A novel intravitreal fluocinolone acetonide implant (Iluvien^®) in the treatment of patients with chronic diabetic macular edema that is insufficiently responsive to other medical treatment options: a case series

References

• KleinRKleinBEMossSEThe Wisconsin epidemiologic study of diabetic retinopathy: XV. The long-term incidence of macular edemaOphthalmology199510217167831044
   PubMed Web of Science ®Google Scholar
• YauJWRogersSLKawasakiRGlobal prevalence and major risk factors of diabetic retinopathyDiabetes Care20123555656422301125
   PubMed Web of Science ®Google Scholar
• FerrisFLIIIPatzAMacular edema. A complication of diabetic retinopathySurv Ophthalmol198428Suppl4524616379946
   PubMed Web of Science ®Google Scholar
• BhagatNGrigorianRATutelaAZarbinMADiabetic macular edema: pathogenesis and treatmentSurv Ophthalmol20095413219171208
   PubMed Web of Science ®Google Scholar
• MossSEKleinRKleinBEThe 14-year incidence of visual loss in a diabetic populationOphthalmology199810599810039627648
   PubMed Web of Science ®Google Scholar
• KleinRKleinBEMossSECruickshanksKJThe Wisconsin epidemiologic study of diabetic retinopathy: XVII. The 14-year incidence and progression of diabetic retinopathy and associated risk factors in type 1 diabetesOphthalmology1998105180118159787347
   PubMed Web of Science ®Google Scholar
• Diabetes Control and Complications Trial Research GroupProgression of retinopathy with intensive versus conventional treatment in the Diabetes Control and Complications TrialOphthalmology19951026476617724182
   PubMed Web of Science ®Google Scholar
• MassinPAudrenFHaouchineBIntravitreal triamcinolone acetonide for diabetic diffuse macular edema: preliminary results of a prospective controlled trialOphthalmology20041112218224 discussion 224–22515019365
   PubMed Web of Science ®Google Scholar
• TangJKernTSInflammation in diabetic retinopathyProg Retin Eye Res201130534335821635964
   PubMed Web of Science ®Google Scholar
• JonasJBKamppeterBAHarderBVossmerbaeumerUSauderGSpandauUHIntravitreal triamcinolone acetonide for diabetic macular edema: a prospective, randomized studyJ Ocul Pharmacol Ther200622320020716808682
   PubMed Web of Science ®Google Scholar
• JonasJBIntravitreal triamcinolone acetonide: a change in a paradigmOphthalmic Res200638421824516763379
   PubMed Web of Science ®Google Scholar
• FolkmanJAngiogenesis and apoptosisSemin Cancer Biol200313215916712654259
   PubMed Web of Science ®Google Scholar
• NakanoTOharaOTeraokaHAritaHGlucocorticoids suppress group II phospholipase A2 production by blocking mRNA synthesis and post-transcriptional expressionJ Biol Chem19902652112745127482373711
   PubMed Web of Science ®Google Scholar
• LeopoldIHNonsteroidal and steroidal anti-inflammatory agentsSearsMTarkkanenASurgical Pharmacology of the EyeNew York, NYRaven Press198583133
   Google Scholar
• EdelmanJLLutzDCastroMRCorticosteroids inhibit VEGF-induced vascular leakage in a rabbit model of blood-retinal and blood aqueous barrier breakdownExp Eye Res20058024925815670803
   PubMed Web of Science ®Google Scholar
• FunatsuHYamashitaHNomaHMimuraTYamashitaTHoriSIncreased levels of vascular endothelial growth factor and interleukin-6 in the aqueous humor of diabetics with macular edemaAm J Ophthalmol2002133707711755841
   PubMed Web of Science ®Google Scholar
• CampochiaroPANguyenQDHafizGAqueous levels of fluocinolone acetonide after administration of fluocinolone acetonide inserts or fluocinolone acetonide implantsOphthalmology201312058358723218184
   PubMed Web of Science ®Google Scholar
• GilliesMCSutterFKSimpsonJMLarssonJAliHZhuMIntravitreal triamcinolone for refractory diabetic macular edema: two-year results of a doublemasked, placebo-controlled, randomized clinical trialOphthalmology20061131533153816828501
   PubMed Web of Science ®Google Scholar
• MartidisADukerJSGreenbergPBIntravitreal triamcinolone for refractory diabetic macular edemaOphthalmology200210992092711986098
   PubMed Web of Science ®Google Scholar
• BresslerNMEdwardsARBeckRWExploratory analysis of diabetic retinopathy progression through 3 years in a randomized clinical trial that compares intravitreal triamcinolone acetonide with focal/grid photocoagulationArch Ophthalmol20091271566157120008708
   PubMedGoogle Scholar
• Diabetic Retinopathy Clinical Research NetworkA randomized trial comparing intravitreal triamcinolone acetonide and focal/grid photocoagulation for diabetic macular edemaOphthalmology20081151447144918662829
   PubMed Web of Science ®Google Scholar
• CampochiaroPAHafizGShahSMFAMOUS Study GroupSustained ocular delivery of fluocinolone acetonide by an intravitreal insertOphthalmology20101171393139920202684
   PubMed Web of Science ®Google Scholar
• ILUVIEN^® [summary of product characteristics] Last updated on eMC 18-Feb-2014. Available from: https://www.medicines.org.uk/emc/medicine/27636Accessed July 24, 2014
   Google Scholar
• CampochiaroPABrownDMPearsonASustained delivery fluocinolone acetonide vitreous inserts provide benefit for at least 3 years in patients with diabetic macular edemaOphthalmology20121192125213222727177
   PubMed Web of Science ®Google Scholar
• Cunha-VazJAshtonPIezziRSustained delivery fluocinolone acetonide vitreous implantsOphthalmology20141211892190324935282
   PubMed Web of Science ®Google Scholar
• NeubauerASUlbigMWLaser treatment in diabetic retinopathyOphthalmologica20072219510217380063
   PubMed Web of Science ®Google Scholar
• NguyenQDShahSMKhwajaAATwo year outcomes of the ranibizumab for edema of the macula in diabetes (READ-2) studyOphthalmology20101172146215120855114
   PubMed Web of Science ®Google Scholar
• BresslerNMVarmaRSuñerIJVision-related function after ranibizumab treatment for diabetic macular edema: results from RIDE and RISEOphthalmology2014121122461247225148789
   PubMed Web of Science ®Google Scholar
• BrownDMNguyenQDMarcusDMLong-term outcomes of ranibizumab therapy for diabetic macular edema: the 36-month results from two phase III trials: RISE and RIDEOphthalmology20131202013202223706949
   PubMed Web of Science ®Google Scholar
• NguyenQDBrownDMMarcusDMRanibizumab for diabetic macular edema: results from 2 phase III randomized trials: RISE and RIDEOphthalmology2012119789801 Supplemental material (Table 6). Available from: http://www.aaojournal.org/cms/attachment/2005446053/2023774732/mmc1.pdfAccessed August 22, 201422330964
   PubMed Web of Science ®Google Scholar