The role of desmosomes in carcinogenesis

References

• HolthoferBWindofferRTroyanovskySLeubeREStructure and function of desmosomesInt Rev Cytol20072646516317964922
   PubMedGoogle Scholar
• DusekRLAttardiLDDesmosomes: new perpetrators in tumour suppressionNat Rev Cancer201111531732321508970
   PubMed Web of Science ®Google Scholar
• GetsiosSHuenACGreenKJWorking out the strength and flexibility of desmosomesNat Rev Mol Cell Biol20045427128115071552
   PubMedGoogle Scholar
• KowalczykAPGreenKJStructure, function, and regulation of desmosomesProg Mol Biol Transl Sci20131169511823481192
   PubMed Web of Science ®Google Scholar
• BrookeMANitoiuDKelsellDPCell-cell connectivity: desmosomes and diseaseJ Pathol2012226215817121989576
   PubMedGoogle Scholar
• GarrodDChidgeyMDesmosome structure, composition and functionBiochim Biophys Acta20081778357258717854763
   PubMed Web of Science ®Google Scholar
• JohnsonJLKoetsierJLSiricoAThe desmosomal protein desmoglein 1 aids recovery of epidermal differentiation after acute UV light exposureJ Invest Dermatol201413482154216224594668
   PubMedGoogle Scholar
• CollinsJELeganPKKennyTPMacGarvieJHoltonJLGarrodDRCloning and sequence analysis of desmosomal glycoproteins 2 and 3 (desmocollins): cadherin-like desmosomal adhesion molecules with heterogeneous cytoplasmic domainsJ Cell Biol199111323813912010468
   PubMedGoogle Scholar
• ParkerAEWheelerGNArnemannJDesmosomal glycoproteins II and III. Cadherin-like junctional molecules generated by alternative splicingJ Biol Chem19912661610438104452037591
   PubMedGoogle Scholar
• CuiTChenYYangLDSC3 expression is regulated by p53, and methylation of DSC3 DNA is a prognostic marker in human colorectal cancerBr J Cancer201110461013101921364582
   PubMed Web of Science ®Google Scholar
• HatzfeldMThe p120 family of cell adhesion moleculesEur J Cell Biol2005842–320521415819401
   PubMedGoogle Scholar
• PeiferMMcCreaPDGreenKJWieschausEGumbinerBMThe vertebrate adhesive junction proteins beta-catenin and plakoglobin and the Drosophila segment polarity gene armadillo form a multigene family with similar propertiesJ Cell Biol199211836816911639851
   PubMedGoogle Scholar
• ChoiHJWeisWIStructure of the armadillo repeat domain of plakophilin 1J Mol Biol2005346136737615663951
   PubMedGoogle Scholar
• MertensCKuhnCFrankeWWPlakophilins 2a and 2b: constitutive proteins of dual location in the karyoplasm and the desmosomal plaqueJ Cell Biol19961354100910258922383
   PubMedGoogle Scholar
• SchmidtALangbeinLRodeMPratzelSZimbelmannRFrankeWWPlakophilins 1a and 1b: widespread nuclear proteins recruited in specific epithelial cells as desmosomal plaque componentsCell Tissue Res199729034814999369526
   PubMedGoogle Scholar
• SmithEAFuchsEDefining the interactions between intermediate filaments and desmosomesJ Cell Biol19981415122912419606214
   PubMedGoogle Scholar
• GreenKJParryDASteinertPMStructure of the human desmoplakins. Implications for function in the desmosomal plaqueJ Biol Chem19902651911406114072391353
   PubMedGoogle Scholar
• Al-JassarCBikkerHOverduinMChidgeyMMechanistic basis of desmosome-targeted diseasesJ Mol Biol2013425214006402223911551
   PubMedGoogle Scholar
• McGrathJAMcMillanJRShemankoCSMutations in the plakophilin 1 gene result in ectodermal dysplasia/skin fragility syndromeNat Genet19971722402449326952
   PubMedGoogle Scholar
• BroussardJAGetsiosSGreenKJDesmosome regulation and signaling in diseaseCell Tissue Res2015360350151225693896
   PubMedGoogle Scholar
• TselepisCChidgeyMNorthAGarrodDDesmosomal adhesion inhibits invasive behaviorProc Natl Acad Sci U S A19989514806480699653140
   PubMedGoogle Scholar
• ChidgeyMDawsonCDesmosomes: a role in cancer?Br J Cancer200796121783178717519903
   PubMedGoogle Scholar
• KurzenHMunzingIHartschuhWExpression of desmosomal proteins in squamous cell carcinomas of the skinJ Cutan Pathol2003301062163014744087
   PubMed Web of Science ®Google Scholar
• CaiFZhuQMiaoYShenSSuXShiYDesmoglein-2 is over-expressed in non-small cell lung cancer tissues and its knockdown suppresses NSCLC growth by regulation of p27 and CDK2J Cancer Res Clin Oncol20171431596927629878
   PubMedGoogle Scholar
• ChenYJChangJTLeeLDSG3 is overexpressed in head neck cancer and is a potential molecular target for inhibition of oncogenesisOncogene200726346747616878157
   PubMedGoogle Scholar
• FurukawaCDaigoYIshikawaNPlakophilin 3 oncogene as prognostic marker and therapeutic target for lung cancerCancer Res200565167102711016103059
   PubMed Web of Science ®Google Scholar
• BrownLWaseemACruzINDesmoglein 3 promotes cancer cell migration and invasion by regulating activator protein 1 and protein kinase C-dependent-Ezrin activationOncogene201433182363237423752190
