References
- American Cancer SocietyCancer Facts & Figures 2013 Available from: https://www.cancer.org/research/cancer-facts-statistics/all-cancer-facts-figures/cancer-facts-figures-2013.htmlAccessed February 8, 2017
- YuHKortylewskiMPardollDCrosstalk between cancer and immune cells: role of STAT3 in the tumour microenvironmentNat Rev Immunol200771415117186030
- MavaddatNAntoniouACEastonDFGarcia-ClosasMGenetic susceptibility to breast cancerMol Oncol20104317419120542480
- YuJCDingSLChangCHGenetic susceptibility to the development and progression of breast cancer associated with polymorphism of cell cycle and ubiquitin ligase genesCarcinogenesis20093091562157019587092
- de VisserKEEichtenACoussensLMParadoxical roles of the immune system during cancer developmentNat Rev Cancer200661243716397525
- YangCXLiCYFengWToll-like receptor 4 genetic variants and prognosis of breast cancerTissue Antigens201381422122623510418
- MaFJLiuZBHuXPrognostic value of myeloid differentiation primary response 88 and Toll-like receptor 4 in breast cancer patientsPLoS One2014910e11163925360699
- YangHWangBWangTToll-like receptor 4 prompts human breast cancer cells invasiveness via lipopolysaccharide stimulation and is overexpressed in patients with lymph node metastasisPLoS One2014910e10998025299052
- AhmedAWangJHRedmondHPSilencing of TLR4 increases tumor progression and lung metastasis in a murine model of breast cancerAnn Surg Oncol201320Suppl 3S389S39622890596
- BergmannCBachmannHSBankfalviAToll-like receptor 4 single-nucleotide polymorphisms Asp299Gly and Thr399Ile in head and neck squamous cell carcinomasJ Transl Med2011913921854645
- BhateliaKSinghKSinghRTLRs: linking inflammation and breast cancerCell Signal201426112350235725093807
- RodríguezNCKaakoushNKhean-LeeGMingFKMitchellHPattern recognition receptors in helicobacter pylori-related gastric cancerHelicobacter20141985
- BasithSManavalanBYooTHKimSGChoiSRoles of toll-like receptors in cancer: a double-edged sword for defense and offenseArch Pharm Res20123581297131622941474
- DrexlerSKFoxwellBMThe role of Toll-like receptors in chronic inflammationInt J Biochem Cell Biol201042450651819837184
- SchreibeltGTelJSliepenKHToll-like receptor expression and function in human dendritic cell subsets: implications for dendritic cell-based anti-cancer immunotherapyCancer Immunol Immunother201059101573158220204387
- Kurt-JonesEAPopovaLKwinnLPattern recognition receptors TLR4 and CD14 mediate response to respiratory syncytial virusNat Immunol20001539840111062499
- RassaJCMeyersJLZhangYKudaravalliRRossSRMurine retroviruses activate B cells via interaction with toll-like receptor 4Proc Natl Acad Sci U S A20029942281228611854525
- HuangBZhaoJLiHToll-like receptors on tumor cells facilitate evasion of immune surveillanceCancer Res200565125009501415958541
- MolteniMMarabellaDOrlandiCRossettiCMelanoma cell lines are responsive in vitro to lipopolysaccharide and express TLR-4Cancer Lett20062351758315922507
- RenTWenZKLiuZMLiangYJGuoZLXuLFunctional expression of TLR9 is associated to the metastatic potential of human lung cancer cell: functional active role of TLR9 on tumor metastasisCancer Biol Ther20076111704170917986857
- SzczepanskiMJCzystowskaMSzajnikMTriggering of Toll-like receptor 4 expressed on human head and neck squamous cell carcinoma promotes tumor development and protects the tumor from immune attackCancer Res20096973105311319318560
- de OliveiraJGSilvaAEPolymorphisms of the TLR2 and TLR4 genes are associated with risk of gastric cancer in a Brazilian populationWorld J Gastroenterol201218111235124222468087
- MilneANCarneiroFO’MorainCOfferhausGJNature meets nurture: molecular genetics of gastric cancerHum Genet2009126561562819657673
- Garza-GonzalezEBosques-PadillaFJMendoza-IbarraSIFlores-GutierrezJPMaldonado-GarzaHJPerez-PerezGIAssessment of the toll-like receptor 4 Asp299Gly, Thr399Ile and interleukin-8-25 I polymorphisms in the risk for the development of distal gastric cancerBMC Cancer200777017462092
- TaharaTArisawaTWangFToll-like receptor 2-196 to 174del polymorphism influences the susceptibility of Japanese people to gastric cancerCancer Sci200798111790179417711514
- SlatteryMLHerrickJSBondurantKLWolffRKToll-like receptor genes and their association with colon and rectal cancer development and prognosisInt J Cancer2012130122974298021792899
- AgúndezJAGarcía-MartínEDevesaMJPolymorphism of the TLR4 gene reduces the risk of hepatitis C virus-induced hepatocellular carcinomaOncology2012821354022286521
- StevensVLHsingAWTalbotJTGenetic variation in the toll-like receptor gene cluster (TLR10-TLR1-TLR6) and prostate cancer riskInt J Cancer2008123112644265018752252
