Identification of the anticancer effects of a novel proteasome inhibitor, ixazomib, on colorectal cancer using a combined method of microarray and bioinformatics analysis

References

• FerlayJSoerjomataramIDikshitRCancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012Int J Cancer20151365E359E38625220842
   PubMed Web of Science ®Google Scholar
• KassahunWTUnresolved issues and controversies surrounding the management of colorectal cancer liver metastasisWorld J Surg Oncol2015136125890279
   PubMedGoogle Scholar
• FatemiSRPourhoseingholiMAAsadiFRecurrence and five-year survival in colorectal cancer patients after surgeryIran J Cancer Prev201584e343926478796
   PubMedGoogle Scholar
• MarinJJSanchez de MedinaFCastañoBChemoprevention, chemotherapy, and chemoresistance in colorectal cancerDrug Metab Rev201244214817222497631
   PubMed Web of Science ®Google Scholar
• HershkoACiechanoverAThe ubiquitin systemAnnu Rev Biochem1998674254799759494
   PubMed Web of Science ®Google Scholar
• PickartCMMechanisms underlying ubiquitinationAnnu Rev Biochem20017050353311395416
   PubMed Web of Science ®Google Scholar
• GoldbergALProtein degradation and protection against misfolded or damaged proteinsNature2003426696889589914685250
   PubMed Web of Science ®Google Scholar
• CiechanoverAProteolysis: from the lysosome to ubiquitin and the proteasomeNat Rev Mol Cell Biol200561798715688069
   PubMed Web of Science ®Google Scholar
• OrlowskiRZKuhnDJProteasome inhibitors in cancer therapy: lessons from the first decadeClin Cancer Res20081461649165718347166
   PubMed Web of Science ®Google Scholar
• DaltonWSThe proteasomeSemin Oncol2004316 suppl 1639 discussion 33
   PubMed Web of Science ®Google Scholar
• DelicJMasdehorsPOmuraSThe proteasome inhibitor lactacystin induces apoptosis and sensitizes chemo- and radioresistant human chronic lymphocytic leukaemia lymphocytes to TNF-alpha-initiated apoptosisBr J Cancer1998777110311079569046
   PubMed Web of Science ®Google Scholar
• OrlowskiRZEswaraJRLafond-WalkerAGreverMROrlowskiMDangCVTumor growth inhibition induced in a murine model of human Burkitt’s lymphoma by a proteasome inhibitorCancer Res19985819434243489766662
   PubMed Web of Science ®Google Scholar
• LeBlancRCatleyLPHideshimaTProteasome inhibitor PS-341 inhibits human myeloma cell growth in vivo and prolongs survival in a murine modelCancer Res200262174996500012208752
   PubMed Web of Science ®Google Scholar
• FoodUSAdministrationDrugFDA approves Ninlaro, new oral medication to treat multiple myeloma [press release]20151120 Available from: www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm473771.htmAccessed December 11, 2015
   Google Scholar
• ShirleyMIxazomib: first global approvalDrugs201676340541126846321
   PubMed Web of Science ®Google Scholar
• PaulusAMasoodAMillerKCThe investigational agent MLN2238 induces apoptosis and is cytotoxic to CLL cells in vitro, as a single agent and in combination with other drugsBr J Haematol20141651788824467634
   PubMedGoogle Scholar
• WeiXZhouPLinXMLN2238 synergizes BH3 mimetic ABT-263 in castration-resistant prostate cancer cells by induction of NOXATumour Biol20143510102131022125027405
   PubMedGoogle Scholar
• WangHYuYJiangZNext-generation proteasome inhibitor MLN9708 sensitizes breast cancer cells to doxorubicin-induced apoptosisSci Rep201662645627217076
   PubMedGoogle Scholar
• LiHChenZHuTNovel proteasome inhibitor ixazomib sensitizes neuroblastoma cells to doxorubicin treatmentSci Rep201663439727687684
   PubMedGoogle Scholar
