Safety, efficacy, and clinical utility of asparaginase in the treatment of adult patients with acute lymphoblastic leukemia

References

• NachmanJClinical characteristics, biologic features and outcome for young adult patients with acute lymphoblastic leukaemiaBr J Haematol200513016617316029445
   PubMed Web of Science ®Google Scholar
• NachmanJBSatherHNSenselMGAugmented post-induction therapy for children with high-risk acute lymphoblastic leukemia and a slow response to initial therapyN Engl J Med1998338166316719614257
   PubMed Web of Science ®Google Scholar
• RoweJMBuckGBurnettAKInduction therapy for adults with acute lymphoblastic leukemia: results of more than 1500 patients from the international ALL trial: MRC UKALL XII/ECOG E2993Blood20051063760376716105981
   PubMed Web of Science ®Google Scholar
• KantarjianHThomasDO’BrienSLong-term follow-up results of hyperfractionated cyclophosphamide, vincristine, doxorubicin, and dexamethasone (Hyper-CVAD), a dose-intensive regimen, in adult acute lymphocytic leukemiaCancer2004101122788280115481055
   PubMed Web of Science ®Google Scholar
• GokbugetNHoelzerDArnoldRTreatment of adult ALL according to protocols of the German Multicenter Study Group for Adult ALL (GMALL)Hematol Oncol Clin North Am2000141307132511147225
   PubMed Web of Science ®Google Scholar
• AnninoLVegnaMLCameraATreatment of adult acute lym-phoblastic leukemia (ALL): long-term follow-up of the GIMEMA ALL 0288 randomized studyBlood20029986387111806988
   PubMed Web of Science ®Google Scholar
• CapizziRLBertinoJRSkeelRTl-asparaginase: clinical, biochemical, pharmacological, and immunological studiesAnn Intern Med1971748939015281051
   PubMed Web of Science ®Google Scholar
• HorowitzBMadrasBKMeisterAOldLJBoyesEAStockertEAsparagine synthetase activity of mouse leukemiasScience19681605335355689413
   PubMedGoogle Scholar
• HaskellCMCanellosGPl-asparaginase resistance in human leukemia–asparagine synthetaseBiochem Pharmacol196918257825804935103
   PubMed Web of Science ®Google Scholar
• KiriyamaYKubotaMTakimotoTBiochemical characterization of U937 cells resistant to l-asparaginase: the role of asparagine synthetaseLeukemia198932942972564453
   PubMed Web of Science ®Google Scholar
• AslanianAMFletcherBSKilbergMSAsparagine synthetase expression alone is sufficient to induce l-asparaginase resistance in MOLT-4 human leukaemia cellsBiochem J200135732132811415466
   PubMed Web of Science ®Google Scholar
• HutsonRGKitohTMoraga AmadorDACosicSSchusterSMKilbergMSAmino acid control of asparagine synthetase: relation to asparaginase resistance in human leukemia cellsAm J Physiol1997272C1691C16999176161
   PubMed Web of Science ®Google Scholar
• AsselinBLRyanDFrantzCNIn vitro and in vivo killing of acute lymphoblastic leukemia cells by l-asparaginaseCancer Res198949436343682743326
   PubMed Web of Science ®Google Scholar
• GrigoryanRSPanosyanEHSeibelNLGaynonPSAvramisIAAvramisVIChanges of amino acid serum levels in pediatric patients with higher-risk acute lymphoblastic leukemia (CCG-1961)In Vivo200418210711215113036
   PubMed Web of Science ®Google Scholar
• BoosJWerberGAhlkeEMonitoring of asparaginase activity and asparagine levels in children on different asparaginase preparationsEur J Cancer199632A9154415508911116
   PubMed Web of Science ®Google Scholar
• AvramisVISencerSPericlouAPA randomized comparison of native Escherichia coli asparaginase and polyethylene glycol conjugated asparaginase for treatment of children with newly diagnosed standard-risk acute lymphoblastic leukemia: a Children’s Cancer Group studyBlood20029961986199411877270
   PubMed Web of Science ®Google Scholar
• LenzHJManagement and preparedness for infusion and hypersensitivity reactionsOncologist200712560117522249
   PubMed Web of Science ®Google Scholar
• LiuCKawediaJDChengCClinical utility and implications of asparaginase antibodies in acute lymphoblastic leukemiaLeukemia201226112303230922484422
   PubMed Web of Science ®Google Scholar
• TongWHPietersRKaspersGJA prospective study on drug monitoring of PEGasparaginase and Erwinia asparaginase and aspara-ginase antibodies in pediatric acute lymphoblastic leukemiaBlood2014123132026203324449211
   PubMed Web of Science ®Google Scholar
• WangBRellingMVStormMCEvaluation of immunologic cross reaction of anti asparaginase antibodies in acute lymphoblastic leukemia (ALL) and lymphoma patientsLeukemia2003178158312886246
   PubMed Web of Science ®Google Scholar
• AvramisVISencerSPericlouAPA randomized comparison of native Escherichia coli asparaginase and polyethylene glycol conjugated asparaginase for treatment of children with newly diagnosed standard-risk acute lymphoblastic leukemia: a Children’s Cancer Group studyBlood2002996198611877270
   PubMed Web of Science ®Google Scholar
