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Clinical Ophthalmology Volume 15, 2021 - Issue
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Research Letter

Changes in Tear Proteome After Acupuncture Treatment in Dry Eye

Louis Tong1 Ocular Surface Research Group, Singapore Eye Research Institute, Singapore;2 Corneal and External Eye Disease Service, Singapore National Eye Centre, Singapore;3 Eye-Academic Clinical Program, Duke-National University of Singapore (NUS) Medical School, Singapore;4 Department of Ophthalmology, Yong Loo Lin School of Medicine, NUS, SingaporeCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-3986-6552
ORCID Icon,
Lei Zhou3 Eye-Academic Clinical Program, Duke-National University of Singapore (NUS) Medical School, Singapore;4 Department of Ophthalmology, Yong Loo Lin School of Medicine, NUS, Singapore;5 Ocular Proteomics Platform, Singapore Eye Research Institute, SingaporeCorrespondence[email protected]
,
Siew Kwan Koh5 Ocular Proteomics Platform, Singapore Eye Research Institute, Singapore
,
Yan Gao5 Ocular Proteomics Platform, Singapore Eye Research Institute, Singapore
,
Hla Myint Htoon1 Ocular Surface Research Group, Singapore Eye Research Institute, Singapore;3 Eye-Academic Clinical Program, Duke-National University of Singapore (NUS) Medical School, Singapore
,
AiHua Hou1 Ocular Surface Research Group, Singapore Eye Research Institute, Singapore;3 Eye-Academic Clinical Program, Duke-National University of Singapore (NUS) Medical School, Singapore
,
Lu Deng6 Department of Statistics and Applied Probability, Faculty of Science, NUS, Singapore
,
Qi-Ping Wei7 Beijing University of Chinese Medicine, Beijing, People’s Republic of China
&
Pat Lim8 Singapore Chung Hwa Medical Institution, Singapore
 show all
Pages 4585-4590 | Published online: 01 Dec 2021

References

  • Craig JP, Nichols KK, Akpek EK, et al. TFOS DEWS II definition and classification report. Ocul Surf. 2017;15(3):276–283. doi:10.1016/j.jtos.2017.05.008
  • Liu Q, Liu J, Ren C, et al. Proteomic analysis of tears following acupuncture treatment for menopausal dry eye disease by two-dimensional nano-liquid chromatography coupled with tandem mass spectrometry. Int J Nanomedicine. 2017;12:1663–1671. doi:10.2147/IJN.S126968
  • Ji YW, Kim HM, Ryu SY, et al. Changes in human tear proteome following topical treatment of dry eye disease: cyclosporine a versus diquafosol tetrasodium. Invest Ophthalmol Vis Sci. 2019;60(15):5035–5044. doi:10.1167/iovs.19-27872
  • Tong L, Htoon HM, Hou AH, et al. Acupuncture and herbal formulation compared with artificial tears alone: evaluation of dry eye symptoms and associated tests in randomized clinical trial. BMJ Open Ophthalmol. 2018;3(1):e000150. doi:10.1136/bmjophth-2018-000150
  • Tong L, Zhou L, Beuerman R, et al. Effects of punctal occlusion on global tear proteins in patients with dry eye. Ocul Surf. 2017;15(4):736–741. doi:10.1016/j.jtos.2017.04.002
  • Zhou L, Beuerman RW, Chan CM, et al. Identification of tear fluid biomarkers in dry eye syndrome using iTRAQ quantitative proteomics. J Proteome Res. 2009;8(11):4889–4905. doi:10.1021/pr900686s
  • Shi JL, Miao WH. [Effects of acupuncture on lactoferrin content in tears and tear secretion in patients suffering from dry eyes: a randomized controlled trial]. Zhong Xi Yi Jie He Xue Bao. 2012;10(9):1003–1008. doi:10.3736/jcim20120909. Chinese.
  • Qiu X, Gong L, Sun X, et al. Efficacy of acupuncture and identification of tear protein expression changes using iTRAQ quantitative proteomics in rabbits. Curr Eye Res. 2011;36(10):886–894. doi:10.3109/02713683.2011.601843
  • Gong L, Sun X. Treatment of intractable dry eyes: tear secretion increase and morphological changes of the lacrimal gland of rabbit after acupuncture. Acupunct Electrother Res. 2007;32(3–4):223–233. doi:10.3727/036012907815844011

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