References
- EggerGLiangGAparicioAJonesPAEpigenetics in human disease and prospects for epigenetic therapyNature2004429699045746315164071
- Iacobuzio-DonahueCAEpigenetic changes in cancerAnnu Rev Pathol2009422924918840073
- HasslerMREggerGEpigenomics of cancer–emerging new conceptsBiochimie201294112219223022609632
- EstellerMCancer epigenomics: DNA methylomes and histone-modification mapsNat Rev Genet20078428629817339880
- BiancottoCFrigèGMinucciSHistone modification therapy of cancerAdv Genet20107034138620920755
- ShiYWhetstineJRDynamic regulation of histone lysine methylation by demethylasesMol Cell200725111417218267
- TzatsosAPfauRKampranisSCTsichlisPNNdy1/KDM2B immor-talizes mouse embryonic fibroblasts by repressing the Ink4a/Arf locusProc Natl Acad Sci U S A200910682641264619202064
- KottakisFFoltopoulouPSanidasINDY1/KDM2B functions as a master regulator of polycomb complexes and controls self-renewal of breast cancer stem cellsCancer Res201474143935394624853546
- PfauRTzatsosAKampranisSCSerebrennikovaOBBearSETsichlisPNMembers of a family of JmjC domain-containing oncoproteins immortalize embryonic fibroblasts via a JmjC domain-dependent processProc Natl Acad Sci U S A200810561907191218250326
- YuXWangJWuJShiYA systematic study of the cellular metabolic regulation of Jhdm1b in tumor cellsMol Biosyst20151171867187525877602
- RenYWuLLiXLiWYangYZhangMFBXL10 contributes to the progression of nasopharyngeal carcinoma via involving in PI3K/mTOR pathwayNeoplasma201562692593126458315
- YamaguchiHHungMCRegulation and role of EZH2 in cancerCancer Res Treat201446320922225038756
- JiaNLiQTaoXWangJHuaKFengWEnhancer of zeste homolog 2 is involved in the proliferation of endometrial carcinomaOncol Lett2014852049205425295088
- ZhangQPadiSKTindallDJGuoBPolycomb protein EZH2 suppresses apoptosis by silencing the proapoptotic miR-31Cell Death Dis20145e148625341040
- LinCHuangFLiQZZhangYJmiR-101 suppresses tumor proliferation and migration, and induces apoptosis by targeting EZH2 in esophageal cancer cellsInt J Clin Exp Pathol20147106543655025400732
- DebebBGGongYAtkinsonRLEZH2 expression correlates with locoregional recurrence after radiation in inflammatory breast cancerJ Exp Clin Cancer Res20143315825051981
- GaripovALiHBitlerBGThapaRJBalachandranSZhangRNF-YA underlies EZH2 upregulation and is essential for proliferation of human epithelial ovarian cancer cellsMol Cancer Res201311436036923360797
- GuoJCaiJYuLTangHChenCWangZEZH2 regulates expression of p57 and contributes to progression of ovarian cancer in vitro and in vivoCancer Sci2011102353053921205084
- KaroopongseEYeungCByonJThe KDM2B-let-7b -EZH2 axis in myelodysplastic syndromes as a target for combined epigenetic therapyPLoS One201499e10781725225797
- ZhangFXuLXuLJMJD3 promotes chondrocyte proliferation and hypertrophy during endochondral bone formation in miceJ Mol Cell Biol201571233425587042
- HaagTHerktCEWaleschSKRichterAMDammannRHThe apoptosis associated tyrosine kinase gene is frequently hypermethylated in human cancer and is regulated by epigenetic mechanismsGenes Cancer201459–1036537425352953
- HasemannMSLauridsenFKWaageJC/EBPα is required for long-term self-renewal and lineage priming of hematopoietic stem cells and for the maintenance of epigenetic configurations in multipotent progenitorsPLoS Genet2014101e100407924415956
- ZhangYWZhengYWangJZIntegrated analysis of DNA methylation and mRNA expression profiling reveals candidate genes associated with cisplatin resistance in non-small cell lung cancerEpigenetics20149689690924699858