• AlbertsenBKSchrøderHJakobsenPAntibody formation during intravenous and intramuscular therapy with Erwinia asparaginaseMed Pediatr Oncol200238531011979454
   PubMedGoogle Scholar
• WooMHHakLJStormMCHypersensitivity or development of antibodies to asparaginase does not impact treatment outcome of childhood acute lymphoblastic leukemiaClin Oncol20001871525
   Google Scholar
• PanosyanEHSeibelNLMartin-AragonSAsparaginase antibody and asparaginase activity in children with higher-risk acute lymphoblastic leukemia: Children’s Cancer Group Study CCG-1961J Pediatr Hematol Oncol200426421715087948
   PubMed Web of Science ®Google Scholar
• CarusoVIacovielloLDi CastelnuovoAThrombotic complications in childhood acute lymphoblastic: a meta-analysis of 17 prospective studies comprising 1752 pediatric patientsBlood20061082216222216804111
   PubMed Web of Science ®Google Scholar
• ElliotMAWolfRCHookCCThromboembolism in adults with acute lymphoblastic leukemia during induction with l-asparaginase-containing multi-agent regimens: incidence, risk factors, and possible role of antithrombinLeuk Lymphoma2004451545154915370205
   PubMedGoogle Scholar
• GraceRFDahlbergSENeubergDThe frequency and management of asparaginase-related thrombosis in paediatric and adult patients with acute lymphoblastic leukaemia treated on Dana-Farber Cancer Institute consortium protocolsBr J Haematol201115245245921210774
   PubMed Web of Science ®Google Scholar
• MitchellLGAndrewMHannaKA prospective cohort study determining the prevalence of thrombotic events in children with acute lymphoblastic leukemia and a central venous line who are treated with l-asparaginase: results of the prophylactic antithrombin replacement in kids treated with acute lymphoblastic leukemia treated with aspara-ginase (PARKAA) studyCancer20039750851612518376
   PubMed Web of Science ®Google Scholar
• CouturierMAHuguetFChevallierPCerebral venous thrombosis in adult patients with acute lymphoblastic leukemia or lymphoblastic lymphoma during induction chemotherapy with l-asparaginase: The GRAALL experienceAm J Hematol2015901198699126214580
   PubMed Web of Science ®Google Scholar
• RantaSTuckuvieneRMäkiperaaACerebral sinus venous thromboses in children with acute lymphoblastic leukaemia – a mulitcentre study from the Nordic Society of Paediatric Haematology and OncologyBr J Haematol2015168454755225288392
   PubMedGoogle Scholar
• HoelzerDThielELöfflerHIntensified therapy in acute lym-phoblastic and acute undifferentiated leukemia in adultsBlood198464138476375764
   PubMed Web of Science ®Google Scholar
• DeAngeloDJStevensonKEDahlbergSELong-term outcome of a pediatric-inspired regimen used for adults aged 18–50 years with newly diagnosed acute lymphoblastic leukemiaLeukemia20152952653425079173
   PubMed Web of Science ®Google Scholar
• SilvermanLBGelberRDDaltonVKImproved outcome for children with acute lymphoblastic leukemia: results of Dana-Farber Consortium Protocol 91-01Blood20019751211121811222362
   PubMed Web of Science ®Google Scholar
• DouerDAldossILunningMAPharmacokinetics-based integration of multiple doses of intravenous pegaspargase in a pediatric regimen for adults with newly diagnosed acute lymphoblastic leukemiaJ Clin Oncol201432990591124516026
   PubMed Web of Science ®Google Scholar
• RijneveldAWvan der HoltBDaenenSMIntensified chemotherapy inspired by a pediatric regimen combined with allogeneic transplantation in adult patients with acute lymphoblastic leukemia up to the age of 40Leukemia201125111697170321647160
   PubMed Web of Science ®Google Scholar
• HuguetFLeguayTRaffouxEPediatric-inspired therapy in adults with Philadelphia chromosome-negative acute lymphoblastic leukemia: the GRAALL-2003 studyJ Clin Oncol200927691191819124805
   PubMed Web of Science ®Google Scholar
• StorringJMMindenMDKaoSTreatment of adults with BCR-ABL negative acute lymphoblastic leukaemia with a modified paediatric regimenBr J Haematol20091461768519438471
   PubMed Web of Science ®Google Scholar
• KadiaTMKantarjianHMThomasDAPhase II study of methotrexate, vincristine, pegylated-asparaginase, and dexamethasone (MOpAD) in patients with relapsed/refractory acute lymphoblastic leukemiaAm J Hematol201590212012425368968
   PubMed Web of Science ®Google Scholar
• DomenechCThomasXChabaudSl-asparaginase loaded red blood cells in refractory or relapsing acute lymphoblastic leukaemia in children and adults: results of the GRASPALL 2005-01 randomized trialBr J Haematol20111531586521332712
   PubMed Web of Science ®Google Scholar
• Hunault-BergerMLeguayTDombretHA Phase 2 study of l-asparaginase encapsulated in erythrocytes in elderly patients with Philadelphia chromosome negative acute lymphoblastic leukemia: The GRASPALL/GRAALL-SA2-2008 studyAm J Hematol201590981181826094614
   PubMed Web of Science ®Google Scholar