97
Views
1
CrossRef citations to date
0
Altmetric
Original Research

Is Interferon α-2b 1 MillionIU/mL Truly Better Than Tacrolimus 0.03% for Steroid-Resistant VKC ?: Our 2-Year Experience at a Tertiary Health-Care Centre

, , , ORCID Icon &
Pages 2993-2999 | Published online: 14 Jul 2021

References

  • Vichyanond P, Pacharn P, Pleyer U, Leonardi A. Vernal keratoconjunctivitis: a severe allergic eye disease with remodelling changes. Pediatr Allergy Immunol. 2014;25:314–322. doi:10.1111/pai.12197
  • Leonardi A, Busca F, Moterle L, et al. Case series of 406 vernal keratoconjunctivitis patients: a demographic and epidemiological study. Acta Ophthalmol Scand. 2006;84:406–410. doi:10.1111/j.1600-0420.2005.00622.x
  • Bonini S, Bonini S, Lambiase A, et al. Vernal keratoconjunctivitis revisited; a case series of 195 patients with long term follow-up. Ophthalmology. 2000;107(6):1157–1163. doi:10.1016/S0161-6420(00)00092-0
  • Pucci N, Novembre E, Lombardi E, et al. Atopy and serum eosinophil cationic protein in 110 white children with vernal keratoconjunctivitis: differences between tarsal and limbal forms. Clin Exp Allergy. 2003;33(3):325–330. doi:10.1046/j.1365-2222.2003.01538.x
  • Lambiase A, Minchiotti S, Leonardi A, et al. Prospective, multicenter demographic and epidemiological study on vernal keratoconjunctivitis: a glimpse of ocular surface in Italian population. Ophthalmic Epidemiol. 2009;16(1):38–41. doi:10.1080/09286580802573177
  • Bremond-Gignac D, Donadieu J, Leonardi A, et al. Prevalence of vernal keratoconjunctivitis: a rare disease? Br J Ophthalmol. 2008;92(8):1097–1102. doi:10.1136/bjo.2007.117812
  • Clark AF. Basic sciences in clinical glaucoma: steroids, ocular hypertension, and glaucoma. J Glaucoma. 1995;4(5):354–369. doi:10.1097/00061198-199510000-00010
  • Bielory L. Allergic and immunologic disorders of the eye. Part II: ocular allergy. J Allergy Clin Immunol. 2000;106(6):1019–1032. doi:10.1067/mai.2000.111238
  • Sacchetti M, Baiardini I, Lambiase A, et al. Development and testing of the quality of life in children with vernal keratoconjunctivitis questionnaire. Am J Ophthalmol. 2007;144(4):557–563. doi:10.1016/j.ajo.2007.06.028
  • Schreiber SL, Crabtree GR. The mechanism of action of cyclosporine A and FK 506. Immunol Today. 1992;13:136–142. doi:10.1016/0167-5699(92)90111-J
  • Sakuma S, Higashi Y, Sato N, et al. Tacrolimus suppressed the production of cytokines involved in atopic dermatites by direct stimulation of human PBMC system. (Comparison with steroids). Int Immunopharmacol. 2001;1:1219–1226. doi:10.1016/S1567-5769(01)00059-5
  • Mackensen F, Max R, Becker MD. IFN therapy for ocular disease. Curr Opin Ophthalmol. 2006;17:567–573. doi:10.1097/ICU.0b013e328010ab35
  • Bleik JH, Tabbara KF. Topical cyclosporine in vernal keratoconjunctivitis. Ophthalmology. 1991;98(11):1679–1684. doi:10.1016/S0161-6420(91)32069-4
  • Muller GG, Jose NK, de Castro RS. Topical tacrolimus 0.03% as sole therapy in vernal keratoconjunctivitis: a randomized double-masked study. Eye Contact Lens. 2014;40(2):79–83. doi:10.1097/ICL.0000000000000001
  • Bonini S. Atopic keratoconjunctivitis. Allergy. 2004;59(Suppl.78):71–73. doi:10.1111/j.1398-9995.2004.00570.x
  • Vichyanond P, Kosrirukvongs P. Use of cyclosporine A and tacrolimus in treatment of vernal keratoconjunctivitis. Curr Allergy Asthma Rep. 2013;13(3):308–314. doi:10.1007/s11882-013-0345-0
  • Pucci N, Caputo R, Di Grande L, et al. Tacrolimus vs. cyclosporine eyedrops in severe cyclosporine-resistant vernal keratoconjunctivitis: a randomized, comparative, double-blind, crossover study. Pediatr Allergy Immunol. 2015;26(3):256–261. doi:10.1111/pai.12360
  • Fiorentini S, Khurram D. Therapeutic effects of topical 0.03% tacrolimus ointment in children with refractory vernal keratoconjunctivitis in Middle East. Saudi J Ophthalmol. 2019;33:117–120. doi:10.1016/j.sjopt.2019.04.001
  • Turan-Vural E, Acar BT, Acar S. The efficacy of topical IFN α 2b treatment in refractory vernal keratoconjunctivitis. Ocul Immunol Inflamm. 2012;20:125–129. doi:10.3109/09273948.2012.656877
  • Zanjani H, Aminifard M, Ghafourian A, et al. Comparative evaluation of tacrolimus versus IFN Α-2b eye drops in the treatment of vernal keratoconjunctivitis. Cornea. 2017;36:675–678. doi:10.1097/ICO.0000000000001200
  • Gupta PC, Ram J. Comment: comparative evaluation of tacrolimus versus interferon alpha-2b eye drops in the treatment of vernal keratoconjunctivitis: a Randomized, Double-Masked Study. Cornea. 2018;37:e1.