- VillalbaMDiaz-LagaresARedradoMEpigenetic alterations leading to TMPRSS4 promoter hypomethylation and protein over-expression predict poor prognosis in squamous lung cancer patientsOncotarget2016716227522276926989022
- HongXXuYQiuXMiR-448 promotes glycolytic metabolism of gastric cancer by downregulating KDM2BOncotarget2016716220922210226989077
- ZehentmayrFHauser-KronbergerCZellingerBHsa-miR-375 is a predictor of local control in early stage breast cancerClin Epigenetics201682826962366
- Ayala-OrtegaEArzate-MejíaRPérez-MolinaREpigenetic silencing of miR-181c by DNA methylation in glioblastoma cell linesBMC Cancer20161622626983574
- PolytarchouCPfauRHatziapostolouMTsichlisPNThe JmjC domain histone demethylase Ndy1 regulates redox homeostasis and protects cells from oxidative stressMol Cell Biol200828247451746418838535
- KaviHHBirchlerJADrosophila KDM2 is a H3K4me3 demethylase regulating nucleolar organizationBMC Res Notes2009221719852816
- InagakiTIwasakiSMatsumuraYThe FBXL10/KDM2B scaffolding protein associates with novel polycomb repressive complex-1 to regulate adipogenesisJ Biol Chem201529074163417725533466
- SalminenAKaarnirantaKKauppinenAHypoxia-inducible histone lysine demethylases: impact on the aging process and age-related diseasesAging Dis20167218020027114850
- UedaTNagamachiATakuboKFbxl10 overexpression in murine hematopoietic stem cells induces leukemia involving metabolic activation and upregulation of Nsg2Blood2015125223437344625872778
- TzatsosAPaskalevaPFerrariFKDM2B promotes pancreatic cancer via Polycomb-dependent and -independent transcriptional programsJ Clin Invest2013123272773923321669
- FrescasDGuardavaccaroDBassermannFKoyama-NasuRPaganoMJHDM1B/FBXL10 is a nucleolar protein that represses transcription of ribosomal RNA genesNature2007450716730931317994099
- ChinaranagariSSharmaPChaudharyJEZH2 dependent H3K27me3 is involved in epigenetic silencing of ID4 in prostate cancerOncotarget20145167172718225115397
- GuoSLiXRohrJEZH2 overexpression in different immunophenotypes of breast carcinoma and association with clinicopathologic featuresDiagn Pathol20161114127113214
- ChenQZhengPSYangWTEZH2-mediated repression of GSK-3β and TP53 promotes Wnt/β-catenin signaling-dependent cell expansion in cervical carcinomaOncotarget2016724361153612927092879
- HanTJiaoFHuHEZH2 promotes cell migration and invasion but not alters cell proliferation by suppressing E-cadherin, partly through association with MALAT-1 in pancreatic cancerOncotarget2016710111941120726848980
- ChenWMHuangMDSunDPLong intergenic non-coding RNA 00152 promotes tumor cell cycle progression by binding to EZH2 and repressing p15 and p21 in gastric cancerOncotarget2016799773978726799422
- ZhangQZhaoWYeCHonokiol inhibits bladder tumor growth by suppressing EZH2/miR-143 axisOncotarget2015635373353734826484567
- MaDNChaiZTZhuXDMicroRNA-26a suppresses epithelial-mesenchymal transition in human hepatocellular carcinoma by repressing enhancer of zeste homolog 2J Hematol Oncol20169126733151
- YangCCLaBaffAWeiYPhosphorylation of EZH2 at T416 by CDK2 contributes to the malignancy of triple negative breast cancersAm J Transl Res2015761009102026279746
- TzatsosAPaskalevaPLymperiSLysine-specific demethylase 2B (KDM2B)-let-7-enhancer of zester homolog 2 (EZH2) pathway regulates cell cycle progression and senescence in primary cellsJ Biol Chem201128638330613306921757686