• GautierLCopeLBolstadBMIrizarryRAaffy – analysis of Affymetrix GeneChip data at the probe levelBioinformatics200420330731514960456
   PubMed Web of Science ®Google Scholar
• IrizarryRAHobbsBCollinFExploration, normalization, and summaries of high density oligonucleotide array probe level dataBiostatistics20034224926412925520
   PubMed Web of Science ®Google Scholar
• SmythGKLimma: linear models for microarray dataGentlemanRCareyVJHuberWIrizarryRADudoitSBioinformatics and Computational Biology Solutions Using R and BioconductorNew York, NYSpringer2005397420
   Google Scholar
• Kolde R [webpage on the Internet]Pheatmap: Pretty heatmaps. R package version 1.0.82015 Available from: https://cran.r-project.org/web/packages/pheatmap/index.htmlAccessed May 14, 2016
   Google Scholar
• AshburnerMBallCABlakeJAGene ontology: tool for the unification of biology. The Gene Ontology ConsortiumNat Genet2000251252910802651
   PubMed Web of Science ®Google Scholar
• KanehisaMGotoSKEGG: kyoto encyclopedia of genes and genomesNucleic Acids Res2000281273010592173
   PubMed Web of Science ®Google Scholar
• DennisGJrShermanBTHosackDADAVID: database for annotation, visualization, and integrated discoveryGenome Biol2003453
   PubMed Web of Science ®Google Scholar
• WuJMaoXCaiTLuoJWeiLKOBAS server: a web-based platform for automated annotation and pathway identificationNucleic Acids Res200634Web Server issueW720W72416845106
   PubMed Web of Science ®Google Scholar
• SzklarczykDFranceschiniAWyderSSTRING v10: protein–protein interaction networks, integrated over the tree of lifeNucleic Acids Res201543Database issueD447D45225352553
   PubMed Web of Science ®Google Scholar
• ShannonPMarkielAOzierOCytoscape: a software environment for integrated models of biomolecular interaction networksGenome Res200313112498250414597658
   PubMed Web of Science ®Google Scholar
• ScardoniGPetterliniMLaudannaCAnalyzing biological network parameters with CentiScaPeBioinformatics200925212857285919729372
   PubMed Web of Science ®Google Scholar
• BaderGDHogueCWAn automated method for finding molecular complexes in large protein interaction networksBMC Bioinformatics20034212525261
   PubMed Web of Science ®Google Scholar
• ShinSSSongJHHwangBHSPA6 augments garlic extract-induced inhibition of proliferation, migration, and invasion of bladder cancer EJ cells; Implication for cell cycle dysregulation, signaling pathway alteration, and transcription factor-associated MMP-9 regulationPLoS One2017122e017186028187175
   PubMedGoogle Scholar
• TakahashiMFujitaMFurukawaYIsolation of a novel human gene, APCDD1, as a direct target of the beta-Catenin/T-cell factor 4 complex with probable involvement in colorectal carcinogenesisCancer Res200262205651565612384519
   PubMedGoogle Scholar
• LamkanfiMKannegantiTDCaspase-7: a protease involved in apoptosis and inflammationInt J Biochem Cell Biol2010421212419782763
   PubMed Web of Science ®Google Scholar
• LuoYHurwitzJMassaguéJCell-cycle inhibition by independent CDK and PCNA binding domains in p21Cip1Nature199537565271591617753174
   PubMed Web of Science ®Google Scholar
• GartelALSerfasMSTynerALp21 – negative regulator of the cell cycleProc Soc Exp Biol Med199621321381498931660
   PubMedGoogle Scholar
• BunzFDutriauxALengauerCRequirement for p53 and p21 to sustain G2 arrest after DNA damageScience19982825393149715019822382
   PubMed Web of Science ®Google Scholar
• BouaounLSonkinDArdinMTP53 variations in human cancers: new lessons from the IARC TP53 database and genomics dataHum Mutat201637986587627328919