   PubMedGoogle Scholar
• KolegraffKNavaPHelmsMNParkosCANusratALoss of desmocollin-2 confers a tumorigenic phenotype to colonic epithelial cells through activation of Akt/beta-catenin signalingMol Biol Cell20112281121113421325624
   PubMedGoogle Scholar
• ChenJO’SheaCFitzpatrickJEKosterMIKochPJLoss of desmocollin 3 in skin tumor development and progressionMol Carcinog201251753554521681825
   PubMedGoogle Scholar
• CuiTChenYYangLThe p53 target gene desmocollin 3 acts as a novel tumor suppressor through inhibiting EGFR/ERK pathway in human lung cancerCarcinogenesis201233122326233322941060
   PubMed Web of Science ®Google Scholar
• OshiroMMKimCJWozniakRJEpigenetic silencing of DSC3 is a common event in human breast cancerBreast Cancer Res200575R669R68016168112
   PubMed Web of Science ®Google Scholar
• CuiTChenYYangLDiagnostic and prognostic impact of desmocollins in human lung cancerJ Clin Pathol201265121100110623002285
   PubMedGoogle Scholar
• LiTWTingJHYokoyamaNNBernsteinAvan de WeteringMWatermanMLWnt activation and alternative promoter repression of LEF1 in colon cancerMol Cell Biol200626145284529916809766
   PubMed Web of Science ®Google Scholar
• MacDonaldBTTamaiKHeXWnt/beta-catenin signaling: components, mechanisms, and diseasesDev Cell200917192619619488
   PubMed Web of Science ®Google Scholar
• MiravetSPiedraJMiroFItarteEGarcia de HerrerosADunachMThe transcriptional factor Tcf-4 contains different binding sites for beta-catenin and plakoglobinJ Biol Chem200227731884189111711551
   PubMedGoogle Scholar
• AlaeeMDaneshGPasdarMPlakoglobin reduces the in vitro growth, migration and invasion of ovarian cancer cells expressing N-cadherin and mutant p53PLoS One2016115e015432327144941
   PubMedGoogle Scholar
• SechlerMBorowiczSVan ScoykMNovel role for gamma-catenin in the regulation of cancer cell migration via the induction of hepatocyte growth factor activator inhibitor type 1 (HAI-1)J Biol Chem201529025156101562025925948
   PubMedGoogle Scholar
• FangWKLiaoLDLiLYDown-regulated desmocollin-2 promotes cell aggressiveness through redistributing adherens junctions and activating beta-catenin signalling in oesophageal squamous cell carcinomaJ Pathol2013231225727023836524
   PubMedGoogle Scholar
• Bass-ZubekAEHobbsRPAmargoEVPlakophilin 2: a critical scaffold for PKC alpha that regulates intercellular junction assemblyJ Cell Biol2008181460561318474624
   PubMedGoogle Scholar
• Schmitt-GraeffAKoeningerAOlschewskiMThe Ki67+ proliferation index correlates with increased cellular retinol-binding protein-1 and the coordinated loss of plakophilin-1 and desmoplakin during progression of cervical squamous lesionsHistopathology2007511879717593084
   PubMedGoogle Scholar
• SchwarzJAyimASchmidtADifferential expression of desmosomal plakophilins in various types of carcinomas: correlation with cell type and differentiationHum Pathol200637561362216647960
   PubMedGoogle Scholar
• Sobolik-DelmaireTReddyRPashajARobertsBJWahlJK3rdPlakophilin-1 localizes to the nucleus and interacts with single-stranded DNAJ Invest Dermatol2010130112638264620613778
   PubMedGoogle Scholar
• AignerKDescovichLMikulaMThe transcription factor ZEB1 (deltaEF1) represses Plakophilin 3 during human cancer progressionFEBS Lett200758181617162417391671
   PubMedGoogle Scholar
• VillaretDBWangTDillonDIdentification of genes overexpressed in head and neck squamous cell carcinoma using a combination of complementary DNA subtraction and microarray analysisLaryn-goscope20001103 pt 1374381
   PubMedGoogle Scholar
• CheungIYFengYDanisKNovel markers of subclinical disease for Ewing family tumors from gene expression profilingClin Cancer Res200713236978698318056173
   PubMedGoogle Scholar
• AngstBDNillesLAGreenKJDesmoplakin II expression is not restricted to stratified epitheliaJ Cell Sci199097pt 22472572277092
   PubMedGoogle Scholar
• DelvaETuckerDKKowalczykAPThe desmosomeCold Spring Harb Perspect Biol200912a00254320066089
   PubMed Web of Science ®Google Scholar
• ChunMGHanahanDGenetic deletion of the desmosomal component desmoplakin promotes tumor microinvasion in a mouse model of pancreatic neuroendocrine carcinogenesisPLoS Genet201069e100112020862307
   PubMedGoogle Scholar
• WanHSouthAPHartIRIncreased keratinocyte proliferation initiated through downregulation of desmoplakin by RNA interferenceExp Cell Res2007313112336234417475244
   PubMedGoogle Scholar
• YangLChenYCuiTDesmoplakin acts as a tumor suppressor by inhibition of the Wnt/beta-catenin signaling pathway in human lung cancerCarcinogenesis201233101863187022791817
   PubMedGoogle Scholar