151
Views
1
CrossRef citations to date
0
Altmetric
Original Research

Two-Year Outcome of Aflibercept Intravitreal Injection in Vitrectomized Eyes with Diabetic Macular Edema

ORCID Icon, ORCID Icon, , ORCID Icon, , ORCID Icon & ORCID Icon show all
Pages 603-609 | Published online: 07 Mar 2022

References

  • Tranos PG, Wickremasinghe S, Stangos N, et al. Macular edema. Surv Ophthalmol. 2004;49:470–490. doi:10.1016/S0039-6257(04)00109-2
  • Schmidt-Erfurth U, Garcia-Arumi J, Bandello F, et al. Guidelines for the management of diabetic macular edema by the European Society of Retina Specialists (EURETINA). Ophthalmologica. 2017;237:185–222. doi:10.1159/000458539
  • Do DV, Nguyen QD, Vitti R, et al. Intravitreal aflibercept injection in diabetic macular edema patients with and without prior anti-vascular endothelial growth factor treatment: outcomes from the Phase 3 program. Ophthalmology. 2016;123:850–857. doi:10.1016/j.ophtha.2015.11.008
  • Korobelnik JF, Do DV, Schmidt-Erfurth U, et al. Intravitreal aflibercept for diabetic macular edema. Ophthalmology. 2014;121:2247–2254. doi:10.1016/j.ophtha.2014.05.006
  • Heier JS, Bressler NM, Avery RL, et al. Comparison of aflibercept, bevacizumab, and ranibizumab for treatment of diabetic macular edema: extrapolation of data to clinical practice. JAMA Ophthalmol. 2016;134:95–99. doi:10.1001/jamaophthalmol.2015.4110
  • Wells JA, Glassman AR, Ayala AR, et al. Aflibercept, bevacizumab, or ranibizumab for diabetic macular edema: two-year results from a comparative effectiveness randomized clinical trial. Ophthalmology. 2016;123:1351–1359. doi:10.1016/j.ophtha.2016.02.022
  • Bahrami B, Hong T, Schlub TE, Chang AA. Aflibercept for persistent diabetic macular edema: forty-eight-week outcomes. Retina. 2019;39:61–68. doi:10.1097/IAE.0000000000002253
  • Kulikov AN, Sosnovskii SV, Berezin RD, et al. Vitreoretinal interface abnormalities in diabetic macular edema and effectiveness of anti-VEGF therapy: an optical coherence tomography study. Clin Ophthalmol. 2017;11:1995–2002. doi:10.2147/OPTH.S146019
  • Hagenau F, Vogt D, Ziada J, et al. Vitrectomy for diabetic macular edema: optical coherence tomography criteria and pathology of the vitreomacular interface. Am J Ophthalmol. 2019;200:34–46. doi:10.1016/j.ajo.2018.12.004
  • Niwa Y, Kakinoki M, Sawada T, Wang X, Ohji M. Ranibizumab and aflibercept: intraocular pharmacokinetics and their effects on aqueous VEGF level in vitrectomized and nonvitrectomized macaque eyes. Invest Ophthalmol Vis Sci. 2015;56:6501–6505. doi:10.1167/iovs.15-17279
  • Tran THC, Erginay A, Verdun S, et al. One-year outcome of aflibercept intravitreal injection in vitrectomized eyes with diabetic macular edema. Clin Ophthalmol. 2021;15:1971–1978. doi:10.2147/OPTH.S304030
  • Turkseven Kumral E, Ercalik NY. Intravitreal ranibizumab versus aflibercept for diabetic macular edema in vitrectomized eyes: 12 month results. Semin Ophthalmol. 2021;34:1–5.
  • Avitabile T, Azzolini C, Bandello F, et al. Aflibercept in the treatment of diabetic macular edema: a review and consensus paper. Eur J Ophthalmol. 2017;27:627–639. doi:10.5301/ejo.5001053
  • Michalewska Z, Stewart MW, Landers MB, et al. Vitrectomy in the management of diabetic macular edema in treatment-naive patients. Can J Ophthalmol. 2018;53:402–407. doi:10.1016/j.jcjo.2017.10.011
  • Bressler SB, Melia M, Glassman AR, et al. Ranibizumab plus prompt or deferred laser for diabetic macular edema in eyes with vitrectomy before anti-vascular endothelial growth factor therapy. Retina. 2015;35:2516–2528. doi:10.1097/IAE.0000000000000617
  • Ciulla TA, Bracha P, Pollack J, Williams DF. Real-world outcomes of anti-vascular endothelial growth factor therapy in diabetic macular edema in the United States. Ophthalmology Retina. 2018;2:1179–1187. doi:10.1016/j.oret.2018.06.004
  • Chen YY, Chen PY, Chen FT, Chen YJ, Wang JK. Comparison of efficacy of intravitreal ranibizumab between non-vitrectomized and vitrectomized eyes with diabetic macular edema. Int Ophthalmol. 2018;38:293–299. doi:10.1007/s10792-017-0462-1
  • Wykoff CC, Shah C, Dhoot D, et al. Longitudinal retinal perfusion status in eyes with diabetic macular edema receiving intravitreal aflibercept or laser in vista study. Ophthalmology. 2019;126:1171–1180. doi:10.1016/j.ophtha.2019.03.040
  • Koyanagi Y, Yoshida S, Kobayashi Y, et al. Visual outcomes based on early response to anti-vascular endothelial growth factor treatment for diabetic macular edema. Ophthalmologica. 2018;239:94–102. doi:10.1159/000481711
  • Kakinoki M, Sawada O, Sawada T, et al. Effect of vitrectomy on aqueous VEGF concentration and pharmacokinetics of bevacizumab in macaque monkeys. Invest Ophthalmol Vis Sci. 2012;53:5877–5880. doi:10.1167/iovs.12-10164