Effects of Intense Pulsed Light on Tear Film TGF-β and Microbiome in Ocular Rosacea with Dry Eye

References

• Dana R, Bradley JL, Guerin A, et al. Estimated prevalence and incidence of dry eye disease based on coding analysis of a large, all-age United States health care system. Am J Ophthalmol. 2019;202:47–54. doi:10.1016/j.ajo.2019.01.026
   PubMed Web of Science ®Google Scholar
• Chew CK, Jansweijer C, Tiffany JM, Dikstein S, Bron AJ. An instrument for quantifying meibomian lipid on the lid margin: the Meibometer. Curr Eye Res. 1993;12(3):247–254. doi:10.3109/02713689308999470
   PubMed Web of Science ®Google Scholar
• Arita R, Morishige N, Fujii T, et al. Tear interferometric patterns reflect clinical tear dynamics in dry eye patients. Invest Ophthalmol Vis Sci. 2016;57(8):3928–3934. doi:10.1167/iovs.16-19788
   PubMed Web of Science ®Google Scholar
• Nelson JD, Shimazaki J, Benitez-del-Castillo JM, et al. The international workshop on meibomian gland dysfunction: report of the definition and classification subcommittee. Invest Ophthalmol Vis Sci. 2011;52(4):1930–1937. doi:10.1167/iovs.10-6997b
   PubMed Web of Science ®Google Scholar
• Bron AJ, de Paiva CS, Chauhan SK, et al. TFOS DEWS II pathophysiology report. Ocul Surf. 2017;15(3):438–510. doi:10.1016/j.jtos.2017.05.011
   PubMed Web of Science ®Google Scholar
• Jones L, Downie LE, Korb D, et al. TFOS DEWS II management and therapy report. Ocul Surf. 2017;15(3):575–628. doi:10.1016/j.jtos.2017.05.006
   PubMed Web of Science ®Google Scholar
• Liu R, Rong B, Tu P, et al. Analysis of cytokine levels in tears and clinical correlations after intense pulsed light treating meibomian gland dysfunction. Am J Ophthalmol. 2017;183:81–90. doi:10.1016/j.ajo.2017.08.021
   PubMed Web of Science ®Google Scholar
• Goldberg DJ. Current trends in intense pulsed light. J Clin Aesthet Dermatol. 2012;5(6):45–53.
   PubMedGoogle Scholar
• Toyos R, Mcgill W, Briscoe D. Intense pulsed light treatment for dry eye disease due to meibomian gland dysfunction; a 3-year retrospective study. Photomed Laser Surg. 2015;33(1):41–46. doi:10.1089/pho.2014.3819
   PubMed Web of Science ®Google Scholar
• Gupta PK, Vora GK, Matossian C, Kim M, Stinnett S. Outcomes of intense pulsed light therapy for treatment of evaporative dry eye disease. Can J Ophthalmol. 2016;51(4):249–253. doi:10.1016/j.jcjo.2016.01.005
   PubMed Web of Science ®Google Scholar
• Vegunta S, Patel D, Shen JF. Combination therapy of intense pulsed light therapy and meibomian gland expression (IPL/MGX) can improve dry eye symptoms and meibomian gland function in patients with refractory dry eye: a retrospective analysis. Cornea. 2016;35(3):318–322. doi:10.1097/ICO.0000000000000735
   PubMed Web of Science ®Google Scholar
• Vora GK, Gupta PK. Intense pulsed light therapy for the treatment of evaporative dry eye disease. Curr Opin Ophthalmol. 2015;26(4):314–318. doi:10.1097/ICU.0000000000000166
   PubMed Web of Science ®Google Scholar
• Arita R, Mizoguchi T, Fukuoka S, Morishige N. Multicenter study of intense pulsed light therapy for patients with refractory meibomian gland dysfunction. Cornea. 2018;37(12):1566–1571. doi:10.1097/ICO.0000000000001687
   PubMed Web of Science ®Google Scholar
• Dell SJ. Intense pulsed light for evaporative dry eye disease. Clin Ophthalmol (Auckland, NZ). 2017;11:1167–1173. doi:10.2147/OPTH.S139894
   PubMed Web of Science ®Google Scholar
• Dell SJ, Gaster RN, Barbarino SC, Cunningham DN. Prospective evaluation of intense pulsed light and meibomian gland expression efficacy on relieving signs and symptoms of dry eye disease due to meibomian gland dysfunction. Clin Ophthalmol (Auckland, NZ). 2017;11:817–827. doi:10.2147/OPTH.S130706
   PubMed Web of Science ®Google Scholar
• Craig JP, Chen YH, Turnbull PRK. Prospective trial of intense pulsed light for the treatment of meibomian gland dysfunction. Invest Ophthalmol Vis Sci. 2015;56(3):1965–1970. doi:10.1167/iovs.14-15764
   PubMed Web of Science ®Google Scholar
• Guilloto CS, Garcia MJL, Colmenero RE. Effect of pulsed laser light in patients with dry eye syndrome. Arch Soc Esp Oftalmol. 2017;92(11):509–515. doi:10.1016/j.oftal.2016.12.018
   Google Scholar
• Jiang X, Lv H, Song H, et al. Evaluation of the safety and effectiveness of intense pulsed light in the treatment of meibomian gland dysfunction. J Ophthalmol. 2016;2016:1910694. doi:10.1155/2016/1910694
