrkeçMOrhanMEvidence of Waite–Beetham lines in the corneas of diabetic patients as detected by in vivo confocal microscopyEye (Lond)200620121488149016645622
- LeemHSLeeKJShinKCCentral corneal thickness and corneal endothelial cell changes caused by contact lens use in diabetic patientsYonsei Med J201152232232521319353
- UrbanBRaczyńskaDBakunowicz-ŁazarczykARaczyńskaKKrętowskaMEvaluation of corneal endothelium in children and adolescents with type 1 diabetes mellitusMediators Inflamm2013201391375424381412
- Storr-PaulsenASinghAJeppesenHNorregaardJCThulesenJCorneal endothelial morphology and central thickness in patients with type II diabetes mellitusActa Ophthalmol201492215816023387877
- MisraSLGohYWPatelDVRileyAFMcGheeCNCorneal micro-structural changes in nerve fiber, endothelial and epithelial density after cataract surgery in patients with diabetes mellitusCornea201534217718125474233
- DhasmanaRSinghIPNagpalRCCorneal changes in diabetic patients after manual small incision cataract surgeryJ Clin Diagn Res201484VC03VC0624959498
- LassJHRiddlesworthTDGalRLCornea Donor Study Research GroupThe effect of donor diabetes history on graft failure and endothelial cell density 10 years after penetrating keratoplastyOphthalmology2015122344845625439611
- PritchardNEdwardsKRussellAWPerkinsBAMalikRAEfronNCorneal confocal microscopy predicts 4-year incident peripheral neuropathy in type 1 diabetesDiabetes Care201538467167525573881
- MisraSLCraigJPPatelDVIn vivo confocal microscopy of corneal nerves: an ocular biomarker for peripheral and cardiac autonomic neuropathy in type 1 diabetes mellitusInvest Ophthalmol Vis Sci20155695060506526241393
- PetropoulosINAlamUFadaviHCorneal nerve loss detected with corneal confocal microscopy is symmetrical and related to the severity of diabetic polyneuropathyDiabetes Care201336113646365123877983
- PritchardNEdwardsKDehghaniCLongitudinal assessment of neuropathy in type 1 diabetes using novel ophthalmic markers (LANDMark): study design and baseline characteristicsDiabetes Res Clin Pract2014104224825624629408
- PritchardNDehghaniCEdwardsKUtility of assessing nerve morphology in central cornea versus whorl area for diagnosing diabetic peripheral neuropathyCornea201534775676125909237
- PetropoulosINFerdousiMMarshallAThe inferior whorl for detecting diabetic peripheral neuropathy using corneal confocal microscopyInvest Ophthalmol Vis Sci20155642498250425783609
- QuJHLiLTianLZhangXYThomasRSunXGEpithelial changes with corneal punctate epitheliopathy in type 2 diabetes mellitus and their correlation with time to healingBMC Ophthalmol2018181129301512
- LagaliNSAllgeierSGuimarãesPReduced corneal nerve fiber density in type 2 diabetes by wide-area mosaic analysisInvest Ophthalmol Vis Sci201758146318632729242906
- SrinivasanSDehghaniCPritchardNCorneal and retinal neuronal degeneration in early stages of diabetic retinopathyInvest Ophthalmol Vis Sci201758146365637329260193
- BitirgenGOzkagniciAMalikRAKerimogluHCorneal nerve fibre damage precedes diabetic retinopathy in patients with type 2 diabetes mellitusDiabet Med201431443143824117485
- SatoEMoriFIgarashiSCorneal advanced glycation end products increase in patients with proliferative diabetic retinopathyDiabetes Care200124347948211289471
- StuardWLTitoneRRobertsonDMTear levels of insulin-like growth factor binding protein 3 correlate with subbasal nerve plexus changes in patients with type 2 diabetes mellitusInvest Ophthalmol Vis Sci201758146105611229214310
- DiGDuXQiXMesenchymal stem cells promote diabetic corneal epithelial wound healing through TSG-6–dependent stem cell activation and macrophage switchInvest Ophthalmol Vis Sci201758104344435428810264
- EhmkeTLeckeltJReichardMIn vivo nonlinear imaging of corneal structures with special focus on BALB/c and streptozotocin-diabetic Thy1-YFP miceExp Eye Res201614613714426677758
- LiCYangMWangXGlutazumab, a novel long-lasting GLP-1/anti-GLP-1R antibody fusion protein, exerts anti-diabetic effects through targeting dual receptor binding sitesBiochem Pharmacol2018150465329355505
- Abdul-HamidMMoustafaNAmelioration of alloxan-induced diabetic keratopathy by beta-caroteneExp Toxicol Pathol2014661495924129090
- ShevalyeHYorekMSCoppeyLJEffect of enriching the diet with menhaden oil or daily treatment with resolvin D1 on neuropathy in a mouse model of type 2 diabetesJ Neurophysiol2015114119920825925322
- DavidsonEPCoppeyLJShevalyeHObrosovAKardonRHYorekMAImpaired corneal sensation and nerve loss in a type 2 rat model of chronic diabetes is reversible with combination therapy of menhaden oil, α-lipoic acid, and enalaprilCornea201736672573128476051
- KramerovAALjubimovAVStem cell therapies in the treatment of diabetic retinopathy and keratopathyExp Biol Med (Maywood)2016241655956826454200
- LjubimovAVShawLCLi CalziSThe vascular stem cellDarttDABesharseJCDanaREncyclopedia of the EyeSan Diego, CAElsevier2010289299
