References
- ChigbuDIThe pathophysiology of ocular allergy: a reviewCont Lens Anterior Eye2009321315 quiz 43–418805042
- WongAHBargSSLeungAKSeasonal and perennial allergic conjunctivitisRecent Pat Inflamm Allergy Drug Discov20148213915325000933
- MantelliFCalderVLBoniniSThe anti-inflammatory effects of therapies for ocular allergyJ Ocul Pharmacol Ther201329978679324044620
- MishraGPTamboliVJwalaJMitraAKRecent patents and emerging therapeutics in the treatment of allergic conjunctivitisRecent Pat Inflamm Allergy Drug Discov201151263621171952
- LeonardiAAllergy and allergic mediators in tearsExp Eye Res201311710611723891862
- ChigbuDISandrasekaramudaly-BrownSOcular surface disease: a case of vernal keratoconjunctivitisCont Lens Anterior Eye2011341394420971677
- MimuraTYamagamiSKameiYGotoMMatsubaraMSpecific IgE in tear fluid and features of allergic conjunctivitisCurr Eye Res201338991792523713468
- NyeMRudnerSBieloryLEmerging therapies in allergic conjunctivitis and dry eye syndromeExpert Opin Pharmacother201314111449146523822862
- RidoloEMontagniMCaminatiMSennaGIncorvaiaCCanonicaGWEmerging drugs for allergic conjunctivitisExpert Opin Emerg Drugs201419229130224661261
- OnoSJLaneKComparison of effects of alcaftadine and olopatadine on conjunctival epithelium and eosinophil recruitment in a murine model of allergic conjunctivitisDrug Des Devel Ther201157784
- ChigbuDIStructure, function and immunology of the ocular surfaceAllergic Disorders of the Ocular SurfaceNew YorkNova Science Publishers, Inc2013718
- ForresterJVXuHKuffovaLDickADMcMenaminPGDendritic cell physiology and function in the eyeImmunol Rev2010234128230420193026
- Galicia-CarreonJSantacruzCHongEJimenez-MartinezMCThe ocular surface: from physiology to the ocular allergic diseasesRev Alerg Mex201360417218324912910
- DonshikPEhlersWBallowMGiant papillary conjunctivitisImmunol Allergy Clin North Am200828183103vi18282547
- ElhersWDonshikPGiant papillary conjunctivitisCurr Opin Allergy Clin Immunol20088544544918769199
- DonshikPGiant papillary conjunctivitisTrans Am Ophthalmol Soc1994926877447886881
- KnopEKnopNAnatomy and immunology of the ocular surfaceChem Immunol Allergy200792364917264481
- IrkeçMBozkurtBEpithelial cells in ocular allergyCurr Allergy Asthma Rep20033435235712791215
- PflugfelderSSternMImmunoregulation on the ocular surface: 2nd Cullen SymposiumOcul Surf200972677719383275
- GilgerBCImmunology of the ocular surfaceVet Clin North Am Small Anim Pract2008382223231v18299004
- PaulsenFFunctional anatomy and immunological interactions of ocular surface and adnexaDev Ophthalmol200841213518453759
- IraniAMOcular mast cells and mediatorsImmunol Allergy Clin North Am20082812542v18282544
- BoniniSMiceraAIovienoALambiaseAExpression of Toll-like receptors in healthy and allergic conjunctivaOphthalmology200511291528 discussion 1529–154816023216
- RedfernRLMcDermottAMToll-like receptors in ocular surface diseaseExp Eye Res201090667968720346359
- MiceraAStampachiacchiereBAronniSdos SantosMLambiaseAToll-like receptors and the eyeCurr Opin Allergy Clin Immunol20055545145816131923
- MerglerSGarreisFSahlmüllerMCalcium regulation by thermo- and osmosensing transient receptor potential vanilloid channels (TRPVs) in human conjunctival epithelial cellsHistochem Cell Biol2012137674376122327830
- KanekoYSzallasiATransient receptor potential (TRP) channels: a clinical perspectiveBr J Pharmacol2014171102474250724102319
- TorkildsenGSheddenAThe safety and efficacy of alcaftadine 0.25% ophthalmic solution for the prevention of itching associated with allergic conjunctivitisCurr Med Res Opin201127362363121250860
- AmaralMMDavioCCeballosAHistamine improves antigen uptake and cross-presentation by dendritic cellsJ Immunol200717963425343317785776
- SaravananCBhartiSKJaggiSSinghSKHistamine H(4) receptor: a novel target for inflammation therapyMini Rev Med Chem201111214315821222579
- DamajBBBecerraCBEsberHJWenYMaghazachiAAFunctional expression of H4 histamine receptor in human natural killer cells, monocytes, and dendritic cellsJ Immunol2007179117907791518025238
- SmudaCBrycePJNew developments in the use of histamine and histamine receptorsCurr Allergy Asthma Rep20111129410021104347
- BhattHGAgrawalYKRavalHGMannaKDesaiPRHistamine H4 receptor: a novel therapeutic target for immune and allergic responsesMini Rev Med Chem201010141293130821175423
- CriadoPRCriadoRFMarutaCWMachado FilhoCHistamine, histamine receptors and antihistamines: new conceptsAn Bras Dermatol201085219521020520935
- MarsonCMTargeting the histamine H4 receptorChem Rev2011111117121715621842846
