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Original Research

Polydatin regulates proliferation, apoptosis and autophagy in multiple myeloma cells through mTOR/p70s6k pathway

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Pages 935-944 | Published online: 16 Feb 2017

References

  • StewartAKFonsecaRPrognostic and therapeutic significance of myeloma genetics and gene expression profilingJ Clin Oncol200523266339634416155017
  • MunshiNCAndersonKCBergsagelPLInternational Myeloma Workshop Consensus Panel 2Consensus recommendations for risk stratification in multiple myeloma: report of the International Myeloma Workshop Consensus Panel 2Blood2011117184696470021292777
  • CuendetMChristovKLantvitDDMultiple myeloma regression mediated by bruceantinClin Cancer Res20041031170117914871997
  • SantMAllemaniCTereanuCIncidence of hematological malignancies in Europe by morphological subtype: results of the HAEMACARE projectBlood2010116193724373420664057
  • MatsumotoTJimiSMigitaKTakamatsuYHaraSInhibition of glucose transporter 1 induces apoptosis and sensitizes multiple myeloma cells to conventional chemotherapeutic agentsLeuk Res20164110311026790725
  • ZhaoKSJinCHuangXThe mechanism of polydatin in shock treatmentClin Hemorheol Microcirc2003293–421121714724344
  • ZhaoKSHemorheologic events in severe shockBiorheology200542646347716369084
  • WangXSongRChenYZhaoMZhaoKSPolydatin – a new mitochondria protector for acute severe hemorrhagic shock treatmentExpert Opin Investig Drugs2013222169179
  • ChengYZhangHTSunLInvolvement of cell adhesion molecules in polydatin protection of brain tissues from ischemia-reperfusion injuryBrain Res20061110119320016870162
  • WangCLuoYLuJWangYShengGPolydatin induces apoptosis and inhibits growth of acute monocytic leukemia cellsJ Biochem Mol Toxicol201630420020526616494
  • XuGKuangGJiangWJiangRJiangDPolydatin promotes apoptosis through upregulation the ratio of Bax/Bcl-2 and inhibits proliferation by attenuating the β-catenin signaling in human osteosarcoma cellsAm J Transl Res20168292293127158379
  • ZhangYZhuangZMengQJiaoYXuJFanSPolydatin inhibits growth of lung cancer cells by inducing apoptosis and causing cell cycle arrestOncol Lett20147129530124348867
  • StrimpakosASKarapanagiotouEMSaifMWSyrigosKNThe role of mTOR in the management of solid tumors: an overviewCancer Treat Rev200935214815919013721
  • LeeDFKuoHPChenCTIKK beta suppression of TSC1 links inflammation and tumor angiogenesis via the mTOR pathwayCell2007130344045517693255
  • LiuLZZhengJZWangXRJiangBHEndothelial p70 S6 kinase 1 in regulating tumor angiogenesisCancer Res200868198183818818829578
  • LevineBKroemerGAutophagy in the pathogenesis of diseaseCell20081321274218191218
  • BaldoPCeccoSGiacominELazzariniRRosBMarastoniSmTOR pathway and mTOR inhibitors as agents for cancer therapyCurr Cancer Drug Targets20088864766519075588
  • HayNThe Akt-mTOR tango and its relevance to cancerCancer Cell20058317918316169463
  • InokiKCorradettiMNGuanKLDysregulation of the TSC-mTOR pathway in human diseaseNat Genet2005371192415624019
  • PangXYiZZhangJCelastrol suppresses angiogenesis-mediated tumor growth through inhibition of AKT/mammalian target of rapamycin pathwayCancer Res20107051951195920160026
  • NetoCCAmorosoJWLibertyAMAnticancer activities of cranberry phytochemicals: an updateMol Nutr Food Res200852Suppl 1S18S2718504707
  • KaurMAgarwalRTranscription factors: molecular targets for prostate cancer intervention by phytochemicalsCurr Cancer Drug Targets20077435536717979630
  • FanTFWuTFBuLLDihydromyricetin promotes autophagy and apoptosis through ROS-STAT3 signaling in head and neck squamous cell carcinomaOncotarget2016737596915970327474168
  • YeTZhuSZhuYCryptotanshinone induces melanoma cancer cells apoptosis via ROS-mitochondrial apoptotic pathway and impairs cell migration and invasionBiomed Pharmacother20168231932627470369
  • YueHLiWLiuPGaoJMiaoJZhaoJInhibition of autophagy promoted sphingosylphosphorylcholine induced cell death in non-small cell lung cancer cellsBiochem Biophys Res Commun2014453350250725285628
  • KomatsuMWaguriSChibaTLoss of autophagy in the central nervous system causes neurodegeneration in miceNature2006441709588088416625205
  • ZhangLWangHZhuJXuJDingKMollugin induces tumor cell apoptosis and autophagy via the PI3K/AKT/mTOR/p70S6K and ERK signaling pathwaysBiochem Biophys Res Commun2014450124725424887566
  • LuoCLLiuYQWangPThe effect of quercetin nanoparticle on cervical cancer progression by inducing apoptosis, autophagy and anti-proliferation via JAK2 suppressionBiomed Pharmacother20168259560527470402
  • ZhaoZQYuZYLiJOuyangXNGefitinib induces lung cancer cell autophagy and apoptosis via blockade of the PI3K/AKT/mTOR pathwayOncol Lett2016121636827347100
  • CaoZXYangYTYuSPogostone induces autophagy and apoptosis involving PI3K/Akt/mTOR axis in human colorectal carcinoma HCT116 cellsJ Ethnopharmacol2016piiS0378S8741163045330456
  • BordersEBBivonaCMedinaPJMammalian target of rapamycin: biological function and target for novel anticancer agentsAm J Health Syst Pharm201067242095210621116000
  • YapTAGarrettMDWaltonMIRaynaudFde BonoJSWorkmanPTargeting the PI3K-AKT-mTOR pathway: progress, pitfalls, and promisesCurr Opin Pharmacol20088439341218721898