- ShawLCNeuMBGrantMBCell-based therapies for diabetic retinopathyCurr Diab Rep20111126527421611766
- KojimaHKimJChanLEmerging roles of hematopoietic cells in the pathobiology of diabetic complicationsTrends Endocrinol Metab201425417818724507996
- MegawRDhillonBStem cell therapies in the management of diabetic retinopathyCurr Diab Rep201414749850624796933
- SaghizadehMDibCMBrunkenWJLjubimovAVNormalization of wound healing and stem cell marker patterns in organ-cultured human diabetic corneas by gene therapy of limbal cellsExp Eye Res2014129667325446319
- SaghizadehMEpifantsevaIHemmatiDMGhiamCABrunkenWJLjubimovAVEnhanced wound healing, kinase and stem cell marker expression in diabetic organ-cultured human corneas upon MMP-10 and cathepsin F gene silencingInvest Ophthalmol Vis Sci201354138172818024255036
- KulkarniMLeszczynskaAWeiGGenome-wide analysis suggests a differential microRNA signature associated with normal and diabetic human corneal limbusSci Rep201771344828615632
- LambiaseAAloeLMantelliFCapsaicin-induced corneal sensory denervation and healing impairment are reversed by NGF treatmentInvest Ophthalmol Vis Sci201253138280828723154458
- Blanco-MezquitaTMartinez-GarciaCProençaRNerve growth factor promotes corneal epithelial migration by enhancing expression of matrix metalloprotease-9Invest Ophthalmol Vis Sci20135463880389023640040
- BianFQiHMaPAn immunoprotective privilege of corneal epithelial stem cells against Th17 inflammatory stress by producing glial cell-derived neurotrophic factorStem Cells201028122172218120936708
- ChenJChenPBackmanLJZhouQDanielsonPCiliary neurotrophic factor promotes the migration of corneal epithelial stem/progenitor cells by up-regulation of MMPs through the phosphorylation of AktSci Rep201662587027174608
- DiGQiXZhaoXZhangSDanielsonPZhouQCorneal epithelium-derived neurotrophic factors promote nerve regenerationInvest Ophthalmol Vis Sci201758114695470228910445
- ParkJHKangSSKimJYTchahHNerve growth factor attenuates apoptosis and inflammation in the diabetic corneaInvest Ophthalmol Vis Sci201657156767677527978558
- BikbovaGOshitariTBabaTYamamotoSNeuronal changes in the diabetic cornea: perspectives for neuroprotectionBiomed Res Int20162016514082328044131
- ZhangMZhouQLuoYNguyenTRosenblattMIGuaiquilVHSemaphorin3A induces nerve regeneration in the adult cornea – a switch from its repulsive role in developmentPLoS One2018131e019196229370308
- SacchettiMLambiaseADiagnosis and management of neurotrophic keratitisClin Ophthalmol2014857157924672223
- Alvarez-RiveraFConcheiroAAlvarez-LorenzoCEpalrestat-loaded silicone hydrogels as contact lenses to address diabetic-eye complicationsEur J Pharm Biopharm201812212613629079419
- ChenHFYeungLYangKJSunCCPersistent corneal epithelial defect after pars plana vitrectomyRetina201636114815526166798
- FaiSAhemAMustaphaMMohd NohUKBastionMCRandomized controlled trial of topical insulin for healing corneal epithelial defects induced during vitreoretinal surgery in diabeticsAsia Pac J Ophthalmol (Phila)20176541842428828764
- SosneGRimmerDKleinmanHKOuslerGThymosin beta 4: a potential novel therapy for neurotrophic keratopathy, dry eye, and ocular surface diseasesVitam Horm201610227730627450739
- YangLDiGQiXSubstance P promotes diabetic corneal epithelial wound healing through molecular mechanisms mediated via the neurokinin-1 receptorDiabetes201463124262427425008176
- DiGQiXZhaoXZhangSZhouQEfficacy of sodium hyaluronate in murine diabetic ocular surface diseasesCornea20173691133113828644234
- MorishigeNUemuraAMoritaYNishidaTPromotion of corneal epithelial wound healing in diabetic rats by the fibronectin-derived peptide PHSRNCornea201736121544154828834817
- HeJPhamTLKakazuABazanHEPRecovery of corneal sensitivity and increase in nerve density and wound healing in diabetic mice after PEDF plus DHA treatmentDiabetes20176692511252028592408
- GuoCLiMQiXIntranasal delivery of nanomicelle curcumin promotes corneal epithelial wound healing in streptozotocin-induced diabetic miceSci Rep201662975327405815
- AtibaAWasfyTAbdoWGhoneimAKamalTShukryMAloe vera gel facilitates re-epithelialization of corneal alkali burn in normal and diabetic ratsClin Ophthalmol201592019202626604672
- WangWDespanieJShiPLacritin-mediated regeneration of the corneal epithelia by protein polymer nanoparticlesJ Mater Chem B20142468131814125530855
- ZhouQChenPDiGCiliary Neurotrophic Factor Promotes the Activation of Corneal Epithelial Stem/Progenitor Cells and Accelerates Corneal Epithelial Wound HealingStem Cells2015331566157625546438
- WaiteJHBeethamWPThe visual mechanism in diabetesmellitus (a comparative study of 2002 diabetics, and 457 non-diabetics for control)N Engl J Med1935212367443
- HenkindPWiseGNDescemet’s wrinkles in diabetesAm J Ophthalmol19615237137413713328