- KmiecikTOtocka-KmiecikAGorska-CiebiadaMCiebiadaMT lymphocytes as a target of histamine actionArch Med Sci20128115416122457689
- ImamachiNParkGHLeeHTRPV1-expressing primary afferents generate behavioral responses to pruritogens via multiple mechanismsProc Natl Acad Sci U S A200910627113301133519564617
- OhbayashiMManzouriBMorohoshiKFukudaKOnoSJThe role of histamine in ocular allergyAdv Exp Med Biol2010709435221618886
- AbbasAKLichtmanAHHPillaiSAllergyCellular and Molecular ImmunologyPhiladelphiaElsevier Saunders2015239264
- ButrusSPortelaROcular allergy: diagnosis and treatmentOphthalmol Clin North Am2005184485492v16314214
- ChigbuDIImmunology relevant to allergic ocular surface diseasesAllergic Disorders of the Ocular SurfaceaNew YorkNova Science Publishers, Inc20135374
- ZhengXMaPde PaivaCSTSLP and downstream molecules in experimental mouse allergic conjunctivitisInvest Ophthalmol Vis Sci20105163076308220107175
- TakaiTTSLP expression: cellular sources, triggers, and regulatory mechanismsAllergol Int201261131722270071
- DengRSuZLuFA potential link between bacterial pathogens and allergic conjunctivitis by dendritic cellsExp Eye Res201412011812624486456
- WilsonSRThéLBatiaLMThe epithelial cell-derived atopic dermatitis cytokine TSLP activates neurons to induce itchCell2013155228529524094650
- BroideDHImmunomodulation of allergic diseaseAnnu Rev Med20096027929119630573
- AbelsonMBSmithLChapinMOcular allergic disease: mechanisms, disease sub-types, treatmentOcul Surf20031312714917075644
- LeonardiADi StefanoAVicariCMotterleLBrunPHistamine H4 receptors in normal conjunctiva and in vernal keratoconjunctivitisAllergy201166101360136621545429
- BrownJWilsonTMetcalfeDThe mast cell and allergic diseases: role in pathogenesis and implications for therapyClin Exp Allergy200838141818031566
- ShimWSTakMHLeeMHTRPV1 mediates histamine-induced itching via the activation of phospholipase A2 and 12-lipoxygenaseJ Neurosci20072792331233717329430
- ChigbuDIThe management of allergic eye diseases in primary eye careCont Lens Anterior Eye200932626027219879797
- GreinerJVEdwards-SwansonKIngermanAEvaluation of alcaftadine 0.25% ophthalmic solution in acute allergic conjunctivitis at 15 minutes and 16 hours after instillation versus placebo and olopatadine 0.1%Clin Ophthalmol20115879321339800
- WadeLBieloryLRudnerSOphthalmic antihistamines and H1-H4 receptorsCurr Opin Allergy Clin Immunol201212551051622918191
- NamdarRValdezCAlcaftadine: a topical antihistamine for use in allergic conjunctivitisDrugs Today (Barc)2011471288389022348913
- BohetsHMcGowanCMannensGSchroederNEdwards-SwansonKShapiroAClinical pharmacology of alcaftadine, a novel antihistamine for the prevention of allergic conjunctivitisJ Ocul Pharmacol Ther201127218719521314437
- LinJHYamazakiMRole of P-glycoprotein in pharmacokinetics: clinical implicationsClin Pharmacokinet2003421599812489979
- LinJHLuAYInterindividual variability in inhibition and induction of cytochrome P450 enzymesAnnu Rev Pharmacol Toxicol20014153556711264468
- MahvanTDBuckleyWAHorneckerJRAlcaftadine for the prevention of itching associated with allergic conjunctivitisAnn Pharmacother2012467–81025103222811343
- ZhangYAlcaftadine Clinical Pharmacology Review, NDA 22–134Food and Drug Administration Available from: http:www.fda.gov/downloads/Drugs/DevelopmentApprovalProcess/DevelopmentResources/UCM223817.pdfAccessed July 24, 2014
- AbelsonMBLoefflerOConjunctival allergen challenge: models in the investigation of ocular allergyCurr Allergy Asthma Rep20033436336812791217
- AbelsonMBChambersWASmithLMConjunctival allergen challenge. A clinical approach to studying allergic conjunctivitisArch Ophthalmol1990108184882297337
- AckermanSD’AmbrosioFJrGreinerJVVillanuevaLCiolinoJBHollanderDAA multicenter evaluation of the efficacy and duration of action of alcaftadine 0.25% and olopatadine 0.2% in the conjunctival allergen challenge modelJ Asthma Allergy20136435224109191
- McLaurinEBMarsicoNPAckermanSLOcular itch relief with alcaftadine 0.25% versus olopatadine 0.2% in allergic conjunctivitis: pooled analysis of two multicenter randomized clinical trialsAdv Ther201431101059107125260889
- ChambersWAClinical Review of NDA 206276Food and Drug Administration Available from: http://www.fda.gov/downloads/Drugs/DevelopmentApprovalProcess/DevelopmentResources/UCM434580.pdfAccessed May 30, 2015
- AbelsonMBShettySKorchakMButrusSISmithLMAdvances in pharmacotherapy for allergic conjunctivitisExpert Opin Pharmacother20151681219123125943976
- CowdenJMZhangMDunfordPJThurmondRLThe histamine H4 receptor mediates inflammation and pruritus in Th2-dependent dermal inflammationJ Invest Dermatol201013041023103319907432