Inhibitory effects of a selective Jak2 inhibitor on adrenocorticotropic hormone production and proliferation of corticotroph tumor AtT20 cells

References

• NiemanLKBillerBMFindlingJWThe diagnosis of Cushing’s syndrome: an Endocrine Society clinical practice guidelineJ Clin Endocrinol Metab20089351526154018334580
   PubMed Web of Science ®Google Scholar
• KageyamaKOkiYSakiharaSNigawaraTTeruiKSudaTEvaluation of the diagnostic criteria for Cushing’s disease in JapanEndocr J201360212713523171704
   PubMedGoogle Scholar
• BillerBMGrossmanABStewartPMTreatment of adrenocorticotropin-dependent Cushing’s syndrome: a consensus statementJ Clin Endocrinol Metab20089372454346218413427
   PubMed Web of Science ®Google Scholar
• RhodePRGorskiJGrowth and cell cycle regulation of mRNA levels in GH3 cellsMol Cell Endocrinol199182111221761163
   PubMedGoogle Scholar
• BertagnaXGuignatLApproach to the Cushing’s disease patient with persistent/recurrent hypercortisolism after pituitary surgeryJ Clin Endocrinol Metab20139841307131823564942
   PubMed Web of Science ®Google Scholar
• SchteingartDEDrugs in the medical treatment of Cushing’s syndromeExpert Opin Emerg Drugs200914466167119939210
   PubMed Web of Science ®Google Scholar
• KageyamaKSugiyamaAMurasawaSAphidicolin inhibits cell proliferation via the p53-GADD45β pathway in AtT-20 cellsEndocr J201562764565425948499
   PubMedGoogle Scholar
• PeiLMelmedSIsolation and characterization of a pituitary tumor-transforming gene (PTTG)Mol Endocrinol19971144334419092795
   PubMedGoogle Scholar
• ZhangXHorwitzGAHeaneyAPPituitary tumor transforming gene (PTTG) expression in pituitary adenomasJ Clin Endocrinol Metab199984276176710022450
   PubMedGoogle Scholar
• ChesnokovaVZonisSZhouCLineage-specific restraint of pituitary gonadotroph cell adenoma growthPLoS One201163e1792421464964
   PubMedGoogle Scholar
• HernándezALópez-LluchGBernalJANavasPPintor-ToroJADicoumarol down-regulates human PTTG1/Securin mRNA expression through inhibition of Hsp90Mol Cancer Ther20087347448218347135
   PubMedGoogle Scholar
• ChesnokovaVZonisSWawrowskyKClusterin and FOXL2 act concordantly to regulate pituitary gonadotroph adenoma growthMol Endocrinol201226122092210323051594
   PubMedGoogle Scholar
• NakadaYKageyamaKSugiyamaAInhibitory effects of trichostatin A on adrenocorticotropic hormone production and proliferation of corticotroph tumor AtT-20 cellsEndocr J201562121083109026497760
   PubMedGoogle Scholar
• HernándezALópez-LluchGNavasPPintor-ToroJAHDAC and Hsp90 inhibitors down-regulate PTTG1/securin but do not induce aneuploidyGenes Chromosomes Cancer200948219420119006077
   PubMedGoogle Scholar
• HoffmanBLiebermannDAGadd45 in modulation of solid tumors and leukemiaAdv Exp Med Biol2013793213324104471
   PubMed Web of Science ®Google Scholar
• MichaelisKAKnoxAJXuMIdentification of growth arrest and DNA-damage-inducible gene β (GADD45 β) as a novel tumor suppressor in pituitary gonadotrope tumorsEndocrinology2011152103603361321810943
   PubMed Web of Science ®Google Scholar
• ReinckeMSbieraSHayakawaAMutations in the deubiquitinase gene USP8 cause Cushing’s diseaseNat Genet2015471313825485838
   PubMed Web of Science ®Google Scholar
• DuanZBradnerJEGreenbergESD-1029 inhibits signal transducer and activator of transcription 3 nuclear translocationClin Cancer Res200612226844685217121906
   PubMedGoogle Scholar
• YangCSchwabJHSchoenfeldAJA novel target for treatment of chordoma: signal transducers and activators of transcription 3Mol Cancer Ther2009892597260519723879
   PubMed Web of Science ®Google Scholar
• KageyamaKHanadaKSudaTDifferential regulation of urocortins1–3 mRNA in human umbilical vein endothelial cellsRegul Pept20091551–313113819254747
   PubMedGoogle Scholar
• KageyamaKHanadaKSudaTDifferential regulation and roles of urocortins in human adrenal H295R cellsRegul Pept20101621–3182520171993
   PubMedGoogle Scholar
• YamagataSKageyamaKAkimotoKWatanukiYSudaTDaimonMRegulation of corticotropin-releasing factor and urocortin 2/3 mRNA by leptin in hypothalamic N39 cellsPeptides2013501724083959
   PubMedGoogle Scholar
• MurasawaSKageyamaKSugiyamaAInhibitory effects of SOM230 on adrenocorticotropic hormone production and corticotroph tumor cell proliferation in vitro and in vivoMol Cell Endocrinol20143941–2374625011056
   PubMedGoogle Scholar
• TanaseCAlbulescuRCodriciEDecreased expression of APAF-1 and increased expression of cathepsin B in invasive pituitary adenomaOnco Targets Ther20148819025565868
   PubMed Web of Science ®Google Scholar
• TanaseCPNeaguMAlbulescuRKey signaling molecules in pituitary tumorsExpert Rev Mol Diagn20099885987719895231
   PubMed Web of Science ®Google Scholar
• SugiyamaAKageyamaKMurasawaSIshigameNNiiokaKDaimonMInhibition of heat shock protein 90 decreases ACTH production and cell proliferation in AtT-20 cellsPituitary2014184542553
   Google Scholar
• FukuokaHCooperOBen-ShlomoAEGFR as a therapeutic target for human, canine, and mouse ACTH-secreting pituitary adenomasJ Clin Invest2011121124712472122105169
   PubMed Web of Science ®Google Scholar
• AndlCDMizushimaTOyamaKBowserMNakagawaHRustgiAKEGFR-induced cell migration is mediated predominantly by the JAK-STAT pathway in primary esophageal keratinocytesAm J Physiol Gastrointest Liver Physiol20042876G1227G123715284024
   PubMed Web of Science ®Google Scholar
• ZhengQHanLDongYJAK2/STAT3 targeted therapy suppresses tumor invasion via disruption of the EGFRvIII/JAK2/STAT3 axis and associated focal adhesion in EGFRvIII-expressing glioblastomaNeuro Oncol20141691229124324861878
   PubMedGoogle Scholar
• CruceruMLEnciuAMPopaACSignal transduction molecule patterns indicating potential glioblastoma therapy approachesOnco Targets Ther201361737174924348050
   PubMed Web of Science ®Google Scholar
• XuAWSte-MarieLKaelinCBBarshGSInactivation of signal transducer and activator of transcription 3 in proopiomelanocortin (Pomc) neurons causes decreased Pomc expression, mild obesity, and defects in compensatory refeedingEndocrinology20071481728017023536
   PubMedGoogle Scholar
• BousquetCZatelliMCMelmedSDirect regulation of pituitary proopiomelanocortin by STAT3 provides a novel mechanism for immuno-neuroendocrine interfacingJ Clin Invest2000106111417142511104795
   PubMedGoogle Scholar