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Original Research

Novel role of granulocyte-macrophage colony-stimulating factor: antitumor effects through inhibition of epithelial-to-mesenchymal transition in esophageal cancer

, , , , , , , & show all
Pages 2227-2237 | Published online: 20 Apr 2017

References

  • TorreLABrayFSiegelRLFerlayJLortet-TieulentJJemalAGlobal cancer statistics, 2012CA Cancer J Clin20156528710825651787
  • ChenWZhengRBaadePDCancer statistics in China, 2015CA Cancer J Clin201666211513226808342
  • SankaranarayananRSwaminathanRJayantKBrennerHAn overview of cancer survival in Africa, Asia, the Caribbean and Central America: the case for investment in cancer health servicesIARC Sci Publ201116225729121675431
  • MetcalfDHematopoietic cytokinesBlood2008111248549118182579
  • McLeishKRKnallCWardRAActivation of mitogen-activated protein kinase cascades during priming of human neutrophils by TNF-alpha and GM-CSFJ Leukoc Biol19986445375459766635
  • MetcalfDThe colony-stimulating factors and cancerNat Rev Cancer201010642543420495576
  • VilaltaMRafatMGiacciaAJGravesEERecruitment of circulating breast cancer cells is stimulated by radiotherapyCell Rep20148240240925017065
  • ParkBKZhangHZengQNF-kappaB in breast cancer cells promotes osteolytic bone metastasis by inducing osteoclastogenesis via GM-CSFNat Med2007131626917159986
  • AliperAMFrieden-KorovkinaVPBuzdinARoumiantsevSAZhavoronkovAA role for G-CSF and GM-CSF in nonmyeloid cancersCancer Med20143473774624692240
  • ChenDSMellmanIOncology meets immunology: the cancer-immunity cycleImmunity201339111023890059
  • van de LaarLCofferPJWoltmanAMRegulation of dendritic cell development by GM-CSF: molecular control and implications for immune homeostasis and therapyBlood2012119153383339322323450
  • ChenCHouJLinZA bystander cell-based GM-CSF secreting vaccine synergized with a low dose of cyclophosphamide presents therapeutic immune responses against murine hepatocellular carcinomaCell Mol Immunol201310434935923686226
  • ChenGGuptaRPetrikSA feasibility study of cyclophosphamide, trastuzumab, and an allogeneic GM-CSF-secreting breast tumor vaccine for HER2+ metastatic breast cancerCancer Immunol Res201421094996125116755
  • GuptaREmensLAGM-CSF-secreting vaccines for solid tumors: moving forwardDiscov Med20101050526020670599
  • SeledtsovVIGoncharovAGSeledtsovaGVClinically feasible approaches to potentiating cancer cell-based immunotherapiesHum Vaccin Immunother201511485186925933181
  • SavagnerPThe epithelial-mesenchymal transition (EMT) phenomenonAnn Oncol201021Suppl 7vii89vii9220943648
  • ChouYSYangMHEpithelial-mesenchymal transition-related factors in solid tumor and hematological malignancyJ Chin Med Assoc201578843844526078096
  • LiangNSongXXieJEffect of galectin-3 on the behavior of Eca109 human esophageal cancer cellsMol Med Rep201511289690225373317
  • EdgeSBComptonCCThe American Joint Committee on Cancer: the 7th edition of the AJCC cancer staging manual and the future of TNMAnn Surg Oncol20101761471147420180029
  • PfafflMWA new mathematical model for relative quantification in real-time RT-PCRNucleic Acids Res2001299e4511328886
  • StosserSSchweizerhofMKunerRHematopoietic colony-stimulating factors: new players in tumor-nerve interactionsMol Med (Berl)2011894321329
  • DengGHuPZhangJElevated serum granulocyte-macrophage colony-stimulating factor levels during radiotherapy predict favorable outcomes in lung and esophageal cancerOncotarget2016751851428515027835886
  • UrdinguioRGFernandezAFMoncada-PazosAImmune-dependent and independent antitumor activity of GM-CSF aberrantly expressed by mouse and human colorectal tumorsCancer Res201373139540523108143
  • BayneLJBeattyGLJhalaNTumor-derived granulocyte-macrophage colony-stimulating factor regulates myeloid inflammation and T cell immunity in pancreatic cancerCancer Cell201221682283522698406
  • ChaubeyNGhoshSSOverexpression of granulocyte macrophage colony stimulating factor in breast cancer cells leads towards drug sensitizationAppl Biochem Biotech2015175419481959
  • GoldenEBChhabraAChachouaALocal radiotherapy and granulocyte-macrophage colony-stimulating factor to generate abscopal responses in patients with metastatic solid tumours: a proof-of-principle trialLancet Oncol201516779580326095785
