47
Views
4
CrossRef citations to date
0
Altmetric
Original Research

Frequency and clinical relevance of EGFR mutations and EML4–ALK translocations in octogenarians with non-small cell lung cancer

, , , , , , , , & show all
Pages 5179-5186 | Published online: 25 Oct 2017

References

  • SequistLVYangJCYamamotoMPhase III study of afatinib or cisplatin plus pemetrexed in patients with metastatic lung adenocarcinoma with EGFR mutationsJ Clin Oncol201331273327333423816960
  • SolomonBMokTKimD-WFirst-line crizotinib versus chemotherapy in ALK-positive lung cancerN Engl J Med2014371232167217725470694
  • MitsudomiTMoritaSYatabeYGefitinib versus cisplatin plus docetaxel in patients with non-small-cell lung cancer harbouring mutations of the epidermal growth factor receptor (WJTOG3405): an open label, randomised phase 3 trialLancet Oncol201011212112820022809
  • MaemondoMInoueAKobayashiKGefitinib or chemotherapy for non-small-cell lung cancer with mutated EGFRN Engl J Med2010362252380238820573926
  • Bericht zum Krebsgeschehen in Deutschland 2016 [webpage on the Inter-net]Zentrum für Krebsregisterdaten im Robert Koch-Institut (Hrsg). [Cancer in Germany Report]Berlin2016 Available from: http://www.krebsdaten.de/Krebs/DE/Content/Publikationen/Krebsgeschehen/Krebsgeschehen_node.htmlAccessed January 15, 2017 German
  • NovelloSBarlesiFCalifanoRMetastatic non-small-cell lung cancer: ESMO clinical practice guidelinesAnn Oncol201627suppl 5v1v2727664245
  • MastersGATeminSAzzoliCGSystemic therapy for stage IV non–small-cell lung cancer updateJCO2015333034883517
  • EnewoldLThomasAReal-world patterns of EGFR testing and treatment with erlotinib for non-small cell lung cancer in the United StatesPLoS One2016116e015672827294665
  • SchuetteWSchirmacherPEberhardtWEGFR mutation status and first-line treatment in patients with stage III/IV non-small-cell lung cancer in Germany: an observational studyCancer Epidemiol Biomark Prev201524812541261
  • TufmanALEdelmannMGamarraFPreselection based on clinical characteristics in German non–small-cell lung cancer patients screened for EML4-ALK translocationJ Thorac Oncol20149110911324346098
  • DriverJADjousséLLogroscinoGGazianoJMKurthTIncidence of cardiovascular disease and cancer in advanced age: prospective cohort studyBMJ2008337a246719066258
  • HowladerNNooneAKrapchoM webpage on the InternetPrevious Version: SEER Cancer Statistics Review, 1975–2013Bethesda, MDNational Cancer Institute Available from: http://seer.cancer.gov/csr/1975_2013/Accessed August 30, 2017 Based on November 2015. SEER data submission, posted to the SEER web site, April 2016
  • SmithDWECancer mortality at very old agesCancer1996777136713728608517
  • CDC [webpage on the Internet]Tobacco-Related Mortality Available from: https://www.cdc.gov/tobacco/data_statistics/fact_sheets/health_effects/tobacco_related_mortality/Accessed January 15, 2017
  • PirieKPetoRReevesGGreenJBeralVMillion Women Study CollaboratorsThe 21st century hazards of smoking and benefits of stopping: a prospective study of one million women in the UKLancet2013381986113314123107252
  • TafaroLCicconettiPTedeschiGSmoking and longevity: an incompatible binomial?Arch Gerontol Geriatr Suppl20049425430
  • LampertTvon der LippeEMütersSPrevalence of smoking in the adult population of Germany. Results of the German Health Interview and Examination Survey for Adults (DEGS1)Bundesgesundheitsbl201356802808
  • ErcegPMilosevicDPDespotovicNChromosomal changes in ageingJ Genet200786327727818305347
  • FormanDEBermanADMcCabeGHPTCA in the elderly: the “young-old” versus the “old-old”J Am Geriatr Soc199240119221727842
  • LyketsosCGWeillerEKatonaCGorwoodPAre old-old patients with major depression more likely to relapse than young-old patients during continuation treatment with escitalopram?BMC Geriatr201111221235759
  • AzimHANguyenBBrohéeSGenomic aberrations in young and elderly breast cancer patientsBMC Med20151326626467651
  • JanjigianYMcDonnellKKrisMPack years of cigarette smoking as a prognostic factor in patients with stage IIIB/IV non-small cell lung cancerCancer2010116367067520029977
  • NishiiTYokoseTMiyageYClinicopathological features and EGFR gene mutation status in elderly patients with resected non-small cell lung cancerBMC Cancer20141461025152277
  • BlanchardEMArnaoutakisKHeskethPJLung cancer in octogenariansJ Thorac Oncol20105690991620521358
  • OxnardGRFidiasPMuzikanskyASequistLVNon-small cell lung cancer in octogenarians: treatment practices and preferencesJ Thorac Oncol20072111029103517975495
  • ChenKYChenJHShihJYYangCHYuCJYangPCOctogenarians with advanced non-small cell lung cancer: treatment modalities, survival, and prognostic factorsJ Thorac Oncol201051828919884854
  • AyyappanSGonzalezCYarlagaddaRZakhariaYWoodlockTJLung cancer in the very elderly: incidence, presentation, and diagnostic decision-making. A retrospective analysis at a teaching community hospitalJ Community Hosp Intern Med Perspect20111316
  • SacherAGDahlbergSEHengJAssociation between younger age and targetable genomic alterations and prognosis in non-small-cell lung cancerJAMA Oncol20162331332026720421
  • PaoWMillerVZakowskiMEGF receptor gene mutations are common in lung cancers from “never smokers” and are associated with sensitivity of tumors to gefitinib and erlotinibProc Natl Acad Sci U S A200410136133061331115329413