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CLINICAL TRIAL REPORT

Evaluating a Sustained-Release Dexamethasone Insert as Adjunctive Therapy for Inflammation and Pain Post-Corneal Transplantation

, ORCID Icon & ORCID Icon
Pages 2083-2091 | Received 27 Feb 2024, Accepted 10 Jul 2024, Published online: 23 Jul 2024

References

  • Singh R, Gupta N, Vanathi M, Tandon R. Corneal transplantation in the modern era. Indian J Med Res. 2019;150(1):7–22. PMID: 31571625; PMCID: PMC6798607. doi:10.4103/ijmr.IJMR_141_19
  • Eye Bank Association of America. 2022 eye banking statistical report; 2022. Available from: https://restoresight.org/members/publications/statistical-report/#:~:text=49%2C110%20intermediate%2Dterm%20preserved%20corneas,were%20exported%20internationally%20in%202021. Accessed February 12, 2023.
  • Anshu A, Price MO, Price FW. Risk of corneal transplant rejection significantly reduced with Descemet’s membrane endothelial keratoplasty. Ophthalmology. 2012;119(3):536–540. PMID: 22218143. doi:10.1016/j.ophtha.2011.09.019
  • Price MO, Scanameo A, Feng MT, Price FW. Descemet’s membrane endothelial keratoplasty: risk of immunologic rejection episodes after discontinuing topical corticosteroids. Ophthalmology. 2016;123(6):1232–1236. PMID: 26983976. doi:10.1016/j.ophtha.2016.02.001
  • Azevedo Magalhaes O, Shalaby Bardan A, Zarei-Ghanavati M, Liu C. Literature review and suggested protocol for prevention and treatment of corneal graft rejection. Eye. 2020;34(3):442–450. PMID: 31332293; PMCID: PMC7042259. doi:10.1038/s41433-019-0517-9
  • Cruz GKP, Azevedo IC, Carvalho DP, Vitor AF, Santos VEP, Ferreira MA. Clinical and epidemiological aspects of cornea transplant patients of a reference hospital. Rev Lat Am Enfermagem. 2017;25:e2897. PMID: 28614429; PMCID: PMC5492649. doi:10.1590/1518-8345.1537.2897
  • An JA, Kasner O, Samek DA, Lévesque V. Evaluation of eyedrop administration by inexperienced patients after cataract surgery. J Cataract Refract Surg. 2014;40(11):1857–1861. PMID: 25248295. doi:10.1016/j.jcrs.2014.02.037
  • Renfro L, Snow JS. Ocular effects of topical and systemic steroids. Dermatol Clin. 1992;10(3):505–512. PMID: 1617809. doi:10.1016/S0733-8635(18)30318-8
  • Ocular therapeutix; 2021. Available from: https://www.ocutx.com/products/dextenza/. Accessed February 8, 2023.
  • Tyson SL, Bafna S, Gira JP, et al. Dextenza Study Group. Multicenter randomized Phase 3 study of a sustained-release intracanalicular dexamethasone insert for treatment of ocular inflammation and pain after cataract surgery. J Cataract Refract Surg. 2019;45(2):204–212. doi:10.1016/j.jcrs.2018.09.023
  • Walters T, Bafna S, Vold S, et al. Efficacy and safety of a sustained release dexamethasone insert for the treatment of ocular pain and inflammation after cataract surgery: results from two phase 3 studies. J Clin Exp Ophthalmol. 2016;7:4. doi:10.4172/2155-9570.1000572
  • Ibach MJ, Zimprich L, Wallin DD, Olevson C, Puls-Boever K, Thompson V. In clinic optometrist insertion of dextenza (Dexamethasone Ophthalmic Insert 0.4mg) Prior to Cataract Surgery: the PREPARE Study. Clin Ophthalmol. 2022;16:2609–2615. doi:10.2147/OPTH.S374405
  • Ibach MJ, Shafer BM, Wallin DD, Puls-Boever KR, Thompson VM, Berdahl JP. The effectiveness and safety of dextenza 0.4 mg for the treatment of postoperative inflammation and pain in patients after photorefractive keratectomy: the RESTORE trial. J Refract Surg. 2021;37(9):590–594. PMID: 34506241. doi:10.3928/1081597X-20210610-05
  • Fram N, Alsetri H, Shiler O, Paterno PJ, Cabang J. Retrospective study of a sustained-release intracanalicular dexamethasone insert for treatment of ocular inflammation after cataract and corneal surgery. Clin Ophthalmol. 2022;16:4065–4074. PMID: 36532822; PMCID: PMC9749497. doi:10.2147/OPTH.S386702
  • Jabs DA, Nussenblatt RB, Rosenbaum JT; Standardization of Uveitis Nomenclature (SUN) Working Group. Standardization of uveitis nomenclature for reporting clinical data. results of the first international workshop. Am J Ophthalmol. 2005;140(3):509–516. PMID: 16196117; PMCID: PMC8935739. doi:10.1016/j.ajo.2005.03.057