  • LawsonDHLeeSZhaoFRandomized, placebo-controlled, phase III trial of yeast-derived granulocyte-macrophage colony- stimulating factor (GM-CSF) versus peptide vaccination versus GM-CSF plus peptide vaccination versus placebo in patients with no evidence of disease after complete surgical resection of locally advanced and/or stage IV melanoma: A trial of the Eastern Cooperative Oncology Group-American College of Radiology Imaging Network Cancer Research Group (E4697)Clin Oncol2015333440664076
  • ChenHHSuWCChouCYIncreased expression of nitric oxide synthase and cyclooxygenase-2 is associated with poor survival in cervical cancer treated with radiotherapyInt J Radiat Oncol Biol Phys20056341093110016099602
  • LicinioJProloPMcCannSMWongMLBrain iNOS: current understanding and clinical implicationsMol Med Today19995522523210322315
  • SanghiSMacLaughlinEJJewellCWCyclooxygenase-2 inhibitors: a painful lessonCardiovasc Hematol Disord Drug Targets2006628510016787194
  • SarianLODerchainSFYoshidaAVassalloJPignataroFDe Angelo AndradeLAExpression of cyclooxygenase-2 (COX-2) and Ki67 as related to disease severity and HPV detection in squamous lesions of the cervixGynecol Oncol2006102353754116537091
  • WatanabeKKawamoriTNakatsugiSWakabayashiKCOX-2 and iNOS, good targets for chemoprevention of colon cancerBiofactors2000121–412913311216473
  • SaldivarJSLopezDFeldmanRACOX-2 overexpression as a biomarker of early cervical carcinogenesis: a pilot studyGynecol Oncol20071071 Suppl 1S155S16217826825
  • JiangNTianZTangJOuRXuYGranulocyte-macrophage colony-stimulating factor (GM-CSF) downregulates the expression of protumor factors cyclooxygenase-2 and inducible nitric oxide synthase in a GM-CSF receptor-independent manner in cervical cancer cellsMediators Inflamm2015201560160426257474
  • CondamineTGabrilovichDIMolecular mechanisms regulating myeloid-derived suppressor cell differentiation and functionTrends Immunol2011321192521067974
  • CruzMTDuarteCBGoncaloMFigueiredoACarvalhoAPLopesMCGranulocyte-macrophage colony-stimulating factor activates the transcription of nuclear factor kappa B and induces the expression of nitric oxide synthase in a skin dendritic cell lineImmunol Cell Biol200179659059611903618
  • BurlacuARegulation of apoptosis by Bcl-2 family proteinsJ Cell Mol Med20037324925714594549
  • CoccoCCanaleSFrassonCInterleukin-23 acts as antitumor agent on childhood B-acute lymphoblastic leukemia cellsBlood2010116193887389820671120
  • SubramanianMThorpETabasIIdentification of a non-growth factor role for GM-CSF in advanced atherosclerosis: promotion of macrophage apoptosis and plaque necrosis through IL-23 signalingCirc Res20151162e13e2425348165
  • HuangXChoiJKParkSRGM-CSF inhibits apoptosis of neural cells via regulating the expression of apoptosis-related proteinsNeurosci Res2007581505717331604
  • KleinJBRaneMJScherzerJAGranulocyte-macrophage colony-stimulating factor delays neutrophil constitutive apoptosis through phosphoinositide 3-kinase and extracellular signal-regulated kinase pathwaysJ Immunol200016484286429110754327
  • Kotone-MiyaharaYYamashitaKLeeKKShort-term delay of Fas-stimulated apoptosis by GM-CSF as a result of temporary suppression of FADD recruitment in neutrophils: evidence implicating phosphatidylinositol 3-kinase and MEK1-ERK1/2 pathways downstream of classical protein kinase CJ Leukoc Biol20047651047105615328334
  • KamigakiMHideIYanaseYThe Toll-like receptor 4-activated neuroprotective microglia subpopulation survives via granulocyte macrophage colony-stimulating factor and JAK2/STAT5 signalingNeurochem Int201693829426802935
  • LiuFZhaoXPernaFJAK2V617F-mediated phosphorylation of PRMT5 downregulates its methyltransferase activity and promotes myeloproliferationCancer Cell201119228329421316606
  • StopaNKrebsJEShechterDThe PRMT5 arginine methyltransferase: many roles in development, cancer and beyondCell Mol Life Sci201572112041205925662273
  • IbrahimRMatsubaraDOsmanWExpression of PRMT5 in lung adenocarcinoma and its significance in epithelial-mesenchymal transitionHum Pathol20144571397140524775604
  • HouZPengHAyyanathanKThe LIM protein AJUBA recruits protein arginine methyltransferase 5 to mediate SNAIL-dependent transcriptional repressionMol Cell Biol200828103198320718347060