   PubMed Web of Science ®Google Scholar
• MullerPAVousdenKHp53 mutations in cancerNat Cell Biol20131512823263379
   PubMed Web of Science ®Google Scholar
• OrenMRotterVMutant p53 gain-of-function in cancerCold Spring Harb Perspect Biol201022a00110720182618
   PubMed Web of Science ®Google Scholar
• VogtPKBosTJThe oncogene jun and nuclear signallingTrends Biochem Sci19891451721752505415
   PubMedGoogle Scholar
• KoutseliniHMalliriAPapadakisEGillespieDSpandidosDC-jun oncogene expression in nonsmall cell lung-cancerOncol Rep19941235335621607364
   PubMedGoogle Scholar
• AlveroABHeatonALimaETRX-E-002-1 induces c-Jun-dependent apoptosis in ovarian cancer stem cells and prevents recurrence in vivoMol Cancer Ther20161561279129027196760
   PubMedGoogle Scholar
• JiaLYuWWangPLiJSandersBGKlineKCritical roles for JNK, c-Jun, and Fas/FasL-signaling in vitamin E analog-induced apoptosis in human prostate cancer cellsProstate200868442744118196534
   PubMedGoogle Scholar
• FanFTononGBashariMHTargeting Mcl-1 for multiple myeloma (MM) therapy: drug-induced generation of Mcl-1 fragment Mcl-1(128-350) triggers MM cell death via c-Jun upregulationCancer Lett2014343228629424120758
   PubMedGoogle Scholar
• RathinamRAlahariSKImportant role of integrins in the cancer biologyCancer Metastasis Rev201029122323720112053
   PubMedGoogle Scholar
• RamirezNEZhangZMadamanchiAThe α2β1 integrin is a metastasis suppressor in mouse models and human cancerJ Clin Invest2011121122623721135504
   PubMed Web of Science ®Google Scholar
• LindmarkGGerdinBPåhlmanLGlimeliusBGehlsenKRubinKInterconnection of integrins alpha 2 and alpha 3 and structure of the basal membrane in colorectal cancer: relation to survivalEur J Surg Oncol199319150608436241
   PubMedGoogle Scholar
• ChoRJHuangMCampbellMJTranscriptional regulation and function during the human cell cycleNat Genet2001271485411137997
   PubMed Web of Science ®Google Scholar
• FanFJinSAmundsonSAATF3 induction following DNA damage is regulated by distinct signaling pathways and over-expression of ATF3 protein suppresses cells growthOncogene200221497488749612386811
   PubMedGoogle Scholar
• HaiTHartmanMGThe molecular biology and nomenclature of the activating transcription factor/cAMP responsive element binding family of transcription factors: activating transcription factor proteins and homeostasisGene2001273111111483355
   PubMed Web of Science ®Google Scholar
• LiangGWolfgangCDChenBPChenTHHaiTATF3 gene. Genomic organization, promoter, and regulationJ Biol Chem19962713169517018576171
   PubMedGoogle Scholar
• TianZAnNZhouBXiaoPKohaneISWuECytotoxic diarylheptanoid induces cell cycle arrest and apoptosis via increasing ATF3 and stabilizing p53 in SH-SY5Y cellsCancer Chemother Pharmacol20096361131113918836721
   PubMedGoogle Scholar
• LiuYGaoFJiangHInduction of DNA damage and ATF3 by retigeric acid B, a novel topoisomerase II inhibitor, promotes apoptosis in prostate cancer cellsCancer Lett20133371667623693077
   PubMedGoogle Scholar
• LeeSHMinKWZhangXBaekSJ3,3′-diindolylmethane induces activating transcription factor 3 (ATF3) via ATF4 in human colorectal cancer cellsJ Nutr Biochem201324466467122819556
   PubMedGoogle Scholar
• SongHMParkGHEoHJJeongJBNaringenin-mediated ATF3 expression contributes to apoptosis in human colon cancerBiomol Ther (Seoul)201624214014626797111
   PubMedGoogle Scholar
• TangWSuGLiJEnhanced anti-colorectal cancer effects of carfilzomib combined with CPT-11 via downregulation of nuclear factor-κB in vitro and in vivoInt J Oncol2014453995101024968890
   PubMedGoogle Scholar