   PubMed Web of Science ®Google Scholar
• Milner MS, Beckman KA, Luchs JI, et al. Dysfunctional tear syndrome: dry eye disease and associated tear film disorders - new strategies for diagnosis and treatment. Curr Opin Ophthalmol. 2017;27(Suppl1):3–47. doi:10.1097/01.icu.0000512373.81749.b7
   PubMed Web of Science ®Google Scholar
• Lam H, Bleiden L, de Paiva CS, Farley W, Stern ME, Pflugfelder SC. Tear cytokine profiles in dysfunctional tear syndrome. Am J Ophthalmol. 2009;147(2):198–205. e191. doi:10.1016/j.ajo.2008.08.032
   PubMed Web of Science ®Google Scholar
• Massingale ML, Li X, Vallabhajosyula M, Chen D, Wei Y, Asbell PA. Analysis of Inflammatory cytokines in the tears of dry eye patients. Cornea. 2009;28(9):1023–1027. doi:10.1097/ICO.0b013e3181a16578
   PubMed Web of Science ®Google Scholar
• Jackson DC, Zeng W, Wong CY, et al. Tear interferon-gamma as a biomarker for evaporative dry eye disease. Invest Ophthalmol Vis Sci. 2016;57(11):4824–4830. doi:10.1167/iovs.16-19757
   PubMed Web of Science ®Google Scholar
• Massagué J. The transforming growth factor-beta family. Annu Rev Cell Biol. 1990;6:597–641. doi:10.1146/annurev.cb.06.110190.003121
   PubMedGoogle Scholar
• Sporn MB, Roberts AB. Transforming growth factor—β: multiple actions and potential clinical applications. JAMA. 1989;262(7):938–941. doi:10.1001/jama.1989.03430070086036
   PubMed Web of Science ®Google Scholar
• Ali MM, Porter RM, Gonzalez ML. Intense pulsed light enhances transforming growth factor beta1/Smad3 signaling in acne-prone skin. J Cosmet Dermatol. 2013;12(3):195–203. doi:10.1111/jocd.12045
   PubMed Web of Science ®Google Scholar
• Pflugfelder SC, Jones D, Ji Z, Afonso A, Monroy D. Altered cytokine balance in the tear fluid and conjunctiva of patients with Sjögren’s syndrome keratoconjunctivitis sicca. Curr Eye Res. 1999;19(3):201–211. doi:10.1076/ceyr.19.3.201.5309
   PubMed Web of Science ®Google Scholar
• Zhang L, Su Z, Zhang Z, Lin J, Li D-Q, Pflugfelder SC. Effects of azithromycin on gene expression profiles of proinflammatory and anti-inflammatory mediators in the eyelid margin and conjunctiva of patients with meibomian gland disease. JAMA Ophthalmol. 2015;133(10):1117–1123. doi:10.1001/jamaophthalmol.2015.2326
   PubMed Web of Science ®Google Scholar
• Mukamal R. Microbiome of the eye. Am Acad Ophthalmol. 2019.
   Google Scholar
• Lu LJ, Liu J. Human microbiota and ophthalmic disease. Yale J Biol Med. 2016;89(3):325–330.
   PubMedGoogle Scholar
• Miller D, Iovieno A. The role of microbial flora on the ocular surface. Curr Opin Allergy Clin Immunol. 2009;9(5):466–470. doi:10.1097/ACI.0b013e3283303e1b
   PubMed Web of Science ®Google Scholar
• Doan T, Akileswaran L, Andersen D, et al. Paucibacterial microbiome and resident DNA virome of the healthy conjunctiva. Invest Ophthalmol Vis Sci. 2016;57(13):5116–5126. doi:10.1167/iovs.16-19803
   PubMed Web of Science ®Google Scholar
• Graham JE, Moore JE, Jiru X, et al. Ocular pathogen or commensal: a PCR-based study of surface bacterial flora in normal and dry eyes. Invest Ophthalmol Vis Sci. 2007;48(12):5616–5623. doi:10.1167/iovs.07-0588
   PubMed Web of Science ®Google Scholar
• Oakley A Fitzpatrick skin phototype DermNet NZ. 2012.
   Google Scholar
• Real D, Hwang F, Bunya V. Dry eye syndrome questionnaires. Am Acad Ophthalmol. 2020.
   Google Scholar
• EMP Ontology (EMPO). Earth microbiome project; 2020. Available from: https://earthmicrobiome.org/protocols-and-standards/empo/. Accessed January 05, 2021
   Google Scholar
• Rong B, Tang Y, Liu R, et al. Long-term effects of intense pulsed light combined with meibomian gland expression in the treatment of meibomian gland dysfunction. Photomed Laser Surg. 2018;36(10):562–567. doi:10.1089/pho.2018.4499
   PubMed Web of Science ®Google Scholar
• Rong B, Tang Y, Tu P, et al. Intense pulsed light applied directly on eyelids combined with meibomian gland expression to treat meibomian gland dysfunction. Photomed Laser Surg. 2018;36(6):326–332. doi:10.1089/pho.2017.4402
   PubMed Web of Science ®Google Scholar
• Caporaso JG, Lauber CL, Walters WA, et al. Global patterns of 16S rRNA diversity at a depth of millions of sequences per sample. Proc Natl Acad Sci. 2011;108(Supplement 1):4516–4522. doi:10.1073/pnas.1000080107
   PubMed Web of Science ®Google Scholar