- MandalRKGeorgeGPMittalRDAssociation of Toll-like receptor (TLR) 2, 3 and 9 genes polymorphism with prostate cancer risk in North Indian populationMol Biol Rep20123977263726922311043
- KimMKParkSWKimSKAssociation of Toll-like receptor 2 polymorphisms with papillary thyroid cancer and clinicopathologic features in a Korean populationJ Korean Med Sci201227111333133823166414
- PriyadarshiniAChakrabortiAMandalAKSinghSKAsp299Gly and Thr399Ile polymorphism of TLR-4 gene in patients with prostate cancer from North IndiaIndian J Urol2013291374123671363
- NiedzielskaINiedzielskiZTkaczMToll-like receptors and the tendency of normal mucous membrane to transform to polyp or colorectal cancerJ Physiol Pharmacol200960Suppl 16571
- AhmedARedmondHPWangJHLinks between Toll-like receptor 4 and breast cancerOncoimmunology201322e2294523526132
- ApetohLTesniereAGhiringhelliFKroemerGZitvogelLMolecular interactions between dying tumor cells and the innate immune system determine the efficacy of conventional anticancer therapiesCancer Res200868114026403018519658
- El-OmarEMNgMTHoldGLPolymorphisms in Toll-like receptor genes and risk of cancerOncogene200827224425218176606
- Barnholtz-SloanJSShettyPBGuanXFGFR2 and other loci identified in genome-wide association studies are associated with breast cancer in African-American and younger womenCarcinogenesis20103181417142320554749
- ParkerRLHuntsmanDGLesackDWAssessment of interlaboratory variation in the immunohistochemical determination of estrogen receptor status using a breast cancer tissue microarrayAm J Clin Pathol2002117572372812090420
- SemlaliAReddy ParineNArafahMExpression and polymorphism of Toll-like receptor 4 and effect on NF-κB mediated inflammation in colon cancer patientsPLoS One2016111e014633326771524
- AlanaziMPathanAAAbduljaleelZAssociation between PARP-1 V762A polymorphism and breast cancer susceptibility in Saudi populationPLoS One2013812e8554124392019
- YangHZhouHFengPReduced expression of Toll-like receptor 4 inhibits human breast cancer cells proliferation and inflammatory cytokines secretionJ Exp Clin Cancer Res2010299220618976
- RajputSVolk-DraperLDRanSTLR4 is a novel determinant of the response to paclitaxel in breast cancerMol Cancer Ther20131281676168723720768
- YuanXZhouYWangWActivation of TLR4 signaling promotes gastric cancer progression by inducing mitochondrial ROS productionCell Death Dis20134e79424030146
- TangXZhuYTLR4 signaling promotes immune escape of human colon cancer cells by inducing immunosuppressive cytokines and apoptosis resistanceOncol Res2012201152423035361
- KellyMGAlveroABChenRTLR-4 signaling promotes tumor growth and paclitaxel chemoresistance in ovarian cancerCancer Res20066673859386816585214
- EhsanNMuradSAshiqTSignificant correlation of TLR4 expression with the clinicopathological features of invasive ductal carcinoma of the breastTumour Biol20133421053105923338716
- WangJHManningBJWuQDBlanksonSBouchier-HayesDRedmondHPEndotoxin/lipopolysaccharide activates NF-kappa B and enhances tumor cell adhesion and invasion through a beta 1 integrin-dependent mechanismJ Immunol2003170279580412517943
- LiaoSJZhouYHYuanYTriggering of Toll-like receptor 4 on metastatic breast cancer cells promotes αvβ3-mediated adhesion and invasive migrationBreast Cancer Res Treat2012133385386322042369
- ReslerAJMaloneKEJohnsonLGGenetic variation in TLR or NFkappaB pathways and the risk of breast cancer: a case-control studyBMC Cancer20131321923634849
- MarinoMXenoestrogens challenge 17β-estradiol protective effects in colon cancerWorld J Gastrointest Oncol201463677324653796
- BarziALenzAMLabonteMJLenzHJMolecular pathways: estrogen pathway in colorectal cancerClin Cancer Res201319215842584823965904
- al-AzzawiFWahabMEstrogen and colon cancer: current issuesClimacteric20025131411974557
- HendrickseCWJonesCEDonovanIANeoptolemosJPBakerPROestrogen and progesterone receptors in colorectal cancer and human colonic cancer cell linesBr J Surg19938056366408518910
- ChenYCGiovannucciELazarusRKraftPKetkarSHunterDJSequence variants of Toll-like receptor 4 and susceptibility to prostate cancerCancer Res20056524117711177816357190
- SantiniDAngelettiSRuzzoAToll-like receptor 4 Asp299Gly and Thr399Ile polymorphisms in gastric cancer of intestinal and diffuse histotypesClin Exp Immunol2008154336036418826495
- OhtoUYamakawaNAkashi-TakamuraSMiyakeKShimizuTStructural analyses of human Toll-like receptor 4 polymorphisms D299G and T399IJ Biol Chem201228748406114061723055527
- FigueroaLXiongYSongCPiaoWVogelSNMedvedevAThe Asp299Gly polymorphism alters TLR4 signaling by interfering with recruitment of adapter proteins MyD88 and TRIFJ Immunol201218894506451522474023