Phase III trials examining the efficacy of cetirizine ophthalmic solution 0.24% compared to vehicle for the treatment of allergic conjunctivitis in the conjunctival allergen challenge model

Edward J Meier1 Apex Eye, Mason, OH, USA

Gail L Torkildsen2 Andover Eye, Andover, MA, USA

Paul J Gomes3 Allergy, Ora, Inc., Andover, MA, USA

Mark C Jasek4 Eyevance Pharmaceuticals, TX, USA, [email protected]Correspondence[email protected]

Pages 2617-2628 | Published online: 13 Dec 2018

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BieloryLAllergic and immunologic disorders of the eye. Part II: ocular allergyJ Allergy Clin Immunol200010661019103211112882
PubMed Web of Science ®Google Scholar
BurbachGJHeinzerlingLMRöhneltCRagweed sensitization in Europe – GA(2)LEN study suggests increasing prevalenceAllergy200964466466519210367
PubMed Web of Science ®Google Scholar
La RosaMLionettiEReibaldiMAllergic conjunctivitis: a comprehensive review of the literatureItal J Pediatr201339181823497516
PubMed Web of Science ®Google Scholar
BaconASAhluwaliaPIraniAMTear and conjunctival changes during the allergen-induced early- and late-phase responsesJ Allergy Clin Immunol2000106594895411080719
PubMed Web of Science ®Google Scholar
CiprandiGBuscagliaSPesceGPBagnascoMCanonicaGWOcular challenge and hyperresponsiveness to histamine in patients with allergic conjunctivitisJ Allergy Clin Immunol1993916122712308099594
PubMed Web of Science ®Google Scholar
EhlersWHDonshikPCAllergic ocular disorders: a spectrum of diseasesClao J19921821171241606674
PubMedGoogle Scholar
GomesPJTrends in prevalence and treatment of ocular allergyCurr Opin Allergy Clin Immunol201414545145625115683
PubMed Web of Science ®Google Scholar
AbelsonMBChambersWASmithLMConjunctival allergen challenge. A clinical approach to studying allergic conjunctivitisArch Ophthalmol1990108184882297337
PubMed Web of Science ®Google Scholar
NakataniHAlcaftadine 0.25% versus olopatadine 0.1% in preventing cedar pollen allergic conjunctivitis in JapanA Randomized Study2018
Google Scholar
MclaurinENarvekarAGomesPAdewaleATorkildsenGPhase 3 randomized double-masked study of efficacy and safety of once-daily 0.77% olopatadine hydrochloride ophthalmic solution in subjects with allergic conjunctivitis using the conjunctival allergen challenge modelCornea201534101245125126266427
PubMed Web of Science ®Google Scholar
MclaurinEBergmannMNarvekarAAdewaleAGomesPJTorkildsenGPooled analysis of two studies evaluating efficacy and safety of olopatadine hydrochloride 0.77% in patients with allergic conjunctivitisClinical Ophthalmology (Auckland, NZ.)20171110891097
Web of Science ®Google Scholar
TorkildsenGAbelsonMBGomesPJMclaurinEPottsSLMahFSvehicle-controlled, Phase 2 clinical trial of a sustained-release dexamethasone intracanalicular insert in a chronic allergen challenge modelJ Ocul Pharmacol Ther2017332799028072552
PubMed Web of Science ®Google Scholar
CavetMEGomesPJCarrWWWilliamsJIBepotastine besilate ophthalmic solution 1.5% for alleviating nasal symptoms in patients with allergic conjunctivitisJ Asthma Allergy201811293929615844
PubMed Web of Science ®Google Scholar
AbelsonMBShettySKorchakMButrusSISmithLMAdvances in pharmacotherapy for allergic conjunctivitisExpert Opin Pharmacother20151681219123125943976
PubMed Web of Science ®Google Scholar
Johnson & Johnson Consumer Companies IZyrtec The #1 Allergist Recommended Brand* Available from: http://www.multivu.com/assets/52078/documents/Zyrtec-fact-sheet-99-original.pdf2011
Google Scholar
FDAPerscribing Information for Zerviate TM Available from: https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/208694s000lbl.pdf2017
Google Scholar
ZhangLChengLHongJThe clinical use of cetirizine in the treatment of allergic rhinitisPharmacology2013921–2142523867423
PubMed Web of Science ®Google Scholar
PortnoyJMDinakarCReview of cetirizine hydrochloride for the treatment of allergic disordersExpert Opin Pharmacother20045112513514680442
PubMed Web of Science ®Google Scholar
WhiteMVThe role of histamine in allergic diseasesJ Allergy Clin Immunol1990864 Pt 25996051699987
PubMed Web of Science ®Google Scholar
LanierBQAbelsonMBBergerWEComparison of the efficacy of combined fluticasone propionate and olopatadine versus combined fluticasone propionate and fexofenadine for the treatment of allergic rhinoconjunctivitis induced by conjunctival allergen challengeClin Ther20022471161117412182260
PubMed Web of Science ®Google Scholar
SpanglerDLAbelsonMBOberAGotnesPJRandomized, double-masked comparison of olopatadine ophthalmic solution, mometasone furoate monohydrate nasal spray, and fexofenadine hydrochloride tablets using the conjunctival and nasal allergen challenge modelsClin Ther20032582245226714512132
PubMed Web of Science ®Google Scholar
NakataniHGomesPBradfordRGuoQSafyanEHollanderDAAlcaftadine 0.25% versus Olopatadine 0.1% in preventing cedar pollen allergic conjunctivitis in Japan: a randomized studyOcul Immunol Inflamm2018110
Web of Science ®Google Scholar
MclaurinEBMarsicoNPAckermanSLOcular itch relief with alcaftadine 0.25% versus olopatadine 0.2% in allergic conjunctivitis: pooled analysis of two multicenter randomized clinical trialsAdv Ther201431101059107125260889
PubMed Web of Science ®Google Scholar
AckermanSD’AmbrosioFGreinerJVVillanuevaLCiolinoJBHollanderDAA multicenter evaluation of the efficacy and duration of action of alcaftadine 0.25% and olopatadine 0.2% in the conjunctival allergen challenge modelJ Asthma Allergy20136435224109191
PubMedGoogle Scholar
OnoSJAbelsonMBAllergic conjunctivitis: update on pathophysiology and prospects for future treatmentJ Allergy Clin Immunol2005115111812215637556
PubMed Web of Science ®Google Scholar

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Phase III trials examining the efficacy of cetirizine ophthalmic solution 0.24% compared to vehicle for the treatment of allergic conjunctivitis in the conjunctival allergen challenge model

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